ATE114302T1 - Vitamin-d-derivate. - Google Patents

Vitamin-d-derivate.

Info

Publication number
ATE114302T1
ATE114302T1 AT91907179T AT91907179T ATE114302T1 AT E114302 T1 ATE114302 T1 AT E114302T1 AT 91907179 T AT91907179 T AT 91907179T AT 91907179 T AT91907179 T AT 91907179T AT E114302 T1 ATE114302 T1 AT E114302T1
Authority
AT
Austria
Prior art keywords
pct
hydrogen
formula
hydrocarbyl
sec
Prior art date
Application number
AT91907179T
Other languages
English (en)
Inventor
Martin John Calverley
Gunnar Grue-Soerensen
Ernst Torndal Binderup
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Application granted granted Critical
Publication of ATE114302T1 publication Critical patent/ATE114302T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT91907179T 1990-03-30 1991-03-22 Vitamin-d-derivate. ATE114302T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909007236A GB9007236D0 (en) 1990-03-30 1990-03-30 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE114302T1 true ATE114302T1 (de) 1994-12-15

Family

ID=10673606

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91907179T ATE114302T1 (de) 1990-03-30 1991-03-22 Vitamin-d-derivate.

Country Status (15)

Country Link
US (1) US5374629A (de)
EP (1) EP0522013B1 (de)
JP (1) JP3246913B2 (de)
KR (1) KR100209179B1 (de)
AT (1) ATE114302T1 (de)
AU (1) AU630804B2 (de)
CA (1) CA2073983C (de)
DE (1) DE69105267T2 (de)
DK (1) DK0522013T3 (de)
ES (1) ES2066434T3 (de)
GB (1) GB9007236D0 (de)
GR (1) GR3015127T3 (de)
IE (1) IE65283B1 (de)
NZ (1) NZ237607A (de)
WO (1) WO1991015475A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4101953A1 (de) * 1991-01-19 1992-07-23 Schering Ag 23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
GB9223061D0 (en) * 1992-11-04 1992-12-16 Leo Pharm Prod Ltd Chemical compounds
US20040167106A1 (en) * 1993-06-04 2004-08-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of a Vitamin D compound
US6407082B1 (en) 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
GB9314400D0 (en) * 1993-07-12 1993-08-25 Leo Pharm Prod Ltd Produktionsaktieselskab) chemical compounds
ATE195513T1 (de) * 1994-04-11 2000-09-15 Chugai Pharmaceutical Co Ltd 22-thiavitamin-d3-derivate
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US6242434B1 (en) 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
CA2175881A1 (en) * 1995-05-09 1996-11-10 Andrzej Kutner Vitamin d compounds and methods of preparing these compounds
DE19519273A1 (de) * 1995-05-22 1996-11-28 Schering Ag Topisch applizierbare Mittel zur Behandlung und Prophylaxe der Alopezie
AU7364896A (en) * 1995-10-10 1997-04-30 Marilyn Strube Treatment of pruritus with vitamin d and analogs thereof
US5738745A (en) * 1995-11-27 1998-04-14 Kimberly-Clark Worldwide, Inc. Method of improving the photostability of polypropylene compositions
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6034074A (en) * 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
DK0947504T3 (da) * 1996-12-20 2003-11-24 Chugai Pharmaceutical Co Ltd 16-en-vitamin D-derivater
MA26481A1 (fr) * 1997-04-21 2004-12-20 Hoffmann La Roche Derives d'arylsecocholadiene
US6207656B1 (en) 1997-05-22 2001-03-27 Cephalon, Inc. Vitamin D analogues and their neuronal effects
JP2002510304A (ja) * 1997-06-06 2002-04-02 ウイスコンシン アラムナイ リサーチ フオンデーシヨン 移植体拒絶反応を防ぐためのビタミンｄ化合物の使用
ES2368824T3 (es) 1998-03-27 2011-11-22 Oregon Health & Science University Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos.
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
EP1745787B1 (de) * 1999-04-01 2016-11-09 Johns Hopkins University NICHT-CALCEMISCHE, TRANSKRIPTIONELL-AKTIVE, SCHWEFELHALTIGE ANALOGA VON 1-alpha, 25-DIHYDROXYVITAMIN D3 MIT ANTIPROLIFERATIVER WIRKUNG
HUP0200812A3 (en) * 1999-04-23 2003-07-28 Leo Pharm Prod Ltd Vitamin d analogues and their pharmaceutical use
WO2006120681A2 (en) 2005-05-10 2006-11-16 Dermipsor Ltd. Compositions and methods for skin care
AU776755B2 (en) * 2000-01-31 2004-09-23 Leo Pharma A/S Use of vitamin D-derivatives in the treatment of osteoporosis and related bone disorders, as well as novel vitamin D3-derivatives
AU2001228330A1 (en) * 2000-01-31 2001-08-14 Leo Pharma A/S Vitamin d-derivatives and their use in treating osteoporosis and related bone disorders
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
WO2003018545A1 (en) * 2001-08-22 2003-03-06 Johns Hopkins University 24-sulfur-substituted analogs of 1α,25-dihydroxy vitamin d¿3?
US7101865B2 (en) 2002-06-13 2006-09-05 Cytochroma Inc. 24-sulfoximine vitamin D3 compounds
US8106035B2 (en) 2002-12-18 2012-01-31 Cytochroma Inc. 25-SO2-substituted analogs of 1μ,25-dihydroxyvitamin D3
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
CA2586679A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
US9173835B2 (en) 2005-05-10 2015-11-03 Dermipsor Ltd. Compositions and methods for treating hyperproliferative epidermal diseases
EP2144872A2 (de) * 2007-04-18 2010-01-20 Johns Hopkins University Gering kalzämische und hoch antiproliferative calcitriol-analoga
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
CA2981549A1 (en) 2009-01-27 2010-08-05 Berg Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
CN106265695B (zh) 2009-08-14 2021-05-07 博格有限责任公司 用于治疗脱发的维生素d3及其类似物
CN112156097A (zh) 2013-05-29 2021-01-01 博格有限责任公司 使用维生素d预防或减轻化疗诱发的脱发
US20190183908A1 (en) 2016-05-13 2019-06-20 Case Western Reserve University Autophagy activators for treating or preventing skin injury

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078704B1 (de) * 1981-11-02 1987-04-29 Research Institute For Medicine And Chemistry Inc. Zwischenprodukte in der Synthese von Vitamin D Derivaten
IL77668A (en) * 1986-01-21 1989-03-31 Teva Pharma Production of cholecalciferol derivatives and novel intermediates used therefor
EP0296800B1 (de) * 1987-06-23 1991-10-16 Yamanouchi Pharmaceutical Co. Ltd. Vitamin D3-Derivate
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
WO1990000560A1 (en) * 1988-07-05 1990-01-25 Kuraray Co., Ltd. Steroid compounds
JPH0667898B2 (ja) * 1989-02-15 1994-08-31 大同ほくさん株式会社 ２２，２３―セコビタミンｄ若しくはその活性型またはそれらの誘導体の製造方法

Also Published As

Publication number Publication date
KR920703527A (ko) 1992-12-18
NZ237607A (en) 1993-05-26
ES2066434T3 (es) 1995-03-01
CA2073983A1 (en) 1991-10-01
DE69105267T2 (de) 1995-04-27
IE65283B1 (en) 1995-10-18
KR100209179B1 (ko) 1999-07-15
GB9007236D0 (en) 1990-05-30
IE910970A1 (en) 1991-10-09
EP0522013A1 (de) 1993-01-13
JP3246913B2 (ja) 2002-01-15
WO1991015475A1 (en) 1991-10-17
EP0522013B1 (de) 1994-11-23
GR3015127T3 (en) 1995-05-31
DK0522013T3 (da) 1995-01-30
AU7589291A (en) 1991-10-30
AU630804B2 (en) 1992-11-05
DE69105267D1 (de) 1995-01-05
JPH05505613A (ja) 1993-08-19
US5374629A (en) 1994-12-20
CA2073983C (en) 2002-08-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee