ATE132741T1 - Medikament zum halten ophthalmologischer mittel im augengewebe und verfahren zu seiner herstellung - Google Patents

Medikament zum halten ophthalmologischer mittel im augengewebe und verfahren zu seiner herstellung

Info

Publication number
ATE132741T1
ATE132741T1 AT91710003T AT91710003T ATE132741T1 AT E132741 T1 ATE132741 T1 AT E132741T1 AT 91710003 T AT91710003 T AT 91710003T AT 91710003 T AT91710003 T AT 91710003T AT E132741 T1 ATE132741 T1 AT E132741T1
Authority
AT
Austria
Prior art keywords
medication
maintaining
production
eye tissue
ophthalmological
Prior art date
Application number
AT91710003T
Other languages
English (en)
Inventor
Judah Dr Folkman
Original Assignee
Childrens Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center filed Critical Childrens Medical Center
Application granted granted Critical
Publication of ATE132741T1 publication Critical patent/ATE132741T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
AT91710003T 1990-03-07 1991-03-06 Medikament zum halten ophthalmologischer mittel im augengewebe und verfahren zu seiner herstellung ATE132741T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/489,680 US5227372A (en) 1990-03-07 1990-03-07 Method for retaining ophthalmological agents in ocular tissues

Publications (1)

Publication Number Publication Date
ATE132741T1 true ATE132741T1 (de) 1996-01-15

Family

ID=23944834

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91710003T ATE132741T1 (de) 1990-03-07 1991-03-06 Medikament zum halten ophthalmologischer mittel im augengewebe und verfahren zu seiner herstellung

Country Status (10)

Country Link
US (1) US5227372A (de)
EP (1) EP0447351B1 (de)
JP (1) JPH0729941B2 (de)
KR (1) KR910016315A (de)
AT (1) ATE132741T1 (de)
AU (1) AU636451B2 (de)
CA (1) CA2037624A1 (de)
DE (1) DE69116186D1 (de)
IE (1) IE910658A1 (de)
NZ (1) NZ237165A (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705178A (en) * 1991-05-31 1998-01-06 Gliatech, Inc. Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
WO1993005777A1 (fr) * 1991-09-18 1993-04-01 Fujisawa Pharmaceutical Co., Ltd. Preparation transoculaire
ATE205092T1 (de) * 1992-01-30 2001-09-15 Takeda Chemical Industries Ltd Verfahren zur herstellung hoch-wasserlöslicher zyklodextrinkomplexe
TW251236B (de) * 1992-09-10 1995-07-11 Ciba Vision Ag
US5328930A (en) * 1993-03-01 1994-07-12 Emory University Treatment of microsporidial and acanthamoeba keratoconjunctivitis with topical fumagillin
US5662919A (en) * 1994-11-21 1997-09-02 Alcon Laboratories, Inc. Sulfated polyvinyl alcohol polymers to stabilize pharmaceutical drug compounds
US5710148A (en) * 1995-03-06 1998-01-20 Senju Pharmaceuticals Co., Ltd. Corneal opacification inhibitory composition
US5744154A (en) * 1995-09-06 1998-04-28 Laboratoire Chauvin S.A. Ready-to-use indomethacin-based eye lotion
US5686095A (en) * 1995-10-23 1997-11-11 Price, Jr.; Francis W. Method of treating canker sores
DE19539532C2 (de) * 1995-10-24 1999-02-25 Mann Gerhard Chem Pharm Fab Ophthalmisches Cromoglicat-Gelpräparat
EP1003555A1 (de) * 1997-04-23 2000-05-31 The University of Otago Kontrollierte freisetzung von opthalmischen zusammensetzungen
US20040152664A1 (en) * 1998-09-02 2004-08-05 Allergan, Inc. Prednisolone compositions
JP2002523475A (ja) 1998-09-02 2002-07-30 アラーガン・セイルズ・インコーポレイテッド 防腐したシクロデキストリン含有組成物
ATE259231T1 (de) * 1999-04-29 2004-02-15 Alza Corp Liposomenzusammensetzungen zur verbesserten wirkstoffzurückhaltung
JP2001158750A (ja) * 1999-12-02 2001-06-12 Lion Corp 眼科用組成物及び抗アレルギー薬の持続性向上方法
US6265435B1 (en) 2000-03-07 2001-07-24 Hans Rosenkoetter Method for enhancing corneal penetration by water soluble ophthalmic drugs
RU2177801C1 (ru) * 2001-01-25 2002-01-10 Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" Средство, ингибирующее ангиогенез при заболеваниях органа зрения
US20030181416A1 (en) * 2002-01-10 2003-09-25 Comper Wayne D. Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof
US20040009953A1 (en) * 2002-01-10 2004-01-15 Comper Wayne D. Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof
EP1476135A1 (de) * 2002-02-22 2004-11-17 Pharmacia Corporation Ophthalmische formulierung mit gummi-system
EP1496916A2 (de) * 2002-04-09 2005-01-19 Greenville Hospital System Metastasen-modulierende wirkung von hochsulfierten oligosacchariden
US20050085446A1 (en) * 2003-04-14 2005-04-21 Babu M.K. M. Fluoroquinolone formulations and methods of making and using the same
WO2005004882A1 (en) * 2003-07-09 2005-01-20 Monash University Antiviral charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and methods of use thereof
US20050234018A1 (en) * 2004-04-15 2005-10-20 Allergan, Inc. Drug delivery to the back of the eye
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US8435544B2 (en) 2007-10-08 2013-05-07 Lux Biosciences, Inc. Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors
CL2008003120A1 (es) 2007-11-01 2009-10-09 Acucela Inc Compuestos derivados de fenilalquil-, fenilalquenil-, fenilalquinil- amina, feniltioalquilamina, fenilaminoalquilamina, fenilalcoxiamina y fenilalquilguanidina; composicion farmaceutica; y uso de los compuestos para tratar un trastorno o enfermedad oftalmologica tal como retinopatia, maculopatia, retinitis pigmentosa, uveitis, entre otras.
JP5890182B2 (ja) * 2009-02-12 2016-03-22 インセプト エルエルシー ヒドロゲルプラグによる薬物送達
WO2010144194A1 (en) * 2009-06-09 2010-12-16 Lux Biosciences, Inc. Topical drug delivery systems for ophthalmic use
US10413506B2 (en) 2010-04-03 2019-09-17 Praful Doshi Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia
WO2011123180A1 (en) 2010-04-03 2011-10-06 Praful Doshi Medical devices including medicaments and methods of making and using same
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
US9205150B2 (en) 2011-12-05 2015-12-08 Incept, Llc Medical organogel processes and compositions
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
CN110621320B (zh) 2017-05-17 2023-03-17 Tx医生公司 青光眼的治疗
EP3810659A1 (de) * 2018-06-20 2021-04-28 DuPont Industrial Biosciences USA, LLC Polysaccharidderivate und zusammensetzungen damit

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2923704A (en) * 1957-05-15 1960-02-02 Hoffmann La Roche Cycloamylose sulfates and derivatives thereof
US3754925A (en) * 1970-03-24 1973-08-28 Takeda Chemical Industries Ltd New thermo gelable polysaccharide containing foodstuffs
DK135268A (de) * 1973-02-09
JPS5036422A (de) * 1973-08-07 1975-04-05
JPS5366442A (en) * 1976-11-18 1978-06-13 Takuma Sasaki Antitumors
JPS5583798A (en) * 1978-12-19 1980-06-24 Takuma Sasaki (1,3)-beta-d-glucan derivative
EP0244178A3 (de) * 1986-04-28 1989-02-08 Iolab, Inc Intraokuläre Mittel und Verfahren zu deren Verwendung
EP0261719A3 (de) * 1986-09-23 1990-10-10 Akzo N.V. Thermochemischlumineszierende Komplexe von Cyclodextrinen
JP2577049B2 (ja) * 1987-06-04 1997-01-29 三共株式会社 シクロスポリン製剤
US4877778A (en) * 1987-07-01 1989-10-31 The Children's Medical Center Corporation Method of enhancing lipophile transport using cyclodextrin derivatives
US4877774A (en) * 1987-09-09 1989-10-31 The United States Of America As Represented By The Department Of Health And Human Services Administration of steroid hormones
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
DE3740838A1 (de) * 1987-11-27 1989-06-08 Schering Ag Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
EP0325199B1 (de) * 1988-01-19 1993-10-27 Takeda Chemical Industries, Ltd. Fumagillin als angiostatisches Mittel
CN1038304C (zh) * 1988-01-19 1998-05-13 摩塞斯·朱旦·福克迈 生长抑制组合物的制备方法
US5019562A (en) * 1988-01-19 1991-05-28 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Growth inhibiting agent and the use thereof
US5007967A (en) * 1988-08-15 1991-04-16 American Maize-Products Company Separation and purification of branched beta cyclodextrins

Also Published As

Publication number Publication date
JPH04211615A (ja) 1992-08-03
JPH0729941B2 (ja) 1995-04-05
US5227372A (en) 1993-07-13
AU636451B2 (en) 1993-04-29
KR910016315A (ko) 1991-11-05
EP0447351B1 (de) 1996-01-10
NZ237165A (en) 1992-10-28
CA2037624A1 (en) 1991-09-08
AU7139691A (en) 1991-09-12
DE69116186D1 (de) 1996-02-22
IE910658A1 (en) 1991-09-11
EP0447351A1 (de) 1991-09-18

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties