ATE157870T1 - Ophthalmische zusammensetzung enthaltend ein 1,5- benzoxathiepin-derivat zur behandlung von glaukoma - Google Patents
Ophthalmische zusammensetzung enthaltend ein 1,5- benzoxathiepin-derivat zur behandlung von glaukomaInfo
- Publication number
- ATE157870T1 ATE157870T1 AT95100934T AT95100934T ATE157870T1 AT E157870 T1 ATE157870 T1 AT E157870T1 AT 95100934 T AT95100934 T AT 95100934T AT 95100934 T AT95100934 T AT 95100934T AT E157870 T1 ATE157870 T1 AT E157870T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally substituted
- hydrogen
- treatment
- ophthalmic composition
- benzoxathiepine
- Prior art date
Links
- 208000010412 Glaucoma Diseases 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 208000030533 eye disease Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 125000005346 substituted cycloalkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP747094 | 1994-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE157870T1 true ATE157870T1 (de) | 1997-09-15 |
Family
ID=11666688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95100934T ATE157870T1 (de) | 1994-01-27 | 1995-01-25 | Ophthalmische zusammensetzung enthaltend ein 1,5- benzoxathiepin-derivat zur behandlung von glaukoma |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5538974A (de) |
| EP (1) | EP0667156B1 (de) |
| KR (1) | KR950032169A (de) |
| CN (1) | CN1116928A (de) |
| AT (1) | ATE157870T1 (de) |
| CA (1) | CA2141176A1 (de) |
| DE (1) | DE69500660T2 (de) |
| ES (1) | ES2106573T3 (de) |
| TW (1) | TW316235B (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960579B1 (en) * | 1998-05-19 | 2005-11-01 | Alcon Manufacturing, Ltd. | Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders |
| AU755119B2 (en) | 1998-09-18 | 2002-12-05 | Alcon Laboratories, Inc. | Serotonergic 5HT2 agonists for treating glaucoma |
| DE60117247D1 (de) * | 2000-03-31 | 2006-04-20 | Purdue Research Foundation West Lafayette | Phosphoramidat-prodrugs |
| FR2822467B1 (fr) * | 2001-03-22 | 2003-12-12 | Pf Medicament | Derives benzoxathiepines et leur utilisation comme medicaments |
| JP2005511764A (ja) * | 2001-12-14 | 2005-04-28 | アルコン，インコーポレイテッド | 緑内障の処置のためのアミノアルキルベンゾフラン−５−オール化合物 |
| TW593302B (en) * | 2001-12-20 | 2004-06-21 | Alcon Inc | Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma |
| DK1534391T3 (da) * | 2002-07-19 | 2007-06-11 | Biovitrum Ab | Nye piperazinyl-pyrazinonderivater til behandling af 5-HT2A-recptor-relaterede forstyrrelser |
| JP2006501245A (ja) * | 2002-08-30 | 2006-01-12 | アルコン，インコーポレイテッド | 置換された５−クロマン−５−イル−エチルアミン化合物および緑内障の治療のためのその使用 |
| BR0316775A (pt) * | 2002-12-13 | 2005-11-01 | Alcon Inc | Novos análogos de benzopirano e seu uso para o tratamento de glaucoma |
| US20060286173A1 (en) * | 2003-08-20 | 2006-12-21 | Kazuhito Yamada | Drug delivery system for sub-tenon s capsule adminstration of fine grains |
| US7476687B2 (en) * | 2003-11-26 | 2009-01-13 | Alcon, Inc. | Substituted furo[2,3-g]indazoles for the treatment of glaucoma |
| US7338972B1 (en) | 2003-12-15 | 2008-03-04 | Alcon, Inc. | Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma |
| AR046890A1 (es) * | 2003-12-15 | 2005-12-28 | Alcon Inc | [1,4] oxazino [2,3-g] indazoles sustituidos para el tratamiento del glaucoma. |
| US7129257B1 (en) * | 2003-12-15 | 2006-10-31 | Alcon, Inc. | Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma |
| US20050276867A1 (en) * | 2004-06-09 | 2005-12-15 | Allergan, Inc. | Stabilized compositions comprising a therapeutically active agent and an oxidizing preservative |
| WO2006062839A1 (en) * | 2004-12-08 | 2006-06-15 | Alcon, Inc. | Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma |
| TW200744567A (en) * | 2005-09-23 | 2007-12-16 | Alcon Inc | Phenylethylamine analogs and their use for treating glaucoma |
| WO2007149728A2 (en) * | 2006-06-20 | 2007-12-27 | Alcon Research, Ltd. | Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma |
| EP2095713A1 (de) * | 2006-10-20 | 2009-09-02 | Limited Liability Company "Mitotechnology" | Zusammensetzung für die regeneration und stimulation des wachstums von pflanzen und für die anpassung von pflanzen an unterschiedliche stressfaktoren |
| EA200900582A1 (ru) * | 2006-10-20 | 2009-08-28 | Общество С Ограниченной Ответственностью "Митотехнология" | Фармацевтические композиции для профилактики и лечения глазных патологий |
| EP2145623A4 (de) * | 2007-01-29 | 2010-10-27 | Ltd Liability Company Mitotech | Pharmazeutische und kosmetische zusammensetzungen zur beschleunigten heilung von wunden und anderen oberflächenschäden |
| WO2008094062A1 (en) | 2007-01-29 | 2008-08-07 | Limited Liability Company 'mitotechnology' | Pharmaceutical compositions useful for preventing and treating oncological diseases |
| EA016723B1 (ru) * | 2007-02-27 | 2012-07-30 | Дели Инститьют Оф Фармасьютикал Сайнсиз Энд Рисерч (Дипсар) | Синергетическая травяная композиция, применяемая при глаукоме, и способ ее получения |
| WO2008127138A1 (fr) * | 2007-04-11 | 2008-10-23 | Limited Liability Company 'mitotechnology' | Composition visant à ralentir le vieillissement et à allonger la durée de vie de l'organisme et utilisation de cette composition |
| US8518915B2 (en) | 2007-06-29 | 2013-08-27 | Mitotech Sa | Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases |
| US9308214B2 (en) | 2008-11-12 | 2016-04-12 | Mitotech S.A. | Method for moderately increasing the proton conductivity of biological membranes with the aid of mitochondria-targeted delocalized cations |
| EA025414B1 (ru) * | 2009-06-10 | 2016-12-30 | Общество С Ограниченной Ответственностью "Митотех" | Фармацевтическая композиция для применения в медицинской и ветеринарной офтальмологии |
| MX2012005356A (es) | 2009-11-13 | 2013-01-29 | Obschestvo S Ogranichennoi Otvetstvennostyu Mitotekh | Substancias farmaceuticas basadas en antioxidantes dirigidos a mitocondria. |
| CN103260466B (zh) | 2010-12-20 | 2016-08-17 | 高露洁-棕榄公司 | 含有亲水性活性物质、疏水性结构化剂和油载体的明胶包囊的口腔护理组合物 |
| ES2704064T3 (es) | 2011-06-03 | 2019-03-14 | Mitotech Sa | Formulaciones orales de antioxidantes dirigidos mitocondrialmente y su preparación y uso |
| CN112439071B (zh) * | 2019-09-04 | 2022-05-20 | 武汉科福新药有限责任公司 | 透皮促渗组合物及其在噻吗洛尔制剂中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK166779B1 (da) * | 1983-12-14 | 1993-07-12 | Takeda Chemical Industries Ltd | 1,5-benzoxatiepinderivater eller farmaceutisk acceptable salte deraf, samt farmaceutisk praeparat indeholdende en saadan forbindelse |
| EP0229467A1 (de) * | 1985-12-10 | 1987-07-22 | Takeda Chemical Industries, Ltd. | 1,5-Benzoxathiepin-Derivate, deren Herstellung und Verwendung |
-
1995
- 1995-01-24 US US08/378,244 patent/US5538974A/en not_active Expired - Fee Related
- 1995-01-25 ES ES95100934T patent/ES2106573T3/es not_active Expired - Lifetime
- 1995-01-25 TW TW084100643A patent/TW316235B/zh active
- 1995-01-25 DE DE69500660T patent/DE69500660T2/de not_active Expired - Fee Related
- 1995-01-25 EP EP95100934A patent/EP0667156B1/de not_active Expired - Lifetime
- 1995-01-25 AT AT95100934T patent/ATE157870T1/de not_active IP Right Cessation
- 1995-01-26 CA CA002141176A patent/CA2141176A1/en not_active Abandoned
- 1995-01-27 KR KR1019950001542A patent/KR950032169A/ko not_active Withdrawn
- 1995-01-27 CN CN95100372A patent/CN1116928A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2106573T3 (es) | 1997-11-01 |
| DE69500660D1 (de) | 1997-10-16 |
| DE69500660T2 (de) | 1998-02-26 |
| CA2141176A1 (en) | 1995-07-28 |
| CN1116928A (zh) | 1996-02-21 |
| EP0667156B1 (de) | 1997-09-10 |
| EP0667156A1 (de) | 1995-08-16 |
| KR950032169A (ko) | 1995-12-20 |
| TW316235B (de) | 1997-09-21 |
| US5538974A (en) | 1996-07-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |