ATE138059T1 - 3-aryloxazolidinonderivate, verfahren zu ihrer herstellung und ihre anwendung in der heilkunde - Google Patents

3-aryloxazolidinonderivate, verfahren zu ihrer herstellung und ihre anwendung in der heilkunde

Info

Publication number: ATE138059T1
Authority: AT; Austria
Prior art keywords: derivatives; denotes; alkyl; forms; group
Prior art date: 1991-04-16

Application number

AT92400721T

Other languages

English (en)

Inventor

Francois-Xavier Jarreau

Jean-Jacques Koenig

Vincenzo Rovei

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-16

Filing date

1992-03-18

Publication date

1996-06-15

1992-03-18 Application filed by Synthelabo filed Critical Synthelabo

1996-06-15 Application granted granted Critical

1996-06-15 Publication of ATE138059T1 publication Critical patent/ATE138059T1/de

Links

125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
125000000815 N-oxide group Chemical group 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
125000002112 pyrrolidino group Chemical group [*]N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

AT92400721T 1991-04-16 1992-03-18 3-aryloxazolidinonderivate, verfahren zu ihrer herstellung und ihre anwendung in der heilkunde ATE138059T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9104641A FR2675504B1 (fr)	1991-04-16	1991-04-16	Derives d'aryl-3 oxazolidinone, leur procede de preparation et leur application en therapeutique.

Publications (1)

Publication Number	Publication Date
ATE138059T1 true ATE138059T1 (de)	1996-06-15

Family

ID=9411887

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92400721T ATE138059T1 (de)	1991-04-16	1992-03-18	3-aryloxazolidinonderivate, verfahren zu ihrer herstellung und ihre anwendung in der heilkunde

Country Status (13)

Country	Link
US (1)	US5264443A (de)
EP (1)	EP0511031B1 (de)
JP (1)	JPH05112542A (de)
KR (1)	KR920019766A (de)
AT (1)	ATE138059T1 (de)
AU (1)	AU647909B2 (de)
CA (1)	CA2065962A1 (de)
DE (1)	DE69210675T2 (de)
DK (1)	DK0511031T3 (de)
ES (1)	ES2087474T3 (de)
FR (1)	FR2675504B1 (de)
GR (1)	GR3020546T3 (de)
NZ (1)	NZ242351A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH06510285A (ja) *	1991-08-14	1994-11-17	プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド	抗不整脈及び抗細動剤として有用な環状ウレタン類
TW286317B (de) *	1993-12-13	1996-09-21	Hoffmann La Roche
FR2715155B1 (fr) *	1994-01-19	1996-07-26	Mayoly Spindler	Inhibiteurs de la monoamine oxydase B et leurs procédés de préparation.
ATE170179T1 (de)	1994-11-02	1998-09-15	Merck Patent Gmbh	Adhäsionsrezeptor-antagonisten
US6455554B1 (en)	1999-06-07	2002-09-24	Targacept, Inc.	Oxopyridinyl pharmaceutical compositions and methods for use
CN1798557A (zh) *	2003-05-29	2006-07-05	协和梅迪克斯株式会社	抗抑郁剂或者抗抑郁用饮食品
AU2009271302A1 (en) *	2008-06-24	2010-01-21	Valeant Pharmaceuticals International	Benzyloxy anilide derivatives useful as potassium channel modulators
GB2571696B (en)	2017-10-09	2020-05-27	Compass Pathways Ltd	Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US12459965B2 (en)	2017-10-09	2025-11-04	Compass Pathfinder Limited	Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US12377112B2 (en)	2019-04-17	2025-08-05	Compass Pathfinder Limited	Methods of treating neurocognitive disorders, chronic pain and reducing inflammation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2954381A (en) *	1958-12-03	1960-09-27	Us Vitamin Pharm Corp	Heteroaryloxazolidinediones
US3290326A (en) *	1963-09-20	1966-12-06	Hoffmann La Roche	Esters of 4-lower alkyl-5-oxazole-car-bamic acid and intermediates therefor
US4133675A (en) *	1976-07-23	1979-01-09	Ciba-Geigy Corporation	Pyridyloxy-phenoxy-alkanecarboxylic acid derivatives which are effective as herbicides and as agents regulating plant growth
FR2506769A2 (fr) *	1978-06-09	1982-12-03	Delalande Sa	Para-((cyano-5 n pentyl-1) phenyl)-3 methoxymethyl-5 oxazolidinone-2, son procede de preparation et ses applications en therapeutique
US4348393A (en) *	1978-06-09	1982-09-07	Delalande S.A.	N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones
CA1171865A (en) *	1980-06-04	1984-07-31	Alain Lacour	N-aryl azolone derivatives, the process for preparing the same and their application in therapeutics
FR2608604B1 (fr) *	1986-12-19	1989-04-28	Delalande Sa	Derives 5-hydroxyethyles de l'oxazolidinone-2, leurs procedes de preparation et leurs applications en therapeutique
FR2653017B1 (fr) *	1989-10-17	1995-05-05	Delalande Sa	Derives d'aryl-3 oxazolidinone-2, leur procede de preparation et leur application en therapeutique.

1991
- 1991-04-16 FR FR9104641A patent/FR2675504B1/fr not_active Expired - Fee Related
1992
- 1992-03-18 DE DE69210675T patent/DE69210675T2/de not_active Expired - Fee Related
- 1992-03-18 AT AT92400721T patent/ATE138059T1/de not_active IP Right Cessation
- 1992-03-18 DK DK92400721.4T patent/DK0511031T3/da active
- 1992-03-18 EP EP92400721A patent/EP0511031B1/de not_active Expired - Lifetime
- 1992-03-18 ES ES92400721T patent/ES2087474T3/es not_active Expired - Lifetime
- 1992-04-08 KR KR1019920005842A patent/KR920019766A/ko not_active Ceased
- 1992-04-09 US US07/865,885 patent/US5264443A/en not_active Expired - Fee Related
- 1992-04-14 NZ NZ242351A patent/NZ242351A/xx unknown
- 1992-04-14 CA CA002065962A patent/CA2065962A1/en not_active Abandoned
- 1992-04-15 AU AU14910/92A patent/AU647909B2/en not_active Ceased
- 1992-04-15 JP JP4095189A patent/JPH05112542A/ja active Pending
1996
- 1996-07-16 GR GR960401914T patent/GR3020546T3/el unknown

Also Published As

Publication number	Publication date
JPH05112542A (ja)	1993-05-07
EP0511031A1 (de)	1992-10-28
AU647909B2 (en)	1994-03-31
ES2087474T3 (es)	1996-07-16
EP0511031B1 (de)	1996-05-15
CA2065962A1 (en)	1992-10-17
FR2675504B1 (fr)	1995-01-27
DK0511031T3 (da)	1996-09-30
KR920019766A (ko)	1992-11-19
US5264443A (en)	1993-11-23
DE69210675D1 (de)	1996-06-20
GR3020546T3 (en)	1996-10-31
AU1491092A (en)	1992-10-22
DE69210675T2 (de)	1996-11-28
NZ242351A (en)	1993-08-26
FR2675504A1 (fr)	1992-10-23

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Legal Events

Date	Code	Title	Description
1997-01-15	UEP	Publication of translation of european patent specification
1998-12-15	REN	Ceased due to non-payment of the annual fee