ATE301724T1 - Verfahren zur positionierung von klonen mittels molekularen kaemmens - Google Patents
Verfahren zur positionierung von klonen mittels molekularen kaemmensInfo
- Publication number
- ATE301724T1 ATE301724T1 AT97912288T AT97912288T ATE301724T1 AT E301724 T1 ATE301724 T1 AT E301724T1 AT 97912288 T AT97912288 T AT 97912288T AT 97912288 T AT97912288 T AT 97912288T AT E301724 T1 ATE301724 T1 AT E301724T1
- Authority
- AT
- Austria
- Prior art keywords
- dna
- probes
- several
- reacting
- combing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000523 sample Substances 0.000 abstract 5
- 108020004414 DNA Proteins 0.000 abstract 4
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 208000026350 Inborn Genetic disease Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 208000016361 genetic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/10—Ploidy or copy number detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Lasers (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Position Fixing By Use Of Radio Waves (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Control Of Stepping Motors (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9613276A FR2755147B1 (fr) | 1996-10-30 | 1996-10-30 | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
| FR9702999A FR2755149B1 (fr) | 1996-10-30 | 1997-03-13 | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
| PCT/FR1997/001949 WO1998018959A1 (fr) | 1996-10-30 | 1997-10-30 | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE301724T1 true ATE301724T1 (de) | 2005-08-15 |
Family
ID=26233071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97912288T ATE301724T1 (de) | 1996-10-30 | 1997-10-30 | Verfahren zur positionierung von klonen mittels molekularen kaemmens |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US6344319B1 (de) |
| EP (1) | EP0935674B1 (de) |
| JP (3) | JP4226078B2 (de) |
| AT (1) | ATE301724T1 (de) |
| AU (1) | AU4953397A (de) |
| DE (1) | DE69733958T2 (de) |
| DK (1) | DK0935674T3 (de) |
| ES (1) | ES2247623T3 (de) |
| FR (1) | FR2755149B1 (de) |
| WO (1) | WO1998018959A1 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2755149B1 (fr) * | 1996-10-30 | 1999-01-15 | Pasteur Institut | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
| US6573369B2 (en) | 1999-05-21 | 2003-06-03 | Bioforce Nanosciences, Inc. | Method and apparatus for solid state molecular analysis |
| US20020042081A1 (en) | 2000-10-10 | 2002-04-11 | Eric Henderson | Evaluating binding affinities by force stratification and force panning |
| US6696022B1 (en) * | 1999-08-13 | 2004-02-24 | U.S. Genomics, Inc. | Methods and apparatuses for stretching polymers |
| US6897015B2 (en) | 2000-03-07 | 2005-05-24 | Bioforce Nanosciences, Inc. | Device and method of use for detection and characterization of pathogens and biological materials |
| CA2403874A1 (en) * | 2000-03-28 | 2001-12-06 | Dana-Farber Cancer Institute, Inc. | Molecular database for antibody characterization |
| US7008769B2 (en) | 2000-08-15 | 2006-03-07 | Bioforce Nanosciences, Inc. | Nanoscale molecular arrayer |
| US20020197639A1 (en) * | 2001-06-08 | 2002-12-26 | Shia Michael A. | Methods and products for analyzing nucleic acids based on methylation status |
| IL159482A0 (en) * | 2001-06-22 | 2004-06-01 | Univ Geneve | Method for detecting diseases caused by chromosomal imbalances |
| WO2003025540A2 (en) * | 2001-09-18 | 2003-03-27 | U.S. Genomics, Inc. | Differential tagging of polymers for high resolution linear analysis |
| US7042488B2 (en) | 2001-09-27 | 2006-05-09 | Fujinon Corporation | Electronic endoscope for highlighting blood vessel |
| US7371520B2 (en) * | 2002-05-28 | 2008-05-13 | U.S. Genomics, Inc. | Methods and apparati using single polymer analysis |
| US7282330B2 (en) * | 2002-05-28 | 2007-10-16 | U.S. Genomics, Inc. | Methods and apparati using single polymer analysis |
| US6952651B2 (en) * | 2002-06-17 | 2005-10-04 | Intel Corporation | Methods and apparatus for nucleic acid sequencing by signal stretching and data integration |
| NL1021160C2 (nl) * | 2002-07-26 | 2004-01-27 | Multigen Internat B V | Werkwijze voor het bepalen van het kopieaantal van een nucleotidevolgorde. |
| WO2004038037A2 (en) * | 2002-09-20 | 2004-05-06 | Intel Corporation | Controlled alignment of nano-barcodes encoding specific information for scanning probe microscopy (spm) reading |
| US7361821B2 (en) | 2002-09-20 | 2008-04-22 | Intel Corporation | Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading |
| US7606403B2 (en) | 2002-10-17 | 2009-10-20 | Intel Corporation | Model-based fusion of scanning probe microscopic images for detection and identification of molecular structures |
| US7704687B2 (en) * | 2002-11-15 | 2010-04-27 | The Johns Hopkins University | Digital karyotyping |
| KR20050100367A (ko) | 2003-01-02 | 2005-10-18 | 바이오포스 나노사이언스, 인크. | 소용적 샘플 내의 분자 분석용 방법 및 장치 |
| US20050123944A1 (en) * | 2003-08-01 | 2005-06-09 | U.S. Genomics, Inc. | Methods and compositions related to the use of sequence-specific endonucleases for analyzing nucleic acids under non-cleaving conditions |
| US20050064435A1 (en) * | 2003-09-24 | 2005-03-24 | Xing Su | Programmable molecular barcodes |
| US20050147976A1 (en) * | 2003-12-29 | 2005-07-07 | Xing Su | Methods for determining nucleotide sequence information |
| US20050151126A1 (en) * | 2003-12-31 | 2005-07-14 | Intel Corporation | Methods of producing carbon nanotubes using peptide or nucleic acid micropatterning |
| WO2005089524A2 (en) * | 2004-03-19 | 2005-09-29 | U.S. Genomics, Inc. | Compositions and methods for detection of single molecules |
| US7736818B2 (en) | 2004-12-27 | 2010-06-15 | Inphase Technologies, Inc. | Holographic recording medium and method of making it |
| JP4656145B2 (ja) * | 2005-09-05 | 2011-03-23 | 株式会社島津製作所 | 生体高分子固定用基板及びそれを用いた生体高分子固定方法 |
| JP5700911B2 (ja) | 2005-12-23 | 2015-04-15 | ナノストリング テクノロジーズ,インコーポレーテッド | 配向され、固定化された巨大分子を含む組成物とその製造法 |
| WO2007076128A2 (en) | 2005-12-23 | 2007-07-05 | Nanostring Technologies, Inc. | Nanoreporters and methods of manufacturing and use thereof |
| US20100285993A1 (en) * | 2006-02-14 | 2010-11-11 | Gregory Prelich | Systematic Genomic Library and Uses Thereof |
| CA2653095C (en) * | 2006-05-22 | 2013-07-16 | Nanostring Technologies, Inc. | Systems and methods for analyzing nanoreporters |
| EP3978121A1 (de) | 2006-07-19 | 2022-04-06 | BioNano Genomics, Inc. | Nanodüsen-geräteanordnungen: ihre herstellung und verwendung zur makromolekularen analyse |
| JP5211790B2 (ja) * | 2007-03-26 | 2013-06-12 | 住友化学株式会社 | Dnaメチル化測定方法 |
| EP2604344A3 (de) * | 2007-03-28 | 2014-07-16 | BioNano Genomics, Inc. | Verfahren zur makromolekularen Analyse mittels Nanokanalanordnungen |
| CA2687292C (en) * | 2007-04-10 | 2017-07-04 | Nanostring Technologies, Inc. | Methods and computer systems for identifying target-specific sequences for use in nanoreporters |
| JP5260981B2 (ja) * | 2008-02-22 | 2013-08-14 | 株式会社日立ハイテクノロジーズ | 真空処理装置 |
| US8628919B2 (en) | 2008-06-30 | 2014-01-14 | Bionano Genomics, Inc. | Methods and devices for single-molecule whole genome analysis |
| JP2010068800A (ja) * | 2008-08-19 | 2010-04-02 | Sumitomo Chemical Co Ltd | Dnaを定量又は検出する方法 |
| EP2175037B1 (de) | 2008-09-26 | 2017-10-11 | Genomic Vision | Verfahren zur Analyse von D4Z4-Tandemwiederholungsarrays von Nukleinsäure und Kit dafür |
| CN108467887A (zh) | 2008-11-18 | 2018-08-31 | 生物纳米基因公司 | 多核苷酸作图和测序 |
| US8709717B2 (en) | 2009-04-03 | 2014-04-29 | Illumina, Inc. | Generation of uniform fragments of nucleic acids using patterned substrates |
| JP2013524806A (ja) * | 2010-04-23 | 2013-06-20 | ゲノミク ビジョン | 分子コーミングを用いるゲノムdna及び感染性ウイルスdnaの検出によるウイルス感染の診断 |
| US20120076871A1 (en) | 2010-09-24 | 2012-03-29 | Genomic Vision Sa | Method for detecting, quantifying and mapping damage and/or repair of dna strands |
| EP2714931A1 (de) | 2011-06-03 | 2014-04-09 | Genomic Vision | Beurteilung des krebsrisikos auf der basis von rnu2-cnv und wechselwirkung zwischen rnu2 und brca1 |
| JP2014535050A (ja) * | 2011-10-31 | 2014-12-25 | ゲノミク ビジョン | 生体試料におけるゲノム再編成を特定又は検出する方法 |
| US9028776B2 (en) | 2012-04-18 | 2015-05-12 | Toxic Report Llc | Device for stretching a polymer in a fluid sample |
| AU2014278152A1 (en) | 2013-06-14 | 2015-12-24 | Nanostring Technologies, Inc. | Multiplexable tag-based reporter system |
| WO2018091971A1 (en) | 2016-11-15 | 2018-05-24 | Genomic Vision | Method for the monitoring of modified nucleases induced-gene editing events by molecular combing |
| CN110199031A (zh) | 2016-11-29 | 2019-09-03 | 基因组影像公司 | 设计用于分析感兴趣的遗传区域中的特定事件的一组多核苷酸序列的方法 |
| SG11202004649SA (en) * | 2017-11-29 | 2020-06-29 | Xgenomes Corp | Sequencing of nucleic acids by emergence |
| EP3976828A4 (de) * | 2019-05-29 | 2023-06-28 | XGenomes Corp. | Sequenzierung nach emergenz |
| CN115997030A (zh) | 2020-04-30 | 2023-04-21 | 德迈逊科技有限公司 | 用于大分子操作的装置和方法 |
| CN116171331A (zh) | 2020-06-01 | 2023-05-26 | 德迈逊科技有限公司 | 用于基因组分析的装置和方法 |
| CN115803460A (zh) | 2020-08-10 | 2023-03-14 | 德迈逊科技有限公司 | 用于多维基因组分析的装置和方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5079169A (en) * | 1990-05-22 | 1992-01-07 | The Regents Of The Stanford Leland Junior University | Method for optically manipulating polymer filaments |
| JP3123249B2 (ja) * | 1991-09-10 | 2001-01-09 | 株式会社日立製作所 | Dna分子の長さ計測方法および計測装置 |
| EP1134293A3 (de) * | 1992-03-04 | 2004-01-07 | The Regents of The University of California | Vergleichende Genomhybridisierung |
| WO1994016104A1 (en) * | 1993-01-08 | 1994-07-21 | Ctrc Research Foundation | Color imaging system for use in molecular biology |
| US5472842A (en) * | 1993-10-06 | 1995-12-05 | The Regents Of The University Of California | Detection of amplified or deleted chromosomal regions |
| WO1995014106A2 (en) | 1993-11-17 | 1995-05-26 | Id Biomedical Corporation | Cycling probe cleavage detection of nucleic acid sequences |
| FR2716263B1 (fr) | 1994-02-11 | 1997-01-17 | Pasteur Institut | Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon. |
| US5830645A (en) * | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
| US5851769A (en) * | 1995-09-27 | 1998-12-22 | The Regents Of The University Of California | Quantitative DNA fiber mapping |
| JP2000500021A (ja) * | 1995-11-13 | 2000-01-11 | アンスティテュ、パストゥール | コームドdna繊維との超高解析度比較核酸ハイブリッド形成 |
| FR2755149B1 (fr) * | 1996-10-30 | 1999-01-15 | Pasteur Institut | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
-
1997
- 1997-03-13 FR FR9702999A patent/FR2755149B1/fr not_active Expired - Lifetime
- 1997-10-30 ES ES97912288T patent/ES2247623T3/es not_active Expired - Lifetime
- 1997-10-30 AU AU49533/97A patent/AU4953397A/en not_active Abandoned
- 1997-10-30 DE DE69733958T patent/DE69733958T2/de not_active Expired - Lifetime
- 1997-10-30 AT AT97912288T patent/ATE301724T1/de active
- 1997-10-30 WO PCT/FR1997/001949 patent/WO1998018959A1/fr not_active Ceased
- 1997-10-30 US US09/297,302 patent/US6344319B1/en not_active Expired - Lifetime
- 1997-10-30 JP JP52013998A patent/JP4226078B2/ja not_active Expired - Lifetime
- 1997-10-30 EP EP97912288A patent/EP0935674B1/de not_active Expired - Lifetime
- 1997-10-30 DK DK97912288T patent/DK0935674T3/da active
-
2001
- 2001-08-03 US US09/921,302 patent/US20020048767A1/en not_active Abandoned
-
2003
- 2003-03-11 US US10/386,354 patent/US7368234B2/en not_active Expired - Fee Related
-
2007
- 2007-11-15 JP JP2007297006A patent/JP4223539B2/ja not_active Expired - Lifetime
- 2007-11-15 JP JP2007296974A patent/JP4223538B2/ja not_active Expired - Lifetime
-
2008
- 2008-03-18 US US12/076,408 patent/US7732143B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20040033510A1 (en) | 2004-02-19 |
| JP4223538B2 (ja) | 2009-02-12 |
| FR2755149B1 (fr) | 1999-01-15 |
| JP4223539B2 (ja) | 2009-02-12 |
| DE69733958D1 (de) | 2005-09-15 |
| US6344319B1 (en) | 2002-02-05 |
| AU4953397A (en) | 1998-05-22 |
| US20020048767A1 (en) | 2002-04-25 |
| FR2755149A1 (fr) | 1998-04-30 |
| JP2001507929A (ja) | 2001-06-19 |
| DE69733958T2 (de) | 2006-05-18 |
| JP2008067716A (ja) | 2008-03-27 |
| ES2247623T3 (es) | 2006-03-01 |
| EP0935674A1 (de) | 1999-08-18 |
| WO1998018959A1 (fr) | 1998-05-07 |
| JP4226078B2 (ja) | 2009-02-18 |
| US20090123926A1 (en) | 2009-05-14 |
| US7368234B2 (en) | 2008-05-06 |
| EP0935674B1 (de) | 2005-08-10 |
| US7732143B2 (en) | 2010-06-08 |
| JP2008061651A (ja) | 2008-03-21 |
| DK0935674T3 (da) | 2005-12-05 |
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