ATE170506T1 - Deuteriertes sevofluran als inhalationsbetäubungsmittel - Google Patents
Deuteriertes sevofluran als inhalationsbetäubungsmittelInfo
- Publication number
- ATE170506T1 ATE170506T1 AT94909511T AT94909511T ATE170506T1 AT E170506 T1 ATE170506 T1 AT E170506T1 AT 94909511 T AT94909511 T AT 94909511T AT 94909511 T AT94909511 T AT 94909511T AT E170506 T1 ATE170506 T1 AT E170506T1
- Authority
- AT
- Austria
- Prior art keywords
- inhalation anesthetic
- sevoflurane
- deuterated
- deuterated sevoflurane
- relates
- Prior art date
Links
- DFEYYRMXOJXZRJ-UHFFFAOYSA-N sevoflurane Chemical class FCOC(C(F)(F)F)C(F)(F)F DFEYYRMXOJXZRJ-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003983 inhalation anesthetic agent Substances 0.000 title abstract 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- 229940126062 Compound A Drugs 0.000 abstract 1
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 125000004785 fluoromethoxy group Chemical group [H]C([H])(F)O* 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229960002078 sevoflurane Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1026493A | 1993-01-28 | 1993-01-28 | |
| US08/076,582 US5391579A (en) | 1993-01-28 | 1993-06-14 | Deuterated sevoflurane as an inhalational anesthetic |
| US08/079,165 US5492111A (en) | 1993-01-28 | 1993-08-12 | Method of elimination of volatile degradation products of sevoflurane during anesthesia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE170506T1 true ATE170506T1 (de) | 1998-09-15 |
Family
ID=27359193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94909511T ATE170506T1 (de) | 1993-01-28 | 1994-01-25 | Deuteriertes sevofluran als inhalationsbetäubungsmittel |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0682649B1 (de) |
| JP (1) | JPH08509206A (de) |
| AT (1) | ATE170506T1 (de) |
| AU (1) | AU6233494A (de) |
| CA (1) | CA2155002A1 (de) |
| DE (1) | DE69413005T2 (de) |
| ES (1) | ES2122246T3 (de) |
| WO (1) | WO1994017016A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10129832A1 (de) * | 2001-06-17 | 2003-07-10 | Berolina Drug Dev Ab Svedala | Deuterierte N- und alpha-substituierte Diphenylalkoxyessigsäureaminoalkylester sowie diese Verbindungen enthaltende Arzneimittel |
| CN107226769A (zh) * | 2017-06-19 | 2017-10-03 | 郑州泰基鸿诺医药股份有限公司 | 一种含二氟氘代甲氧（硫）基官能团的芳香类化合物的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3683092A (en) | 1970-07-31 | 1972-08-08 | Baxter Laboratories Inc | Method of anesthesia |
| US4153636A (en) * | 1977-01-17 | 1979-05-08 | The Dow Chemical Company | Deuterated analogues of methoxyflurane useful as an anesthetic |
| US4154971A (en) * | 1977-06-06 | 1979-05-15 | The Dow Chemical Company | Deuterated 1,1-difluoro-2,2-dihaloethyl difluoromethyl ethers |
| US4220664A (en) * | 1979-01-29 | 1980-09-02 | The Dow Chemical Company | Deuterated isoflurane as an anesthetic agent |
-
1994
- 1994-01-25 CA CA002155002A patent/CA2155002A1/en not_active Abandoned
- 1994-01-25 JP JP6517363A patent/JPH08509206A/ja active Pending
- 1994-01-25 AT AT94909511T patent/ATE170506T1/de not_active IP Right Cessation
- 1994-01-25 EP EP94909511A patent/EP0682649B1/de not_active Expired - Lifetime
- 1994-01-25 WO PCT/US1994/001050 patent/WO1994017016A1/en not_active Ceased
- 1994-01-25 DE DE69413005T patent/DE69413005T2/de not_active Expired - Fee Related
- 1994-01-25 AU AU62334/94A patent/AU6233494A/en not_active Abandoned
- 1994-01-25 ES ES94909511T patent/ES2122246T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69413005T2 (de) | 1999-05-06 |
| ES2122246T3 (es) | 1998-12-16 |
| DE69413005D1 (de) | 1998-10-08 |
| JPH08509206A (ja) | 1996-10-01 |
| EP0682649A1 (de) | 1995-11-22 |
| CA2155002A1 (en) | 1994-08-04 |
| WO1994017016A1 (en) | 1994-08-04 |
| AU6233494A (en) | 1994-08-15 |
| EP0682649B1 (de) | 1998-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |