ATE168696T1 - 5'(oh) und/oder 3'(oh) zur einführung von einem oder mehreren nichtradioaktivmarkierten markern chemisch modifizierte nukleinsäuresonden, und verfahren zu ihrer herstellung - Google Patents

5'(oh) und/oder 3'(oh) zur einführung von einem oder mehreren nichtradioaktivmarkierten markern chemisch modifizierte nukleinsäuresonden, und verfahren zu ihrer herstellung

Info

Publication number
ATE168696T1
ATE168696T1 AT94906099T AT94906099T ATE168696T1 AT E168696 T1 ATE168696 T1 AT E168696T1 AT 94906099 T AT94906099 T AT 94906099T AT 94906099 T AT94906099 T AT 94906099T AT E168696 T1 ATE168696 T1 AT E168696T1
Authority
AT
Austria
Prior art keywords
groups
pct
alkyl groups
nucleic acid
sequence
Prior art date
Application number
AT94906099T
Other languages
English (en)
Inventor
Vos Marie-Joelle De
Alex Bollen
Original Assignee
Wallone Region
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallone Region filed Critical Wallone Region
Application granted granted Critical
Publication of ATE168696T1 publication Critical patent/ATE168696T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT94906099T 1993-02-19 1994-02-18 5'(oh) und/oder 3'(oh) zur einführung von einem oder mehreren nichtradioaktivmarkierten markern chemisch modifizierte nukleinsäuresonden, und verfahren zu ihrer herstellung ATE168696T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE9300160A BE1007918A3 (fr) 1993-02-19 1993-02-19 Sondes d'acides nucleiques chimiquement modifiees en 5'(oh) et/ou en 3'(oh) en vue de l'introduction en ces positions d'un ou plusieurs elements de marquage non radioactif et procede de preparation.

Publications (1)

Publication Number Publication Date
ATE168696T1 true ATE168696T1 (de) 1998-08-15

Family

ID=3886855

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94906099T ATE168696T1 (de) 1993-02-19 1994-02-18 5'(oh) und/oder 3'(oh) zur einführung von einem oder mehreren nichtradioaktivmarkierten markern chemisch modifizierte nukleinsäuresonden, und verfahren zu ihrer herstellung

Country Status (11)

Country Link
US (1) US5969128A (de)
EP (1) EP0684954B1 (de)
JP (1) JPH08511678A (de)
AT (1) ATE168696T1 (de)
BE (1) BE1007918A3 (de)
CA (1) CA2155757A1 (de)
DE (1) DE69411891T2 (de)
ES (1) ES2122233T3 (de)
FI (1) FI953897A7 (de)
NO (1) NO953251D0 (de)
WO (1) WO1994019364A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW375529B (en) 1997-05-14 1999-12-01 Sega Corp Data transmission method and game system using the same
DE19736591A1 (de) * 1997-08-22 1999-02-25 Peter Prof Dr Hegemann Verfahren zum Herstellen von Nukleinsäurepolymeren
US7230095B2 (en) 2001-04-30 2007-06-12 Avecia Biotechnology Inc. Immobilization of oligonucleotides onto solid supports
DE10247790A1 (de) * 2002-10-14 2004-04-22 Chemogenix Gmbh Verfahren zur Herstellung von Oligonukleotidkonjugaten
WO2004063208A1 (en) * 2003-01-09 2004-07-29 Postech Foundation New phosphoramidite compounds
US20100120031A1 (en) * 2006-09-22 2010-05-13 The United States Of America, As Represented By The Secretary, Dept. Of Synthesis of trans-tert-butyl-2-aminocyclopentylcarbamate
WO2018013999A1 (en) 2016-07-15 2018-01-18 Am Chemicals Llc Non-nucleosidic solid supports and phosphoramidite building blocks for oligonucleotide synthesis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743535A (en) * 1984-11-07 1988-05-10 Miles Inc. Hybridization assay employing labeled probe and anti-hybrid
US4910300A (en) * 1985-12-11 1990-03-20 Chiron Corporation Method for making nucleic acid probes
CA1339351C (en) * 1987-10-15 1997-08-26 Michael S. Urdea Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
SE8802574D0 (sv) * 1988-07-08 1988-07-08 Wallac Oy Oligonucleotide hybridization probes and means for the synthesis of the most preferred probes
GB9009980D0 (en) * 1990-05-03 1990-06-27 Amersham Int Plc Phosphoramidite derivatives,their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides
JP3256539B2 (ja) * 1990-08-28 2002-02-12 エポック・ファーマシューティカルズ・インコーポレイテッド 連結分子を介する３’―尾分子付オリゴヌクレオチドの固体支持体合成
WO1992005186A1 (en) * 1990-09-20 1992-04-02 Gilead Sciences Modified internucleoside linkages

Also Published As

Publication number Publication date
WO1994019364A3 (fr) 1994-10-13
DE69411891D1 (de) 1998-08-27
FI953897A7 (fi) 1995-10-02
CA2155757A1 (fr) 1994-09-01
US5969128A (en) 1999-10-19
JPH08511678A (ja) 1996-12-10
EP0684954A1 (de) 1995-12-06
NO953251L (no) 1995-08-18
BE1007918A3 (fr) 1995-11-21
NO953251D0 (no) 1995-08-18
DE69411891T2 (de) 1999-03-11
FI953897A0 (fi) 1995-08-18
WO1994019364A2 (fr) 1994-09-01
EP0684954B1 (de) 1998-07-22
ES2122233T3 (es) 1998-12-16

Similar Documents

Publication Publication Date Title
DE69733958D1 (de) Verfahren zur positionierung von klonen mittels molekularen kaemmens
DE60016947D1 (de) Template abhängige ligierung mit pna-dna chimerischen sonden
DE69421514D1 (de) Reagens und verfahren für den nachweis einer nukleotidischen sequenz mit signalamplifizierung
DE69312498D1 (de) Verfahren zur markierung einer flüssigkeit
DE69603723D1 (de) Verfahren zum nachweis von nukleinsäuren
FI106871B (fi) Menetelmä nukleiinihapon tietyssä asemassa olevan nukleotidiemäksen tunnistamiseksi
SE9400522D0 (sv) Method and reagent for detecting specific nucleotide sequences
DE69737450D1 (de) Sequenzierung durch ligation kodierter adapter
WO2002090581A3 (en) A molecular tag code for monitoring a product and process using same
DE69123621D1 (de) Signalamplifikation einer DNS-Sonde
ATE282717T1 (de) Neuartiges verfahren zur identifizierung von klonen mit einer gewünschten biologischen eigenschaft, ausgehend von einer expressionsgenbank
ATE159986T1 (de) Verfahren zum kategorisieren von nukleotidsequenz-populationen
DE69937447D1 (de) Verfahren zur erkennung von nukleinsäuren
WO2017188669A3 (ko) 절단된 상보적인 태그 절편을 이용한 표적 핵산 서열 검출 방법 및 그 조성물
Atmadja et al. The tertiary folding of Escherichia coli 16S RNA, as studied by in situ intra-RNA cross-linking of 30S ribosomal subunits with bis-(2-chloroethyI)-methylamine
DE69411891D1 (de) 5'(oh) und/oder 3'(oh) zur einführung von einem oder mehreren nichtradioaktivmarkierten markern chemisch modifizierte nukleinsäuresonden, und verfahren zu ihrer herstellung
ATE298804T1 (de) Verfahren zur nachweis von nukleinsäuren
CA2349810C (en) Isometric primer extension method and kit for detection and quantification of specific nucleic acid
KR101903334B1 (ko) 마이크로새틀라이트 마커 조성물을 활용한 개의 개체식별 및 친자확인 방법
DE3485811D1 (de) Molekulare genetische sonde und verfahren zu ihrer herstellung, testmethode und satz in denen diese molekulare genetische sonde gebraucht wird.
DE69929365D1 (de) Systeme und verfahren zum sequenzieren durch hybridation
ATE211507T1 (de) Nachweis von nukleotidsequenzen durch signalamplifizierung
DE69630517D1 (de) Sonde zur anwendung in der analyse von nukleinsaüren und verfahren der detektion basierend auf excimer-fluoreszenz
CN119824136A (zh) 一种用于斯特提棉、灰白棉棉种鉴定的特异引物组及其应用
DK1366187T3 (da) Oligonukleotider til mærkning af oligonukleotidprober og proteiner

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee