ATE152171T1 - Lymphozyten-assoziiertes zelloberflächenprotein - Google Patents

Lymphozyten-assoziiertes zelloberflächenprotein

Info

Publication number
ATE152171T1
ATE152171T1 AT90301884T AT90301884T ATE152171T1 AT E152171 T1 ATE152171 T1 AT E152171T1 AT 90301884 T AT90301884 T AT 90301884T AT 90301884 T AT90301884 T AT 90301884T AT E152171 T1 ATE152171 T1 AT E152171T1
Authority
AT
Austria
Prior art keywords
lymphocyte
lam
cell surface
associated cell
surface protein
Prior art date
Application number
AT90301884T
Other languages
English (en)
Inventor
Thomas F Tedder
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Application granted granted Critical
Publication of ATE152171T1 publication Critical patent/ATE152171T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564Selectins, e.g. CD62
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT90301884T 1989-02-21 1990-02-21 Lymphozyten-assoziiertes zelloberflächenprotein ATE152171T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31310989A 1989-02-21 1989-02-21

Publications (1)

Publication Number Publication Date
ATE152171T1 true ATE152171T1 (de) 1997-05-15

Family

ID=23214421

Family Applications (2)

Application Number Title Priority Date Filing Date
AT90301884T ATE152171T1 (de) 1989-02-21 1990-02-21 Lymphozyten-assoziiertes zelloberflächenprotein
AT96112230T ATE252637T1 (de) 1989-02-21 1990-02-21 Antikörper gegen lymphozyten-assoziiertes zelloberflächenprotein

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT96112230T ATE252637T1 (de) 1989-02-21 1990-02-21 Antikörper gegen lymphozyten-assoziiertes zelloberflächenprotein

Country Status (11)

Country Link
US (3) US6020152A (de)
EP (2) EP0386906B1 (de)
JP (3) JP3367661B2 (de)
AT (2) ATE152171T1 (de)
CA (1) CA2010321C (de)
DE (2) DE69034112T2 (de)
DK (2) DK0386906T3 (de)
ES (2) ES2102360T3 (de)
GR (1) GR3024204T3 (de)
HK (1) HK1007331A1 (de)
SG (1) SG43062A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776775A (en) * 1989-02-21 1998-07-07 Dana-Farber Cancer Institute Anti-LAM 1-3 antibody and hybridoma
US5225538A (en) * 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
US5116964A (en) * 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
US6406697B1 (en) 1989-02-23 2002-06-18 Genentech, Inc. Hybrid immunoglobulins
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5891841A (en) * 1991-06-11 1999-04-06 The Center For Blood Research, Inc. Methods of using intercellular adhesion molecule-3 (ICAM-3), antibodies thereto, and soluble fragments thereof
AU2305192A (en) * 1991-06-25 1993-01-25 Dana-Farber Cancer Institute Monoclonal antibody to lymphocyte-associated cell surface protein
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US5869262A (en) * 1992-01-27 1999-02-09 Icos Corporation Method for monitoring an inflammatory disease state by detecting circulating ICAM-R
EP0578819A4 (de) * 1992-01-27 1994-10-12 Icos Corp Icam ähnliche proteine.
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US5316920A (en) * 1992-04-17 1994-05-31 Dana-Faber Cancer Institute, Inc. Lymphocyte activation antigen HB15, a member of the immunoglobulin superfamily
US5723125A (en) * 1995-12-28 1998-03-03 Tanox Biosystems, Inc. Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
JP2002534961A (ja) * 1998-12-18 2002-10-22 インサイト・ファーマスーティカルズ・インコーポレイテッド リンパ球膜タンパク質
RU2179858C1 (ru) * 2001-02-28 2002-02-27 Цыпин Анатолий Борисович Эндоскопическая спленотерапия гастродуоденальных язв
PT1729810T (pt) * 2004-04-02 2018-11-22 Swedish Orphan Biovitrum Ab Publ Métodos de redução da agregação de il-ira

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783330A (en) * 1984-11-15 1988-11-08 New England Medical Center Hospitals, Inc. Monoclonal antibodies to activated platelets
US4835255A (en) * 1987-03-26 1989-05-30 Yale University T-cell membrane protein
US5389520A (en) * 1989-02-21 1995-02-14 Dana-Farber Cancer Institute, Inc. Specific detection of cell surface receptor leukocyte adhesion molecule-1
US5216131A (en) * 1989-02-23 1993-06-01 Genentech, Inc. Lymphocyte homing receptors
US5098833A (en) * 1989-02-23 1992-03-24 Genentech, Inc. DNA sequence encoding a functional domain of a lymphocyte homing receptor
US5026537A (en) * 1989-04-06 1991-06-25 Centocor, Inc. Methods for imaging atherosclerotic plaque
US5227369A (en) * 1991-07-11 1993-07-13 The Regents Of The University Of California Compositions and methods for inhibiting leukocyte adhesion to cns myelin
WO1993002698A1 (en) * 1991-07-29 1993-02-18 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies to leukocyte adhesion molecule-1

Also Published As

Publication number Publication date
EP0386906B1 (de) 1997-04-23
US6020152A (en) 2000-02-01
DK0770680T3 (da) 2004-02-23
EP0770680A2 (de) 1997-05-02
US6451981B1 (en) 2002-09-17
JP3367661B2 (ja) 2003-01-14
SG43062A1 (en) 1997-10-17
DE69030522T2 (de) 1997-12-04
GR3024204T3 (en) 1997-10-31
EP0770680A3 (de) 1997-05-07
DE69030522D1 (de) 1997-05-28
CA2010321C (en) 2004-04-06
CA2010321A1 (en) 1990-08-21
JP2001017189A (ja) 2001-01-23
EP0386906A1 (de) 1990-09-12
DK0386906T3 (da) 1997-10-13
ES2102360T3 (es) 1997-08-01
JPH0322982A (ja) 1991-01-31
HK1007331A1 (en) 1999-04-09
DE69034112D1 (de) 2003-11-27
HK1011050A1 (en) 1999-07-02
EP0770680B1 (de) 2003-10-22
US5830471A (en) 1998-11-03
ATE252637T1 (de) 2003-11-15
DE69034112T2 (de) 2004-07-29
JP2005230016A (ja) 2005-09-02
ES2208711T3 (es) 2004-06-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time