DK0726892T3 - (E)-20(22)-dehydrovitamin D-forbindelser - Google Patents

(E)-20(22)-dehydrovitamin D-forbindelser

Info

Publication number: DK0726892T3
Authority: DK; Denmark
Prior art keywords: compounds; dehydrovitamin; treatment; diseases; osteoporosis
Prior art date: 1993-11-03

Application number

DK94931429T

Other languages

Danish (da)

English (en)

Inventor

Hector F Deluca

Rafal R Sicinski

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-03

Filing date

1994-10-19

Publication date

1999-08-30

1994-10-19 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1999-08-30 Application granted granted Critical

1999-08-30 Publication of DK0726892T3 publication Critical patent/DK0726892T3/da

Links

150000001875 compounds Chemical class 0.000 title abstract 3
201000010099 disease Diseases 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
208000001132 Osteoporosis Diseases 0.000 abstract 1
201000004681 Psoriasis Diseases 0.000 abstract 1
229930003316 Vitamin D Natural products 0.000 abstract 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
230000002159 abnormal effect Effects 0.000 abstract 1
230000024245 cell differentiation Effects 0.000 abstract 1
230000004663 cell proliferation Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
230000011164 ossification Effects 0.000 abstract 1
235000019166 vitamin D Nutrition 0.000 abstract 1
239000011710 vitamin D Substances 0.000 abstract 1
229940046008 vitamin d Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK94931429T 1993-11-03 1994-10-19 (E)-20(22)-dehydrovitamin D-forbindelser DK0726892T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/147,663 US5565589A (en)	1993-11-03	1993-11-03	17-formyl-5,6-trans-vitamin D compounds
PCT/US1994/012084 WO1995012575A1 (en)	1993-11-03	1994-10-19	(e)-20(22)-dehydrovitamin d compounds

Publications (1)

Publication Number	Publication Date
DK0726892T3 true DK0726892T3 (da)	1999-08-30

Family

ID=22522410

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94931429T DK0726892T3 (da)	1993-11-03	1994-10-19	(E)-20(22)-dehydrovitamin D-forbindelser

Country Status (10)

Country	Link
US (5)	US5565589A (de)
EP (1)	EP0726892B1 (de)
JP (1)	JPH09504549A (de)
AT (1)	ATE175194T1 (de)
AU (1)	AU8051594A (de)
DE (1)	DE69415690T2 (de)
DK (1)	DK0726892T3 (de)
ES (1)	ES2126157T3 (de)
GR (1)	GR3029449T3 (de)
WO (1)	WO1995012575A1 (de)

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US20010044431A1 (en) *	2000-03-21	2001-11-22	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
CA2410880C (en) *	2000-05-31	2009-03-03	Wisconsin Alumni Research Foundation	2-ethyl and 2-ethylidene-19-nor-vitamin d compounds
US7491711B2 (en) *	2001-09-21	2009-02-17	Roche Palo Alto Llc	Methods of treatment using 3-desoxy vitamin D3 analogs
US20030195175A1 (en) *	2002-03-25	2003-10-16	Deluca Hector F.	Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone
KR20050120787A (ko) *	2003-04-10	2005-12-23	위스콘신 얼럼나이 리서어치 화운데이션	2-프로필리덴-19-노르-비타민 ｄ 화합물
EP1812011A1 (de)	2004-11-12	2007-08-01	Bioxell S.p.a.	Kombinierte verwendung von vitamin-d-derivaten und antiproliferativen mitteln zur behandlung von blasenkrebs
US7448750B2 (en) *	2006-09-22	2008-11-11	Oakley, Inc.	Quadrilateral lens
JP5676439B2 (ja)	2008-07-03	2015-02-25	オークリーインコーポレイテッド	浮遊レンズ取り付けシステム
CA2744591A1 (en) *	2008-11-26	2010-06-03	Cytochroma Inc.	Method for synthesizing vitamin d analogs
US8469510B2 (en) *	2009-01-09	2013-06-25	Oakley, Inc.	Eyewear with enhanced ballistic resistance
US8192015B2 (en)	2009-01-09	2012-06-05	Oakley, Inc.	Eyeglass with enhanced ballistic resistance
AU2010208323B2 (en)	2009-01-27	2016-03-10	Berg Llc	Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (de)	2009-08-14	2019-05-22	Berg LLC	Vitamin d3 und analoge davon zur behandlung von alopezie
SG184119A1 (en)	2010-03-19	2012-10-30	Oakley Inc	Eyewear
WO2012021863A1 (en)	2010-08-13	2012-02-16	Oakley, Inc.	Eyewear with lens retention mechanism
JP5934798B2 (ja)	2011-09-22	2016-06-15	オークリーインコーポレイテッド	アイウェアのための取り付けメカニズム
US9122078B2 (en)	2011-12-01	2015-09-01	Oakley, Inc.	Releasable earstem mounting mechanism for eyewear
WO2014036274A2 (en)	2012-08-31	2014-03-06	Oakley, Inc.	Eyewear having multiple ventilation states
GB2522389B (en)	2012-12-11	2019-07-31	Oakley Inc	Eyewear with outriggers
WO2014138159A1 (en)	2013-03-07	2014-09-12	Oakley, Inc.	Regeneratable ant-fogging element for goggle
SG10201709894RA (en)	2013-05-29	2018-01-30	Berg Llc	Preventing or mitigating chemotherapy induced alopecia using vitamin d
AU2015235947B2 (en)	2014-03-27	2017-12-07	Oakley, Inc.	Mounting mechanism for eyewear
WO2017062813A1 (en)	2015-10-09	2017-04-13	Oakley, Inc.	Headworn supports with passive venting and removable lens
US9709817B2 (en)	2015-12-07	2017-07-18	Oakley, Inc.	Eyewear retention devices and methods
EP3387485B1 (de)	2015-12-08	2025-05-07	Oakley, Inc.	Vorrichtungen und verfahren zum ziehen von brillen
US10359642B2 (en)	2016-04-22	2019-07-23	Oakley, Inc.	Mounting mechanism for eyewear
CN114685337B (zh) *	2022-04-24	2023-08-29	浙江花园生物高科股份有限公司	一种艾地骨化醇的制备方法

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FR570829A (fr) *	1923-09-14	1924-05-07	Anciens Etablissements R Corne	Dispositif de commande du mouvement d'écartement et de rapprochement des aiguilles dans les machines à coudre et à broder faisant les ourlets et points à jour
US4172076A (en) *	1977-04-04	1979-10-23	Diamond Shamrock Corporation	Process for preparing steroidal acids and their intermediate derivatives
US4338250A (en) *	1981-04-27	1982-07-06	Wisconsin Alumni Research Foundation	1-Hydroxylation process
US4769181A (en) *	1983-11-07	1988-09-06	Wisconsin Alumni Research Foundation	1,25-dihydroxyvitamin D2 compounds
US4857518A (en) *	1984-10-04	1989-08-15	Wisconsin Alumni Research Foundation	Hydroxylated 24-homo-vitamin D derivatives and methods for preparing same
CA1332841C (en) *	1984-11-27	1994-11-01	Noboru Kubodera	Vitamin d derivatives and process for producing the same
DE3666587D1 (en) *	1985-08-02	1989-11-30	Leo Pharm Prod Ltd	Novel vitamin d analogues
JPH0755960B2 (ja) *	1986-11-14	1995-06-14	日清製粉株式会社	ステロイド誘導体およびその製造方法
EP0412110B1 (de) *	1988-04-21	1993-07-07	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab)	Vitamin d analoge
US5250523A (en) *	1988-04-29	1993-10-05	Wisconsin Alumni Research Foundation	Side chain unsaturated 1α-hydroxyvitanim D homologs
JPH0699454B2 (ja)	1988-04-29	1994-12-07	ウィスコンシン・アルムナイ・リサーチ・ファウンデイション	１α―ヒドロキシビタミンＤ同族体
JPH075542B2 (ja) *	1988-09-14	1995-01-25	呉羽化学工業株式会社	ビタミンｄ▲下３▼誘導体及びその製造方法
US4973584A (en) *	1989-03-09	1990-11-27	Deluca Hector F	Novel 1α-hydroxyvitamin D2 epimer and derivatives
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US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5089641A (en) *	1991-03-11	1992-02-18	Wisconsin Alumni Research Foundation	Synthesis of 1α-hydroxy-secosterol compounds
US5206230A (en) *	1991-06-05	1993-04-27	Daikin Industries, Ltd.	Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
ES2093180T3 (es) *	1991-07-05	1996-12-16	Duphar Int Res	Compuesto de vitamina d, metodo de preparar este compuesto y producto intermedio de dicho metodo.
US5182393A (en) *	1991-08-09	1993-01-26	Hoffmann-La Roche Inc.	Process for precursors to calcitriol and related compounds

1993
- 1993-11-03 US US08/147,663 patent/US5565589A/en not_active Expired - Fee Related
1994
- 1994-10-19 ES ES94931429T patent/ES2126157T3/es not_active Expired - Lifetime
- 1994-10-19 JP JP7513253A patent/JPH09504549A/ja active Pending
- 1994-10-19 AT AT94931429T patent/ATE175194T1/de not_active IP Right Cessation
- 1994-10-19 DK DK94931429T patent/DK0726892T3/da active
- 1994-10-19 AU AU80515/94A patent/AU8051594A/en not_active Abandoned
- 1994-10-19 DE DE69415690T patent/DE69415690T2/de not_active Expired - Fee Related
- 1994-10-19 EP EP94931429A patent/EP0726892B1/de not_active Expired - Lifetime
- 1994-10-19 WO PCT/US1994/012084 patent/WO1995012575A1/en not_active Ceased
1995
- 1995-05-16 US US08/441,827 patent/US5536828A/en not_active Expired - Fee Related
- 1995-05-16 US US08/442,473 patent/US5484782A/en not_active Expired - Fee Related
- 1995-05-16 US US08/441,775 patent/US5488044A/en not_active Expired - Fee Related
- 1995-05-16 US US08/442,463 patent/US5484781A/en not_active Expired - Fee Related
1999
- 1999-02-19 GR GR990400534T patent/GR3029449T3/el unknown

Also Published As

Publication number	Publication date
AU8051594A (en)	1995-05-23
ES2126157T3 (es)	1999-03-16
US5488044A (en)	1996-01-30
US5565589A (en)	1996-10-15
ATE175194T1 (de)	1999-01-15
US5536828A (en)	1996-07-16
GR3029449T3 (en)	1999-05-28
WO1995012575A1 (en)	1995-05-11
US5484782A (en)	1996-01-16
JPH09504549A (ja)	1997-05-06
DE69415690T2 (de)	1999-05-20
EP0726892A1 (de)	1996-08-21
US5484781A (en)	1996-01-16
DE69415690D1 (de)	1999-02-11
EP0726892B1 (de)	1998-12-30

Publication	Publication Date	Title
ATE175194T1 (de)	1999-01-15	(e)-20(22)-dehydrovitamin-d-verbindungen
CA2272745A1 (en)	1998-09-24	2-alkyl-19-nor-vitamin d compounds
MY141773A (en)	2010-06-30	(methylsulfonyl)phenyl-2-(5h)-furanones as cox-2 inhibitors
CA2403232A1 (en)	2001-10-11	26,27-homologated-20-epi-2-alkyl-19-nor-vitamin d compounds
DE69628019D1 (de)	2003-06-12	Chinolone und deren therapeutische verwendung
NO20000762L (no)	1994-09-13	Anvendelse av substituerte adeninderivater til behandling av multippel sklerose
AU6320394A (en)	1994-12-15	Aryl substituted heterocycles
DK0667856T3 (da)	1998-09-28	Nye D-vitaminanaloger
ES2193241T3 (es)	2003-11-01	Nuevas n-2-oxo2.3.4.5-tetrajodrp-1h-1,5-benzodiazepin-3-il)-3-amidas.
ATE181056T1 (de)	1999-06-15	Arylessigsäurederivate und ihre verwendung als fungizide
DE69510338D1 (de)	1999-07-22	Azirdin-derivate, deren herstellung und verwendung
MX9708416A (es)	1998-02-28	Derivados de piperazino como antagonistas de neuroquininas.
AU586808B2 (en)	1989-07-27	Purine derivatives
ES2194102T3 (es)	2003-11-16	Nuevas n-(2,4-dioxo-2,3,4,5-tetrahidro-1h-1,5-benzodiazepin-3-il)-3-amidas.
PL328225A1 (en)	1999-01-18	Diphenylstilbenes as pro-medications used to produce cox-2-inhibitors
RU94038063A (ru)	1996-05-27	3-фенилуреидо-азепин-2-оны и -бензазепин-2-оны, способы их получения, промежуточные соединения, фармацевтические композиции и способы лечения
ATE157660T1 (de)	1997-09-15	Hydroxymethylfurazancarbonsäurederivate und ihre verwendung in der behandlung von kardiovaskulären erkrankungen
MX9803966A (es)	1998-09-30	25-hidroxi-16-en-26,27-bishomo-colecalciferoles.
ES2104174T3 (es)	1997-10-01	Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos.
IL112630A0 (en)	1995-05-26	Indane-2-mercaptoacetylamide disulfide derivatives useful as inhibitors or enkephalinase
AU2068895A (en)	1995-10-09	Dl- di- or tri-hydroxyphenylglycine alkyl esters for the treatment of inflammatory and allergic conditions
TNSN86165A1 (fr)	1990-01-01	Nouveaux ortho-anisamides, leur procede d'obtention et leurs applications therapeutiques
MX9603316A (es)	1997-02-28	(+)-liarozol enantiomericamente puro.
YU10397A (sh)	1999-07-28	Derivati 1,25-dihidroksi-16,22,23-trisdehidro -holekalciferola postupak za njihovu proizvodnju, njihovo korišćenje i farmaceutske smeše koje ih sadrže
HU9600300D0 (en)	1996-04-29	Thiocarbamoyl derivatives using as antimicrobial agents and process for producing of these