ATE161833T1 - Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel - Google Patents

Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel

Info

Publication number
ATE161833T1
ATE161833T1 AT93923304T AT93923304T ATE161833T1 AT E161833 T1 ATE161833 T1 AT E161833T1 AT 93923304 T AT93923304 T AT 93923304T AT 93923304 T AT93923304 T AT 93923304T AT E161833 T1 ATE161833 T1 AT E161833T1
Authority
AT
Austria
Prior art keywords
tropone
group
antibacterial agent
derivatives substituted
phenyloxazolidinone
Prior art date
Application number
AT93923304T
Other languages
English (en)
Inventor
Michael Robert Barbachyn
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE161833T1 publication Critical patent/ATE161833T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT93923304T 1992-12-08 1993-10-14 Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel ATE161833T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98858992A 1992-12-08 1992-12-08
US377893A 1993-01-13 1993-01-13
US6635693A 1993-05-21 1993-05-21

Publications (1)

Publication Number Publication Date
ATE161833T1 true ATE161833T1 (de) 1998-01-15

Family

ID=27357482

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93923304T ATE161833T1 (de) 1992-12-08 1993-10-14 Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel

Country Status (20)

Country Link
US (1) US5523403A (de)
EP (1) EP0673370B1 (de)
JP (1) JP3558088B2 (de)
KR (1) KR100276382B1 (de)
AT (1) ATE161833T1 (de)
AU (1) AU670842B2 (de)
CA (1) CA2147753C (de)
CZ (1) CZ288788B6 (de)
DE (1) DE69316240T2 (de)
DK (1) DK0673370T3 (de)
ES (1) ES2111188T3 (de)
FI (1) FI952798L (de)
GR (1) GR3026228T3 (de)
HU (1) HUT74099A (de)
NO (1) NO952253L (de)
NZ (1) NZ257031A (de)
PL (1) PL175782B1 (de)
RU (1) RU2119484C1 (de)
SK (1) SK282453B6 (de)
WO (1) WO1994013649A1 (de)

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GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
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GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
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WO1999064417A2 (en) 1998-06-05 1999-12-16 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
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US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
EP1147422A1 (de) 1999-01-27 2001-10-24 Pharmacia & Upjohn Company Assays für modulatoren der "elongation factor p"-aktivität
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
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AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
EP1490059A1 (de) * 2002-03-29 2004-12-29 Pharmacia & Upjohn Company LLC Parenterale, intravenöse und orale verabreichung von oxazolidinonen zur behandlung von diabetischem fuss-syndrom
DE60304360T2 (de) * 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate
ATE344036T1 (de) * 2002-11-21 2006-11-15 Pharmacia & Upjohn Co Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinon-5- carbonsäureamid-derivate und verwandte verbindungen als antibakterielle mittel
US8050281B2 (en) * 2003-01-31 2011-11-01 Qwest Communications International Inc. Alert gateway, systems and methods
US7474742B2 (en) * 2003-01-31 2009-01-06 Qwest Communications International Inc. Environmentally-controlled network interface device and methods
US8813142B2 (en) * 2003-01-31 2014-08-19 Qwest Communications International Inc. Methods, systems and apparatus for providing video transmissions over multiple media
BRPI0407252A (pt) * 2003-02-07 2006-01-31 Warner Lambert Co Agentes antibacterianos.
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EP1656370B1 (de) * 2003-06-03 2012-08-15 Rib-X Pharmaceuticals, Inc. Heterocyclische biarylverbindungen und verfahren zu deren herstellung und anwendung
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MXPA06002188A (es) * 2003-08-25 2006-04-27 Warner Lambert Co Nuevos compuestos antimicrobianos de ariloxazolidinona.
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AR046782A1 (es) * 2003-12-17 2005-12-21 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos.
KR100854211B1 (ko) * 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
JP5534497B2 (ja) 2005-06-08 2014-07-02 メリンタ セラピューティクス，インコーポレイテッド トリアゾール類の合成方法
KR20080110877A (ko) 2006-03-31 2008-12-19 재단법인 이쯔우 연구소 헤테로환을 갖는 신규 화합물
JPWO2007116960A1 (ja) * 2006-04-06 2009-08-20 財団法人乙卯研究所 炭素環を有するオキサゾリジノン誘導体
CN101883768A (zh) * 2007-10-02 2010-11-10 财团法人乙卯研究所 具有7元杂环的噁唑烷酮衍生物
RU2659792C1 (ru) 2008-10-10 2018-07-04 Мерк Шарп Энд Домэ Корп. Оксазолидиноны и способ их очистки
MY156354A (en) 2009-02-03 2016-02-15 Merck Sharp & Dohme Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
US8580767B2 (en) * 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
WO2025134688A1 (ja) * 2023-12-22 2025-06-26 東亞合成株式会社 トロポロン誘導体

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US4340606A (en) * 1980-10-23 1982-07-20 E. I. Du Pont De Nemours And Company 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
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US4461773A (en) * 1982-09-15 1984-07-24 E. I. Dupont De Nemours And Company P-Oxooxazolidinylbenzene compounds as antibacterial agents
ES533097A0 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
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Also Published As

Publication number Publication date
CA2147753C (en) 2004-08-03
RU2119484C1 (ru) 1998-09-27
DK0673370T3 (da) 1998-09-07
CZ288788B6 (cs) 2001-09-12
EP0673370B1 (de) 1998-01-07
ES2111188T3 (es) 1998-03-01
RU95114378A (ru) 1997-06-10
CZ136695A3 (en) 1995-10-18
FI952798A0 (fi) 1995-06-07
PL309283A1 (en) 1995-10-02
AU670842B2 (en) 1996-08-01
NZ257031A (en) 1996-07-26
FI952798A7 (fi) 1995-06-07
HUT74099A (en) 1996-11-28
WO1994013649A1 (en) 1994-06-23
KR100276382B1 (ko) 2000-12-15
DE69316240T2 (de) 1998-05-20
EP0673370A1 (de) 1995-09-27
GR3026228T3 (en) 1998-05-29
HU9501670D0 (en) 1995-08-28
AU5323994A (en) 1994-07-04
CA2147753A1 (en) 1994-06-23
FI952798L (fi) 1995-06-07
JP3558088B2 (ja) 2004-08-25
NO952253L (no) 1995-08-08
US5523403A (en) 1996-06-04
DE69316240D1 (de) 1998-02-12
NO952253D0 (no) 1995-06-07
SK282453B6 (sk) 2002-02-05
PL175782B1 (pl) 1999-02-26
SK74695A3 (en) 1995-10-11
JPH08504205A (ja) 1996-05-07

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Legal Events

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REN Ceased due to non-payment of the annual fee