ATE175975T1 - Verdrängungschromatographisches verfahren und gereinigtes hämoglobin - Google Patents

Verdrängungschromatographisches verfahren und gereinigtes hämoglobin

Info

Publication number: ATE175975T1
Authority: AT; Austria
Prior art keywords: hemoglobin; column; admixtures; stage; chromatographic method
Prior art date: 1993-09-21

Application number

AT94926756T

Other languages

English (en)

Inventor

Diana Pliura

Diane Wiffen

Salman Ashraf

Anthony A Magnin

Original Assignee

Hemosol Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-21

Filing date

1994-09-20

Publication date

1999-02-15

1993-09-21 Priority claimed from CA002106612A external-priority patent/CA2106612C/en

1994-09-20 Application filed by Hemosol Inc filed Critical Hemosol Inc

1999-02-15 Application granted granted Critical

1999-02-15 Publication of ATE175975T1 publication Critical patent/ATE175975T1/de

Links

102000001554 Hemoglobins Human genes 0.000 title abstract 9
108010054147 Hemoglobins Proteins 0.000 title abstract 9
238000004587 chromatography analysis Methods 0.000 title 1
238000006073 displacement reaction Methods 0.000 title 1
230000002378 acidificating effect Effects 0.000 abstract 1
238000011097 chromatography purification Methods 0.000 abstract 1
238000004255 ion exchange chromatography Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/422—Displacement mode
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)

AT94926756T 1993-09-21 1994-09-20 Verdrängungschromatographisches verfahren und gereinigtes hämoglobin ATE175975T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CA002106612A CA2106612C (en)	1993-09-21	1993-09-21	Displacement chromatography process

Publications (1)

Publication Number	Publication Date
ATE175975T1 true ATE175975T1 (de)	1999-02-15

Family

ID=4152343

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94926756T ATE175975T1 (de)	1993-09-21	1994-09-20	Verdrängungschromatographisches verfahren und gereinigtes hämoglobin

Country Status (9)

Country	Link
JP (1)	JP4057049B2 (de)
KR (1)	KR100361894B1 (de)
AT (1)	ATE175975T1 (de)
DE (1)	DE69416103T2 (de)
DK (1)	DK0668877T3 (de)
ES (1)	ES2126775T3 (de)
HU (1)	HU218159B (de)
RU (1)	RU2145873C1 (de)
UA (1)	UA35599C2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8153009B2 (en) *	2005-04-22	2012-04-10	Waters Technologies Corporation	Apparatus and methods for mass-spectrometric directed purification of biopolymers
RU2329826C1 (ru) *	2006-12-29	2008-07-27	Институт высокомолекулярных соединений РАН (ИВС РАН)	Способ получения растворов гемоглобина, очищенных от стромальных компонентов
AU2010292897B2 (en) *	2009-08-06	2016-01-07	Genentech, Inc.	Method to improve virus removal in protein purification
AU2011329053A1 (en) *	2010-11-15	2013-06-06	Biogen Inc.	Enrichment and concentration of select product isoforms by overloaded bind and elute chromatography
US10364268B2 (en)	2011-12-22	2019-07-30	Genentech, Inc.	Ion exchange membrane chromatography
TWI631132B (zh)	2013-05-06	2018-08-01	賽諾菲公司	用於純化抗體之連續多步驟方法
EP3546475A1 (de)	2018-03-27	2019-10-02	Sanofi	Volldurchflussverfahren zur reinigung rekombinanter proteine
TW202128264A (zh) *	2019-09-25	2021-08-01	瑞士商赫孚孟拉羅股份公司	使用經預測之溶離緩衝鹽濃度的陽離子層析法
CN116802206A (zh) *	2020-12-28	2023-09-22	等离子体技术有限责任公司	用于生产规模的免疫球蛋白g分离系统和方法
CN114712894B (zh) *	2022-04-08	2024-04-30	无锡博慧斯生物医药科技有限公司	一种糖化血红蛋白层析柱的活化液、活化方法和应用

1994
- 1994-09-20 DK DK94926756T patent/DK0668877T3/da active
- 1994-09-20 HU HU9501479A patent/HU218159B/hu not_active IP Right Cessation
- 1994-09-20 RU RU95112503A patent/RU2145873C1/ru not_active IP Right Cessation
- 1994-09-20 DE DE69416103T patent/DE69416103T2/de not_active Expired - Fee Related
- 1994-09-20 AT AT94926756T patent/ATE175975T1/de not_active IP Right Cessation
- 1994-09-20 JP JP50945895A patent/JP4057049B2/ja not_active Expired - Fee Related
- 1994-09-20 UA UA95058439A patent/UA35599C2/uk unknown
- 1994-09-20 ES ES94926756T patent/ES2126775T3/es not_active Expired - Lifetime
- 1994-09-21 KR KR1019950701487A patent/KR100361894B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
RU2145873C1 (ru)	2000-02-27
RU95112503A (ru)	1996-12-20
HU9501479D0 (en)	1995-07-28
ES2126775T3 (es)	1999-04-01
HUT72924A (en)	1996-06-28
UA35599C2 (uk)	2001-04-16
DE69416103T2 (de)	1999-08-05
JP4057049B2 (ja)	2008-03-05
JPH08503714A (ja)	1996-04-23
KR100361894B1 (ko)	2003-05-12
HU218159B (hu)	2000-06-28
DE69416103D1 (de)	1999-03-04
DK0668877T3 (da)	1999-09-13

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Legal Events

Date	Code	Title	Description
2009-06-15	REN	Ceased due to non-payment of the annual fee