ES2076477T3 - Nuevos derivados de indol e indolina. - Google Patents

Nuevos derivados de indol e indolina.

Info

Publication number
ES2076477T3
ES2076477T3 ES91308365T ES91308365T ES2076477T3 ES 2076477 T3 ES2076477 T3 ES 2076477T3 ES 91308365 T ES91308365 T ES 91308365T ES 91308365 T ES91308365 T ES 91308365T ES 2076477 T3 ES2076477 T3 ES 2076477T3
Authority
ES
Spain
Prior art keywords
indolina
indol
alkyl
new derivatives
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91308365T
Other languages
English (en)
Inventor
Jeremy Gilmore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Application granted granted Critical
Publication of ES2076477T3 publication Critical patent/ES2076477T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN COMPUESTO FARMACEUTICO DE LA FORMULA EN LA QUE A ESTA SELECCIONADA DE -NHCOR ELEVADO 1, -NHCOOR ELEVADO 1, -NHCONHR ELEVADO 1, -NHCSNHR ELEVADO 1, -CONHR ELEVADO 1, EN DONDE R ELEVADO 1 ES OPCIONALMENTE HALO-SUBSTITUIDO C SUB 1 10 ALQUILO, C SUB 2 10 ALQUENIL, C SUB 3 7 CICLOALQUIL-C SUB 1 4 ALQUILO O FENIL-C SUB 1 4 ALQUILO B ES OPCIONALMENTE FENIL SUBSTITUIDO Y -X-Y LOS COMPUESTOS SON ANTAGONISTAS LEUCOTRIENOS.
ES91308365T 1990-09-18 1991-09-12 Nuevos derivados de indol e indolina. Expired - Lifetime ES2076477T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909020338A GB9020338D0 (en) 1990-09-18 1990-09-18 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
ES2076477T3 true ES2076477T3 (es) 1995-11-01

Family

ID=10682362

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91308365T Expired - Lifetime ES2076477T3 (es) 1990-09-18 1991-09-12 Nuevos derivados de indol e indolina.

Country Status (10)

Country Link
US (1) US5185361A (es)
EP (1) EP0476935B1 (es)
JP (1) JP3046861B2 (es)
AT (1) ATE125530T1 (es)
CA (1) CA2051460C (es)
DE (1) DE69111541T2 (es)
DK (1) DK0476935T3 (es)
ES (1) ES2076477T3 (es)
GB (1) GB9020338D0 (es)
GR (1) GR3017390T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998015530A1 (en) * 1996-10-08 1998-04-16 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
WO1999000372A1 (fr) * 1997-06-27 1999-01-07 Fujisawa Pharmaceutical Co., Ltd. Sulfamides et leur utilisation medicale
EP1283199A4 (en) * 2000-05-16 2003-12-17 Takeda Chemical Industries Ltd MELANINE CONCENTRATING HORMONE ANTAGONISTS
KR20050059294A (ko) * 2002-10-24 2005-06-17 스테릭스 리미티드 11-베타-하이드록시 스테로이드 데하이드로게나제 형태 1및 형태 2의 억제제
GB0224830D0 (en) * 2002-10-24 2002-12-04 Sterix Ltd Compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448784A (en) * 1982-04-12 1984-05-15 Hoechst-Roussel Pharmaceuticals, Inc. 1-(Aminoalkylphenyl and aminoalkylbenzyl)-indoles and indolines and analgesic method of use thereof
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
GB8707051D0 (en) * 1986-04-15 1987-04-29 Ici America Inc Heterocyclic carboxamides
GB8927981D0 (en) * 1989-12-11 1990-02-14 Ici Plc Carbamoyl derivative

Also Published As

Publication number Publication date
ATE125530T1 (de) 1995-08-15
EP0476935B1 (en) 1995-07-26
JPH04230661A (ja) 1992-08-19
DK0476935T3 (da) 1995-09-11
CA2051460A1 (en) 1992-03-19
DE69111541T2 (de) 1996-01-18
EP0476935A1 (en) 1992-03-25
CA2051460C (en) 2002-01-22
GR3017390T3 (en) 1995-12-31
US5185361A (en) 1993-02-09
JP3046861B2 (ja) 2000-05-29
DE69111541D1 (de) 1995-08-31
GB9020338D0 (en) 1990-10-31

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