ATE198750T1 - Isatinoxim-derivate, ihre herstellung und verwendung - Google Patents

Isatinoxim-derivate, ihre herstellung und verwendung

Info

Publication number: ATE198750T1
Authority: AT; Austria
Prior art keywords: alkyl; hydrogen; isatinoxim; derivatives; preparation
Prior art date: 1993-07-07

Application number

AT94610036T

Other languages

English (en)

Inventor

Frank Waetjen

Bjarne Hugo Dahl

Jorgen Drejer

Leif Helth Jensen

Original Assignee

Neurosearch As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-07

Filing date

1994-06-29

Publication date

2001-02-15

1994-06-29 Application filed by Neurosearch As filed Critical Neurosearch As

2001-02-15 Application granted granted Critical

2001-02-15 Publication of ATE198750T1 publication Critical patent/ATE198750T1/de

Links

NGXLTYPELAIUHE-UHFFFAOYSA-N 2-(hydroxyamino)indol-3-one Chemical class C1=CC=C2C(=O)C(NO)=NC2=C1 NGXLTYPELAIUHE-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
150000002431 hydrogen Chemical class 0.000 abstract 2
OZDAOHVKBFBBMZ-UHFFFAOYSA-N 2-aminopentanedioic acid;hydrate Chemical compound O.OC(=O)C(N)CCC(O)=O OZDAOHVKBFBBMZ-UHFFFAOYSA-N 0.000 abstract 1
WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
108010011562 aspartic acid receptor Proteins 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
235000013922 glutamic acid Nutrition 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT94610036T 1993-07-07 1994-06-29 Isatinoxim-derivate, ihre herstellung und verwendung ATE198750T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK93815A DK81593D0 (da)	1993-07-07	1993-07-07	Nye isatinoximderivater, deres fremstilling og anvendelse

Publications (1)

Publication Number	Publication Date
ATE198750T1 true ATE198750T1 (de)	2001-02-15

Family

ID=8097883

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94610036T ATE198750T1 (de)	1993-07-07	1994-06-29	Isatinoxim-derivate, ihre herstellung und verwendung

Country Status (4)

Country	Link
EP (1)	EP0633262B1 (de)
AT (1)	ATE198750T1 (de)
DE (1)	DE69426581T2 (de)
DK (2)	DK81593D0 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA54403C2 (uk) *	1996-10-01	2003-03-17	Н'Юросерч А/С	Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму
ATE420636T1 (de)	1999-05-19	2009-01-15	Painceptor Pharma Corp	Hemmer der protonenabhängigen kationenkanäle und deren verwendung in der behandlung von ischemiebedingten erkrankungen
CN101346375B (zh)	2005-11-23	2013-04-10	阿罗斯药物有限责任公司	调节门离子通道用组合物和方法
CA2652307A1 (en) *	2006-04-10	2007-10-18	Painceptor Pharma Corporation	Compositions and methods for modulating gated ion channels

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU655643B2 (en) *	1991-07-09	1995-01-05	Neurosearch A/S	Novel isatineoxime derivatives, their preparation and use
MX9204914A (es) *	1991-08-28	1993-07-01	Frank Watjen	Nuevos derivados de isatinoxima, metodo para su preparacion y composicion farmaceutica que los comprende.

1993
- 1993-07-07 DK DK93815A patent/DK81593D0/da not_active Application Discontinuation
1994
- 1994-06-29 EP EP94610036A patent/EP0633262B1/de not_active Expired - Lifetime
- 1994-06-29 DK DK94610036T patent/DK0633262T3/da active
- 1994-06-29 DE DE69426581T patent/DE69426581T2/de not_active Expired - Lifetime
- 1994-06-29 AT AT94610036T patent/ATE198750T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0633262B1 (de)	2001-01-17
DK0633262T3 (da)	2001-04-23
EP0633262A1 (de)	1995-01-11
DE69426581D1 (de)	2001-02-22
DE69426581T2 (de)	2001-06-21
DK81593D0 (da)	1993-07-07

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Legal Events

Date	Code	Title	Description
2001-05-15	UEP	Publication of translation of european patent specification
2004-03-15	REN	Ceased due to non-payment of the annual fee