ATE160941T1 - Sulfatierte polysaccharide mit antimetastasenwirkung - Google Patents

Sulfatierte polysaccharide mit antimetastasenwirkung

Info

Publication number
ATE160941T1
ATE160941T1 AT88901519T AT88901519T ATE160941T1 AT E160941 T1 ATE160941 T1 AT E160941T1 AT 88901519 T AT88901519 T AT 88901519T AT 88901519 T AT88901519 T AT 88901519T AT E160941 T1 ATE160941 T1 AT E160941T1
Authority
AT
Austria
Prior art keywords
sulfated polysaccharides
metastasis effect
sulphate
heparin
sulphated
Prior art date
Application number
AT88901519T
Other languages
English (en)
Inventor
Christopher Richard Parish
John Mckinnon Snowden
Original Assignee
Univ Australian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Australian filed Critical Univ Australian
Application granted granted Critical
Publication of ATE160941T1 publication Critical patent/ATE160941T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT88901519T 1987-01-23 1988-01-22 Sulfatierte polysaccharide mit antimetastasenwirkung ATE160941T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPH999187 1987-01-23

Publications (1)

Publication Number Publication Date
ATE160941T1 true ATE160941T1 (de) 1997-12-15

Family

ID=3771996

Family Applications (2)

Application Number Title Priority Date Filing Date
AT94103441T ATE178212T1 (de) 1987-01-23 1988-01-22 Sulfatierte polysaccharide mit antiinflammatorischer aktivität
AT88901519T ATE160941T1 (de) 1987-01-23 1988-01-22 Sulfatierte polysaccharide mit antimetastasenwirkung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT94103441T ATE178212T1 (de) 1987-01-23 1988-01-22 Sulfatierte polysaccharide mit antiinflammatorischer aktivität

Country Status (8)

Country Link
EP (2) EP0355088B1 (de)
JP (2) JP2701904B2 (de)
AT (2) ATE178212T1 (de)
CA (1) CA1316828C (de)
DE (2) DE3856321T2 (de)
IL (1) IL85145A (de)
SG (2) SG52246A1 (de)
WO (1) WO1988005301A1 (de)

Families Citing this family (32)

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Publication number Priority date Publication date Assignee Title
IL88554A0 (en) * 1988-12-01 1989-07-31 Hadassah Med Org Compositions containing a compound binding to a heparin receptor
JPH06507635A (ja) * 1991-05-02 1994-09-01 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド 病理学的過程の予防および／または治療用組成物
US5861382A (en) * 1992-05-01 1999-01-19 Yeda Research And Development Co. Ltd. Methods for regulation of active TNF-α
US6750207B1 (en) 1992-05-01 2004-06-15 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity
IT1264709B1 (it) * 1993-07-12 1996-10-04 Italfarmaco Spa Derivati eparinici ad attivita' antimetastatica
JP3403496B2 (ja) * 1993-09-24 2003-05-06 株式会社ヤクルト本社 抗潰瘍剤およびヘリコバクター・ピロリの定着阻害剤
US5739115A (en) * 1993-10-07 1998-04-14 Glycomed Incorporated Sulfated maltooligosaccharides with heparin-like properties
EP0722326A4 (de) * 1993-10-07 1999-10-06 Glycomed Inc Hochsulfatierte maltooligossaccharide mit heparinähnlichen eigenschaften
FR2718024B1 (fr) * 1994-03-30 1996-06-21 Paris Val Marne Universite Médicament et composition pharmaceutique pour le traitement de l'inflammation.
US5783568A (en) * 1994-06-10 1998-07-21 Sugen, Inc. Methods for treating cancer and other cell proliferative diseases
DK0852491T3 (da) * 1995-09-29 2004-12-20 Biomarin Pharm Inc Anvendelse af heparinaser til at mindske inflammatoriske responser
EP0868191A1 (de) * 1995-12-18 1998-10-07 Stichting Sanquin Bloedvoorziening Potenzierung der komplement und gerinnungsinhibierenden eigenschaften von c1-inaktivator
EP0919237A4 (de) * 1996-01-26 2004-10-13 Takara Bio Inc Induktoren der apoptose
JP3505185B2 (ja) * 1996-06-12 2004-03-08 タカラバイオ株式会社 食品又は飲料
US8304390B2 (en) 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
US7151099B2 (en) 1998-07-31 2006-12-19 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Use of taurolidine and/or taurultam for treatment of abdominal cancer and/or for the prevention of metastases
US8030301B2 (en) 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US7345039B2 (en) 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
US7892530B2 (en) 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
JP4202645B2 (ja) * 1999-08-20 2008-12-24 タカラバイオ株式会社 治療剤
US6641571B2 (en) 2000-01-05 2003-11-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery
JP2005510453A (ja) 2001-04-16 2005-04-21 イヴァックス リサーチ インコーポレイテッド 高硫酸化二糖類及び炎症治療のためのそれらの使用方法
CZ307433B6 (cs) 2001-09-12 2018-08-22 Leadiant Biosciences Sa Deriváty částečně desulfátovaných glykosaminoglykanů jako inhibitory heparanázy mající antiangiogenní účinky a zabraňující antikoagulačnímu působení
US7285536B2 (en) 2001-12-05 2007-10-23 Yeda Research And Development Co., Ltd. Anti-cancer therapeutic compounds
ITMI20021294A1 (it) * 2002-06-12 2003-12-12 Inalco Spa Polisaccaridi batterici o-solfatati e loro uso
EP1709443A2 (de) 2003-12-18 2006-10-11 Procognia, Ltd. Verfahren zur analyse eines glykomoleküls
ES2399277T3 (es) 2004-05-27 2013-03-27 Baxter International Inc. Procedimiento de tratamiento de trastornos hemorrágicos utilizando polisacáridos sulfatados
JP5701498B2 (ja) * 2009-12-01 2015-04-15 公益財団法人微生物化学研究会 炎症性細胞からのヘパラナーゼの放出抑制剤、抗炎症剤、及び薬用組成物
JP5934735B2 (ja) * 2014-03-28 2016-06-15 株式会社オプトクリエーション ナノバブル・フコイダン水素水
NL2024493B1 (en) * 2019-12-16 2021-09-02 Logick Energetics B V Pharmaceutical composition for preventing or stopping metastases
EP4076439A1 (de) 2019-12-18 2022-10-26 Logick Energetics Pharmazeutische zusammensetzung zum vorbeugen oder stoppen von metastasen
WO2022265510A1 (en) * 2021-06-17 2022-12-22 Logick Energetics B.V. Pharmaceutical composition for use in the treatment of metastatic epithelial ovarian cancer, metastatic fallopian tube carcinoma or metastatic primary peritoneal carcinoma

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1730M (fr) * 1962-01-17 1963-03-18 Charles Riviere Nouvelle composition de collyre.
JPS5943929B2 (ja) * 1979-08-13 1984-10-25 サッポロビール株式会社 多糖体ｒｂｓ物質，その製法およびそれを有効成分とする抗腫瘍性剤
DE3373782D1 (en) * 1982-12-20 1987-10-29 Harvard College Inhibition of angiogenesis
AU555747B2 (en) * 1983-08-09 1986-10-09 Cilco Inc. Chondroitin sulfate and sodium hyaluronate composition
FR2553287B1 (fr) * 1983-10-18 1986-09-12 Choay Sa Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire
DE3422518A1 (de) * 1984-06-16 1985-12-19 B. Braun Melsungen Ag, 3508 Melsungen Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen
US4710493A (en) * 1984-08-14 1987-12-01 Albert Landsberger Therapeutic agent for the use in cancer treatment
FR2584606A1 (fr) * 1985-07-12 1987-01-16 Dropic Utilisation de poly- et oligosaccharides pour l'obtention de medicaments actifs dans les pathologies du tissu conjonctif
IL79255A0 (en) * 1986-06-26 1986-09-30 Hadassah Med Org Composition for metastasis prevention
IL79254A0 (en) * 1986-06-26 1986-09-30 Hadassah Med Org Compositions for preventing graft rejection
ATE129254T1 (de) * 1987-03-19 1995-11-15 Arthropharm Pty Ltd Antientzündungsmittel und zusammensetzungen.
JPH06157520A (ja) * 1992-11-13 1994-06-03 Kirin Brewery Co Ltd 新規物質ｈｑ２４

Also Published As

Publication number Publication date
CA1316828C (en) 1993-04-27
JPH02502006A (ja) 1990-07-05
HK1014153A1 (en) 1999-09-24
DE3856083T2 (de) 1998-07-02
JP2752353B2 (ja) 1998-05-18
EP0355088A4 (de) 1990-06-26
WO1988005301A1 (en) 1988-07-28
EP0355088B1 (de) 1997-12-10
DE3856321D1 (de) 1999-05-06
DE3856083D1 (de) 1998-01-22
JP2701904B2 (ja) 1998-01-21
ATE178212T1 (de) 1999-04-15
IL85145A (en) 1994-08-26
EP0355088A1 (de) 1990-02-28
EP0631784A1 (de) 1995-01-04
SG45156A1 (en) 1998-01-16
JPH09328431A (ja) 1997-12-22
EP0631784B1 (de) 1999-03-31
DE3856321T2 (de) 1999-08-26
SG52246A1 (en) 1998-09-28

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