ATE148120T1 - (1,2,4-triazolo(4,3-a>chinoxalinverbindungen deren herstellung und verwendung - Google Patents

(1,2,4-triazolo(4,3-a>chinoxalinverbindungen deren herstellung und verwendung

Info

Publication number
ATE148120T1
ATE148120T1 AT94915514T AT94915514T ATE148120T1 AT E148120 T1 ATE148120 T1 AT E148120T1 AT 94915514 T AT94915514 T AT 94915514T AT 94915514 T AT94915514 T AT 94915514T AT E148120 T1 ATE148120 T1 AT E148120T1
Authority
AT
Austria
Prior art keywords
alkyl
triazolo
optionally substituted
treatment
containing heterocyclic
Prior art date
Application number
AT94915514T
Other languages
English (en)
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Lone Jeppesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK53593A external-priority patent/DK53593D0/da
Priority claimed from DK128793A external-priority patent/DK128793D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE148120T1 publication Critical patent/ATE148120T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT94915514T 1993-05-06 1994-04-28 (1,2,4-triazolo(4,3-a>chinoxalinverbindungen deren herstellung und verwendung ATE148120T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK53593A DK53593D0 (da) 1993-05-06 1993-05-06 Oe1,2,4aatriazolooe4,3-aaaquinoxalinonforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse
DK128793A DK128793D0 (de) 1993-11-12 1993-11-12

Publications (1)

Publication Number Publication Date
ATE148120T1 true ATE148120T1 (de) 1997-02-15

Family

ID=26064177

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94915514T ATE148120T1 (de) 1993-05-06 1994-04-28 (1,2,4-triazolo(4,3-a>chinoxalinverbindungen deren herstellung und verwendung

Country Status (19)

Country Link
US (1) US5532236A (de)
EP (1) EP0698024B1 (de)
JP (1) JPH08509747A (de)
KR (1) KR100304177B1 (de)
CN (1) CN1041931C (de)
AT (1) ATE148120T1 (de)
AU (1) AU683062B2 (de)
CA (1) CA2162023A1 (de)
DE (1) DE69401583T2 (de)
DK (1) DK0698024T3 (de)
ES (1) ES2097652T3 (de)
FI (1) FI955304A7 (de)
GR (1) GR3023001T3 (de)
HU (1) HUT73983A (de)
IL (1) IL109530A (de)
NO (1) NO305516B1 (de)
NZ (1) NZ266127A (de)
TW (1) TW377354B (de)
WO (1) WO1994026746A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU694554B2 (en) * 1994-09-16 1998-07-23 Novo Nordisk A/S {1,2,4}triazolo{4,3-a}quinoxalinone derivatives, their preparation and use
DK0783504T3 (da) * 1994-09-16 2000-08-14 Novo Nordisk As (1,2,4)triazolo (4,3-a)guinoxalinon-derivater, deres fremstilling og anvendelse som antagonister af ampa-receptorer
DE19510965A1 (de) * 1995-03-24 1996-09-26 Asta Medica Ag Neue Pyrido/3,2-e/pyrazinone mit antiasthmatischer Wirksamkeit und Verfahren zu deren Herstellung
CN1103772C (zh) 1996-05-15 2003-03-26 辉瑞大药厂 新的2,3－二取代－4(3h)－喹唑啉酮类化合物
ZA9711274B (en) * 1996-12-16 1998-06-23 Warner Lambert Co Tricyclic quinoxaline derivatives as neuroprotective agents.
US6015800A (en) * 1997-09-03 2000-01-18 Warner-Lambert Company Substituted quinoxaline-2-ones as glutamate receptor antagonists
US6323208B1 (en) 1997-09-05 2001-11-27 Pfizer Inc Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
CN1285834A (zh) 1997-11-11 2001-02-28 小野药品工业株式会社 稠合吡嗪化合物
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
EP2338492A1 (de) 2009-12-24 2011-06-29 Universidad del Pais Vasco Verfahren und Zusammensetzung zur Behandlung von Alzheimer
WO2016199943A1 (en) * 2015-06-11 2016-12-15 Takeda Pharmaceutical Company Limited Heterocyclic compounds
DK3823971T3 (da) * 2018-07-20 2022-09-05 Gruenenthal Gmbh Substituerede triazol-quinoxalin-derivater

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400382A (en) * 1980-05-09 1983-08-23 Usv Pharmaceutical Corporation Thiazoloquinoxalin-1,4-diones for treating allergy
DK162491D0 (da) * 1991-09-20 1991-09-20 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne

Also Published As

Publication number Publication date
DE69401583D1 (de) 1997-03-06
DE69401583T2 (de) 1997-06-12
NO954402L (no) 1996-01-05
FI955304L (fi) 1995-11-06
US5532236A (en) 1996-07-02
FI955304A0 (fi) 1995-11-06
GR3023001T3 (en) 1997-07-30
AU6720094A (en) 1994-12-12
ES2097652T3 (es) 1997-04-01
DK0698024T3 (da) 1997-07-28
IL109530A (en) 1997-01-10
CA2162023A1 (en) 1994-11-24
HUT73983A (en) 1996-10-28
IL109530A0 (en) 1994-08-26
CN1125446A (zh) 1996-06-26
FI955304A7 (fi) 1995-11-06
EP0698024A1 (de) 1996-02-28
NO305516B1 (no) 1999-06-14
CN1041931C (zh) 1999-02-03
KR100304177B1 (ko) 2001-11-22
TW377354B (en) 1999-12-21
EP0698024B1 (de) 1997-01-22
JPH08509747A (ja) 1996-10-15
WO1994026746A1 (en) 1994-11-24
HU9503157D0 (en) 1996-01-29
AU683062B2 (en) 1997-10-30
KR960701877A (ko) 1996-03-28
NZ266127A (en) 1997-11-24
NO954402D0 (no) 1995-11-03

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee