ATE135585T1 - Anticoagulatorische zusammensetzung aus laci und sulfatierten polysacchariden - Google Patents

Anticoagulatorische zusammensetzung aus laci und sulfatierten polysacchariden

Info

Publication number: ATE135585T1
Authority: AT; Austria
Prior art keywords: laci; anticoagulatory; composition; sulfated polysaccharides; sulfated
Prior art date: 1990-08-27

Application number

AT91870132T

Other languages

English (en)

Inventor

Tze-Chein Wun

Original Assignee

Monsanto Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-27

Filing date

1991-08-26

Publication date

1996-04-15

1991-08-26 Application filed by Monsanto Co filed Critical Monsanto Co

1996-04-15 Application granted granted Critical

1996-04-15 Publication of ATE135585T1 publication Critical patent/ATE135585T1/de

Links

230000002429 anti-coagulating effect Effects 0.000 title abstract 2
150000004676 glycans Chemical class 0.000 title abstract 2
229920001282 polysaccharide Polymers 0.000 title abstract 2
239000005017 polysaccharide Substances 0.000 title abstract 2
102100030951 Tissue factor pathway inhibitor Human genes 0.000 title 1
101710139626 Tissue factor pathway inhibitor Proteins 0.000 title 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
102000004895 Lipoproteins Human genes 0.000 abstract 1
108090001030 Lipoproteins Proteins 0.000 abstract 1
230000015271 coagulation Effects 0.000 abstract 1
238000005345 coagulation Methods 0.000 abstract 1
-1 heparin Chemical class 0.000 abstract 1
229920000669 heparin Polymers 0.000 abstract 1
229960002897 heparin Drugs 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
230000002195 synergetic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8114—Kunitz type inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Epidemiology (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Diabetes (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT91870132T 1990-08-27 1991-08-26 Anticoagulatorische zusammensetzung aus laci und sulfatierten polysacchariden ATE135585T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US57308390A	1990-08-27	1990-08-27

Publications (1)

Publication Number	Publication Date
ATE135585T1 true ATE135585T1 (de)	1996-04-15

Family

ID=24290576

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91870132T ATE135585T1 (de)	1990-08-27	1991-08-26	Anticoagulatorische zusammensetzung aus laci und sulfatierten polysacchariden

Country Status (10)

Country	Link
EP (1)	EP0473564B1 (de)
JP (1)	JPH0733336B2 (de)
AT (1)	ATE135585T1 (de)
CA (1)	CA2049873C (de)
DE (1)	DE69118056T2 (de)
DK (1)	DK0473564T3 (de)
ES (1)	ES2085462T3 (de)
GR (1)	GR3020312T3 (de)
IE (1)	IE913004A1 (de)
PT (1)	PT98779B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5629287A (en) *	1991-01-18	1997-05-13	University College London	Depot formulations
US5610148A (en) *	1991-01-18	1997-03-11	University College London	Macroscopically oriented cell adhesion protein for wound treatment
US5276015A (en) *	1992-03-18	1994-01-04	Washington University	Method of inhibiting microvascular thrombosis
US6063764A (en) *	1992-06-01	2000-05-16	Washington University & Chiron Corp.	Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US20030171292A1 (en)	1992-06-01	2003-09-11	Creasey Abla A.	Method for using lipoprotein associated coagulation inhibitor to treat sepsis
ITPD940054A1 (it) *	1994-03-23	1995-09-23	Fidia Advanced Biopolymers Srl	Polisaccaridi solfatati
DK0769962T3 (da) *	1994-07-07	2003-06-23	Univ Washington	Fremgangsmåde til afsvækkelse af arteriel stenose
US5589359A (en)	1994-08-05	1996-12-31	Chiron Corporation	Chimeric proteins
WO1996004377A1 (en) *	1994-08-05	1996-02-15	Chiron Corporation	Production of tissue factor pathway inhibitor
AU759412B2 (en) *	1995-06-07	2003-04-17	G.D. Searle & Co.	Method of solubilizing, purifying and refolding protein and compositions comprising proteins and solubilizing agents
AU2003200506B2 (en) *	1995-06-07	2007-01-18	G.D. Searle Llc	Method of solubilizing, purifying and refolding protein and compositions comprising proteins and solubilizing agents
ATE301675T1 (de) *	1995-06-07	2005-08-15	Chiron Corp	Methode zur lösung, reinigung und rückfaltung von protein
US5772629A (en) *	1995-10-23	1998-06-30	Localmed, Inc.	Localized intravascular delivery of TFPI for inhibition of restenosis in recanalized blood vessels
EP0868191A1 (de) *	1995-12-18	1998-10-07	Stichting Sanquin Bloedvoorziening	Potenzierung der komplement und gerinnungsinhibierenden eigenschaften von c1-inaktivator
US7674769B2 (en)	2001-10-15	2010-03-09	Novartis Vaccines And Diagnostics, Inc.	Treatment of severe pneumonia by administration of tissue factor pathway inhibitor (TFPI)
EP1654283B1 (de)	2003-08-13	2011-07-13	Novartis Vaccines and Diagnostics, Inc.	Verbessertes verfahren zur reinigung von tfpi und tfpi-analogen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL87172A (en) *	1987-07-23	1994-12-29	Univ Washington	Method of isolating highly purified tissue factor inhibitor
IL87171A (en) *	1987-11-23	1995-08-31	Monsanto Co	cDNA of human tissue factor inhibitor
DE69117545T2 (de) *	1990-01-25	1996-10-31	Univ Washington	Faktor X-LACI-Hybridprotein

1991
- 1991-08-26 AT AT91870132T patent/ATE135585T1/de not_active IP Right Cessation
- 1991-08-26 IE IE300491A patent/IE913004A1/en not_active IP Right Cessation
- 1991-08-26 ES ES91870132T patent/ES2085462T3/es not_active Expired - Lifetime
- 1991-08-26 PT PT98779A patent/PT98779B/pt not_active IP Right Cessation
- 1991-08-26 CA CA002049873A patent/CA2049873C/en not_active Expired - Lifetime
- 1991-08-26 JP JP3213844A patent/JPH0733336B2/ja not_active Expired - Fee Related
- 1991-08-26 EP EP91870132A patent/EP0473564B1/de not_active Expired - Lifetime
- 1991-08-26 DE DE69118056T patent/DE69118056T2/de not_active Expired - Lifetime
- 1991-08-26 DK DK91870132.7T patent/DK0473564T3/da active
1996
- 1996-06-20 GR GR960401682T patent/GR3020312T3/el unknown

Also Published As

Publication number	Publication date
PT98779A (pt)	1992-07-31
JPH0733336B2 (ja)	1995-04-12
EP0473564A1 (de)	1992-03-04
GR3020312T3 (en)	1996-09-30
PT98779B (pt)	1999-06-30
DK0473564T3 (da)	1996-04-15
CA2049873A1 (en)	1992-02-28
EP0473564B1 (de)	1996-03-20
DE69118056T2 (de)	1996-10-24
JPH04257524A (ja)	1992-09-11
IE913004A1 (en)	1992-03-11
ES2085462T3 (es)	1996-06-01
DE69118056D1 (de)	1996-04-25
CA2049873C (en)	2001-12-04

Similar Documents

Publication	Publication Date	Title
ATE135585T1 (de)	1996-04-15	Anticoagulatorische zusammensetzung aus laci und sulfatierten polysacchariden
AU5841090A (en)	1991-01-08	Sulphated polysaccharides, anticoagulant agent and anticomplementary agent obtained from brown algae fucuses and method of obtaining same
MD1224C2 (ro)	1999-11-30	Utilizare a analogilor nucleozidici cu 1,3-oxatiolan în tratamentul hepatitei B
ES2102131T3 (es)	1997-07-16	Elastomeros termoplasticos fluorados que tienen superiores propiedades mecanicas y elasticas.
ES2059296T3 (es)	1996-07-16	Inhibidores de proteasas retrovirales.
DK0793674T3 (da)	2000-08-14	Inhibitorer af human neutrofil elastase
DE69533472D1 (de)	2004-10-14	Kallikreinhemmende "kunitz-domäne"-proteine und derivaten davon
AU2406402A (en)	2002-06-03	Substituted benzene derivatives or salts thereof
DK1284740T3 (da)	2008-08-04	Profylaktisk og terapeutisk behandling af infektiöse sygdomme, autoimmunsygdomme og allergiske sygdomme med monosaccharidbaserede forbindelser
DK0605293T3 (da)	1998-04-14	Polymersammensætninger med lav gulningsgrad, polymeriserbare sammensætninger og deraf fremstillede linser
NO1999018I1 (no)	1999-07-22	Lamivudin og zidovudin
NO942551D0 (no)	1994-07-06	Humanproteaseinhibitorvariant av Kunitz-type
MD306B1 (ro)	1995-10-31	Remediu pentru profilaxia afectiunilor vasculare determinate de actiunea peroxizilor glicoproteinfixati
ATE143810T1 (de)	1996-10-15	Hepatozytwachstumsfaktor enthaltende mittel
DE69100865D1 (de)	1994-02-10	1,4,8-Triazacyclotridecan-Derivate mit Prolylendopeptidase-hemmender Wirkung.
NO872675L (no)	1987-12-28	Middel for hemning av avstoetning av transplanterte organer
DK0424351T3 (da)	1997-10-13	Anvendelse af modificeret heparin-cofaktor II
ATE108801T1 (de)	1994-08-15	Antikoagulierende peptid-alkohole.
ATE92325T1 (de)	1993-08-15	Kombinationspraeparat mit antithrombotischer wirkung.
DK0458589T3 (da)	1995-04-03	Behandling af okulær hypertension med en okulær synergistisk kombination
ATE106763T1 (de)	1994-06-15	Schi.
PT666755E (pt)	2003-09-30	Inibicao da infeccao pelo vih
DK0427402T3 (da)	1993-08-16	Anvendelse af cyclodextriner og derivater deraf
CA2060333A1 (en)	1992-08-02	Use of pyrimido-benzothiazine derivatives
DE69003342D1 (de)	1993-10-21	Pharmazeutische Zusammensetzungen.

Legal Events

Date	Code	Title	Description
2011-05-15	REN	Ceased due to non-payment of the annual fee