ATE165346T1 - Neue vitamin d-derivate - Google Patents

Neue vitamin d-derivate

Info

Publication number: ATE165346T1
Authority: AT; Austria
Prior art keywords: pct; formula; sec; hydrogen; hydroxy
Prior art date: 1993-07-12

Application number

AT94920900T

Other languages

English (en)

Inventor

Gunnar Grue-Sorensen

Original Assignee

Leo Pharm Prod Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-12

Filing date

1994-07-01

Publication date

1998-05-15

1994-07-01 Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd

1998-05-15 Application granted granted Critical

1998-05-15 Publication of ATE165346T1 publication Critical patent/ATE165346T1/de

Links

150000003710 vitamin D derivatives Chemical class 0.000 title 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
125000002837 carbocyclic group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
230000004069 differentiation Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
125000000743 hydrocarbylene group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000002519 immonomodulatory effect Effects 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Dermatology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Rheumatology (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Immunology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Dental Preparations (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT94920900T 1993-07-12 1994-07-01 Neue vitamin d-derivate ATE165346T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB939314400A GB9314400D0 (en)	1993-07-12	1993-07-12	Produktionsaktieselskab) chemical compounds

Publications (1)

Publication Number	Publication Date
ATE165346T1 true ATE165346T1 (de)	1998-05-15

Family

ID=10738689

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94920900T ATE165346T1 (de)	1993-07-12	1994-07-01	Neue vitamin d-derivate

Country Status (15)

Country	Link
US (1)	US5716945A (de)
EP (1)	EP0708755B1 (de)
JP (1)	JP3773253B2 (de)
KR (1)	KR100317869B1 (de)
CN (1)	CN1048241C (de)
AT (1)	ATE165346T1 (de)
AU (1)	AU690564B2 (de)
CA (1)	CA2162040A1 (de)
DE (1)	DE69409811T2 (de)
ES (1)	ES2117281T3 (de)
FI (1)	FI111719B (de)
GB (1)	GB9314400D0 (de)
NZ (1)	NZ268567A (de)
RU (1)	RU2130926C1 (de)
WO (1)	WO1995002577A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040167106A1 (en) *	1993-06-04	2004-08-26	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of a Vitamin D compound
US6407082B1 (en) *	1996-09-13	2002-06-18	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a vitamin D compound
DE19619036A1 (de)	1996-04-30	1997-11-13	Schering Ag	Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
WO1998001135A1 (fr) *	1996-07-03	1998-01-15	Sanwa Kagaku Kenkyusho Co., Ltd.	Agents d'elimination du phosphore, inhibiteurs augmentant le taux serique de parathormone et inhibiteurs de l'osteodystrophie
JP2002513416A (ja)	1997-05-22	2002-05-08	セファロン・インコーポレイテッド	ビタミンｄアナログおよびそれらのニューロン効果
WO1999003828A1 (en) *	1997-07-17	1999-01-28	F.Hoffmann-La Roche Ag	Dihomo-seco-cholestanes with two unsaturated bones in the side chain
ES2388425T5 (es) *	1999-04-23	2020-02-12	Leo Pharma As	Composición farmacéutica no acuosa para uso dérmico para tratar la psoriasis que comprende una vitamina D, un corticoesteroide y un componente disolvente
DE60019947T2 (de)	1999-09-29	2006-02-02	Colotech A/S	Prävention von kolorektalem Krebs
US6703380B2 (en)	1999-09-29	2004-03-09	Colotech A/S	Prevention of cancer
US6989377B2 (en)	1999-12-21	2006-01-24	Wisconsin Alumni Research Foundation	Treating vitamin D responsive diseases
US6358939B1 (en)	1999-12-21	2002-03-19	Northern Lights Pharmaceuticals, Llc	Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US20020183277A1 (en) *	2001-05-15	2002-12-05	Lise Binderup	Combination of vitamin D analogue and pyrimidine nucleoside analogue
AR041696A1 (es)	2002-10-23	2005-05-26	Leo Pharm Prod Ltd	Compuestos analogos de vitamina d, composiciones que comprenden dichos compuestos analogos y su uso
MXPA05003499A (es) *	2002-10-23	2005-06-17	Leo Pharma As	Analogos de vitamina d, composiciones que los comprenden y su uso.
EP1458678A1 (de) *	2002-11-18	2004-09-22	Teva Pharmaceutical Industries Limited	Kristallisationsverfahren zur reinigung von calcipotriene
ES2234423B1 (es) *	2003-12-05	2006-03-01	Laboratorios Viñas, S.A.	Procedimiento para la obtencion de derivados de vitamina d a partir de compuestos monohalogenovinilicos.
EP1812011A1 (de)	2004-11-12	2007-08-01	Bioxell S.p.a.	Kombinierte verwendung von vitamin-d-derivaten und antiproliferativen mitteln zur behandlung von blasenkrebs
AU2010208323B2 (en)	2009-01-27	2016-03-10	Berg Llc	Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (de)	2009-08-14	2019-05-22	Berg LLC	Vitamin d3 und analoge davon zur behandlung von alopezie
SG10201709894RA (en)	2013-05-29	2018-01-30	Berg Llc	Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN103508999B (zh) *	2013-10-12	2015-05-13	浙江海正药业股份有限公司	马沙骨化醇的合成中间体及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4804502A (en) *	1988-01-20	1989-02-14	Hoffmann-La Roche Inc.	Vitamin D compounds
US5145846A (en) *	1988-01-20	1992-09-08	Hoffmann-La Roche Inc.	Vitamin D3 analogs
EP0412110B1 (de) *	1988-04-21	1993-07-07	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab)	Vitamin d analoge
US5378695A (en) *	1989-02-23	1995-01-03	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab)	Vitamin D analogues
GB8915770D0 (en) *	1989-07-10	1989-08-31	Leo Pharm Prod Ltd	Chemical compounds
GB9007236D0 (en) *	1990-03-30	1990-05-30	Leo Pharm Prod Ltd	Chemical compounds
GB9223061D0 (en) *	1992-11-04	1992-12-16	Leo Pharm Prod Ltd	Chemical compounds
GB9226877D0 (en) *	1992-12-23	1993-02-17	Leo Pharm Prod Ltd	Chemical compounds
US5449668A (en) *	1993-06-04	1995-09-12	Duphar International Research B.V.	Vitamin D compounds and method of preparing these compounds

1993
- 1993-07-12 GB GB939314400A patent/GB9314400D0/en active Pending
1994
- 1994-07-01 DE DE69409811T patent/DE69409811T2/de not_active Expired - Fee Related
- 1994-07-01 WO PCT/DK1994/000271 patent/WO1995002577A1/en not_active Ceased
- 1994-07-01 JP JP50429595A patent/JP3773253B2/ja not_active Expired - Fee Related
- 1994-07-01 AU AU71829/94A patent/AU690564B2/en not_active Ceased
- 1994-07-01 NZ NZ268567A patent/NZ268567A/en unknown
- 1994-07-01 CN CN94192588A patent/CN1048241C/zh not_active Expired - Fee Related
- 1994-07-01 AT AT94920900T patent/ATE165346T1/de not_active IP Right Cessation
- 1994-07-01 EP EP94920900A patent/EP0708755B1/de not_active Expired - Lifetime
- 1994-07-01 CA CA002162040A patent/CA2162040A1/en not_active Abandoned
- 1994-07-01 KR KR1019950705068A patent/KR100317869B1/ko not_active Expired - Fee Related
- 1994-07-01 RU RU96102611A patent/RU2130926C1/ru not_active IP Right Cessation
- 1994-07-01 ES ES94920900T patent/ES2117281T3/es not_active Expired - Lifetime
- 1994-07-01 US US08/545,762 patent/US5716945A/en not_active Expired - Fee Related
1995
- 1995-12-19 FI FI956108A patent/FI111719B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
RU2130926C1 (ru)	1999-05-27
WO1995002577A1 (en)	1995-01-26
JPH08512327A (ja)	1996-12-24
ES2117281T3 (es)	1998-08-01
GB9314400D0 (en)	1993-08-25
KR100317869B1 (ko)	2002-09-27
FI956108A7 (fi)	1995-12-19
EP0708755B1 (de)	1998-04-22
DE69409811T2 (de)	1999-01-07
CN1125941A (zh)	1996-07-03
DE69409811D1 (de)	1998-05-28
NZ268567A (en)	1997-11-24
FI956108A0 (fi)	1995-12-19
AU690564B2 (en)	1998-04-30
CA2162040A1 (en)	1995-01-26
KR960702436A (ko)	1996-04-27
AU7182994A (en)	1995-02-13
JP3773253B2 (ja)	2006-05-10
EP0708755A1 (de)	1996-05-01
US5716945A (en)	1998-02-10
CN1048241C (zh)	2000-01-12
FI111719B (fi)	2003-09-15

Legal Events

Date	Code	Title	Description
1999-01-15	UEP	Publication of translation of european patent specification
2008-04-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69409811D1 (de)	1998-05-28	Neue vitamin d-derivate
ATE150013T1 (de)	1997-03-15	Vitamin d derivate
FI943099A0 (fi)	1994-06-28	Uudet D-vitamiinianalogit
ATE114302T1 (de)	1994-12-15	Vitamin-d-derivate.
DE69714590D1 (de)	2002-09-12	Vitamin d analoge verbindungen
ATE60763T1 (de)	1991-02-15	Pyrrolidinylamidesterderivate mit antiprolylendopeptidaseaktivitaet, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen.
DE69608701D1 (de)	2000-07-06	Vitamin d analoge
DE69712086D1 (de)	2002-05-23	Vitamin d derivate
ATE154596T1 (de)	1997-07-15	Neue vitamin d derivate