ATE129744T1 - Rekombinantes c-terminal alpha amidatierungsenzym von menschlischem thyroidursprung. - Google Patents

Rekombinantes c-terminal alpha amidatierungsenzym von menschlischem thyroidursprung.

Info

Publication number: ATE129744T1
Authority: AT; Austria
Prior art keywords: protein; terminal alpha; alpha; human thyroid; recombinant
Prior art date: 1989-01-17

Application number

AT90901894T

Other languages

English (en)

Inventor

Kazuhiro Ohsuye

Katsuhiko Kitano

Shoji Tanaka

Original Assignee

Suntory Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-17

Filing date

1990-01-17

Publication date

1995-11-15

1990-01-17 Application filed by Suntory Ltd filed Critical Suntory Ltd

1995-11-15 Application granted granted Critical

1995-11-15 Publication of ATE129744T1 publication Critical patent/ATE129744T1/de

Links

102000004190 Enzymes Human genes 0.000 title abstract 3
108090000790 Enzymes Proteins 0.000 title abstract 3
210000001685 thyroid gland Anatomy 0.000 title abstract 2
230000002862 amidating effect Effects 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 4
108090000623 proteins and genes Proteins 0.000 abstract 4
102000004169 proteins and genes Human genes 0.000 abstract 4
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 3
150000001413 amino acids Chemical class 0.000 abstract 2
210000004899 c-terminal region Anatomy 0.000 abstract 2
239000004471 Glycine Substances 0.000 abstract 1
239000013604 expression vector Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/17—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced ascorbate as one donor, and incorporation of one atom of oxygen (1.14.17)
- C12Y114/17003—Peptidylglycine monooxygenase (1.14.17.3)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

AT90901894T 1989-01-17 1990-01-17 Rekombinantes c-terminal alpha amidatierungsenzym von menschlischem thyroidursprung. ATE129744T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP1005878A JP2845468B2 (ja)	1989-01-17	1989-01-17	ヒト甲状腺由来Ｃ―末端α―アミド化酵素

Publications (1)

Publication Number	Publication Date
ATE129744T1 true ATE129744T1 (de)	1995-11-15

Family

ID=11623165

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90901894T ATE129744T1 (de)	1989-01-17	1990-01-17	Rekombinantes c-terminal alpha amidatierungsenzym von menschlischem thyroidursprung.

Country Status (10)

Country	Link
EP (1)	EP0404967B1 (de)
JP (1)	JP2845468B2 (de)
KR (1)	KR970001567B1 (de)
AT (1)	ATE129744T1 (de)
AU (1)	AU631843B2 (de)
CA (1)	CA2024279C (de)
DE (1)	DE69023284T2 (de)
DK (1)	DK0404967T3 (de)
ES (1)	ES2078964T3 (de)
WO (1)	WO1990008190A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6319685B1 (en)	1984-09-27	2001-11-20	Unigene Laboratories, Inc.	Alpha-amidating enzyme compositions and processes for their production and use
US5789234A (en) *	1987-08-14	1998-08-04	Unigene Laboratories, Inc.	Expression systems for amidating enzyme
CN1069699C (zh) *	1997-04-16	2001-08-15	中国科学院上海生物化学研究所	一种活性重组酰胺化酶及其对多肽的酰胺化修饰应用
ES2583259T3 (es) *	2009-12-01	2016-09-20	Novo Nordisk A/S	Nuevas liasas alfa-amidantes de peptidil alfa-hidroxiglicina

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4708934A (en) *	1984-09-27	1987-11-24	Unigene Laboratories, Inc.	α-amidation enzyme
JPH0775541B2 (ja) *	1986-06-07	1995-08-16	壽之松尾	Ｃ末端アミド化酵素及びその製造方法

1989
- 1989-01-17 JP JP1005878A patent/JP2845468B2/ja not_active Expired - Fee Related
1990
- 1990-01-17 CA CA002024279A patent/CA2024279C/en not_active Expired - Fee Related
- 1990-01-17 AT AT90901894T patent/ATE129744T1/de not_active IP Right Cessation
- 1990-01-17 WO PCT/JP1990/000042 patent/WO1990008190A1/en not_active Ceased
- 1990-01-17 ES ES90901894T patent/ES2078964T3/es not_active Expired - Lifetime
- 1990-01-17 KR KR1019900702040A patent/KR970001567B1/ko not_active Expired - Fee Related
- 1990-01-17 EP EP90901894A patent/EP0404967B1/de not_active Expired - Lifetime
- 1990-01-17 AU AU49493/90A patent/AU631843B2/en not_active Ceased
- 1990-01-17 DK DK90901894.7T patent/DK0404967T3/da active
- 1990-01-17 DE DE69023284T patent/DE69023284T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0404967B1 (de)	1995-11-02
DK0404967T3 (da)	1995-12-04
KR910700345A (ko)	1991-03-14
AU4949390A (en)	1990-08-13
ES2078964T3 (es)	1996-01-01
WO1990008190A1 (en)	1990-07-26
CA2024279C (en)	2000-07-11
JPH02190183A (ja)	1990-07-26
AU631843B2 (en)	1992-12-10
KR970001567B1 (ko)	1997-02-11
JP2845468B2 (ja)	1999-01-13
DE69023284T2 (de)	1996-03-28
CA2024279A1 (en)	1990-07-18
EP0404967A1 (de)	1991-01-02
DE69023284D1 (de)	1995-12-07

Similar Documents

Publication	Publication Date	Title
DE69522216D1 (de)	2001-09-20	Zielzellen-bindende chimäre Peptide
MD1652G2 (ro)	2001-12-31	Proteină cu activitate de tip citochină, ADN recombinant, codificator pentru această proteină, celule şi microorganisme transformate, vector de expresie, procedeu de obţinere a proteinei şi remediu care conţine această proteină
DE112006000677A5 (de)	2007-12-27	Rekombinante Expression von Proteinen in einer disulfidverbrückten, zweikettigen Form
SE9100799D0 (sv)	1991-03-15	Recombinant human factor viii derivatives
DK105489D0 (da)	1989-03-03	Polypeptid
ES2054365T3 (es)	1994-08-01	Inhibicion de la via de la regla del n final en celulas vivas.
ATE386118T1 (de)	2008-03-15	Cnp-gen und vorläuferprotein aus schwein
ES2112255T3 (es)	1998-04-01	Complejos proteicos que tienen actividad del factor viii:c y su produccion.
FI961044A0 (fi)	1996-03-06	Kininogeeni-inhibiittorit
ES2065907T3 (es)	1995-03-01	Procedimiento para la produccion de un peptido fisiologicamente activo que contiene un resto cisteina.
BR9306272A (pt)	1998-06-23	Peptídeo e composiçao farmacêutica
Canova-Davis et al.	1991	Transpeptidation during the analytical proteolysis of proteins
ES2056753A6 (es)	1994-10-01	Un procedimiento para la produccion de un polipeptido que tiene actividad de factor quemotactico de monocitos humanos.
ATE129744T1 (de)	1995-11-15	Rekombinantes c-terminal alpha amidatierungsenzym von menschlischem thyroidursprung.
NO20012232L (no)	2001-05-04	Enzymatisk amidering av peptider
DE69623635D1 (de)	2002-10-17	Mu-opioidligande: agonisten und antagonisten
ES2072422T3 (es)	1995-07-16	Procedimiento para la produccion de peptidos amidados en alfa en el terminal c.
DE3686257D1 (de)	1992-09-03	Herstellung von polypeptiden.
DE69832299D1 (de)	2005-12-15	Einkettigen polypeptiden enthalten troponin i und troponin c
Kiso et al.	1983	Neo‐kyotorphin (Thr—Ser—Lys—Tyr—Arg), a new analgesic peptide
HU912398D0 (en)	1991-12-30	An in-vitro process for fusion of proteins
ATE92078T1 (de)	1993-08-15	Pharmakologisch aktive peptide.
AU8302791A (en)	1992-02-18	Recombinant gene coding for a protein having an endochitinase activity
ES2158235T3 (es)	2001-09-01	Peptidos antigenicos con substituciones de glicina.
FR2268792A1 (en)	1975-11-21	Peptides enzymatic synthesis - by reacting peptide free acids with amino acids or peptides in the presence of pepsin

Legal Events

Date	Code	Title
1996-05-15	UEP	Publication of translation of european patent specification
2004-03-15	EEIH	Change in the person of patent owner
2006-10-15	REN	Ceased due to non-payment of the annual fee