ATE173829T1 - Turbidimetrisches immunassay mit messung der geschwindigkeit der trübungsveränderung nach dem anfang der immunpräzipitationsreaktion - Google Patents

Turbidimetrisches immunassay mit messung der geschwindigkeit der trübungsveränderung nach dem anfang der immunpräzipitationsreaktion

Info

Publication number
ATE173829T1
ATE173829T1 AT93912327T AT93912327T ATE173829T1 AT E173829 T1 ATE173829 T1 AT E173829T1 AT 93912327 T AT93912327 T AT 93912327T AT 93912327 T AT93912327 T AT 93912327T AT E173829 T1 ATE173829 T1 AT E173829T1
Authority
AT
Austria
Prior art keywords
analyte
turbidimetric
immunoprecipitation
initial
response
Prior art date
Application number
AT93912327T
Other languages
English (en)
Inventor
Elizabeth K Kearns
Chan S Oh
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Application granted granted Critical
Publication of ATE173829T1 publication Critical patent/ATE173829T1/de

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/272—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AT93912327T 1992-07-17 1993-04-21 Turbidimetrisches immunassay mit messung der geschwindigkeit der trübungsveränderung nach dem anfang der immunpräzipitationsreaktion ATE173829T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/916,519 US5371021A (en) 1992-07-17 1992-07-17 Initial rate photometric method for immunoassay

Publications (1)

Publication Number Publication Date
ATE173829T1 true ATE173829T1 (de) 1998-12-15

Family

ID=25437408

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93912327T ATE173829T1 (de) 1992-07-17 1993-04-21 Turbidimetrisches immunassay mit messung der geschwindigkeit der trübungsveränderung nach dem anfang der immunpräzipitationsreaktion

Country Status (9)

Country Link
US (2) US5371021A (de)
EP (1) EP0604606B1 (de)
JP (1) JPH06511088A (de)
AT (1) ATE173829T1 (de)
AU (1) AU669904B2 (de)
CA (1) CA2116687A1 (de)
DE (1) DE69322242T2 (de)
ES (1) ES2125982T3 (de)
WO (1) WO1994002853A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284472B1 (en) 1998-10-05 2001-09-04 Dade Behring Inc. Method for extending the range of an immunoassay
US20060141470A1 (en) * 2003-02-14 2006-06-29 Kalayoglu Murat V Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
ITMI20030971A1 (it) * 2003-05-15 2004-11-16 Solvay Solexis Spa Preparazione di perfluoropolieteri aventi almeno un terminale -ch2oh oppure -ch(cf3)oh.
EP1496362B1 (de) * 2003-07-09 2006-12-13 Matsushita Electric Industrial Co., Ltd. Turbidimetrisches Immuntestverfahren und zugehörige Vorrichtung
JPWO2005052583A1 (ja) * 2003-11-28 2007-06-21 オリンパス株式会社 分析対象物質の検出方法
GB2426050A (en) * 2005-05-09 2006-11-15 Orion Diagnostica Oy Method of measuring binding rate using sonication
WO2007111851A1 (en) * 2006-03-24 2007-10-04 Aokin Ag Use of additives to lower the rate of a binding reaction
EP2469282A1 (de) * 2006-09-08 2012-06-27 University of Oxford Klinische Diagnose von Leberfibrose mithilfe einer neuartigen Tafel von menschlichen Serumprotein-Biomarkern
JP5813630B2 (ja) * 2009-05-14 2015-11-17 ザ チャンセラー，マスターズ アンド スカラーズ オブ ザ ユニバーシティ オブ オックスフォード 微量ヒト血漿タンパク質バイオマーカーの新規なパネルを使用した肝線維症の臨床診断
RU2650424C1 (ru) * 2017-02-27 2018-04-13 Акционерное Общество "Концерн "Океанприбор" Концентратомер подвижных инфузорий в жидких средах

Family Cites Families (25)

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Publication number Priority date Publication date Assignee Title
US4305665A (en) * 1975-01-29 1981-12-15 Baxter Travenol Laboratories, Inc. Nephelometer and nephelometer method for assaying immunochemical complex
US4268171A (en) * 1977-07-18 1981-05-19 Beckman Instruments, Inc. Method determining concentration in rate nephelometric immunochemical analysis
JPS54108693A (en) * 1978-02-14 1979-08-25 Mitsubishi Chem Ind Method and device for optically measuring antigennantibody reaction
JPS54109494A (en) * 1978-02-16 1979-08-28 Teikoku Hormone Mfg Co Ltd Method of measuring antigennantibody reaction
US4204837A (en) * 1978-03-14 1980-05-27 Beckman Instruments, Inc. Method of rate immunonephelometric analysis
US4205954A (en) * 1978-05-26 1980-06-03 Warner-Lambert Company Kinetic latex agglutinometry
JPS5544903A (en) * 1978-09-26 1980-03-29 Chugai Pharmaceut Co Ltd Method of quantitatively analyzing low molecular substance in humor
DE2901327B1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Verfahren zur Bestimmung eines opsonierenden oberflaechenbindenden alpha?-Glykoproteins
JPS57175957A (en) * 1981-04-24 1982-10-29 Chugai Pharmaceut Co Ltd Measuring method and device for antigen- antibody reaction
US4604365A (en) * 1981-06-02 1986-08-05 Electro-Nucleonics, Inc. Immunoprecipitation assay
US4766083A (en) * 1982-04-04 1988-08-23 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
DE3212658C3 (de) * 1982-04-05 1993-08-19 American Hospital Supply Corp Verfahren zur antigen-bestimmung
US4521521A (en) * 1983-03-11 1985-06-04 E. I. Du Pont De Nemours And Company Particle reagent size distribution measurements for immunoassay
US4554257A (en) * 1983-04-29 1985-11-19 Aladjem Frederick J Assaying immunoreactive and like substances by measurement of aggregate classes
JPH0736016B2 (ja) * 1984-05-11 1995-04-19 和光純薬工業株式会社 免疫グロブリンの定量方法
US4647544A (en) * 1984-06-25 1987-03-03 Nicoli David F Immunoassay using optical interference detection
DE3615384A1 (de) * 1985-05-08 1986-11-13 Nissui Seiyaku K.K., Tokio/Tokyo Verfahren zur bestimmung des rheumafaktors und denaturiertes, menschliches (gamma)-globulin fuer das verfahren
JPH0660901B2 (ja) * 1985-08-30 1994-08-10 東ソー株式会社 酵素免疫測定法
DE3684707D1 (de) * 1985-12-23 1992-05-07 Beckman Instruments Inc Verfahren und vorrichtung zur automatischen analysierung fuer immunchemie.
US4835110A (en) * 1985-12-23 1989-05-30 Beckman Instruments, Inc. Method for enhancing analysis timing in kinetic nephelometry
US5169757A (en) * 1987-05-20 1992-12-08 Carleton University Antibodies or antigens bound to a macroporous hydrophobic synthetic polymer cloth for immunological techniques
JPH02500133A (ja) * 1987-07-21 1990-01-18 クールター・エレクトロニクス・インコーポレーテッド ハプテンについての改良濁り測定抑制検定法
EP0315317B2 (de) * 1987-09-30 2000-05-10 Beckman Instruments, Inc. Aus zwei Verzahnungen bestehendes Konjugat und Verfahren zu seiner Verwendung
US5019999A (en) * 1988-09-30 1991-05-28 Technicon Instruments Corporation Immunoanalysis method for discriminating between antigen excess and antibody excess conditions
DE3900493A1 (de) * 1989-01-10 1990-07-12 Thomae Gmbh Dr K Verfahren zur bestimmung der fibrinolytischen gesamtaktivitaet im plasma

Also Published As

Publication number Publication date
DE69322242D1 (de) 1999-01-07
DE69322242T2 (de) 1999-04-22
AU669904B2 (en) 1996-06-27
JPH06511088A (ja) 1994-12-08
CA2116687A1 (en) 1994-02-03
EP0604606B1 (de) 1998-11-25
ES2125982T3 (es) 1999-03-16
US5583055A (en) 1996-12-10
EP0604606A1 (de) 1994-07-06
US5371021A (en) 1994-12-06
AU4291393A (en) 1994-02-14
WO1994002853A1 (en) 1994-02-03

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