|
WO1990005183A1
(en)
*
|
1988-10-31 |
1990-05-17 |
Immunex Corporation |
Interleukin-4 receptors
|
|
WO1991003555A1
(en)
*
|
1989-09-07 |
1991-03-21 |
Schering Corporation |
Interleukin-4 receptors
|
|
DE59010908D1
(de)
|
1989-09-12 |
2000-08-10 |
Hoffmann La Roche |
TNF-bindende Proteine
|
|
EP0502080A4
(en)
*
|
1989-11-21 |
1993-02-10 |
The University Of Melbourne |
Anti-inflammatory compositions and methods
|
|
US20030064480A1
(en)
*
|
1990-06-28 |
2003-04-03 |
Leander Lauffer |
Fusion proteins with immunoglobulin portions, the preparation and use thereof
|
|
US7253264B1
(en)
|
1990-06-28 |
2007-08-07 |
Sanofi-Arentideutschland GmbH |
Immunoglobulin fusion proteins, their production and use
|
|
US5453491A
(en)
*
|
1990-09-11 |
1995-09-26 |
Kiyoshi Takatsu |
Murine interleukin-5 receptor
|
|
US5770197A
(en)
*
|
1991-06-27 |
1998-06-23 |
Bristol-Myers Squibb Company |
Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules
|
|
EP0611302B1
(de)
*
|
1991-10-15 |
2000-03-29 |
MULLARKEY, Michael F. |
Rezeptoren zur Behandlung von Entzündungen vom verzögerten Typ
|
|
CA2124338A1
(en)
*
|
1991-11-27 |
1993-06-10 |
Nobuyuki Harada |
Region of cytoplasmic domain of the human interleukin-4 receptor, as antagonists of il-4
|
|
DE4322330A1
(de)
*
|
1992-08-31 |
1994-03-03 |
Behringwerke Ag |
Verwendung des IL-4-Rezeptors zur Therapie, Prophylaxe und Diagnose von allergischen, viralen, parasitären und bakteriellen Erkrankungen sowie von Pilzinfektionen
|
|
US5714146A
(en)
*
|
1992-08-26 |
1998-02-03 |
Board Of Regents Of The University Of Washington |
IL-4 bone therapy
|
|
DE4228839A1
(de)
*
|
1992-08-29 |
1994-03-03 |
Behringwerke Ag |
Verfahren zum Nachweis und zur Bestimmung von Mediatoren
|
|
EP0604693A1
(de)
*
|
1992-12-29 |
1994-07-06 |
Schering-Plough |
Monoklonale Antikörper gegen den menschlichen Interleukin-4-Rezeptor und Hybridomen die diese produzieren
|
|
WO1994021282A1
(en)
*
|
1993-03-19 |
1994-09-29 |
Immunex Corporation |
Pharmaceutical compositions comprising a ligand complexed with a soluble receptor
|
|
US5470952A
(en)
*
|
1993-10-20 |
1995-11-28 |
Regeneron Pharmaceuticals, Inc. |
CNTF and IL-6 antagonists
|
|
US5591825A
(en)
*
|
1994-07-05 |
1997-01-07 |
Tularik, Inc. |
Interleukin 4 signal transducers
|
|
US20020028798A1
(en)
*
|
1995-12-12 |
2002-03-07 |
Omeros Medical Systems |
Irrigation solution and method for inhibition of pain and inflammation
|
|
US7091181B2
(en)
|
1994-12-12 |
2006-08-15 |
Omeros Corporation |
Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors
|
|
US5795966A
(en)
|
1995-02-22 |
1998-08-18 |
Immunex Corp |
Antagonists of interleukin-15
|
|
KR100510234B1
(ko)
|
1995-06-29 |
2005-11-25 |
임뮤넥스 코포레이션 |
세포소멸을 유도하는 시토킨
|
|
US6541604B1
(en)
*
|
1996-01-08 |
2003-04-01 |
Genentech, Inc. |
Leptin receptor having a WSX motif
|
|
US7074397B1
(en)
|
1996-01-08 |
2006-07-11 |
Genentech, Inc. |
Method for enhancing proliferation or differentiation of a cell using ob protein
|
|
US20050019325A1
(en)
*
|
1996-01-08 |
2005-01-27 |
Carter Paul J. |
WSX receptor agonist antibodies
|
|
US7078494B1
(en)
*
|
1996-03-01 |
2006-07-18 |
Genetics Institute, Llc |
Antibodies to human IL-13bc and methods of their use in inhibiting IL-13 binding
|
|
US5710023A
(en)
*
|
1996-03-01 |
1998-01-20 |
Genetics Institute, Inc. |
IL-13 cytokine receptor chain
|
|
US20060205660A1
(en)
*
|
1996-06-20 |
2006-09-14 |
Sauvage Frederic D |
OB protein-immunoglobulin chimeras
|
|
US6586210B1
(en)
|
1996-08-23 |
2003-07-01 |
Human Genome Sciences, Inc. |
Polynucleotides encoding T1 receptor like ligand II
|
|
US6605271B2
(en)
*
|
1996-08-23 |
2003-08-12 |
Human Genome Sciences, Inc. |
T1 receptor-like ligand II and uses thereof
|
|
PT951551E
(pt)
|
1996-12-23 |
2008-10-28 |
Immunex Corp |
Ligando para receptor activador de nf-kb, ligando membro da superfamília de tnf
|
|
US6384203B1
(en)
|
1999-05-12 |
2002-05-07 |
Immunex Corporation |
Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
|
|
DE69840051D1
(de)
*
|
1997-10-29 |
2008-11-06 |
Genentech Inc |
Durch wnt-1 induzierbare gene
|
|
US6703488B1
(en)
*
|
1998-01-15 |
2004-03-09 |
Center For Molecular Medicine And Immunology |
Antibody/receptor targeting moiety for enhanced delivery of armed ligand
|
|
US6630140B1
(en)
*
|
1998-03-10 |
2003-10-07 |
The Children's Hospital Of Philadelphia |
Compositions and methods for treatment of asthma
|
|
DE69932247T2
(de)
|
1998-08-21 |
2007-05-31 |
Immunex Corp., Thousand Oaks |
Menschliches il-1 epsilon dna und polypeptide
|
|
EP1939297A1
(de)
|
1998-09-24 |
2008-07-02 |
Pharmacia & Upjohn Company LLC |
Alzheimerkrankheit-Sekretase
|
|
US6472179B2
(en)
|
1998-09-25 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Receptor based antagonists and methods of making and using
|
|
US7067144B2
(en)
*
|
1998-10-20 |
2006-06-27 |
Omeros Corporation |
Compositions and methods for systemic inhibition of cartilage degradation
|
|
US7553487B2
(en)
*
|
1998-12-14 |
2009-06-30 |
Genetics Institute, Llc |
Method and compositions for treating asthma
|
|
US7507706B1
(en)
|
1998-12-14 |
2009-03-24 |
Genetics Institute, Llc |
Cytokine receptor chain
|
|
US20040220103A1
(en)
*
|
1999-04-19 |
2004-11-04 |
Immunex Corporation |
Soluble tumor necrosis factor receptor treatment of medical disorders
|
|
US20010021380A1
(en)
*
|
1999-04-19 |
2001-09-13 |
Pluenneke John D. |
Soluble tumor necrosis factor receptor treatment of medical disorders
|
|
GB9912350D0
(en)
*
|
1999-05-26 |
1999-07-28 |
European Molecular Biology Lab Embl |
Modified cytokine
|
|
US6693172B1
(en)
|
1999-05-27 |
2004-02-17 |
Pharmacia And Upjohn Company |
Double mutant alpha-7 nicotinic acetylcholine receptor
|
|
US6455290B1
(en)
|
1999-07-09 |
2002-09-24 |
Pharmacia Italia S.P.A. |
Tankyrase homolog protein (THP), nucleic acids, and methods related to the same
|
|
AU2000263446A1
(en)
*
|
1999-07-13 |
2001-01-30 |
Genaissance Pharmaceuticals, Inc. |
Drug target isogenes: polymorphisms in the interleukin 4 receptor alpha gene
|
|
WO2001031005A2
(en)
|
1999-10-22 |
2001-05-03 |
Pharmacia & Upjohn Company |
Drosophila g protein coupled receptors, nucleic acids, and methods related to the same
|
|
AU2077801A
(en)
*
|
1999-12-10 |
2001-06-18 |
Human Genome Sciences, Inc. |
T1 receptor-like ligand ii and uses thereof
|
|
EP1239869B1
(de)
|
1999-12-20 |
2013-08-28 |
Immunex Corporation |
Tweak rezeptor
|
|
US6846486B1
(en)
|
2000-02-24 |
2005-01-25 |
Advanced Biotherapy Concepts, Inc. |
Method of treating allergy by administering an anti-histamine antibody
|
|
US6498026B2
(en)
|
2000-02-25 |
2002-12-24 |
Hercules Incorporated |
Variant galactose oxidase, nucleic acid encoding same, and methods of using same
|
|
EP2241328A1
(de)
*
|
2000-05-12 |
2010-10-20 |
Immunex Corporation |
Interleukin-1 Inhibitoren zur Behandlung von Erkrankungen
|
|
EP1158058A1
(de)
*
|
2000-05-19 |
2001-11-28 |
Centre National De La Recherche Scientifique |
Zusammensetzungen und Verfahren geeignet für Nukleinsäureanalyse
|
|
EP1297112A2
(de)
|
2000-05-22 |
2003-04-02 |
PHARMACIA & UPJOHN COMPANY |
Neue matrix-metalloproteasen
|
|
WO2001092340A2
(en)
|
2000-05-26 |
2001-12-06 |
Immunex Corporation |
Use of interleukin-4 antagonists and compositions thereof
|
|
US7259244B2
(en)
|
2000-06-16 |
2007-08-21 |
Nerviano Medical Sciences S.R.L. |
Human homologue of the DBF4/ASK1 protein, nucleic acids, and methods related to the same
|
|
US6686449B2
(en)
|
2000-06-30 |
2004-02-03 |
Pharmacia & Upjohn Company |
Mutant presenilin 1 polypeptides
|
|
WO2002002639A2
(en)
|
2000-07-05 |
2002-01-10 |
Pharmacia & Upjohn Company |
Human ion channels
|
|
US20020076409A1
(en)
*
|
2000-07-12 |
2002-06-20 |
March Carl J. |
Method for treating cancer
|
|
US6652854B2
(en)
*
|
2000-08-08 |
2003-11-25 |
Immunex Corporation |
Methods for treating autoimmune and chronic inflammatory conditions using antagonists of CD30 or CD30L
|
|
EP1351704B1
(de)
*
|
2000-12-21 |
2007-03-07 |
Nektar Therapeutics |
Lagerstabile pulverzusammensetzungen mit interleukin-4 rezeptor
|
|
WO2003035887A1
(en)
*
|
2001-09-20 |
2003-05-01 |
Immunex Corporation |
Selection of cells expressing heteromeric polypeptides
|
|
ATE434624T1
(de)
|
2001-10-04 |
2009-07-15 |
Immunex Corp |
Ul16-bindungsprotein 4
|
|
US20050112616A1
(en)
*
|
2001-12-10 |
2005-05-26 |
William Lee |
Functionalized materials and libraries thereof
|
|
WO2003083066A2
(en)
|
2002-03-27 |
2003-10-09 |
Immunex Corporation |
Methods for increasing polypeptide production
|
|
DK1408106T3
(da)
*
|
2002-10-11 |
2007-06-11 |
Sentoclone Ab |
Cancer immunterapi
|
|
WO2004034988A2
(en)
|
2002-10-16 |
2004-04-29 |
Amgen Inc. |
Human anti-ifn-ϝ neutralizing antibodies as selective ifn-ϝ pathway inhibitors
|
|
EP1572984B8
(de)
|
2002-12-16 |
2016-06-01 |
Technion Research & Development Foundation Ltd. |
Feederzellfrei, xenofrei kultursystem für menschlicher embryonaler stammzellen
|
|
BRPI0406776A
(pt)
*
|
2003-01-18 |
2005-12-27 |
Childrens Hosp Medical Center |
Composição farmacêutica, método de avaliação fisiológica e uso de pelo menos um dentre um inibidor de uma molécula semelhante a resistina (alfa) (relm(alfa)), uma molécula semelhante a resistina ß (relmß), um regulador de expressão de relm(alfa) ou um regulador de expressão de relmß
|
|
EP1444989A1
(de)
*
|
2003-02-07 |
2004-08-11 |
Giorgio Dr. Stassi |
Sensibilisierung von Zellen für die Apoptose durch selektive Blockade von Zytokinen
|
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
ATE554108T1
(de)
|
2003-07-25 |
2012-05-15 |
Amgen Inc |
Verfahren bezüglich ldcam und crtam
|
|
NZ547588A
(en)
*
|
2003-11-07 |
2009-05-31 |
Immunex Corp |
Antibodies that bind interleukin-4 receptor
|
|
EP2385069A3
(de)
|
2003-11-12 |
2012-05-30 |
Biogen Idec MA Inc. |
Neonataler Fc-Rezeptor (FcRn)-bindende Polypeptidvarianten, dimere Fc-Bindungsproteine und damit in Zusammenhang stehende Verfahren
|
|
JP4943161B2
(ja)
*
|
2003-12-23 |
2012-05-30 |
ジェネンテック, インコーポレイテッド |
新規抗il13モノクローナル抗体での癌の処置
|
|
EP1723173B1
(de)
|
2004-02-27 |
2008-05-14 |
Regeneron Pharmaceuticals, Inc. |
Il-4/il-13-spezifische polypetide und deren therapeutische verwendung
|
|
DE602005020755D1
(de)
|
2004-03-05 |
2010-06-02 |
Univ Illinois |
Peptidträger für die verabreichung von arzneimitteln
|
|
US7319015B2
(en)
|
2004-03-16 |
2008-01-15 |
The Regents Of The University Of Michigan |
Methods and compositions for using alveolar macrophage phospholipase A2
|
|
US7582442B2
(en)
|
2004-03-16 |
2009-09-01 |
The Regents Of The University Of Michigan |
Methods and compositions for using aleveolar macrophage phospholipase A2
|
|
AU2005229009A1
(en)
*
|
2004-03-23 |
2005-10-13 |
Amgen, Inc. |
Monoclonal antibodies specific for human OX40L (CD 134L)
|
|
US7541158B2
(en)
|
2004-04-14 |
2009-06-02 |
Monell Chemical Senses Center |
Taste receptors of the T1R family from domestic dog
|
|
EA013071B1
(ru)
|
2004-04-23 |
2010-02-26 |
ФАРМАЦИЯ ЭНД АПДЖОН КОМПАНИ ЭлЭлСи |
Способ получения вируса репродуктивно-респираторного синдрома свиней (pprsv) и способ получения pprsv вакцины
|
|
AR049390A1
(es)
*
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
Anticuerpos contra la interleuquina-13 humana y usos de los mismos
|
|
US20090098142A1
(en)
*
|
2004-06-09 |
2009-04-16 |
Kasaian Marion T |
Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
|
|
US7501121B2
(en)
*
|
2004-06-17 |
2009-03-10 |
Wyeth |
IL-13 binding agents
|
|
AU2006203889A1
(en)
|
2005-01-05 |
2006-07-13 |
Biogen Idec Ma Inc. |
CRIPTO binding molecules
|
|
WO2006138181A2
(en)
*
|
2005-06-14 |
2006-12-28 |
Amgen Inc. |
Self-buffering protein formulations
|
|
US20070009479A1
(en)
*
|
2005-06-17 |
2007-01-11 |
Aerovance, Inc. |
Methods for treating dermatitis using mutant human IL-4 compositions
|
|
KR20070009269A
(ko)
|
2005-07-15 |
2007-01-18 |
한국생명공학연구원 |
재조합단백질 생산용 단백질융합인자 라이브러리 및이로부터 획득된 단백질융합인자
|
|
CA2627446A1
(en)
*
|
2005-11-21 |
2007-05-31 |
Laboratoires Serono S.A. |
Compositions and methods of producing hybrid antigen binding molecules and uses thereof
|
|
AU2006328943B2
(en)
*
|
2005-12-21 |
2011-07-21 |
Sentoclone International Ab |
Improved method for expansion of tumour-reactive T-lymphocytes for immunotherapy of patients with cancer
|
|
US8101173B2
(en)
*
|
2005-12-21 |
2012-01-24 |
Sentoclone International Ab |
Method for treating urinary bladder cancer
|
|
US8211425B2
(en)
*
|
2005-12-21 |
2012-07-03 |
Sentoclone International Ab |
Method for treating disseminated cancer
|
|
AU2006328945B2
(en)
*
|
2005-12-21 |
2011-06-30 |
Sentoclone International Ab |
Method for treating malignant melanoma
|
|
US8129334B2
(en)
|
2006-03-31 |
2012-03-06 |
The Regents Of The University Of California |
Methods and compositions for treating neurodegenerative disorders and Alzheimer'S disease and improving normal memory
|
|
EP2041576B1
(de)
|
2006-06-21 |
2011-08-10 |
Apogenix GmbH |
Differentielle cytokinexpression bei einer menschlichen krebserkrankung
|
|
AU2007271349A1
(en)
*
|
2006-07-06 |
2008-01-10 |
Apogenix Gmbh |
Human IL-4 muteins in combination with chemotherapeutics or pro-apoptotic agents in cancer therapy
|
|
CA2662549C
(en)
|
2006-09-08 |
2014-10-28 |
Amgen Inc. |
Il-1 family variants
|
|
MX353340B
(es)
|
2006-09-13 |
2018-01-09 |
Abbvie Inc |
Mejoras de cultivos celulares.
|
|
EP2500414A1
(de)
|
2006-09-13 |
2012-09-19 |
Abbott Laboratories |
Verbesserungen an Zellkulturen
|
|
LT2769992T
(lt)
*
|
2006-10-02 |
2021-04-12 |
Regeneron Pharmaceuticals, Inc. |
Didelio afiniškumo žmogaus antikūnai, atpažįstantys žmogaus il-4 receptorių
|
|
US7608693B2
(en)
|
2006-10-02 |
2009-10-27 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human IL-4 receptor
|
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
|
US20080260820A1
(en)
*
|
2007-04-19 |
2008-10-23 |
Gilles Borrelly |
Oral dosage formulations of protease-resistant polypeptides
|
|
RU2009140134A
(ru)
*
|
2007-04-23 |
2011-05-27 |
Вайет (Us) |
Способы и композиции для лечения и мониторинга лечения связанных с ил-13 нарушений
|
|
RS56743B1
(sr)
|
2007-08-21 |
2018-03-30 |
Amgen Inc |
Humani c-fms antigen vezujući proteini
|
|
TW200918553A
(en)
|
2007-09-18 |
2009-05-01 |
Amgen Inc |
Human GM-CSF antigen binding proteins
|
|
DK2245064T3
(da)
*
|
2007-12-21 |
2014-10-27 |
Medimmune Ltd |
BINDINGSELEMENTER TIL INTERLEUKIN-4-RECEPTOR-ALFA (IL-4Ralfa)
|
|
US8092804B2
(en)
|
2007-12-21 |
2012-01-10 |
Medimmune Limited |
Binding members for interleukin-4 receptor alpha (IL-4Rα)-173
|
|
GB0803076D0
(en)
|
2008-02-20 |
2008-03-26 |
Univ Ghent |
Mucosal Membrane Receptor and uses thereof
|
|
JP5646457B2
(ja)
|
2008-04-29 |
2014-12-24 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリン及びその使用
|
|
EP2113262B1
(de)
*
|
2008-04-29 |
2013-11-06 |
Proxy Biomedical Limited |
Gewebereparaturimplantat
|
|
EP3002299A1
(de)
|
2008-06-03 |
2016-04-06 |
AbbVie Inc. |
Dual-variable- domain-immunglobuline und ihre verwendungen
|
|
PE20100054A1
(es)
|
2008-06-03 |
2010-03-03 |
Abbott Lab |
Inmunoglobulina con dominio variable dual
|
|
EP2318036B1
(de)
|
2008-06-30 |
2015-06-03 |
The Regents of the University of Michigan |
Aktivität von lysosomaler phospholipase a2 (lpla2) als diagnostisches und therapeutisches target zur identifizierung und behandlung von systemischem lupus erythematodes
|
|
MX2010014574A
(es)
|
2008-07-08 |
2011-04-27 |
Abbott Lab |
Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas.
|
|
WO2010006808A1
(en)
*
|
2008-07-18 |
2010-01-21 |
Sentoclone Ab |
Composition comprising in vitro expanded t-lymphocytes and vessel formation inhibitors suitable in the treatment of cancer
|
|
US8815794B2
(en)
|
2008-08-28 |
2014-08-26 |
The Research Foundation For The State University Of New York |
Treatment of amyloidoses using myelin basic protein and fragments thereof
|
|
KR101498668B1
(ko)
|
2008-12-04 |
2015-03-06 |
한국생명공학연구원 |
고분비성 단백질의 스크리닝 및 재조합 단백질의 생산을 위한 융합 파트너로서 그의 용도
|
|
JO3382B1
(ar)
|
2008-12-23 |
2019-03-13 |
Amgen Inc |
أجسام مضادة ترتبط مع مستقبل cgrp بشري
|
|
US20120076754A1
(en)
|
2009-05-20 |
2012-03-29 |
Ziad Mallat |
Use of IL-17 Polypeptides for Use in the Prevention or Treatment of Atherosclerosis
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
JO3244B1
(ar)
|
2009-10-26 |
2018-03-08 |
Amgen Inc |
بروتينات ربط مستضادات il – 23 البشرية
|
|
EP2501398A1
(de)
|
2009-11-06 |
2012-09-26 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Verfahren und pharmazeutische zusammensetzungen zur behandlung von atherosklerose
|
|
KR101808751B1
(ko)
|
2009-11-13 |
2017-12-13 |
그리폴스 테라퓨틱스 인코포레이티드 |
폰 빌레브란트 인자(vWF)-함유 제제, 및 그와 관련된 방법, 키트 및 용도
|
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
|
US20130023473A1
(en)
|
2010-01-20 |
2013-01-24 |
Stephane Germain |
Methods and pharmaceutical composition for the preservation of vascular endothelial cell barrier integrity
|
|
AU2011237365B2
(en)
|
2010-04-09 |
2015-01-29 |
Amgen Inc. |
BTNL9 proteins, nucleic acids, and antibodies and uses thereof
|
|
JP2013523184A
(ja)
|
2010-04-15 |
2013-06-17 |
アムジエン・インコーポレーテツド |
ヒトFGF受容体およびβ−KLOTHO結合性タンパク質
|
|
HRP20191305T1
(hr)
|
2010-07-09 |
2019-10-18 |
Bioverativ Therapeutics Inc. |
Preradive jednolančane molekule i polipeptidi izrađeni koristeći iste
|
|
US8735546B2
(en)
|
2010-08-03 |
2014-05-27 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
EP2601287B1
(de)
|
2010-08-05 |
2015-01-07 |
Amgen Inc. |
Dipeptide zur erhöhung des ertrags und der lebensfähigkeit von zellkulturen
|
|
PH12013500337A1
(en)
|
2010-08-26 |
2017-08-23 |
Abbvie Inc |
Dual variable domain immunoglobulins and uses thereof
|
|
US20130195863A1
(en)
|
2010-09-28 |
2013-08-01 |
Philippe Clezardin |
Methods and Pharmaceutical Compositions for the Treatment of Bone Density Related Diseases
|
|
WO2012117336A2
(en)
|
2011-02-28 |
2012-09-07 |
Istituto Di Ricovero E Cura A Carattere Scientifico Materno-Infantile Burlo Garofolo - Ospedale Di Alta Specializzazione E Di Rilievo Nazionale Per La Salute Della Donna E Del Bambino |
Apoptosis-inducing molecules and uses therefor
|
|
MX348071B
(es)
|
2011-03-16 |
2017-05-26 |
Amgen Inc |
Variantes de fc.
|
|
WO2012145682A1
(en)
|
2011-04-21 |
2012-10-26 |
Amgen Inc. |
A method for culturing mammalian cells to improve recombinant protein production
|
|
EP2707018B1
(de)
|
2011-05-10 |
2015-11-04 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
Verfahren und pharmazeutische zusammensetzungen zur behandlung von autoimmunerkrankungen
|
|
US9574002B2
(en)
|
2011-06-06 |
2017-02-21 |
Amgen Inc. |
Human antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor
|
|
EP2535714A1
(de)
*
|
2011-06-16 |
2012-12-19 |
Istituto Nazionale Di Genetica Molecolare-INGM |
Biomarker für Autoimmun-Lebererkrankungen und Verwendungen davon
|
|
KR101662412B1
(ko)
|
2011-07-01 |
2016-10-04 |
암젠 인크 |
포유동물 세포 배양
|
|
WO2013009971A1
(en)
|
2011-07-12 |
2013-01-17 |
E. I. Du Pont De Nemours And Company |
Detection and screening method and materials useful in performance thereof
|
|
US9738707B2
(en)
|
2011-07-15 |
2017-08-22 |
Biogen Ma Inc. |
Heterodimeric Fc regions, binding molecules comprising same, and methods relating thereto
|
|
US20140234330A1
(en)
|
2011-07-22 |
2014-08-21 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
|
KR20140058669A
(ko)
|
2011-09-02 |
2014-05-14 |
암젠 인크 |
의약품 및 의약품의 광 노출을 분석하는 방법
|
|
ES2806146T3
(es)
|
2011-09-22 |
2021-02-16 |
Amgen Inc |
Proteínas de unión al antígeno CD27L
|
|
WO2013050441A1
(en)
|
2011-10-05 |
2013-04-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for inhibiting or preventing platelet aggregation
|
|
EP2596802A1
(de)
|
2011-11-23 |
2013-05-29 |
PLS-Design GmbH |
Pharmazeutische Zusammensetzung zur Behandlung allergischer Reaktionen
|
|
WO2013079487A1
(en)
|
2011-11-28 |
2013-06-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Pharmaceutical composition for use in the treatment of dysfunction associated with aging
|
|
CA2858572C
(en)
|
2011-12-08 |
2023-01-17 |
Amgen Inc. |
Human lcat antigen binding proteins and their use in therapy
|
|
AR089231A1
(es)
|
2011-12-15 |
2014-08-06 |
Amgen Inc |
Metodo de floculacion
|
|
US9120870B2
(en)
|
2011-12-30 |
2015-09-01 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-13 and IL-17
|
|
HUE039033T2
(hu)
|
2012-01-10 |
2018-12-28 |
Biogen Ma Inc |
Terápiás molekulák transzportjának fokozása a vér-agy gáton keresztül
|
|
DK3431492T3
(da)
|
2012-04-27 |
2021-03-08 |
Amgen Inc |
Humane cd30-ligandantigen-bindende proteiner
|
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
|
WO2013182650A1
(en)
|
2012-06-06 |
2013-12-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method and pharmaceutical composition for use in the treatment of cancer
|
|
EP2674168A1
(de)
|
2012-06-14 |
2013-12-18 |
PLS-Design GmbH |
Modulation von Effektor-T-Zell-Antworten durch lokale Depletion des Komplement-Faktors C3
|
|
AU2013292510A1
(en)
|
2012-07-19 |
2015-02-05 |
Amgen Inc. |
Human BTNL3 proteins, nucleic acids, and antibodies and uses thereof
|
|
IL312711A
(en)
|
2012-08-21 |
2024-07-01 |
Regeneron Pharma |
Methods for the treatment or prevention of asthma through the administration of an antagonist to 4R-IL
|
|
KR102576903B1
(ko)
|
2012-09-07 |
2023-09-13 |
리제너론 파아마슈티컬스, 인크. |
Il-4r 길항제 투여로 아토피성 피부염을 치료하는 방법
|
|
US9309318B2
(en)
|
2012-10-17 |
2016-04-12 |
Amgen, Inc. |
Compositions relating to anti-IL-21 receptor antibodies
|
|
AU2013337775B2
(en)
|
2012-11-01 |
2017-03-30 |
Abbvie Inc. |
Anti-VEGF/DLL4 dual variable domain immunoglobulins and uses thereof
|
|
UY35148A
(es)
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
|
JP6518192B2
(ja)
|
2012-12-07 |
2019-05-22 |
ノースカロライナ ステート ユニバーシティーNorth Carolina State University |
ベータ−ヘキソシルトランスフェラーゼ及びその使用
|
|
US20140199728A1
(en)
|
2013-01-14 |
2014-07-17 |
Amgen Inc. |
Methods of using cell-cycle inhibitors to modulate one or more properties of a cell culture
|
|
US10023608B1
(en)
|
2013-03-13 |
2018-07-17 |
Amgen Inc. |
Protein purification methods to remove impurities
|
|
AU2014240596B2
(en)
|
2013-03-14 |
2018-09-27 |
Amgen Inc. |
Removal of leaked affinity purification ligand
|
|
TWI625390B
(zh)
|
2013-03-14 |
2018-06-01 |
安美基公司 |
用於增加重組蛋白質之甘露糖含量之方法
|
|
US9546203B2
(en)
|
2013-03-14 |
2017-01-17 |
Amgen Inc. |
Aglycosylated Fc-containing polypeptides with cysteine substitutions
|
|
US20140271629A1
(en)
|
2013-03-14 |
2014-09-18 |
Amgen Inc. |
Chrdl-1 antigen binding proteins and methods of treatment
|
|
WO2014144553A1
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Inc. |
Secreted frizzle-related protein 5 (sfrp5) binding proteins and methods of treatment
|
|
EP2970459A2
(de)
|
2013-03-15 |
2016-01-20 |
AbbVie Inc. |
Gegen il-1beta und il-17 gerichtete duale spezifische bindungsproteine
|
|
WO2014144817A2
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Inc. |
Inhibitory polypeptides specific to wnt inhibitors
|
|
TWI828269B
(zh)
|
2013-03-15 |
2024-01-01 |
美商百歐維拉提夫治療公司 |
因子ix多肽調配物
|
|
JP6469644B2
(ja)
|
2013-03-15 |
2019-02-13 |
アムジエン・インコーポレーテツド |
抗ccr7抗原結合タンパク質に関係する方法および組成物
|
|
TWI636064B
(zh)
|
2013-03-15 |
2018-09-21 |
安美基公司 |
人類pac1抗體
|
|
US9481901B2
(en)
|
2013-05-30 |
2016-11-01 |
Amgen Inc. |
Methods for increasing mannose content of recombinant proteins
|
|
SG11201508829QA
(en)
|
2013-05-30 |
2015-12-30 |
Biogen Ma Inc |
Oncostatin m receptor antigen binding proteins
|
|
TWI755763B
(zh)
|
2013-06-04 |
2022-02-21 |
美商再生元醫藥公司 |
藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
|
|
KR20210132232A
(ko)
|
2013-06-21 |
2021-11-03 |
사노피 바이오테크놀로지 |
Il-4r 길항제를 투여함에 의한 비용종증의 치료 방법
|
|
TWI634900B
(zh)
|
2013-07-11 |
2018-09-11 |
再生元醫藥公司 |
藉由投與il-4r抑制劑治療嗜酸性食道炎的方法
|
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
|
CA2923145C
(en)
|
2013-09-05 |
2025-09-16 |
Amgen Inc. |
MOLECULES CONTAINING FCS AND EXHIBITING PREDICTABLE, UNIFORM AND REPRODUCIBLE GLYCOFORM PROFILES
|
|
EP3683232A1
(de)
|
2013-09-13 |
2020-07-22 |
F. Hoffmann-La Roche AG |
Verfahren und zusammensetzungen mit gereinigten rekombinanten polypeptiden
|
|
RU2016107435A
(ru)
|
2013-09-13 |
2017-10-18 |
Дженентек, Инк. |
Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты
|
|
EP3049440B1
(de)
|
2013-09-25 |
2020-03-25 |
Amgen Inc. |
V-c-fc-v-c-antikörper
|
|
ES3030960T3
(en)
|
2013-10-31 |
2025-07-02 |
Amgen Inc |
Use of monensin to regulate glycosylation of recombinant proteins
|
|
WO2015086727A2
(en)
|
2013-12-11 |
2015-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New prognostic method for patients suffering of a cancer
|
|
US8980273B1
(en)
|
2014-07-15 |
2015-03-17 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
|
DE202014010499U1
(de)
|
2013-12-17 |
2015-10-20 |
Kymab Limited |
Targeting von humaner PCSK9 zur Cholesterinbehandlung
|
|
US8986691B1
(en)
|
2014-07-15 |
2015-03-24 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
|
MX376230B
(es)
|
2014-01-13 |
2025-03-07 |
Amgen Inc |
Regulación del metábolismo de ornitina para manipular el contenido de glicoformas ricas en manosa de proteínas recombinantes.
|
|
US10106829B2
(en)
|
2014-01-29 |
2018-10-23 |
Amgen Inc. |
Overexpression of N-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
|
|
BR112016017606A2
(pt)
|
2014-01-29 |
2017-10-10 |
Amgen Inc |
superexpressão de reguladores de via de n-glicosilação para modular a glicosilação de proteínas recombinantes
|
|
AU2015218903B2
(en)
|
2014-02-20 |
2020-10-15 |
Allergan, Inc. |
Complement component C5 antibodies
|
|
IL315136A
(en)
|
2014-02-21 |
2024-10-01 |
Sanofi Biotechnology |
Methods for treating or preventing asthma by administering an il-4rantagonist
|
|
KR20160126054A
(ko)
|
2014-02-27 |
2016-11-01 |
알러간, 인코포레이티드 |
보체 인자 Bb 항체
|
|
KR102927870B1
(ko)
|
2014-02-28 |
2026-02-19 |
리제너론 파아마슈티컬스, 인크. |
Il-4r 길항제의 투여에 의한 피부 감염의 치료 방법
|
|
NO2785538T3
(de)
|
2014-05-07 |
2018-08-04 |
|
|
|
MX377275B
(es)
|
2014-05-16 |
2025-03-07 |
Amgen Inc |
Ensayo para detectar poblaciones celulares linfocitos t colaboradores 1 (th1) y linfocitos t colaboradores (th2).
|
|
SG10202113019XA
(en)
|
2014-06-04 |
2021-12-30 |
Amgen Inc |
Methods for harvesting mammalian cell cultures
|
|
WO2016023916A1
(en)
|
2014-08-12 |
2016-02-18 |
Kymab Limited |
Treatment of disease using ligand binding to targets of interest
|
|
MX2017003247A
(es)
|
2014-09-15 |
2017-11-30 |
Amgen Inc |
Proteina de union a antigenos, bi-especificos del receptor anti-cgrp/receptor pac1 y usos de las mismas.
|
|
WO2016071701A1
(en)
|
2014-11-07 |
2016-05-12 |
Kymab Limited |
Treatment of disease using ligand binding to targets of interest
|
|
WO2016077675A1
(en)
|
2014-11-14 |
2016-05-19 |
Sanofi Biotechnology |
Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist
|
|
US11275090B2
(en)
|
2014-11-19 |
2022-03-15 |
Amgen Inc. |
Quantitation of glycan moiety in recombinant glycoproteins
|
|
PL3227454T3
(pl)
|
2014-12-01 |
2020-07-27 |
Amgen Inc. |
Sposób manipulowania poziomem zawartości glikanów w glikoproteinie
|
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
|
EP3254104B1
(de)
|
2015-02-04 |
2021-08-25 |
Bristol-Myers Squibb Company |
Verfahren zur auswahl therapeutischer moleküle
|
|
SG11201706293XA
(en)
|
2015-02-04 |
2017-09-28 |
Hoffmann La Roche |
Tau antisense oligomers and uses thereof
|
|
WO2016151018A1
(en)
|
2015-03-24 |
2016-09-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method and pharmaceutical composition for use in the treatment of diabetes
|
|
JP6938383B2
(ja)
|
2015-04-02 |
2021-09-22 |
インターベット インターナショナル ベー. フェー. |
イヌインターロイキン4受容体アルファに対する抗体
|
|
EP3286227A2
(de)
|
2015-04-24 |
2018-02-28 |
F. Hoffmann-La Roche AG |
Multispezifische antigenbindende proteine
|
|
TWI728953B
(zh)
|
2015-04-24 |
2021-06-01 |
美商安美基公司 |
治療或預防偏頭痛之方法
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
|
CA2998174A1
(en)
|
2015-09-15 |
2017-03-23 |
Amgen Inc. |
Tetravalent bispecific and tetraspecific antigen binding proteins and uses thereof
|
|
AU2016329001A1
(en)
|
2015-09-22 |
2018-03-29 |
Genentech, Inc. |
Expression of Fc-containing proteins
|
|
WO2017079165A1
(en)
|
2015-11-02 |
2017-05-11 |
Genentech, Inc. |
Methods of making fucosylated and afucosylated forms of a protein
|
|
US10822408B2
(en)
|
2015-12-15 |
2020-11-03 |
Amgen Inc. |
PACAP antibodies and uses thereof
|
|
CR20180378A
(es)
|
2015-12-23 |
2018-12-06 |
Amgen Inc |
Método para tratar o mejorar trastornos metabólicos con proteínas de unión para el receptor peptídico inhibidor gástrico (gipr) en combinación con agosnistas de glp-1
|
|
CN115073581A
(zh)
|
2016-05-04 |
2022-09-20 |
美国安进公司 |
用于扩增t调节性细胞的白细胞介素-2突变蛋白
|
|
KR102435801B1
(ko)
|
2016-07-22 |
2022-08-25 |
암젠 인크 |
Fc-함유 단백질의 정제 방법
|
|
US11771743B2
(en)
|
2016-09-01 |
2023-10-03 |
Regeneron Pharmaceuticals, Inc. |
Methods for preventing or treating allergy by administering an IL-4R antagonist
|
|
US10485844B2
(en)
|
2016-09-22 |
2019-11-26 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating severe atopic dermatitis by administering an IL-4R inhibitor
|
|
ES3064802T3
(en)
|
2016-10-21 |
2026-04-29 |
Amgen Inc |
Pharmaceutical formulations and methods of making the same
|
|
CA3043528A1
(en)
|
2016-11-14 |
2018-05-17 |
Amgen Inc. |
Bispecific or biparatopic antigen binding proteins and uses thereof
|
|
TWI857389B
(zh)
|
2016-12-01 |
2024-10-01 |
美商再生元醫藥公司 |
治療發炎症狀的方法
|
|
EP3567054A4
(de)
|
2017-01-06 |
2021-03-10 |
ABL Bio Inc. |
Anti-alpha-syn-antikörper und verwendung davon
|
|
MX2019008029A
(es)
|
2017-01-06 |
2019-12-11 |
Abl Bio Inc |
Anticuerpo anti-alfa-sinucleina y su uso.
|
|
KR102781241B1
(ko)
|
2017-01-17 |
2025-03-14 |
암젠 인크 |
위 저해 펩타이드 수용체(gipr)에 대한 길항제에 접합된 glp-1 수용체 작용제를 사용하여 대사 장애를 치료 또는 개선하는 방법
|
|
AU2018235928B2
(en)
|
2017-03-14 |
2023-09-21 |
Amgen Inc. |
Control of total afucosylated glycoforms of antibodies produced in cell culture
|
|
CA3059731A1
(en)
|
2017-04-21 |
2018-10-25 |
Kindred Biosciences, Inc. |
Il4/il13 receptor molecule for veterinary use
|
|
JOP20190248A1
(ar)
|
2017-04-21 |
2019-10-20 |
Amgen Inc |
بروتينات ربط مولد ضد trem2 واستخداماته
|
|
JOP20190259A1
(ar)
|
2017-05-31 |
2019-10-31 |
Amgen Inc |
بروتينات ربط مولد ضد مضادة لـ jagged1
|
|
MX2019013919A
(es)
|
2017-06-20 |
2020-01-21 |
Amgen Inc |
Metodo para tratar o mejorar trastornos metabolicos con proteinas de union para el receptor peptidico inhibidor gastrico (gipr) en combinacion con agonistas de glp-1.
|
|
JP7250706B2
(ja)
|
2017-06-21 |
2023-04-03 |
アムジエン・インコーポレーテツド |
胃抑制ペプチド受容体(gipr)に対するアンタゴニスト結合タンパク質/glp-1受容体アゴニスト融合タンパク質を使用した代謝障害の治療又は寛解方法
|
|
US20210228738A1
(en)
|
2017-07-17 |
2021-07-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
|
|
WO2019020480A1
(en)
|
2017-07-24 |
2019-01-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
ANTIBODIES AND PEPTIDES FOR TREATING HCMV RELATED DISEASES
|
|
WO2019028367A1
(en)
|
2017-08-04 |
2019-02-07 |
Regeneron Pharmaceuticals, Inc. |
METHODS OF TREATING ESOPHAGITIS WITH ACTIVE EOSINOPHILES
|
|
FI3661562T3
(fi)
|
2017-08-04 |
2024-12-09 |
Amgen Inc |
Cys-mab:ien konjugointimenetelmä
|
|
EP3703818B1
(de)
|
2017-10-30 |
2023-11-01 |
Sanofi Biotechnology |
Il-4r-antagonisten zur verwendung zur behandlung oder verhinderung von asthma
|
|
CN111886251A
(zh)
|
2017-12-14 |
2020-11-03 |
Abl生物公司 |
抗a-syn/igf1r的双特异性抗体及其用途
|
|
WO2019140216A1
(en)
|
2018-01-12 |
2019-07-18 |
Amgen Inc. |
Pac1 antibodies and uses thereof
|
|
CN119639849A
(zh)
|
2018-03-26 |
2025-03-18 |
美国安进公司 |
细胞培养物中产生的抗体的总去岩藻糖基化糖型
|
|
IL321253A
(en)
|
2018-05-01 |
2025-08-01 |
Amgen Inc |
Antibodies with a modulated glycan profile
|
|
MA52624A
(fr)
|
2018-05-13 |
2021-03-24 |
Regeneron Pharma |
Méthodes de traitement de la dermatite atopique par administration d'un inhibiteur de l'il-4r
|
|
WO2019225777A1
(ko)
|
2018-05-23 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-ror1 항체 및 그 용도
|
|
WO2019225787A1
(ko)
|
2018-05-24 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-b7-h3 항체 및 그 용도
|
|
US20210379146A1
(en)
|
2018-10-04 |
2021-12-09 |
Inserm (Institut National De La Santé Et De La Recherche Médigale) |
Method to restore or improve cognitive functions
|
|
WO2020074005A1
(en)
*
|
2018-10-12 |
2020-04-16 |
Beijing Biocytogen Co., Ltd |
Genetically modified non-human animal with human or chimeric genes
|
|
EP3870601A4
(de)
|
2018-10-25 |
2022-07-13 |
Kindred Biosciences, Inc. |
Il4/il13-rezeptormolekül zur verwendung in der veterinärmedizin
|
|
WO2020123327A1
(en)
|
2018-12-10 |
2020-06-18 |
Amgen Inc. |
Mutated piggybac transposase
|
|
SG11202109002XA
(en)
|
2019-03-21 |
2021-09-29 |
Regeneron Pharma |
Combination of il-4/il-13 pathway inhibitors and plasma cell ablation for treating allergy
|
|
SG11202112926YA
(en)
|
2019-05-30 |
2021-12-30 |
Amgen Inc |
Engineering the hinge region to drive antibody dimerization
|
|
US20220363770A1
(en)
|
2019-06-28 |
2022-11-17 |
Amgen Inc. |
Anti-cgrp receptor/anti-pac1 receptor bispecific antigen binding proteins
|
|
CA3147436A1
(en)
|
2019-07-16 |
2021-01-21 |
Sanofi Biotechnology |
Methods for treating or preventing asthma by administering an il-4r antagonist
|
|
AU2020325021B2
(en)
|
2019-08-05 |
2024-05-30 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R antagonist
|
|
EP4010373A1
(de)
|
2019-08-05 |
2022-06-15 |
Regeneron Pharmaceuticals, Inc. |
Verfahren zur behandlung atopischer dermatitis durch verabreichung eines il-4r-antagonisten
|
|
UY38836A
(es)
|
2019-08-13 |
2021-02-26 |
Amgen Inc |
Muteínas de interleucina-2 para la expansión de células t reguladoras
|
|
AU2020355251A1
(en)
|
2019-09-26 |
2022-04-21 |
Amgen Inc. |
Methods of producing antibody compositions
|
|
EP4054590A1
(de)
|
2019-11-04 |
2022-09-14 |
Amgen Inc. |
Verfahren zur behandlung von leukämie
|
|
WO2021092355A1
(en)
|
2019-11-08 |
2021-05-14 |
Amgen Inc. |
Engineering charge pair mutations for pairing of hetero-igg molecules
|
|
CA3160438A1
(en)
|
2019-11-19 |
2021-05-27 |
Amgen Inc. |
Novel multispecific antibody format
|
|
CN114867749A
(zh)
|
2019-12-17 |
2022-08-05 |
安进公司 |
用于疗法中的双重白介素-2/tnf受体激动剂
|
|
JP2023507323A
(ja)
|
2019-12-20 |
2023-02-22 |
アムジエン・インコーポレーテツド |
固形腫瘍の治療のためのメソセリン標的化cd40アゴニスト多重特異性抗体コンストラクト
|
|
EP4153736A4
(de)
|
2020-05-19 |
2025-10-01 |
Univ North Carolina State |
Zusammensetzungen und verfahren zur herstellung von menschlichen milcholigosacchariden
|
|
WO2021247892A1
(en)
|
2020-06-04 |
2021-12-09 |
Amgen Inc. |
Assessment of cleaning procedures of a biotherapeutic manufacturing process
|
|
JP2023538897A
(ja)
|
2020-08-20 |
2023-09-12 |
アムジエン・インコーポレーテツド |
Fab領域中に非標準的なジスルフィドを有する抗原結合タンパク質
|
|
US20230374162A1
(en)
|
2020-10-07 |
2023-11-23 |
Amgen Inc. |
Rational selection of building blocks for the assembly of multispecific antibodies
|
|
AU2021360897A1
(en)
|
2020-10-15 |
2023-05-25 |
Amgen Inc. |
Relative unpaired glycans in antibody production methods
|
|
TW202233660A
(zh)
|
2020-10-30 |
2022-09-01 |
美商安進公司 |
過表現胰島素樣生長因子受體突變體以調節igf補充
|
|
US20240002545A1
(en)
|
2020-11-10 |
2024-01-04 |
Amgen Inc. |
Novel linkers of multispecific antigen binding domains
|
|
CA3216559A1
(en)
|
2021-04-20 |
2022-10-27 |
Amgen Inc. |
Balanced charge distribution in electrostatic steering of chain pairing in multi-specific and monovalent igg molecule assembly
|
|
WO2022232376A1
(en)
|
2021-04-29 |
2022-11-03 |
Amgen Inc. |
Methods for reducing low molecular weight species of recombinantly-produced proteins
|
|
AR126089A1
(es)
|
2021-06-07 |
2023-09-13 |
Amgen Inc |
Uso de fucosidasa para controlar el nivel de afucosilación de proteínas glucosiladas
|
|
EP4351722A1
(de)
|
2021-06-10 |
2024-04-17 |
Amgen Inc. |
Manipulierte nrg-1-varianten mit verbesserter selektivität gegenüber erbb4 aber nicht gegen erbb3
|
|
TW202328442A
(zh)
|
2021-09-10 |
2023-07-16 |
美商安進公司 |
平臺宿主對igf—培養基之適應
|
|
WO2023059607A1
(en)
|
2021-10-05 |
2023-04-13 |
Amgen Inc. |
Fc-gamma receptor ii binding and glycan content
|
|
EP4457342A1
(de)
|
2021-12-29 |
2024-11-06 |
Bristol-Myers Squibb Company |
Erzeugung von landefeldzelllinien
|
|
JP2025507049A
(ja)
|
2022-03-09 |
2025-03-13 |
アムジエン・インコーポレーテツド |
最適化されたトランスフェクションプロトコール
|
|
EP4493590A1
(de)
|
2022-03-16 |
2025-01-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Neues verfahren zur behandlung von infektionskrankheiten
|
|
IL316264A
(en)
|
2022-05-02 |
2024-12-01 |
Regeneron Pharma |
Antibody formulations against interleukin-4 receptor (IL-4R)
|
|
WO2023215750A2
(en)
|
2022-05-02 |
2023-11-09 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing lipase activity
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
EP4406973A1
(de)
|
2023-01-27 |
2024-07-31 |
Fundació Privada Institut de Recerca de la SIDA-Caixa |
Antikörper und verwendungen davon zur behandlung von infektionen durch eingehüllte viren
|
|
AU2024256160A1
(en)
|
2023-04-20 |
2025-10-02 |
Amgen Inc. |
Methods of determining relative unpaired glycan content
|
|
AU2024307352A1
(en)
|
2023-06-27 |
2025-12-11 |
Amgen Inc. |
Charge pair mutations to enable correct heavy-light chain pairing
|
|
KR20260042226A
(ko)
|
2023-07-21 |
2026-03-30 |
암젠 인크 |
선택 가능한 마커 발현을 유도하는 프로모터의 조합을 포함하는 벡터
|
|
AU2024325342A1
(en)
|
2023-08-14 |
2026-02-26 |
Amgen Inc. |
Methods for reducing yellow color
|
|
IL327356A
(en)
|
2023-10-18 |
2026-05-01 |
Amgen Inc |
Quantitative assessment of mRNA transcript levels using DDPCR for initial pool characterization and evaluation of single-cell clones in the cell line development process
|
|
AU2024373307A1
(en)
|
2023-11-02 |
2026-05-14 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing lipase activity using stress
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
TW202546234A
(zh)
|
2024-01-19 |
2025-12-01 |
美商安進公司 |
具有兩個輕鏈拷貝的表現載體系統
|
|
WO2025155774A2
(en)
|
2024-01-19 |
2025-07-24 |
Amgen Inc. |
Vector engineering strategies to enhance volumetric productivity and decrease impurity formation across a diverse set of modalities
|
|
WO2025160161A1
(en)
|
2024-01-23 |
2025-07-31 |
Amgen Inc. |
Methods for modulating monoclonal antibody charge variants
|
|
WO2025184493A1
(en)
|
2024-02-29 |
2025-09-04 |
Amgen Inc. |
Dual selection expression vector systems for multi-chain biologics
|
|
WO2025199030A1
(en)
|
2024-03-18 |
2025-09-25 |
Amgen Inc. |
Glp-1 receptor agonists and their medical use
|
|
WO2026090253A1
(en)
|
2024-10-23 |
2026-04-30 |
Amgen Inc. |
Methods of determining glycan pairing content
|