ATE175194T1 - (e)-20(22)-dehydrovitamin-d-verbindungen - Google Patents

(e)-20(22)-dehydrovitamin-d-verbindungen

Info

Publication number: ATE175194T1
Authority: AT; Austria
Prior art keywords: compounds; dehydrovitamin; treatment; diseases; osteoporosis
Prior art date: 1993-11-03

Application number

AT94931429T

Other languages

English (en)

Inventor

Hector F Deluca

Rafal R Sicinski

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-03

Filing date

1994-10-19

Publication date

1999-01-15

1994-10-19 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1999-01-15 Application granted granted Critical

1999-01-15 Publication of ATE175194T1 publication Critical patent/ATE175194T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 3
201000010099 disease Diseases 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
208000001132 Osteoporosis Diseases 0.000 abstract 1
201000004681 Psoriasis Diseases 0.000 abstract 1
229930003316 Vitamin D Natural products 0.000 abstract 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
230000002159 abnormal effect Effects 0.000 abstract 1
230000024245 cell differentiation Effects 0.000 abstract 1
230000004663 cell proliferation Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
230000011164 ossification Effects 0.000 abstract 1
235000019166 vitamin D Nutrition 0.000 abstract 1
239000011710 vitamin D Substances 0.000 abstract 1
229940046008 vitamin d Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT94931429T 1993-11-03 1994-10-19 (e)-20(22)-dehydrovitamin-d-verbindungen ATE175194T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/147,663 US5565589A (en)	1993-11-03	1993-11-03	17-formyl-5,6-trans-vitamin D compounds

Publications (1)

Publication Number	Publication Date
ATE175194T1 true ATE175194T1 (de)	1999-01-15

Family

ID=22522410

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94931429T ATE175194T1 (de)	1993-11-03	1994-10-19	(e)-20(22)-dehydrovitamin-d-verbindungen

Country Status (10)

Country	Link
US (5)	US5565589A (de)
EP (1)	EP0726892B1 (de)
JP (1)	JPH09504549A (de)
AT (1)	ATE175194T1 (de)
AU (1)	AU8051594A (de)
DE (1)	DE69415690T2 (de)
DK (1)	DK0726892T3 (de)
ES (1)	ES2126157T3 (de)
GR (1)	GR3029449T3 (de)
WO (1)	WO1995012575A1 (de)

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US7122533B2 (en) *	1999-11-29	2006-10-17	The United States Of America As Represented By The Department Of Health And Human Services	Cosalane compounds and methods for their use
US20010044431A1 (en) *	2000-03-21	2001-11-22	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
AU6527201A (en)	2000-05-31	2001-12-11	Wisconsin Alumni Res Found	2-ethyl and 2-ethylidene-19-nor-vitamin d compounds
US7491711B2 (en) *	2001-09-21	2009-02-17	Roche Palo Alto Llc	Methods of treatment using 3-desoxy vitamin D3 analogs
US20030195175A1 (en) *	2002-03-25	2003-10-16	Deluca Hector F.	Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone
EP1613588B1 (de) *	2003-04-10	2012-05-09	Wisconsin Alumni Research Foundation	2-propyliden-19-nor-vitamin d verbindungen
CA2586679A1 (en)	2004-11-12	2006-05-18	Bioxell Spa	Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
US7448750B2 (en) *	2006-09-22	2008-11-11	Oakley, Inc.	Quadrilateral lens
AU2009266816B2 (en) *	2008-07-03	2014-09-18	Oakley, Inc.	Floating lens mounting system
CN102264751A (zh) *	2008-11-26	2011-11-30	赛特克罗公司	合成维生素d类似物的方法
US8469510B2 (en)	2009-01-09	2013-06-25	Oakley, Inc.	Eyewear with enhanced ballistic resistance
US8192015B2 (en)	2009-01-09	2012-06-05	Oakley, Inc.	Eyeglass with enhanced ballistic resistance
SG2014006324A (en)	2009-01-27	2014-03-28	Berg Llc	Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
CN102655869B (zh)	2009-08-14	2016-08-10	博格有限责任公司	用于治疗脱发的维生素d3及其类似物
US8881316B2 (en)	2010-03-19	2014-11-11	Oakley, Inc.	Eyewear with rigid lens support
US8668330B2 (en)	2010-08-13	2014-03-11	Oakley, Inc.	Eyewear with lens retention mechanism
US9188792B2 (en)	2011-09-22	2015-11-17	Oakley, Inc.	Mounting mechanism for eyewear
US9122078B2 (en)	2011-12-01	2015-09-01	Oakley, Inc.	Releasable earstem mounting mechanism for eyewear
CN205007112U (zh)	2012-08-31	2016-02-03	奥克利有限公司	具有多个通风状态的眼睛佩戴物及眼睛佩戴物附件
US10357400B2 (en)	2012-12-11	2019-07-23	Oakley, Inc.	Eyewear with outriggers
WO2014138159A1 (en)	2013-03-07	2014-09-12	Oakley, Inc.	Regeneratable ant-fogging element for goggle
HK1222819A1 (zh)	2013-05-29	2017-07-14	博格有限责任公司	使用维生素d预防或减轻化疗诱发的脱发
AU2015235947B2 (en)	2014-03-27	2017-12-07	Oakley, Inc.	Mounting mechanism for eyewear
US10687981B2 (en)	2015-10-09	2020-06-23	Oakley, Inc.	Headworn supports with passive venting and removable lens
US9709817B2 (en)	2015-12-07	2017-07-18	Oakley, Inc.	Eyewear retention devices and methods
US10156734B2 (en)	2015-12-08	2018-12-18	Oakley, Inc.	Eyewear traction devices and methods
US10359642B2 (en)	2016-04-22	2019-07-23	Oakley, Inc.	Mounting mechanism for eyewear
CN114685337B (zh) *	2022-04-24	2023-08-29	浙江花园生物高科股份有限公司	一种艾地骨化醇的制备方法

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FR570829A (fr) *	1923-09-14	1924-05-07	Anciens Etablissements R Corne	Dispositif de commande du mouvement d'écartement et de rapprochement des aiguilles dans les machines à coudre et à broder faisant les ourlets et points à jour
US4172076A (en) *	1977-04-04	1979-10-23	Diamond Shamrock Corporation	Process for preparing steroidal acids and their intermediate derivatives
US4338250A (en) *	1981-04-27	1982-07-06	Wisconsin Alumni Research Foundation	1-Hydroxylation process
US4769181A (en) *	1983-11-07	1988-09-06	Wisconsin Alumni Research Foundation	1,25-dihydroxyvitamin D2 compounds
US4857518A (en) *	1984-10-04	1989-08-15	Wisconsin Alumni Research Foundation	Hydroxylated 24-homo-vitamin D derivatives and methods for preparing same
DE3577552D1 (de) *	1984-11-27	1990-06-13	Chugai Pharmaceutical Co Ltd	Vitamin d-derivate und verfahren zu deren herstellung.
WO1987000834A1 (en) *	1985-08-02	1987-02-12	Leo Pharmaceutical Products Ltd. A/S	Novel vitamin d analogues
JPH0755960B2 (ja) *	1986-11-14	1995-06-14	日清製粉株式会社	ステロイド誘導体およびその製造方法
EP0412110B1 (de) *	1988-04-21	1993-07-07	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab)	Vitamin d analoge
US5250523A (en) *	1988-04-29	1993-10-05	Wisconsin Alumni Research Foundation	Side chain unsaturated 1α-hydroxyvitanim D homologs
RU2057117C1 (ru)	1988-04-29	1996-03-27	Висконсин Алюмни Рисерч Фаундейшн	ГОМОЛОГИ 1α - ГИДРОКСИВИТАМИНА D3 С НЕНАСЫЩЕННОЙ БОКОВОЙ ЦЕПЬЮ, КОМПОЗИЦИЯ, СПОСОБСТВУЮЩАЯ СТИМУЛЯЦИИ И УСИЛЕНИЮ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА, СПОСОБ СТИМУЛЯЦИИ И УСИЛЕНИЯ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА
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US4973584A (en) *	1989-03-09	1990-11-27	Deluca Hector F	Novel 1α-hydroxyvitamin D2 epimer and derivatives
US5401731A (en) *	1989-06-29	1995-03-28	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab)	Vitamin D analogues
US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5089641A (en) *	1991-03-11	1992-02-18	Wisconsin Alumni Research Foundation	Synthesis of 1α-hydroxy-secosterol compounds
US5206230A (en) *	1991-06-05	1993-04-27	Daikin Industries, Ltd.	Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
DK0521550T3 (da) *	1991-07-05	1996-11-04	Duphar Int Res	Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derfor
US5182393A (en) *	1991-08-09	1993-01-26	Hoffmann-La Roche Inc.	Process for precursors to calcitriol and related compounds

1993
- 1993-11-03 US US08/147,663 patent/US5565589A/en not_active Expired - Fee Related
1994
- 1994-10-19 AT AT94931429T patent/ATE175194T1/de not_active IP Right Cessation
- 1994-10-19 DE DE69415690T patent/DE69415690T2/de not_active Expired - Fee Related
- 1994-10-19 DK DK94931429T patent/DK0726892T3/da active
- 1994-10-19 JP JP7513253A patent/JPH09504549A/ja active Pending
- 1994-10-19 EP EP94931429A patent/EP0726892B1/de not_active Expired - Lifetime
- 1994-10-19 WO PCT/US1994/012084 patent/WO1995012575A1/en not_active Ceased
- 1994-10-19 ES ES94931429T patent/ES2126157T3/es not_active Expired - Lifetime
- 1994-10-19 AU AU80515/94A patent/AU8051594A/en not_active Abandoned
1995
- 1995-05-16 US US08/441,827 patent/US5536828A/en not_active Expired - Fee Related
- 1995-05-16 US US08/442,463 patent/US5484781A/en not_active Expired - Fee Related
- 1995-05-16 US US08/442,473 patent/US5484782A/en not_active Expired - Fee Related
- 1995-05-16 US US08/441,775 patent/US5488044A/en not_active Expired - Fee Related
1999
- 1999-02-19 GR GR990400534T patent/GR3029449T3/el unknown

Also Published As

Publication number	Publication date
DE69415690D1 (de)	1999-02-11
ES2126157T3 (es)	1999-03-16
AU8051594A (en)	1995-05-23
US5488044A (en)	1996-01-30
US5536828A (en)	1996-07-16
US5484781A (en)	1996-01-16
GR3029449T3 (en)	1999-05-28
EP0726892A1 (de)	1996-08-21
US5565589A (en)	1996-10-15
JPH09504549A (ja)	1997-05-06
DK0726892T3 (da)	1999-08-30
WO1995012575A1 (en)	1995-05-11
DE69415690T2 (de)	1999-05-20
EP0726892B1 (de)	1998-12-30
US5484782A (en)	1996-01-16

Legal Events

Date	Code	Title	Description
1999-10-15	UEP	Publication of translation of european patent specification
2002-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DK0726892T3 (da)	1999-08-30	(E)-20(22)-dehydrovitamin D-forbindelser
CA2272745A1 (en)	1998-09-24	2-alkyl-19-nor-vitamin d compounds
MXPA02009590A (es)	2004-03-26	Compuestos de 2-alquiliden-19-norvitamina d y sus usos terapeuticos.
MY141773A (en)	2010-06-30	(methylsulfonyl)phenyl-2-(5h)-furanones as cox-2 inhibitors
CA2403232A1 (en)	2001-10-11	26,27-homologated-20-epi-2-alkyl-19-nor-vitamin d compounds
DE69628019D1 (de)	2003-06-12	Chinolone und deren therapeutische verwendung
HUT70499A (en)	1995-10-30	Fluoroalkoxybenzaldehyde derivatives and process for producing them
NO20000762D0 (no)	2000-02-16	Anvendelse av substituerte adeninderivater til behandling av multippel sklerose
AU6320394A (en)	1994-12-15	Aryl substituted heterocycles
ATE206409T1 (de)	2001-10-15	N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h- benzo(b)(1,5)-diazepin-3-yl)-acetamide
DK0667856T3 (da)	1998-09-28	Nye D-vitaminanaloger
ES2193241T3 (es)	2003-11-01	Nuevas n-2-oxo2.3.4.5-tetrajodrp-1h-1,5-benzodiazepin-3-il)-3-amidas.
ATE181056T1 (de)	1999-06-15	Arylessigsäurederivate und ihre verwendung als fungizide
DE69510338D1 (de)	1999-07-22	Azirdin-derivate, deren herstellung und verwendung
AU586808B2 (en)	1989-07-27	Purine derivatives
PL328225A1 (en)	1999-01-18	Diphenylstilbenes as pro-medications used to produce cox-2-inhibitors
RU94038063A (ru)	1996-05-27	3-фенилуреидо-азепин-2-оны и -бензазепин-2-оны, способы их получения, промежуточные соединения, фармацевтические композиции и способы лечения
ATE157660T1 (de)	1997-09-15	Hydroxymethylfurazancarbonsäurederivate und ihre verwendung in der behandlung von kardiovaskulären erkrankungen
MX9803966A (es)	1998-09-30	25-hidroxi-16-en-26,27-bishomo-colecalciferoles.
IL117295A (en)	1999-11-30	4-Aminotetrahydro-benzisoxazole or-isothiazole compounds and pharmaceutical compositions comprising them
ES2104174T3 (es)	1997-10-01	Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos.
IL112630A0 (en)	1995-05-26	Indane-2-mercaptoacetylamide disulfide derivatives useful as inhibitors or enkephalinase
AU2068895A (en)	1995-10-09	Dl- di- or tri-hydroxyphenylglycine alkyl esters for the treatment of inflammatory and allergic conditions
TNSN86165A1 (fr)	1990-01-01	Nouveaux ortho-anisamides, leur procede d'obtention et leurs applications therapeutiques
MX9603316A (es)	1997-02-28	(+)-liarozol enantiomericamente puro.