ATE141168T1 - Zubereitung für die herstellung von hepatitis b virus-oberflächenantigen und polymerisierten humanserumalbuminrezeptor tragende partikel enthaltenden vakzinen, tierische zellen für die herstellung von diesen partikeln und verfahren für ihre erhaltung - Google Patents

Zubereitung für die herstellung von hepatitis b virus-oberflächenantigen und polymerisierten humanserumalbuminrezeptor tragende partikel enthaltenden vakzinen, tierische zellen für die herstellung von diesen partikeln und verfahren für ihre erhaltung

Info

Publication number
ATE141168T1
ATE141168T1 AT85400444T AT85400444T ATE141168T1 AT E141168 T1 ATE141168 T1 AT E141168T1 AT 85400444 T AT85400444 T AT 85400444T AT 85400444 T AT85400444 T AT 85400444T AT E141168 T1 ATE141168 T1 AT E141168T1
Authority
AT
Austria
Prior art keywords
particles
production
hepatitis
receptor
surface antigen
Prior art date
Application number
AT85400444T
Other languages
English (en)
Inventor
Eliane Sobczak
Yves Malpiece
Marie-Louise Michel
Pierre Tiollais
Rolf E Streeck
Original Assignee
Pasteur Institut
Inst Nat Sante Rech Med
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut, Inst Nat Sante Rech Med, Centre Nat Rech Scient filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE141168T1 publication Critical patent/ATE141168T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AT85400444T 1984-03-07 1985-03-07 Zubereitung für die herstellung von hepatitis b virus-oberflächenantigen und polymerisierten humanserumalbuminrezeptor tragende partikel enthaltenden vakzinen, tierische zellen für die herstellung von diesen partikeln und verfahren für ihre erhaltung ATE141168T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8403564A FR2560890B1 (fr) 1984-03-07 1984-03-07 Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention

Publications (1)

Publication Number Publication Date
ATE141168T1 true ATE141168T1 (de) 1996-08-15

Family

ID=9301807

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85400444T ATE141168T1 (de) 1984-03-07 1985-03-07 Zubereitung für die herstellung von hepatitis b virus-oberflächenantigen und polymerisierten humanserumalbuminrezeptor tragende partikel enthaltenden vakzinen, tierische zellen für die herstellung von diesen partikeln und verfahren für ihre erhaltung

Country Status (10)

Country Link
EP (2) EP0732104A1 (de)
JP (1) JPH08839B2 (de)
KR (1) KR930003609B1 (de)
AT (1) ATE141168T1 (de)
AU (1) AU598181B2 (de)
CA (1) CA1262532A (de)
DE (1) DE3588117T2 (de)
FR (1) FR2560890B1 (de)
SU (1) SU1625332A3 (de)
WO (1) WO1985003876A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL79740A0 (en) * 1986-08-17 1986-11-30 Yeda Res & Dev Hepatitis vaccine
FR2608052B1 (fr) * 1986-12-10 1990-04-13 Pasteur Vaccins Procede de preparation d'un vaccin contre l'hepatite b et vaccin obtenu
EP1088830A3 (de) * 1987-06-22 2004-04-07 Medeva Holdings B.V. Partikel von Hepatitis B Oberflächenantigen
CA1341074C (en) * 1987-06-22 2000-08-08 Hans A. Thoma Hbv surface antigen particles, prepared by recombinant dna processes, composed of different epitopes, selected from the pre-s and s-peptides as a new vaccine
WO1988010301A1 (en) * 1987-06-22 1988-12-29 Mccormick And Jones Engineering Ltd. Hepatitis b surface antigen vaccine
JPH0216975A (ja) * 1988-02-09 1990-01-19 Eugene Tech Internatl Inc 異成分混交性のプレーｓに富んだｂ型肝炎表面抗原
EP0491077A1 (de) * 1990-12-19 1992-06-24 Medeva Holdings B.V. Zusammensetzung verwendbar als therapeutisches Mittel gegen chronische virale Leberkrankheiten
FR2711670B1 (fr) 1993-10-22 1996-01-12 Pasteur Institut Vecteur nucléotidique, composition le contenant et vaccin pour l'immunisation à l'encontre d'une hépatite.
RU2135209C1 (ru) * 1998-07-17 1999-08-27 Акционерное общество закрытого типа НПК "Комбиотех Лтд" Фармацевтическая композиция для иммунопрофилактики вирусного гепатита b
JP4085231B2 (ja) * 2000-02-28 2008-05-14 株式会社ビークル タンパク質中空ナノ粒子とそれを用いた物質運搬体、ならびに細胞への物質導入方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4113712A (en) * 1976-03-08 1978-09-12 The Green Cross Corporation HBsAG Particle composed of single polypeptide subunits and the preparation procedure
CA1100037A (en) * 1977-03-11 1981-04-28 Chung-Mei Ling Hb.sub.c ag coated on solid phase
IE53176B1 (en) * 1978-12-22 1988-08-17 Biogen Nv Recombinant dna molecules and their method of production
JPS5610119A (en) * 1979-07-05 1981-02-02 Alpha Therapeutic Corp Manufacture of b type hepatitis infection preventive vaccine
FR2480780B1 (fr) * 1980-04-22 1985-12-06 Pasteur Institut Procede de transformation de cellules, notamment eucaryotes, par un adn circulaire tel que celui du virus de l'hepatite b et preparations contenant les produits d'expression desdits adn
DE3176404D1 (en) * 1980-04-22 1987-10-08 Pasteur Institut Vaccine against viral hepatitis b, method and transformed eucaryotic cells for the preparation of this vaccine
ZW18282A1 (en) * 1981-08-31 1983-03-23 Genentech Inc Preparation of polypeptides in vertebrate cell culture
JPS5936698A (ja) * 1982-08-20 1984-02-28 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えｄｎａおよび形質転換動物細胞
US4847080A (en) * 1984-03-07 1989-07-11 New York Blood Center, Inc. Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipide vesicle carriers
WO1985004103A1 (en) * 1984-03-09 1985-09-26 Scripps Clinic And Research Foundation Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants
NL8401066A (nl) * 1984-04-04 1985-11-01 Stichting Centraal Lab Werkwijze ter bereiding van preparaten, die de humorale en cellulaire immuunreaktiviteit vergroten.

Also Published As

Publication number Publication date
WO1985003876A1 (fr) 1985-09-12
DE3588117D1 (de) 1996-09-19
JPH08839B2 (ja) 1996-01-10
JPS61500971A (ja) 1986-05-15
AU4061085A (en) 1985-09-24
EP0156712A1 (de) 1985-10-02
FR2560890A1 (fr) 1985-09-13
EP0156712B1 (de) 1996-08-14
EP0732104A1 (de) 1996-09-18
KR850700214A (ko) 1985-12-26
KR930003609B1 (ko) 1993-05-08
AU598181B2 (en) 1990-06-21
FR2560890B1 (fr) 1987-10-16
CA1262532A (fr) 1989-10-31
SU1625332A3 (ru) 1991-01-30
DE3588117T2 (de) 1997-03-20

Similar Documents

Publication Publication Date Title
DE69019609D1 (de) Proteine und deren Herstellung.
ATE141168T1 (de) Zubereitung für die herstellung von hepatitis b virus-oberflächenantigen und polymerisierten humanserumalbuminrezeptor tragende partikel enthaltenden vakzinen, tierische zellen für die herstellung von diesen partikeln und verfahren für ihre erhaltung
FI102075B1 (fi) Menetelmä valmistaa glykosyloitu tai glykosyloimaton polypeptidi, rekombinanttinukleiinihappo ja vektorit
DE3584866D1 (de) Hybridpartikel-immunogene.
NO903285L (no) Nye antigener og fremstilling derav.
PT82500B (pt) Particulas com as propriedades imunogenicas do antigenio hbs e portadoras de um sitio antigenico estranho aos epitopes comportados pelo antigenio hbs, vectores e celulas animais para a producao dessas particulas e composicoes que contem essas particulas para a producao de vacinas mistas
ATE62254T1 (de) Multispezifische immunogene proteine.
DE59010450D1 (de) Toxoplasma gondii-Antigene, ihre Herstellung und ihre Verwendung
ES532730A0 (es) Un procedimiento para preparar el antigeno de superficie de la hepatitis b
ATE122568T1 (de) Polypeptide, antigene oder vakzine gegen babesiosis.
ATE73349T1 (de) Hepatitisoberflaechenantigenpartikelvakzin.
EP0062574A3 (de) Synthese von Virusproteinen
ATE102650T1 (de) Mutanten des infektioesen bovinen rhinotracheitisvirus, vakzine die sie enthalten, verfahren zu ihrer herstellung und ihrer verwendung.
PT84976A (pt) Method of producing feline leukemia virus antigens containing recombinant polypeptides
Zuckerman et al. Toward hepatitis B vaccines
TH1016A (th) การประดิษฐ์และการใช้กรดดีออกซีไรโบนิวคลีอิค(กรรมวิธี)
Thibodeau et al. Immunosome technology: An approach to efficient and safe influenza and rabies vaccines.
IT1165451B (it) Virus vaccinico modificato e metodi per la produzione ed uso del medesimo
ATE53235T1 (de) Synthese von menschlichen viralen antigenen mit hilfe von hefe.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time