ATE132741T1 - Medikament zum halten ophthalmologischer mittel im augengewebe und verfahren zu seiner herstellung - Google Patents
Medikament zum halten ophthalmologischer mittel im augengewebe und verfahren zu seiner herstellungInfo
- Publication number
- ATE132741T1 ATE132741T1 AT91710003T AT91710003T ATE132741T1 AT E132741 T1 ATE132741 T1 AT E132741T1 AT 91710003 T AT91710003 T AT 91710003T AT 91710003 T AT91710003 T AT 91710003T AT E132741 T1 ATE132741 T1 AT E132741T1
- Authority
- AT
- Austria
- Prior art keywords
- medication
- maintaining
- production
- eye tissue
- ophthalmological
- Prior art date
Links
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229920001503 Glucan Polymers 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- COWYTPMAAISPHT-SWSWVKNJSA-A chembl411368 Chemical compound [K+].[K+].[K+].[K+].[K+].[K+].[K+].[K+].[K+].[K+].[K+].[K+].[K+].[K+].O1C(COS([O-])(=O)=O)[C@@H]2C(O)C(OS([O-])(=O)=O)[C@@H]1O[C@H](C(COS([O-])(=O)=O)O1)C(O)C(OS([O-])(=O)=O)[C@H]1O[C@H](C(COS([O-])(=O)=O)O1)C(O)C(OS([O-])(=O)=O)[C@H]1O[C@H](C(COS([O-])(=O)=O)O1)C(O)C(OS([O-])(=O)=O)[C@H]1O[C@H](C(COS([O-])(=O)=O)O1)C(O)C(OS([O-])(=O)=O)[C@H]1O[C@H](C(COS([O-])(=O)=O)O1)C(O)C(OS([O-])(=O)=O)[C@H]1O[C@H](C(COS([O-])(=O)=O)O1)C(O)C(OS([O-])(=O)=O)[C@H]1O2 COWYTPMAAISPHT-SWSWVKNJSA-A 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000000536 complexating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Prostheses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/489,680 US5227372A (en) | 1990-03-07 | 1990-03-07 | Method for retaining ophthalmological agents in ocular tissues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE132741T1 true ATE132741T1 (de) | 1996-01-15 |
Family
ID=23944834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91710003T ATE132741T1 (de) | 1990-03-07 | 1991-03-06 | Medikament zum halten ophthalmologischer mittel im augengewebe und verfahren zu seiner herstellung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5227372A (de) |
| EP (1) | EP0447351B1 (de) |
| JP (1) | JPH0729941B2 (de) |
| KR (1) | KR910016315A (de) |
| AT (1) | ATE132741T1 (de) |
| AU (1) | AU636451B2 (de) |
| CA (1) | CA2037624A1 (de) |
| DE (1) | DE69116186D1 (de) |
| IE (1) | IE910658A1 (de) |
| NZ (1) | NZ237165A (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
| US5705178A (en) * | 1991-05-31 | 1998-01-06 | Gliatech, Inc. | Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers |
| WO1993005777A1 (fr) * | 1991-09-18 | 1993-04-01 | Fujisawa Pharmaceutical Co., Ltd. | Preparation transoculaire |
| ATE205092T1 (de) * | 1992-01-30 | 2001-09-15 | Takeda Chemical Industries Ltd | Verfahren zur herstellung hoch-wasserlöslicher zyklodextrinkomplexe |
| TW251236B (de) * | 1992-09-10 | 1995-07-11 | Ciba Vision Ag | |
| US5328930A (en) * | 1993-03-01 | 1994-07-12 | Emory University | Treatment of microsporidial and acanthamoeba keratoconjunctivitis with topical fumagillin |
| US5662919A (en) * | 1994-11-21 | 1997-09-02 | Alcon Laboratories, Inc. | Sulfated polyvinyl alcohol polymers to stabilize pharmaceutical drug compounds |
| US5710148A (en) * | 1995-03-06 | 1998-01-20 | Senju Pharmaceuticals Co., Ltd. | Corneal opacification inhibitory composition |
| US5744154A (en) * | 1995-09-06 | 1998-04-28 | Laboratoire Chauvin S.A. | Ready-to-use indomethacin-based eye lotion |
| US5686095A (en) * | 1995-10-23 | 1997-11-11 | Price, Jr.; Francis W. | Method of treating canker sores |
| DE19539532C2 (de) * | 1995-10-24 | 1999-02-25 | Mann Gerhard Chem Pharm Fab | Ophthalmisches Cromoglicat-Gelpräparat |
| JP2001524097A (ja) * | 1997-04-23 | 2001-11-27 | ユニバーシティ オブ オタゴ | 眼用組成物の制御放出 |
| US20040152664A1 (en) * | 1998-09-02 | 2004-08-05 | Allergan, Inc. | Prednisolone compositions |
| WO2000012137A1 (en) | 1998-09-02 | 2000-03-09 | Allergan Sales, Inc. | Preserved cyclodextrin-containing compositions |
| DE60008234T2 (de) * | 1999-04-29 | 2004-12-30 | Alza Corp., Mountain View | Liposomenzusammensetzungen zur verbesserten wirkstoffzurückhaltung |
| JP2001158750A (ja) * | 1999-12-02 | 2001-06-12 | Lion Corp | 眼科用組成物及び抗アレルギー薬の持続性向上方法 |
| US6265435B1 (en) | 2000-03-07 | 2001-07-24 | Hans Rosenkoetter | Method for enhancing corneal penetration by water soluble ophthalmic drugs |
| RU2177801C1 (ru) * | 2001-01-25 | 2002-01-10 | Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" | Средство, ингибирующее ангиогенез при заболеваниях органа зрения |
| US20040009953A1 (en) * | 2002-01-10 | 2004-01-15 | Comper Wayne D. | Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof |
| US20030181416A1 (en) * | 2002-01-10 | 2003-09-25 | Comper Wayne D. | Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof |
| MXPA04008171A (es) * | 2002-02-22 | 2004-11-26 | Pharmacia Corp | Formulacion oftalmica con sistema de goma. |
| CA2481306A1 (en) * | 2002-04-09 | 2003-10-23 | Greenville Hospital System | Metastasis modulating activity of highly sulfated oligosaccharides |
| US20050085446A1 (en) * | 2003-04-14 | 2005-04-21 | Babu M.K. M. | Fluoroquinolone formulations and methods of making and using the same |
| US20050009782A1 (en) * | 2003-07-09 | 2005-01-13 | Comper Wayne D. | Antiviral charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and methods of use thereof |
| US20050234018A1 (en) * | 2004-04-15 | 2005-10-20 | Allergan, Inc. | Drug delivery to the back of the eye |
| US9125807B2 (en) | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
| ES2667945T3 (es) | 2007-10-08 | 2018-05-16 | Aurinia Pharmaceuticals Inc. | Composiciones oftálmicas que comprenden inhibidores de calcineurina o Inhibidores de mTOR |
| MY156662A (en) * | 2007-11-01 | 2016-03-15 | Acucela Inc | Amine derivative compounds for treating ophthalmic diseases and disorders |
| JP5890182B2 (ja) * | 2009-02-12 | 2016-03-22 | インセプト エルエルシー | ヒドロゲルプラグによる薬物送達 |
| EP2440185B1 (de) * | 2009-06-09 | 2015-04-08 | Aurinia Pharmaceuticals Inc. | Topische arzneimittelabgabesysteme zur ophthalmischen verwendung |
| AU2011233663B2 (en) | 2010-04-03 | 2016-04-14 | Praful Doshi | Medical devices including medicaments and methods of making and using same |
| US10413506B2 (en) | 2010-04-03 | 2019-09-17 | Praful Doshi | Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia |
| US8961501B2 (en) | 2010-09-17 | 2015-02-24 | Incept, Llc | Method for applying flowable hydrogels to a cornea |
| US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
| JP6199883B2 (ja) | 2011-12-05 | 2017-09-20 | インセプト・リミテッド・ライアビリティ・カンパニーＩｎｃｅｐｔ，Ｌｌｃ | 医療用オルガノゲルプロセス及び組成物 |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| ES2777836T3 (es) | 2017-05-17 | 2020-08-06 | Tx Medic Ab | Tratamiento del glaucoma |
| EP3810659A1 (de) * | 2018-06-20 | 2021-04-28 | DuPont Industrial Biosciences USA, LLC | Polysaccharidderivate und zusammensetzungen damit |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2923704A (en) * | 1957-05-15 | 1960-02-02 | Hoffmann La Roche | Cycloamylose sulfates and derivatives thereof |
| US3754925A (en) * | 1970-03-24 | 1973-08-28 | Takeda Chemical Industries Ltd | New thermo gelable polysaccharide containing foodstuffs |
| DK135268A (de) * | 1973-02-09 | |||
| JPS5036422A (de) * | 1973-08-07 | 1975-04-05 | ||
| JPS5366442A (en) * | 1976-11-18 | 1978-06-13 | Takuma Sasaki | Antitumors |
| JPS5583798A (en) * | 1978-12-19 | 1980-06-24 | Takuma Sasaki | (1,3)-beta-d-glucan derivative |
| EP0244178A3 (de) * | 1986-04-28 | 1989-02-08 | Iolab, Inc | Intraokuläre Mittel und Verfahren zu deren Verwendung |
| EP0261719A3 (de) * | 1986-09-23 | 1990-10-10 | Akzo N.V. | Thermochemischlumineszierende Komplexe von Cyclodextrinen |
| JP2577049B2 (ja) * | 1987-06-04 | 1997-01-29 | 三共株式会社 | シクロスポリン製剤 |
| US4877778A (en) * | 1987-07-01 | 1989-10-31 | The Children's Medical Center Corporation | Method of enhancing lipophile transport using cyclodextrin derivatives |
| US4877774A (en) * | 1987-09-09 | 1989-10-31 | The United States Of America As Represented By The Department Of Health And Human Services | Administration of steroid hormones |
| NZ226171A (en) * | 1987-09-18 | 1990-06-26 | Ethicon Inc | Gel formulation containing polypeptide growth factor |
| DE3740838A1 (de) * | 1987-11-27 | 1989-06-08 | Schering Ag | Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel |
| ES2059571T3 (es) * | 1988-01-19 | 1994-11-16 | Takeda Chemical Industries Ltd | Fumagilina como agente angiostatico. |
| KR900700114A (ko) * | 1988-01-19 | 1990-08-11 | 모세 쥬다 포크만 | 성장억제 작용제 및 그 사용법 |
| US5019562A (en) * | 1988-01-19 | 1991-05-28 | The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation | Growth inhibiting agent and the use thereof |
| US5007967A (en) * | 1988-08-15 | 1991-04-16 | American Maize-Products Company | Separation and purification of branched beta cyclodextrins |
-
1990
- 1990-03-07 US US07/489,680 patent/US5227372A/en not_active Expired - Fee Related
-
1991
- 1991-02-20 NZ NZ237165A patent/NZ237165A/xx unknown
- 1991-02-26 AU AU71396/91A patent/AU636451B2/en not_active Ceased
- 1991-02-26 IE IE065891A patent/IE910658A1/en unknown
- 1991-03-06 EP EP91710003A patent/EP0447351B1/de not_active Expired - Lifetime
- 1991-03-06 CA CA002037624A patent/CA2037624A1/en not_active Abandoned
- 1991-03-06 JP JP3040134A patent/JPH0729941B2/ja not_active Expired - Lifetime
- 1991-03-06 DE DE69116186T patent/DE69116186D1/de not_active Expired - Lifetime
- 1991-03-06 AT AT91710003T patent/ATE132741T1/de not_active IP Right Cessation
- 1991-03-07 KR KR1019910003691A patent/KR910016315A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE69116186D1 (de) | 1996-02-22 |
| EP0447351B1 (de) | 1996-01-10 |
| IE910658A1 (en) | 1991-09-11 |
| EP0447351A1 (de) | 1991-09-18 |
| KR910016315A (ko) | 1991-11-05 |
| AU7139691A (en) | 1991-09-12 |
| US5227372A (en) | 1993-07-13 |
| AU636451B2 (en) | 1993-04-29 |
| CA2037624A1 (en) | 1991-09-08 |
| JPH04211615A (ja) | 1992-08-03 |
| NZ237165A (en) | 1992-10-28 |
| JPH0729941B2 (ja) | 1995-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |