ATE301724T1 - Verfahren zur positionierung von klonen mittels molekularen kaemmens - Google Patents

Verfahren zur positionierung von klonen mittels molekularen kaemmens

Info

Publication number
ATE301724T1
ATE301724T1 AT97912288T AT97912288T ATE301724T1 AT E301724 T1 ATE301724 T1 AT E301724T1 AT 97912288 T AT97912288 T AT 97912288T AT 97912288 T AT97912288 T AT 97912288T AT E301724 T1 ATE301724 T1 AT E301724T1
Authority
AT
Austria
Prior art keywords
dna
probes
several
reacting
combing
Prior art date
Application number
AT97912288T
Other languages
English (en)
Inventor
Aaron Bensimon
David Bensimon
Xavier Michalet
Original Assignee
Pasteur Institut
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9613276A external-priority patent/FR2755147B1/fr
Application filed by Pasteur Institut, Centre Nat Rech Scient filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE301724T1 publication Critical patent/ATE301724T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10—Ploidy or copy number detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Lasers (AREA)
  • Control Of Stepping Motors (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Position Fixing By Use Of Radio Waves (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97912288T 1996-10-30 1997-10-30 Verfahren zur positionierung von klonen mittels molekularen kaemmens ATE301724T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9613276A FR2755147B1 (fr) 1996-10-30 1996-10-30 Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic
FR9702999A FR2755149B1 (fr) 1996-10-30 1997-03-13 Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic
PCT/FR1997/001949 WO1998018959A1 (fr) 1996-10-30 1997-10-30 Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic

Publications (1)

Publication Number Publication Date
ATE301724T1 true ATE301724T1 (de) 2005-08-15

Family

ID=26233071

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97912288T ATE301724T1 (de) 1996-10-30 1997-10-30 Verfahren zur positionierung von klonen mittels molekularen kaemmens

Country Status (10)

Country Link
US (4) US6344319B1 (de)
EP (1) EP0935674B1 (de)
JP (3) JP4226078B2 (de)
AT (1) ATE301724T1 (de)
AU (1) AU4953397A (de)
DE (1) DE69733958T2 (de)
DK (1) DK0935674T3 (de)
ES (1) ES2247623T3 (de)
FR (1) FR2755149B1 (de)
WO (1) WO1998018959A1 (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2755149B1 (fr) * 1996-10-30 1999-01-15 Pasteur Institut Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic
US6573369B2 (en) 1999-05-21 2003-06-03 Bioforce Nanosciences, Inc. Method and apparatus for solid state molecular analysis
US20020042081A1 (en) 2000-10-10 2002-04-11 Eric Henderson Evaluating binding affinities by force stratification and force panning
US6696022B1 (en) * 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
US6897015B2 (en) 2000-03-07 2005-05-24 Bioforce Nanosciences, Inc. Device and method of use for detection and characterization of pathogens and biological materials
CA2403874A1 (en) * 2000-03-28 2001-12-06 Dana-Farber Cancer Institute, Inc. Molecular database for antibody characterization
EP1348113B1 (de) 2000-08-15 2008-07-30 Bioforce Nanosciences, Inc. Vorrichtung zur bildung von nanomolekularen netzwerken
AU2002318336A1 (en) * 2001-06-08 2002-12-23 U.S. Genomics, Inc. Methods and products for analyzing nucleic acids based on methylation status
US20030054386A1 (en) * 2001-06-22 2003-03-20 Stylianos Antonarakis Method for detecting diseases caused by chromosomal imbalances
AU2002336613A1 (en) * 2001-09-18 2003-04-01 U.S. Genomics, Inc. Differential tagging of polymers for high resolution linear analysis
US7042488B2 (en) 2001-09-27 2006-05-09 Fujinon Corporation Electronic endoscope for highlighting blood vessel
AU2003238796A1 (en) * 2002-05-28 2003-12-12 U.S. Genomics, Inc. Methods and apparati using single polymer analysis
US7282330B2 (en) * 2002-05-28 2007-10-16 U.S. Genomics, Inc. Methods and apparati using single polymer analysis
US6952651B2 (en) * 2002-06-17 2005-10-04 Intel Corporation Methods and apparatus for nucleic acid sequencing by signal stretching and data integration
NL1021160C2 (nl) * 2002-07-26 2004-01-27 Multigen Internat B V Werkwijze voor het bepalen van het kopieaantal van een nucleotidevolgorde.
WO2004038037A2 (en) * 2002-09-20 2004-05-06 Intel Corporation Controlled alignment of nano-barcodes encoding specific information for scanning probe microscopy (spm) reading
US7361821B2 (en) * 2002-09-20 2008-04-22 Intel Corporation Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading
US7606403B2 (en) * 2002-10-17 2009-10-20 Intel Corporation Model-based fusion of scanning probe microscopic images for detection and identification of molecular structures
US7704687B2 (en) * 2002-11-15 2010-04-27 The Johns Hopkins University Digital karyotyping
CN1745179A (zh) 2003-01-02 2006-03-08 拜澳富斯毫微科学有限公司 在小样品体积中分子分析的方法和装置
US20050123944A1 (en) * 2003-08-01 2005-06-09 U.S. Genomics, Inc. Methods and compositions related to the use of sequence-specific endonucleases for analyzing nucleic acids under non-cleaving conditions
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
US20050147976A1 (en) * 2003-12-29 2005-07-07 Xing Su Methods for determining nucleotide sequence information
US20050151126A1 (en) * 2003-12-31 2005-07-14 Intel Corporation Methods of producing carbon nanotubes using peptide or nucleic acid micropatterning
EP1725587A2 (de) * 2004-03-19 2006-11-29 U.S. Genomics, Inc. Zusammensetzungen und verfahren zum nachweis von einzelnen molekülen
US7736818B2 (en) 2004-12-27 2010-06-15 Inphase Technologies, Inc. Holographic recording medium and method of making it
US8551760B2 (en) * 2005-09-05 2013-10-08 Shimadzu Corporation Substrate for immobilizing biopolymer and method of immobilizing biopolymer by using the same
JP5700911B2 (ja) * 2005-12-23 2015-04-15 ナノストリング テクノロジーズ，インコーポレーテッド 配向され、固定化された巨大分子を含む組成物とその製造法
ATE525482T1 (de) 2005-12-23 2011-10-15 Nanostring Technologies Inc Nanoreporter und verfahren zu deren herstellung und verwendung
US20100285993A1 (en) * 2006-02-14 2010-11-11 Gregory Prelich Systematic Genomic Library and Uses Thereof
CA2653095C (en) * 2006-05-22 2013-07-16 Nanostring Technologies, Inc. Systems and methods for analyzing nanoreporters
EP2049262A2 (de) 2006-07-19 2009-04-22 Bionanomatrix, Inc. Nanodüsen-geräteanordnungen: ihre herstellung und verwendung zur makromolekularen analyse
JP5211790B2 (ja) * 2007-03-26 2013-06-12 住友化学株式会社 Ｄｎａメチル化測定方法
CA2964611C (en) * 2007-03-28 2021-06-01 Bionano Genomics, Inc. Methods of macromolecular analysis using nanochannel arrays
AU2008237018B2 (en) * 2007-04-10 2014-04-03 Bruker Spatial Biology, Inc. Methods and computer systems for identifying target-specific sequences for use in nanoreporters
JP5260981B2 (ja) * 2008-02-22 2013-08-14 株式会社日立ハイテクノロジーズ 真空処理装置
CA3062190C (en) 2008-06-30 2023-03-28 Bionano Genomics, Inc. Methods and devices for single-molecule whole genome analysis
JP2010068800A (ja) * 2008-08-19 2010-04-02 Sumitomo Chemical Co Ltd Ｄｎａを定量又は検出する方法
EP2175037B1 (de) 2008-09-26 2017-10-11 Genomic Vision Verfahren zur Analyse von D4Z4-Tandemwiederholungsarrays von Nukleinsäure und Kit dafür
AU2009316628B2 (en) 2008-11-18 2016-06-16 Bionano Genomics, Inc. Polynucleotide mapping and sequencing
US8709717B2 (en) 2009-04-03 2014-04-29 Illumina, Inc. Generation of uniform fragments of nucleic acids using patterned substrates
CN105734170A (zh) * 2010-04-23 2016-07-06 基因组影像公司 通过由分子梳检测基因组和感染性病毒dna的病毒感染的诊断
EP3078754A1 (de) 2010-09-24 2016-10-12 Genomic Vision Verfahren für den nachweis, die quantifizierung und kartierung von schäden und/oder reparaturen von dna-strängen
EP2714931A1 (de) 2011-06-03 2014-04-09 Genomic Vision Beurteilung des krebsrisikos auf der basis von rnu2-cnv und wechselwirkung zwischen rnu2 und brca1
WO2013064896A1 (en) * 2011-10-31 2013-05-10 Genomic Vision Method for identifying or detecting genomic rearrangements in a biological sample
US9028776B2 (en) 2012-04-18 2015-05-12 Toxic Report Llc Device for stretching a polymer in a fluid sample
HK1223659A1 (zh) 2013-06-14 2017-08-04 Nanostring Technologies, Inc. 基於可多重标签的报告系统
CN110168102A (zh) 2016-11-15 2019-08-23 基因组影像公司 利用分子梳理监测经修饰的核酸酶诱导的基因编辑事件的方法
WO2018100431A1 (en) 2016-11-29 2018-06-07 Genomic Vision Method for designing a set of polynucleotide sequences for analysis of specific events in a genetic region of interest
EP3717645A4 (de) * 2017-11-29 2021-09-01 XGenomes Corp. Sequenzierung von nukleinsäuren durch austritt
CA3140900A1 (en) * 2019-05-29 2020-12-03 Xgenomes Corp. Sequencing by emergence
WO2021222512A1 (en) 2020-04-30 2021-11-04 Dimensiongen Devices and methods for macromolecular manipulation
CN116171331A (zh) 2020-06-01 2023-05-26 德迈逊科技有限公司 用于基因组分析的装置和方法
WO2022035729A1 (en) 2020-08-10 2022-02-17 Dimensiongen Devices and methods for multi-dimensional genome analysis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079169A (en) * 1990-05-22 1992-01-07 The Regents Of The Stanford Leland Junior University Method for optically manipulating polymer filaments
JP3123249B2 (ja) * 1991-09-10 2001-01-09 株式会社日立製作所 Ｄｎａ分子の長さ計測方法および計測装置
DE69330750T2 (de) * 1992-03-04 2002-07-04 The Regents Of The University Of California, Oakland Vergleichende genomhybridisierung
WO1994016104A1 (en) * 1993-01-08 1994-07-21 Ctrc Research Foundation Color imaging system for use in molecular biology
US5472842A (en) * 1993-10-06 1995-12-05 The Regents Of The University Of California Detection of amplified or deleted chromosomal regions
WO1995014106A2 (en) 1993-11-17 1995-05-26 Id Biomedical Corporation Cycling probe cleavage detection of nucleic acid sequences
FR2716263B1 (fr) 1994-02-11 1997-01-17 Pasteur Institut Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon.
US5830645A (en) * 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US5851769A (en) * 1995-09-27 1998-12-22 The Regents Of The University Of California Quantitative DNA fiber mapping
CA2235395A1 (en) * 1995-11-13 1997-05-22 Institut Pasteur Ultrahigh resolution comparative nucleic acid hybridization to combed dna fibers
FR2755149B1 (fr) * 1996-10-30 1999-01-15 Pasteur Institut Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic

Also Published As

Publication number Publication date
DE69733958D1 (de) 2005-09-15
JP2008061651A (ja) 2008-03-21
FR2755149B1 (fr) 1999-01-15
DE69733958T2 (de) 2006-05-18
JP2008067716A (ja) 2008-03-27
JP4223538B2 (ja) 2009-02-12
DK0935674T3 (da) 2005-12-05
EP0935674B1 (de) 2005-08-10
FR2755149A1 (fr) 1998-04-30
US20090123926A1 (en) 2009-05-14
US6344319B1 (en) 2002-02-05
JP2001507929A (ja) 2001-06-19
US7732143B2 (en) 2010-06-08
US20020048767A1 (en) 2002-04-25
ES2247623T3 (es) 2006-03-01
US20040033510A1 (en) 2004-02-19
EP0935674A1 (de) 1999-08-18
WO1998018959A1 (fr) 1998-05-07
JP4226078B2 (ja) 2009-02-18
US7368234B2 (en) 2008-05-06
JP4223539B2 (ja) 2009-02-12
AU4953397A (en) 1998-05-22

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