ATE146219T1 - Polypeptid - Google Patents

Polypeptid

Info

Publication number
ATE146219T1
ATE146219T1 AT90914512T AT90914512T ATE146219T1 AT E146219 T1 ATE146219 T1 AT E146219T1 AT 90914512 T AT90914512 T AT 90914512T AT 90914512 T AT90914512 T AT 90914512T AT E146219 T1 ATE146219 T1 AT E146219T1
Authority
AT
Austria
Prior art keywords
sod
variants
pct
recombinant
amino acid
Prior art date
Application number
AT90914512T
Other languages
English (en)
Inventor
Stefan Marklund
Thomas Edlund
Original Assignee
Symbicom Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbicom Ab filed Critical Symbicom Ab
Application granted granted Critical
Publication of ATE146219T1 publication Critical patent/ATE146219T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
AT90914512T 1989-09-15 1990-09-17 Polypeptid ATE146219T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK455789A DK455789D0 (da) 1989-09-15 1989-09-15 Polypeptid

Publications (1)

Publication Number Publication Date
ATE146219T1 true ATE146219T1 (de) 1996-12-15

Family

ID=8134617

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90914512T ATE146219T1 (de) 1989-09-15 1990-09-17 Polypeptid

Country Status (7)

Country Link
US (1) US5366729A (de)
EP (1) EP0593435B1 (de)
AT (1) ATE146219T1 (de)
AU (1) AU6444190A (de)
DE (1) DE69029406D1 (de)
DK (1) DK455789D0 (de)
WO (1) WO1991004315A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843641A (en) 1993-02-26 1998-12-01 Massachusetts Institute Of Technology Methods for the daignosis, of familial amyotrophic lateral sclerosis
EP0627486A1 (de) * 1993-06-04 1994-12-07 N.V. Innogenetics S.A. Extra zellulare Superoxyd-Dismutase, Verfahren zur deren Herstellung und diese enthaltende Zusammensetzungen
DK75393D0 (da) * 1993-06-24 1993-06-24 Symbicom Ab Production of protein
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US5747026A (en) * 1993-10-15 1998-05-05 University Of Alabama At Birmingham Research Foundation Antioxidants
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
WO1996009053A1 (en) * 1994-09-20 1996-03-28 Duke University Oxidoreductase activity of manganic porphyrins
JPH08208511A (ja) * 1995-01-31 1996-08-13 Samu Kenkyusho:Kk 抗運動ニューロン疾患剤
JPH11509180A (ja) * 1995-06-07 1999-08-17 デューク・ユニバーシティ 酸化体脱除剤
AU769217B2 (en) * 1995-06-07 2004-01-22 Duke University Oxidant scavengers
JP2001521939A (ja) 1997-11-03 2001-11-13 デューク・ユニバーシティー 置換されたポルフィリン類
DE69928655T2 (de) 1998-04-24 2006-08-24 Duke University Substituierte porphyrine
US6190658B1 (en) 1998-05-08 2001-02-20 Webb-Waring Institute For Biomedical Research Genetically modified manganese superoxide dismutase for treating oxidative damage
EP1155019B1 (de) 1999-01-25 2005-12-07 National Jewish Medical and Research Center Substituierte porphyrine und deren therapeutische verwendungen
US8003595B2 (en) 2000-03-01 2011-08-23 Cellectis Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei
FR2805821B1 (fr) * 2000-03-01 2004-01-16 Diatos Sequences d'acides amines facilitant la penetration d'une substance d'interet a l'interieur des cellules et/ou des noyaux cellulaires
JP2004520380A (ja) * 2001-01-19 2004-07-08 ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター 癌治療本出願は、２００１年１月１９日に出願の仮出願番号第６０／２６２，３９０号の優先権を主張し、その全ての内容は、参照により本願明細書に援用したものとする。
FI20010898A0 (fi) * 2001-04-30 2001-04-30 Ylae Herttuala Seppo Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi
FI116851B (fi) * 2001-05-03 2006-03-15 Fit Biotech Oyj Plc Ilmentämisvektori, sen käyttöjä ja menetelmä sen valmistamiseksi sekä sitä sisältäviä tuotteita
JP2005508864A (ja) * 2001-06-01 2005-04-07 ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター 糖尿病の治療、または移植術における使用、または免疫寛容の誘導のためのオキシダントスカベンジャー
US20030027745A1 (en) * 2001-06-13 2003-02-06 Repine John E. Diagnostic and prognostic method for evaluating ocular inflammation and oxidative stress and the treatment of the same
EP1513537A4 (de) * 2002-06-07 2006-09-06 Univ Duke Substituierte porphyrine
BRPI0413521A (pt) 2003-08-14 2006-10-10 Diatos seqüências de aminoácidos que facilitam a penetração de uma substáncia de interesse nas células e/ou no núcleos celulares
US8318803B2 (en) * 2003-10-31 2012-11-27 Tae-Yoon Kim EC SOD and use thereof
WO2005042583A1 (en) 2003-10-31 2005-05-12 Bio Clue & Solution Co., Ltd. Ec sod and cell transducing ec sod and use thereof
US7332159B2 (en) 2004-09-30 2008-02-19 Board Of Regents Of The University Of Nebraska Method and composition for inhibiting reperfusion injury in the brain
US11382895B2 (en) 2008-05-23 2022-07-12 National Jewish Health Methods for treating injury associated with exposure to an alkylating species
US8465413B2 (en) 2010-11-25 2013-06-18 Coloplast A/S Method of treating Peyronie's disease
EP3775177A1 (de) * 2018-04-03 2021-02-17 Cornell University Gentherapie für oxidativen stress

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK145950C (da) * 1979-05-17 1983-09-26 Forenede Bryggerier As Fremgangsmaade til isolering af cu,zn-superoxid-dismutase fra vandige oploesninger indeholdende dette enzym sammen med ledsagende proteiner
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
JPS5729285A (en) * 1980-07-30 1982-02-17 Takeda Chem Ind Ltd Superoxide dismutase and its preparation
EP0091539B2 (de) * 1982-03-31 1996-11-27 Ajinomoto Co., Inc. Das Polypeptid Interleukin-2 kodierendes Gen, rekombinante, dieses Gen enthaltende DNA, diese rekombinante DNA aufweisende Zelllinien und Verfahren zur Herstellung von Interleukin-2 unter Verwendung der genannten Zellen
IT1150598B (it) * 1982-12-14 1986-12-17 Ines Bianchi Procedimento per la purificazione della superossidodismutasi mediante cromatografia di affinita'
DE3486452T2 (de) * 1983-10-03 1997-11-06 Chiron Corp., Emeryville, Calif. Superoxiddismutase und deren Expression in Mikroorganismen
US4742004A (en) * 1984-08-27 1988-05-03 Bio-Technology General Corp. Method for producing enzymatically active eucaryotic sod in bacteria
JPS61111690A (ja) * 1984-11-06 1986-05-29 Ube Ind Ltd 組換えｄｎａおよびその用途
DK402785D0 (da) * 1985-09-03 1985-09-03 Syn Tek Ab Fremgangsmaade til fremstilling af et enzym
EP0213628A3 (de) * 1985-09-03 1988-09-21 Yeda Research And Development Company, Ltd. Expression von Superoxiddismutase in eukaryotischen Zellen
CA1289092C (en) * 1987-01-15 1991-09-17 Novartis Vaccines And Diagnostics, Inc. Thermostable human cu/zn superoxide dismutase muteins
EP0414915B1 (de) * 1989-03-06 1996-06-12 Suntory Limited Neue superoxyd-dismutase

Also Published As

Publication number Publication date
EP0593435A1 (de) 1994-04-27
DE69029406D1 (en) 1997-01-23
AU6444190A (en) 1991-04-18
US5366729A (en) 1994-11-22
DK455789D0 (da) 1989-09-15
EP0593435B1 (de) 1996-12-11
WO1991004315A1 (en) 1991-04-04

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