ATE153341T1 - 5-o-desosaminylerythronolid derivate - Google Patents

5-o-desosaminylerythronolid derivate

Info

Publication number
ATE153341T1
ATE153341T1 AT93900447T AT93900447T ATE153341T1 AT E153341 T1 ATE153341 T1 AT E153341T1 AT 93900447 T AT93900447 T AT 93900447T AT 93900447 T AT93900447 T AT 93900447T AT E153341 T1 ATE153341 T1 AT E153341T1
Authority
AT
Austria
Prior art keywords
moiety
optionally substituted
hydrogen
linkage
desosaminylerythronolide
Prior art date
Application number
AT93900447T
Other languages
English (en)
Inventor
Toshifumi Taisho Pharmac Asaka
Yoko Taisho Pharmaceuti Misawa
Masato Taisho Pharma Kashimura
Shigeo Taisho Pharmac Morimoto
Katsuo Taisho Pharmac Hatayama
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE153341T1 publication Critical patent/ATE153341T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT93900447T 1991-12-27 1992-12-25 5-o-desosaminylerythronolid derivate ATE153341T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP34682691 1991-12-27
JP19936892 1992-07-27
JP27986792 1992-10-19

Publications (1)

Publication Number Publication Date
ATE153341T1 true ATE153341T1 (de) 1997-06-15

Family

ID=27327638

Family Applications (2)

Application Number Title Priority Date Filing Date
AT93900447T ATE153341T1 (de) 1991-12-27 1992-12-25 5-o-desosaminylerythronolid derivate
AT93900446T ATE149508T1 (de) 1991-12-27 1992-12-25 5-0-desosaminylerrythronolide-derivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT93900446T ATE149508T1 (de) 1991-12-27 1992-12-25 5-0-desosaminylerrythronolide-derivate

Country Status (10)

Country Link
US (2) US5523399A (de)
EP (2) EP0619320B1 (de)
JP (2) JP3132002B2 (de)
KR (2) KR100265916B1 (de)
AT (2) ATE153341T1 (de)
AU (2) AU663145B2 (de)
CA (2) CA2126665A1 (de)
DE (2) DE69217989T2 (de)
ES (2) ES2104118T3 (de)
WO (2) WO1993013115A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631355A (en) * 1992-04-22 1997-05-20 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide a derivatives
KR960700258A (ko) * 1993-01-26 1996-01-19 우에하라 아키라 5-0-데소사미닐에리쓰로노라이드 유도체
KR970704455A (ko) * 1994-08-12 1997-09-06 우에하라 아끼라 인터류킨 5 생성 억제제(Interleukin 5 Production Inhibitor)
FR2738571B1 (fr) * 1995-09-11 1997-10-17 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
FR2739620B1 (fr) * 1995-10-09 1997-12-19 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
USRE38426E1 (en) 1995-10-09 2004-02-10 Aventis Pharma S.A. 5-O-deosaminyl 6-O-methyl erythronolide A derivatives, preparation method therefor and use thereof for preparing biologically active materials
US6274715B1 (en) 1995-11-08 2001-08-14 Abbott Laboratories Tricyclic erythromycin derivatives
KR19990067333A (ko) * 1995-11-08 1999-08-16 스티븐 에프. 웨인스톡 에리트로마이신 a 및 b의 3-데옥시-3-데스클라디노즈 유도체
ES2218604T3 (es) * 1995-11-08 2004-11-16 Abbott Laboratories Derivados triciclicos de eritromicina.
US5747466A (en) * 1995-11-08 1998-05-05 Abbott Laboratories 3-deoxy-3-descladinose derivatives of erythromycins A and B
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
SK285534B6 (sk) * 1996-09-04 2007-03-01 Abbott Laboratories 6-O-substituované ketolidy s antibakteriálnou aktivitou, farmaceutická kompozícia s ich obsahom, ich použitie a spôsob ich prípravy
US5804565A (en) * 1996-09-24 1998-09-08 Taisho Pharmaceutical Co., Ltd. Erythromycin A derivatives
CA2272620A1 (en) 1996-11-27 1998-06-04 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO1998042720A1 (fr) * 1997-03-24 1998-10-01 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
US6169168B1 (en) 1997-10-29 2001-01-02 Taisho Pharmaceuticals Co., Ltd. Erythromycin A derivatives
AU9645998A (en) * 1997-10-29 1999-05-17 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO1999021870A1 (en) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Erythromycin a 11, 12-carbamate derivatives
AU1504899A (en) * 1997-12-11 1999-06-28 Hokuriku Seiyaku Co. Ltd Erythromycin derivatives
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
FR2777282B1 (fr) * 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6395710B1 (en) * 1999-04-16 2002-05-28 Kosan Biosciences, Inc. Macrolide antiinfective agents
IL145739A0 (en) * 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
US6420535B1 (en) * 1999-06-07 2002-07-16 Abbott Laboratories 6-O-carbamate ketolide derivatives
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
EP1146051A3 (de) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A-Derivate
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
WO2005012322A1 (ja) * 2003-08-05 2005-02-10 Taisho Pharmaceutical Co., Ltd. エリスロマイシンａ １１，１２−サイクリックカーボネートの製造方法
WO2005030227A1 (en) 2003-09-23 2005-04-07 Enanta Pharmaceuticals, Inc. 9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
EP1781679A1 (de) * 2004-07-28 2007-05-09 Ranbaxy Laboratories Limited Antibakterielle mittel
US7402568B2 (en) 2004-09-29 2008-07-22 Enanta Pharmaceuticals, Inc. Bicyclic 9a-azalide derivatives
EP2233493A1 (de) 2004-12-21 2010-09-29 Pfizer Products Inc. Makrolide
US7271155B2 (en) 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
WO2006077501A2 (en) * 2005-01-13 2006-07-27 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Decladinosyl-macrolides with anti-inflammatory activity
WO2009019868A1 (ja) 2007-08-06 2009-02-12 Taisho Pharmaceutical Co., Ltd. １０ａ、１２位架橋型１０ａ－アザライド化合物
EP2188281A1 (de) * 2007-08-10 2010-05-26 Y's Therapeutics Co, Ltd. Modulation von immunreaktionen durch verabreichung von roxithromycin oder dessen derivat
WO2009139181A1 (ja) 2008-05-15 2009-11-19 大正製薬株式会社 ４員環構造を有する１０ａ－アザライド化合物
US8143369B2 (en) * 2009-06-02 2012-03-27 International Business Machines Corporation Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof
CN101863941A (zh) * 2010-06-03 2010-10-20 武汉大学 3-氧-取代的6,11-二-氧-甲基红霉素a的衍生物
CN104961785B (zh) * 2015-06-19 2019-01-11 北京理工大学 一种新型酰内酯衍生物及其制备方法
IL303173A (en) 2023-05-23 2024-12-01 Yeda Res & Dev Active macrolide antibiotic compounds against pathogens

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923784A (en) * 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
US4518590A (en) * 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
GB8521402D0 (en) * 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
KR880009960A (ko) * 1987-02-24 1988-10-06 데이빗 로버츠 화학적 화합물
JPH0196190A (ja) * 1987-10-07 1989-04-14 Toyo Jozo Co Ltd ６−０−アルキル−エリスロマイシンａ　サイクリック１１，１２−カーボネート
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE69217989T2 (de) 1997-06-12
EP0619319A1 (de) 1994-10-12
US5631354A (en) 1997-05-20
KR940703842A (ko) 1994-12-12
ES2104118T3 (es) 1997-10-01
AU667334B2 (en) 1996-03-21
DE69219900D1 (de) 1997-06-26
KR100265916B1 (ko) 2000-09-15
CA2126665A1 (en) 1993-07-08
AU3172793A (en) 1993-07-28
CA2126664A1 (en) 1993-07-08
WO1993013115A1 (fr) 1993-07-08
US5523399A (en) 1996-06-04
ATE149508T1 (de) 1997-03-15
WO1993013116A1 (fr) 1993-07-08
EP0619320B1 (de) 1997-05-21
KR100266183B1 (ko) 2000-09-15
AU663145B2 (en) 1995-09-28
EP0619320A4 (de) 1994-11-02
DE69219900T2 (de) 1997-09-11
DE69217989D1 (de) 1997-04-10
EP0619319A4 (de) 1994-11-02
JP3099366B2 (ja) 2000-10-16
EP0619319B1 (de) 1997-03-05
KR940703841A (ko) 1994-12-12
JP3132002B2 (ja) 2001-02-05
ES2101290T3 (es) 1997-07-01
AU3172893A (en) 1993-07-28
EP0619320A1 (de) 1994-10-12

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties