ATE159986T1 - Verfahren zum kategorisieren von nukleotidsequenz-populationen - Google Patents
Verfahren zum kategorisieren von nukleotidsequenz-populationenInfo
- Publication number
- ATE159986T1 ATE159986T1 AT93916049T AT93916049T ATE159986T1 AT E159986 T1 ATE159986 T1 AT E159986T1 AT 93916049 T AT93916049 T AT 93916049T AT 93916049 T AT93916049 T AT 93916049T AT E159986 T1 ATE159986 T1 AT E159986T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- categorizing
- nucleotide sequence
- sequences
- date jan
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 title abstract 2
- 239000012082 adaptor molecule Substances 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
- F02B75/00—Other engines
- F02B75/02—Engines characterised by their cycles, e.g. six-stroke
- F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
- F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929214873A GB9214873D0 (en) | 1992-07-13 | 1992-07-13 | Process for categorising nucleotide sequence populations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE159986T1 true ATE159986T1 (de) | 1997-11-15 |
Family
ID=10718632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93916049T ATE159986T1 (de) | 1992-07-13 | 1993-07-13 | Verfahren zum kategorisieren von nukleotidsequenz-populationen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5728524A (de) |
| EP (1) | EP0650528B1 (de) |
| JP (1) | JP3251291B2 (de) |
| AT (1) | ATE159986T1 (de) |
| AU (1) | AU686563B2 (de) |
| CA (1) | CA2139944A1 (de) |
| DE (1) | DE69315074T2 (de) |
| GB (1) | GB9214873D0 (de) |
| IL (1) | IL106316A0 (de) |
| WO (1) | WO1994001582A1 (de) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100267023A1 (en) * | 1992-09-24 | 2010-10-21 | Keygene N.V. | Selective restriction fragment amplification: fingerprinting |
| GB9401200D0 (en) * | 1994-01-21 | 1994-03-16 | Medical Res Council | Sequencing of nucleic acids |
| US5512458A (en) * | 1994-02-25 | 1996-04-30 | W. R. Grace & Co.-Conn. | Method of using mobile priming sites for DNA sequencing |
| AU1566895A (en) * | 1994-02-25 | 1995-09-11 | Amicon, Inc. | Method of using mobile priming sites for dna sequencing |
| US5552278A (en) * | 1994-04-04 | 1996-09-03 | Spectragen, Inc. | DNA sequencing by stepwise ligation and cleavage |
| US5714330A (en) * | 1994-04-04 | 1998-02-03 | Lynx Therapeutics, Inc. | DNA sequencing by stepwise ligation and cleavage |
| JP3612092B2 (ja) * | 1994-09-07 | 2005-01-19 | 株式会社日立製作所 | Dnaの分離・分取法及びその解析法 |
| US6013445A (en) * | 1996-06-06 | 2000-01-11 | Lynx Therapeutics, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
| USRE43097E1 (en) | 1994-10-13 | 2012-01-10 | Illumina, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
| US5604097A (en) * | 1994-10-13 | 1997-02-18 | Spectragen, Inc. | Methods for sorting polynucleotides using oligonucleotide tags |
| GB2295011A (en) * | 1994-11-10 | 1996-05-15 | Unilever Plc | Selection of DNA markers using adaptor molecules |
| AU4962396A (en) * | 1994-12-23 | 1996-09-18 | Amicon, Inc. | Method of using mobile priming sites for dna sequencing |
| EP0721987A1 (de) * | 1995-01-16 | 1996-07-17 | Keygene N.V. | Amplifikation von einfachen Sequenz-Wiederholungen |
| DE69621507T2 (de) * | 1995-03-28 | 2003-01-09 | Japan Science And Technology Corp., Kawaguchi | Verfahren zur molekularen Indexierung von Genen unter Verwendung von Restriktionsenzymen |
| US5750341A (en) * | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| US5712126A (en) * | 1995-08-01 | 1998-01-27 | Yale University | Analysis of gene expression by display of 3-end restriction fragments of CDNA |
| US5972693A (en) * | 1995-10-24 | 1999-10-26 | Curagen Corporation | Apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing |
| US5763175A (en) * | 1995-11-17 | 1998-06-09 | Lynx Therapeutics, Inc. | Simultaneous sequencing of tagged polynucleotides |
| AU2264197A (en) | 1996-02-09 | 1997-08-28 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Restriction display (rd-pcr) of differentially expressed mrnas |
| US6852487B1 (en) | 1996-02-09 | 2005-02-08 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| EP2369007B1 (de) | 1996-05-29 | 2015-07-29 | Cornell Research Foundation, Inc. | Erkennung von Nukleinsäuresequenz-Unterschieden mittels der gleichzeitigen Ligaseerkennungs- und Polymerasekettenreaktion |
| GB9618544D0 (en) | 1996-09-05 | 1996-10-16 | Brax Genomics Ltd | Characterising DNA |
| US5994068A (en) * | 1997-03-11 | 1999-11-30 | Wisconsin Alumni Research Foundation | Nucleic acid indexing |
| JP2002503954A (ja) | 1997-04-01 | 2002-02-05 | グラクソ、グループ、リミテッド | 核酸増幅法 |
| US5888737A (en) * | 1997-04-15 | 1999-03-30 | Lynx Therapeutics, Inc. | Adaptor-based sequence analysis |
| GB9707980D0 (en) * | 1997-04-21 | 1997-06-11 | Brax Genomics Ltd | Characterising DNA |
| GB9714716D0 (en) | 1997-07-11 | 1997-09-17 | Brax Genomics Ltd | Characterising nucleic acids |
| WO1999002725A1 (en) * | 1997-07-11 | 1999-01-21 | Brax Group Limited | Categorising nucleic acid |
| US6312904B1 (en) | 1997-07-11 | 2001-11-06 | Xzillion Gmbh & Co. Kg | Characterizing nucleic acid |
| DE19806431C1 (de) | 1998-02-17 | 1999-10-14 | Novartis Ag | Neues Verfahren zur Identifikation und Charakterisierung von mRNA-Molekülen |
| US6054276A (en) * | 1998-02-23 | 2000-04-25 | Macevicz; Stephen C. | DNA restriction site mapping |
| US6136537A (en) * | 1998-02-23 | 2000-10-24 | Macevicz; Stephen C. | Gene expression analysis |
| US6232067B1 (en) * | 1998-08-17 | 2001-05-15 | The Perkin-Elmer Corporation | Adapter directed expression analysis |
| US6703228B1 (en) | 1998-09-25 | 2004-03-09 | Massachusetts Institute Of Technology | Methods and products related to genotyping and DNA analysis |
| EP1001037A3 (de) * | 1998-09-28 | 2003-10-01 | Whitehead Institute For Biomedical Research | Vorselektion und Isolierung eines Einzelnukleotidpolymorphismus |
| US8367322B2 (en) | 1999-01-06 | 2013-02-05 | Cornell Research Foundation, Inc. | Accelerating identification of single nucleotide polymorphisms and alignment of clones in genomic sequencing |
| US6534293B1 (en) | 1999-01-06 | 2003-03-18 | Cornell Research Foundation, Inc. | Accelerating identification of single nucleotide polymorphisms and alignment of clones in genomic sequencing |
| EP1196554B1 (de) | 1999-03-18 | 2009-02-25 | Complete Genomics AS | Methoden zur klonierung und herstelung von kettenfragmenten mit lesbarem inhalt an information |
| AU3444300A (en) * | 1999-03-24 | 2000-10-09 | Clatterbridge Cancer Research Trust | Genetic analysis |
| JP2002540802A (ja) * | 1999-04-06 | 2002-12-03 | イェール ユニバーシティ | 配列標識の固定されたアドレス分析 |
| WO2001012855A2 (en) * | 1999-08-13 | 2001-02-22 | Yale University | Binary encoded sequence tags |
| AU2001232140A1 (en) * | 2000-02-17 | 2001-08-27 | Complete Genomics As | A method of mapping restriction endonuclease cleavage sites |
| AU6052001A (en) | 2000-03-29 | 2001-10-08 | Ct For The Applic Of Molecular | Methods for genotyping by hybridization analysis |
| US6468749B1 (en) * | 2000-03-30 | 2002-10-22 | Quark Biotech, Inc. | Sequence-dependent gene sorting techniques |
| DE10024171A1 (de) * | 2000-05-17 | 2001-12-20 | Basf Lynx Bioscience Ag | Neuronale Serin-Threonin-Protein-Kinase |
| WO2002059357A2 (en) * | 2001-01-24 | 2002-08-01 | Genomic Expression Aps | Assay and kit for analyzing gene expression |
| US6949340B2 (en) | 2001-03-28 | 2005-09-27 | Creative Mines Llc | Optical phase modulator |
| US7141371B2 (en) * | 2002-09-06 | 2006-11-28 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Methods for detecting and localizing DNA mutations by microarray |
| CA2513899C (en) * | 2003-01-29 | 2013-03-26 | 454 Corporation | Methods of amplifying and sequencing nucleic acids |
| US7575865B2 (en) * | 2003-01-29 | 2009-08-18 | 454 Life Sciences Corporation | Methods of amplifying and sequencing nucleic acids |
| CN103396933B (zh) | 2003-02-26 | 2016-04-20 | 凯利达基因组股份有限公司 | 通过杂交进行的随机阵列dna分析 |
| FR2852605B1 (fr) * | 2003-03-18 | 2012-11-30 | Commissariat Energie Atomique | Procede de preparation de fragments d'adn et ses applications |
| EP1623996A1 (de) * | 2004-08-06 | 2006-02-08 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Verbessertes Verfahren zur Auswahl eines Proteins von einer Bibliothek |
| GB0422551D0 (en) * | 2004-10-11 | 2004-11-10 | Univ Liverpool | Labelling and sequencing of nucleic acids |
| US20060160102A1 (en) | 2005-01-18 | 2006-07-20 | Hossein Fakhrai-Rad | Identification of rare alleles by enzymatic enrichment of mismatched heteroduplexes |
| US20060240443A1 (en) * | 2005-04-20 | 2006-10-26 | Combimatrix Corporation | Microarray-based single nucleotide polymorphism, sequencing, and gene expression assay method |
| WO2006122215A2 (en) | 2005-05-10 | 2006-11-16 | State Of Oregon Acting By & Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Methods of mapping polymorphisms and polymorphism microarrays |
| EP3257949A1 (de) | 2005-06-15 | 2017-12-20 | Complete Genomics Inc. | Nukleinsäureanalyse durch zufällige mischungen von nichtüberlappenden fragmenten |
| CA2624896C (en) | 2005-10-07 | 2017-11-07 | Callida Genomics, Inc. | Self-assembled single molecule arrays and uses thereof |
| US7960104B2 (en) * | 2005-10-07 | 2011-06-14 | Callida Genomics, Inc. | Self-assembled single molecule arrays and uses thereof |
| US20070168197A1 (en) * | 2006-01-18 | 2007-07-19 | Nokia Corporation | Audio coding |
| CN101432439B (zh) * | 2006-02-24 | 2013-07-24 | 考利达基因组股份有限公司 | Dna阵列上的高通量基因组测序 |
| SG170028A1 (en) * | 2006-02-24 | 2011-04-29 | Callida Genomics Inc | High throughput genome sequencing on dna arrays |
| US20090002703A1 (en) * | 2006-08-16 | 2009-01-01 | Craig Edward Parman | Methods and systems for quantifying isobaric labels and peptides |
| US7910354B2 (en) * | 2006-10-27 | 2011-03-22 | Complete Genomics, Inc. | Efficient arrays of amplified polynucleotides |
| US20090111706A1 (en) * | 2006-11-09 | 2009-04-30 | Complete Genomics, Inc. | Selection of dna adaptor orientation by amplification |
| US20080221832A1 (en) * | 2006-11-09 | 2008-09-11 | Complete Genomics, Inc. | Methods for computing positional base probabilities using experminentals base value distributions |
| US8124336B2 (en) * | 2007-09-26 | 2012-02-28 | Population Genetics Technologies Ltd | Methods and compositions for reducing the complexity of a nucleic acid sample |
| US8951731B2 (en) * | 2007-10-15 | 2015-02-10 | Complete Genomics, Inc. | Sequence analysis using decorated nucleic acids |
| US7897344B2 (en) * | 2007-11-06 | 2011-03-01 | Complete Genomics, Inc. | Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs |
| US8298768B2 (en) * | 2007-11-29 | 2012-10-30 | Complete Genomics, Inc. | Efficient shotgun sequencing methods |
| US8518640B2 (en) * | 2007-10-29 | 2013-08-27 | Complete Genomics, Inc. | Nucleic acid sequencing and process |
| US8415099B2 (en) | 2007-11-05 | 2013-04-09 | Complete Genomics, Inc. | Efficient base determination in sequencing reactions |
| WO2009061840A1 (en) * | 2007-11-05 | 2009-05-14 | Complete Genomics, Inc. | Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation |
| US8592150B2 (en) | 2007-12-05 | 2013-11-26 | Complete Genomics, Inc. | Methods and compositions for long fragment read sequencing |
| WO2009094583A1 (en) * | 2008-01-23 | 2009-07-30 | Complete Genomics, Inc. | Methods and compositions for preventing bias in amplification and sequencing reactions |
| WO2009097368A2 (en) * | 2008-01-28 | 2009-08-06 | Complete Genomics, Inc. | Methods and compositions for efficient base calling in sequencing reactions |
| WO2009132028A1 (en) * | 2008-04-21 | 2009-10-29 | Complete Genomics, Inc. | Array structures for nucleic acid detection |
| WO2010133972A1 (en) | 2009-05-22 | 2010-11-25 | Population Genetics Technologies Ltd | Sorting asymmetrically tagged nucleic acids by selective primer extension |
| US9524369B2 (en) | 2009-06-15 | 2016-12-20 | Complete Genomics, Inc. | Processing and analysis of complex nucleic acid sequence data |
| DK2539450T3 (da) * | 2010-02-25 | 2016-05-30 | Advanced Liquid Logic Inc | Fremgangsmåde til fremstilling af nukleinsyrebiblioteker |
| US9513253B2 (en) | 2011-07-11 | 2016-12-06 | Advanced Liquid Logic, Inc. | Droplet actuators and techniques for droplet-based enzymatic assays |
| US10191929B2 (en) | 2013-05-29 | 2019-01-29 | Noblis, Inc. | Systems and methods for SNP analysis and genome sequencing |
| US10560552B2 (en) | 2015-05-21 | 2020-02-11 | Noblis, Inc. | Compression and transmission of genomic information |
| US11222712B2 (en) | 2017-05-12 | 2022-01-11 | Noblis, Inc. | Primer design using indexed genomic information |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797355A (en) * | 1985-06-13 | 1989-01-10 | Amgen Inc. | Methods for attaching polynucleotides to supports |
| FI95398C (fi) * | 1989-06-24 | 1996-01-25 | Boehringer Ingelheim Int | Menetelmä ihmisen nuhaviruksen serotyypittämiseksi |
| CA2036946C (en) * | 1990-04-06 | 2001-10-16 | Kenneth V. Deugau | Indexing linkers |
| EP0675966B1 (de) * | 1992-02-19 | 2004-10-06 | The Public Health Research Institute Of The City Of New York, Inc. | Neue anordnungen von oligonukleotiden und ihr nutzen zum sortieren, isolieren, sequenzierung und manipulieren von nukleinsäuren |
| DE4218152A1 (de) * | 1992-06-02 | 1993-12-09 | Boehringer Mannheim Gmbh | Simultane Sequenzierung von Nukleinsäuren |
| GB9214857D0 (en) * | 1992-07-13 | 1992-08-26 | Medical Res Council | Human nucleic acid fragments and their use |
-
1992
- 1992-07-13 GB GB929214873A patent/GB9214873D0/en active Pending
-
1993
- 1993-07-13 IL IL106316A patent/IL106316A0/xx unknown
- 1993-07-13 AT AT93916049T patent/ATE159986T1/de not_active IP Right Cessation
- 1993-07-13 EP EP93916049A patent/EP0650528B1/de not_active Expired - Lifetime
- 1993-07-13 CA CA002139944A patent/CA2139944A1/en not_active Abandoned
- 1993-07-13 JP JP50313094A patent/JP3251291B2/ja not_active Expired - Fee Related
- 1993-07-13 DE DE69315074T patent/DE69315074T2/de not_active Expired - Fee Related
- 1993-07-13 WO PCT/GB1993/001452 patent/WO1994001582A1/en not_active Ceased
- 1993-07-13 AU AU45758/93A patent/AU686563B2/en not_active Ceased
-
1995
- 1995-02-16 US US08/367,266 patent/US5728524A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5728524A (en) | 1998-03-17 |
| GB9214873D0 (en) | 1992-08-26 |
| CA2139944A1 (en) | 1994-01-20 |
| DE69315074D1 (de) | 1997-12-11 |
| JPH07508883A (ja) | 1995-10-05 |
| EP0650528A1 (de) | 1995-05-03 |
| AU4575893A (en) | 1994-01-31 |
| IL106316A0 (en) | 1993-11-15 |
| WO1994001582A1 (en) | 1994-01-20 |
| JP3251291B2 (ja) | 2002-01-28 |
| AU686563B2 (en) | 1998-02-12 |
| EP0650528B1 (de) | 1997-11-05 |
| DE69315074T2 (de) | 1998-03-05 |
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