ATE175975T1 - Verdrängungschromatographisches verfahren und gereinigtes hämoglobin - Google Patents

Verdrängungschromatographisches verfahren und gereinigtes hämoglobin

Info

Publication number
ATE175975T1
ATE175975T1 AT94926756T AT94926756T ATE175975T1 AT E175975 T1 ATE175975 T1 AT E175975T1 AT 94926756 T AT94926756 T AT 94926756T AT 94926756 T AT94926756 T AT 94926756T AT E175975 T1 ATE175975 T1 AT E175975T1
Authority
AT
Austria
Prior art keywords
hemoglobin
column
admixtures
stage
chromatographic method
Prior art date
Application number
AT94926756T
Other languages
English (en)
Inventor
Diana Pliura
Diane Wiffen
Salman Ashraf
Anthony A Magnin
Original Assignee
Hemosol Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002106612A external-priority patent/CA2106612C/en
Application filed by Hemosol Inc filed Critical Hemosol Inc
Application granted granted Critical
Publication of ATE175975T1 publication Critical patent/ATE175975T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/422—Displacement mode
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT94926756T 1993-09-21 1994-09-20 Verdrängungschromatographisches verfahren und gereinigtes hämoglobin ATE175975T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002106612A CA2106612C (en) 1993-09-21 1993-09-21 Displacement chromatography process

Publications (1)

Publication Number Publication Date
ATE175975T1 true ATE175975T1 (de) 1999-02-15

Family

ID=4152343

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94926756T ATE175975T1 (de) 1993-09-21 1994-09-20 Verdrängungschromatographisches verfahren und gereinigtes hämoglobin

Country Status (9)

Country Link
JP (1) JP4057049B2 (de)
KR (1) KR100361894B1 (de)
AT (1) ATE175975T1 (de)
DE (1) DE69416103T2 (de)
DK (1) DK0668877T3 (de)
ES (1) ES2126775T3 (de)
HU (1) HU218159B (de)
RU (1) RU2145873C1 (de)
UA (1) UA35599C2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112006001012B4 (de) * 2005-04-22 2017-05-18 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Verfahren für eine auf Massenspektrometrie gerichtete Aufbereitung von Biopolymeren
RU2329826C1 (ru) * 2006-12-29 2008-07-27 Институт высокомолекулярных соединений РАН (ИВС РАН) Способ получения растворов гемоглобина, очищенных от стромальных компонентов
EP4786482A2 (de) 2009-08-06 2026-08-05 F. Hoffmann-La Roche AG Virusfiltrierungsverfahren
JP2014503495A (ja) * 2010-11-15 2014-02-13 バイオジェン アイデック インコーポレイテッド 過負荷結合および溶出クロマトグラフィによる選択生成物アイソフォームの富化および濃縮
PL2794635T3 (pl) 2011-12-22 2019-02-28 F.Hoffmann-La Roche Ag Membranowa chromatografia jonowymienna
DK2994485T3 (en) * 2013-05-06 2018-04-23 Sanofi Sa CONTINUOUS MULTIPLE STEP PROCEDURE FOR PURIFICATION OF ANTIBODIES
EP3546475A1 (de) 2018-03-27 2019-10-02 Sanofi Volldurchflussverfahren zur reinigung rekombinanter proteine
TW202128264A (zh) 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 使用經預測之溶離緩衝鹽濃度的陽離子層析法
CA3236213A1 (en) * 2021-10-27 2023-05-04 Eugene ZURLO Compositions and methods for isolating proteins
CN114712894B (zh) * 2022-04-08 2024-04-30 无锡博慧斯生物医药科技有限公司 一种糖化血红蛋白层析柱的活化液、活化方法和应用

Also Published As

Publication number Publication date
HUT72924A (en) 1996-06-28
KR100361894B1 (ko) 2003-05-12
RU2145873C1 (ru) 2000-02-27
DE69416103D1 (de) 1999-03-04
ES2126775T3 (es) 1999-04-01
RU95112503A (ru) 1996-12-20
HU9501479D0 (en) 1995-07-28
HU218159B (hu) 2000-06-28
DK0668877T3 (da) 1999-09-13
JP4057049B2 (ja) 2008-03-05
JPH08503714A (ja) 1996-04-23
UA35599C2 (uk) 2001-04-16
DE69416103T2 (de) 1999-08-05

Similar Documents

Publication Publication Date Title
GR3032728T3 (en) Purification of alpha-1 proteinase inhibitor using novel chromatographic separation conditions
DE69907439D1 (de) Reinigung von proteinen durch ionenaustauschchromatographie
BR9916101A (pt) Purificação de compostos de ciclopeptìdeos equinocandinos
SE9603068D0 (sv) Process for purifying a protein
DE69416103D1 (de) Verdrängungschromatographisches verfahren und gereinigtes hämoglobin
ATE54799T1 (de) Verfahren zur spezifischen abtrennung von lactose aus milch.
UA29421C2 (uk) Спосіб виділення фактора vііі з інших білків в плазмі крові
ATE314391T1 (de) Methode zur reinigung von thrombopoietin
BR9301641A (pt) Processo para produzir uma preparacao de fator viii,altamente purificada e uso
ES2161790T3 (es) Procedimiento de separacion y de purificacion de proteinas dependientes de la vitamina k.
EP0656419A4 (de) Verfahren zur hochreinigung von menschlichem serumalbumin.
IL87543A0 (en) Interleukin 1 inhibitors,methods for the purification thereof and pharmaceutical compositions containing the same
ATE381577T1 (de) Verfahren zur aufreinigung von apolipoprotein-a oder apolipoprotein-e aus menschlichem plasma
DE69411492D1 (de) Verfahren zur Reinigung von mittleren Olefinen
EP0282363A3 (en) Method for preparation of a concentrate of alpha-1-antitrypsin from a human plasma fraction, and its use as a pharmaceutical
Hansson et al. Adsorption and desorption of proteins in metal chelate affinity chromatography: purification of albumin
WO1999009004A3 (en) Process for preparing and/or purifying amido acid phenyl ester sulfonates
ATE155481T1 (de) Verfahren zur reinigung von streptolysin 0, intaktes streptolysin 0 erhältlich nach diesem verfahren und seine verwendung
GR3025944T3 (en) Purification of factor xiii.
KR960010682A (ko) 금속이온 친화성 크로마토그라피를 이용한 히루딘의 정제방법
RU93054542A (ru) Способ определения гликированного гемоглобина в крови
JPS557006A (en) Purification of urokinase
KR930006151A (ko) 지렁이로부터 프로테아제를 분리 정제하는 방법
KR970070017A (ko) 재조합 인 과립구 콜로니 자극인자(rhG-CSF)의 정제방법
DE10045935A1 (de) Stoff aus dem Gift der Schlage Bitis gabonica rhinoceros

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee