DK0609643T3 - Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration - Google Patents

Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration

Info

Publication number
DK0609643T3
DK0609643T3 DK93830506.7T DK93830506T DK0609643T3 DK 0609643 T3 DK0609643 T3 DK 0609643T3 DK 93830506 T DK93830506 T DK 93830506T DK 0609643 T3 DK0609643 T3 DK 0609643T3
Authority
DK
Denmark
Prior art keywords
carnitine
preparing
waste product
opposite configuration
lactone
Prior art date
Application number
DK93830506.7T
Other languages
Danish (da)
English (en)
Inventor
Fabio Giannessi
Maria Ornella Tinti
Maria Laura Bolognesi
Francesco De Angelis
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK0609643T3 publication Critical patent/DK0609643T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12—Beta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Processing Of Solid Wastes (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK93830506.7T 1992-12-21 1993-12-15 Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration DK0609643T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920915A IT1256705B (it) 1992-12-21 1992-12-21 Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.

Publications (1)

Publication Number Publication Date
DK0609643T3 true DK0609643T3 (da) 1996-11-11

Family

ID=11401346

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93830506.7T DK0609643T3 (da) 1992-12-21 1993-12-15 Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration

Country Status (13)

Country Link
US (2) US5412113A (de)
EP (1) EP0609643B1 (de)
JP (1) JP3502649B2 (de)
KR (1) KR100294780B1 (de)
AT (1) ATE140694T1 (de)
CA (1) CA2111898C (de)
DE (1) DE69303807T2 (de)
DK (1) DK0609643T3 (de)
ES (1) ES2090945T3 (de)
GR (1) GR3020617T3 (de)
HK (1) HK1005861A1 (de)
IT (1) IT1256705B (de)
ZA (1) ZA939444B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1240760B (it) * 1990-02-12 1993-12-17 Sigma Tau Ind Farmaceuti Esteri di acil-l-carnitine con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che li contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma.
IT1261230B (it) * 1993-04-08 1996-05-09 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione.
IT1261828B (it) 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
IT1276207B1 (it) * 1995-09-29 1997-10-27 Sigma Tau Ind Farmaceuti Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone
IT1277953B1 (it) * 1995-12-21 1997-11-12 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per
IT1297120B1 (it) * 1997-12-16 1999-08-03 Sigma Tau Ind Farmaceuti Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina
IT1299182B1 (it) 1998-05-29 2000-02-29 Sigma Tau Ind Farmaceuti Procedimento chimico per la sintesi stereoselettiva della r-(-)- carnitina.
IT1301977B1 (it) * 1998-07-31 2000-07-20 Sigma Tau Ind Farmaceuti Procedimento per la preparazione di r-(-)-carnitina
IT1307303B1 (it) 1999-12-23 2001-10-30 Sigma Tau Ind Farmaceuti Idrolisi stereospecifica di esteri otticamente attivi.
IT1306184B1 (it) * 1999-08-05 2001-05-30 Sigma Tau Ind Farmaceuti Nitrilossi derivati della (r) e (s)-carnitina.
WO2001017525A1 (en) * 1999-09-03 2001-03-15 Sigma-Tau Healthscuience S.P.A Ultrafine l-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same
DE10027393B4 (de) * 2000-06-02 2007-05-16 Wella Ag Poly- und Oligoester kationischer Hydroxysäuren, Verfahren zu ihrer Herstellung und ihre Verwendung
JP6034287B2 (ja) * 2010-07-21 2016-11-30 ロンザ リミテッドＬｏｎｚａ Ｌｉｍｉｔｅｄ β−ラクトンからのカルニチンの製造のためのプロセス
SMT202300445T1 (it) 2014-07-03 2024-03-13 Silti Ag Metodi e composizioni per trattare l’obesità, prevenire l’aumento di peso, promuovere la perdita di peso, promuovere il dimagrimento, o trattare o prevenire lo sviluppo del diabete
CN115057789B (zh) * 2022-06-30 2024-04-02 中科萱嘉医养(珠海)健康科技有限公司 一种左旋肉碱离子液体及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3830931A (en) 1972-11-06 1974-08-20 Felice S De Carnitine and its use in the treatment of arrhythmia and impaired cardiac function
IT1156852B (it) * 1978-07-10 1987-02-04 Sigma Tau Ind Farmaceuti Procedimento industriale per la preparazione del d'canforato della l carnitinammide e del d canforato della d carnitinammide e sue applicazioni
IT1136945B (it) * 1981-03-18 1986-09-03 Anic Spa Processo per la preparazione di l-carnitina
US5200526A (en) * 1987-04-27 1993-04-06 The Governors Of The University Of Alberta Syntheses of optically pure α-amino acids from 3-amino-2-oxetanone salts

Also Published As

Publication number Publication date
ITRM920915A0 (it) 1992-12-21
JP3502649B2 (ja) 2004-03-02
JPH06199751A (ja) 1994-07-19
IT1256705B (it) 1995-12-12
ZA939444B (en) 1994-08-09
KR940014303A (ko) 1994-07-18
ES2090945T3 (es) 1996-10-16
EP0609643B1 (de) 1996-07-24
US5412113A (en) 1995-05-02
US5599978A (en) 1997-02-04
CA2111898C (en) 2004-04-27
KR100294780B1 (ko) 2001-09-17
CA2111898A1 (en) 1994-06-22
EP0609643A1 (de) 1994-08-10
GR3020617T3 (en) 1996-10-31
DE69303807T2 (de) 1996-11-28
HK1005861A1 (en) 1999-01-29
DE69303807D1 (de) 1996-08-29
ATE140694T1 (de) 1996-08-15
ITRM920915A1 (it) 1994-06-21

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