ATE152171T1 - Lymphozyten-assoziiertes zelloberflächenprotein - Google Patents

Lymphozyten-assoziiertes zelloberflächenprotein

Info

Publication number
ATE152171T1
ATE152171T1 AT90301884T AT90301884T ATE152171T1 AT E152171 T1 ATE152171 T1 AT E152171T1 AT 90301884 T AT90301884 T AT 90301884T AT 90301884 T AT90301884 T AT 90301884T AT E152171 T1 ATE152171 T1 AT E152171T1
Authority
AT
Austria
Prior art keywords
lymphocyte
lam
cell surface
associated cell
surface protein
Prior art date
Application number
AT90301884T
Other languages
English (en)
Inventor
Thomas F Tedder
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Application granted granted Critical
Publication of ATE152171T1 publication Critical patent/ATE152171T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564—Selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT90301884T 1989-02-21 1990-02-21 Lymphozyten-assoziiertes zelloberflächenprotein ATE152171T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31310989A 1989-02-21 1989-02-21

Publications (1)

Publication Number Publication Date
ATE152171T1 true ATE152171T1 (de) 1997-05-15

Family

ID=23214421

Family Applications (2)

Application Number Title Priority Date Filing Date
AT90301884T ATE152171T1 (de) 1989-02-21 1990-02-21 Lymphozyten-assoziiertes zelloberflächenprotein
AT96112230T ATE252637T1 (de) 1989-02-21 1990-02-21 Antikörper gegen lymphozyten-assoziiertes zelloberflächenprotein

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT96112230T ATE252637T1 (de) 1989-02-21 1990-02-21 Antikörper gegen lymphozyten-assoziiertes zelloberflächenprotein

Country Status (11)

Country Link
US (3) US6020152A (de)
EP (2) EP0770680B1 (de)
JP (3) JP3367661B2 (de)
AT (2) ATE152171T1 (de)
CA (1) CA2010321C (de)
DE (2) DE69034112T2 (de)
DK (2) DK0386906T3 (de)
ES (2) ES2208711T3 (de)
GR (1) GR3024204T3 (de)
HK (1) HK1007331A1 (de)
SG (1) SG43062A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776775A (en) * 1989-02-21 1998-07-07 Dana-Farber Cancer Institute Anti-LAM 1-3 antibody and hybridoma
US5116964A (en) * 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
US6406697B1 (en) 1989-02-23 2002-06-18 Genentech, Inc. Hybrid immunoglobulins
US5225538A (en) * 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5891841A (en) * 1991-06-11 1999-04-06 The Center For Blood Research, Inc. Methods of using intercellular adhesion molecule-3 (ICAM-3), antibodies thereto, and soluble fragments thereof
AU2305192A (en) * 1991-06-25 1993-01-25 Dana-Farber Cancer Institute Monoclonal antibody to lymphocyte-associated cell surface protein
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US5773218A (en) * 1992-01-27 1998-06-30 Icos Corporation Method to identify compounds which modulate ICAM-related protein interactions
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
EP0578819A4 (de) * 1992-01-27 1994-10-12 Icos Corp Icam ähnliche proteine.
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US5316920A (en) * 1992-04-17 1994-05-31 Dana-Faber Cancer Institute, Inc. Lymphocyte activation antigen HB15, a member of the immunoglobulin superfamily
US5723125A (en) * 1995-12-28 1998-03-03 Tanox Biosystems, Inc. Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
AU2183300A (en) * 1998-12-18 2000-07-12 Incyte Pharmaceuticals, Inc. Lymphocytic membrane proteins
RU2179858C1 (ru) * 2001-02-28 2002-02-27 Цыпин Анатолий Борисович Эндоскопическая спленотерапия гастродуоденальных язв
JP2007531738A (ja) * 2004-04-02 2007-11-08 アムジエン・インコーポレーテツド ＩＬ−１ｒａの凝集を低下させる方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783330A (en) * 1984-11-15 1988-11-08 New England Medical Center Hospitals, Inc. Monoclonal antibodies to activated platelets
US4835255A (en) * 1987-03-26 1989-05-30 Yale University T-cell membrane protein
US5389520A (en) * 1989-02-21 1995-02-14 Dana-Farber Cancer Institute, Inc. Specific detection of cell surface receptor leukocyte adhesion molecule-1
US5098833A (en) * 1989-02-23 1992-03-24 Genentech, Inc. DNA sequence encoding a functional domain of a lymphocyte homing receptor
US5216131A (en) * 1989-02-23 1993-06-01 Genentech, Inc. Lymphocyte homing receptors
US5026537A (en) * 1989-04-06 1991-06-25 Centocor, Inc. Methods for imaging atherosclerotic plaque
US5227369A (en) * 1991-07-11 1993-07-13 The Regents Of The University Of California Compositions and methods for inhibiting leukocyte adhesion to cns myelin
WO1993002698A1 (en) * 1991-07-29 1993-02-18 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies to leukocyte adhesion molecule-1

Also Published As

Publication number Publication date
US5830471A (en) 1998-11-03
DE69030522T2 (de) 1997-12-04
DK0386906T3 (da) 1997-10-13
US6451981B1 (en) 2002-09-17
ATE252637T1 (de) 2003-11-15
ES2102360T3 (es) 1997-08-01
DK0770680T3 (da) 2004-02-23
JPH0322982A (ja) 1991-01-31
EP0770680A2 (de) 1997-05-02
EP0770680B1 (de) 2003-10-22
SG43062A1 (en) 1997-10-17
EP0386906B1 (de) 1997-04-23
EP0386906A1 (de) 1990-09-12
CA2010321A1 (en) 1990-08-21
DE69034112D1 (de) 2003-11-27
EP0770680A3 (de) 1997-05-07
HK1011050A1 (en) 1999-07-02
GR3024204T3 (en) 1997-10-31
US6020152A (en) 2000-02-01
ES2208711T3 (es) 2004-06-16
JP2001017189A (ja) 2001-01-23
DE69034112T2 (de) 2004-07-29
JP2005230016A (ja) 2005-09-02
CA2010321C (en) 2004-04-06
DE69030522D1 (de) 1997-05-28
HK1007331A1 (en) 1999-04-09
JP3367661B2 (ja) 2003-01-14

Similar Documents

Publication Publication Date Title
DE69030522D1 (de) Lymphozyten-assoziiertes Zelloberflächenprotein
DE69027121T2 (de) Bindeligande für tumornekrosisfaktor
SHISHIBA et al. Direct evidence for human thyroidal stimulation by LATS-protector
DE3650499T2 (de) Verwendung von "Cartilage-inducing Factor" (CIF) zur Behandlung von hemato- oder lymphopoietischen Krankheiten
FI971406A0 (fi) TIE-2-ligandeja ja menetelmiä niiden valmistamiseksi ja käyttämiseksi
ATE214943T1 (de) Therapeutische zusammensetzungen die monoklonale antikörper enthalten gegen den menschlichen rezeptor für epidermalen wachstumsfaktor
DE69434538D1 (de) Vaskularer endothelialer wachstumsfaktor 2
DE69230112D1 (de) Fortschrittliches arzneistoffabgabesystem und verfahren zur behandlung von psychiatrischen, neurologischen und anderen erkrankungen mit carbamazepin
NO951609D0 (no) Antagonister for vaskulær endotelcellevekstfaktor
ATE132197T1 (de) Monoklonale antikörper
NO985904D0 (no) TIE-2-reseptorligander (TIE-ligand-3, TIE-ligand-4), samt anvendelse derav
RU94045984A (ru) Композиция, способ обработки неопластической клетки, способ уничтожения опухолевых клеток
ATE93730T1 (de) Methode zur erhoehung des wachstums des brustzellgewebes.
ATE306278T1 (de) Behandlung von knochenleiden mit adrenomedullin
FI885797A7 (fi) Peptidejä, menetelmä niiden valmistamiseksi, niiden käyttö vasta-aineiden valmistamiseksi, sekä näiden käyttö ihmisen veren PAI-1-aktiivisuuden estämiseksi
ATE126437T1 (de) Verwendung von depogen zur behandlung von eingeschränktem blutkreislauf.
IT7849691A0 (it) Dell'organismo animale e trova il procedimento per la separazione dal suo impiego nelle neoplasie emati sangue di mammiferi di una frazione che peptidica che esalta i fattori umo rali e cellulari di difesa naturali

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time