ATE176784T1 - Verfahren zur herstellung von n- biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen - Google Patents

Verfahren zur herstellung von n- biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen

Info

Publication number
ATE176784T1
ATE176784T1 AT95931442T AT95931442T ATE176784T1 AT E176784 T1 ATE176784 T1 AT E176784T1 AT 95931442 T AT95931442 T AT 95931442T AT 95931442 T AT95931442 T AT 95931442T AT E176784 T1 ATE176784 T1 AT E176784T1
Authority
AT
Austria
Prior art keywords
biphenylmethylthiadiazoline
producing
derivatives
salts
compounds required
Prior art date
Application number
AT95931442T
Other languages
English (en)
Inventor
Satoshi Inoue
Nobuya Sakae
Masaharu Yokomoto
Kouji Nishimura
Terukage Hirata
Original Assignee
Wakunaga Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wakunaga Seiyaku Kk filed Critical Wakunaga Seiyaku Kk
Application granted granted Critical
Publication of ATE176784T1 publication Critical patent/ATE176784T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT95931442T 1994-09-20 1995-09-19 Verfahren zur herstellung von n- biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen ATE176784T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22443994 1994-09-20
JP31813194 1994-12-21

Publications (1)

Publication Number Publication Date
ATE176784T1 true ATE176784T1 (de) 1999-03-15

Family

ID=26526062

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95931442T ATE176784T1 (de) 1994-09-20 1995-09-19 Verfahren zur herstellung von n- biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen

Country Status (8)

Country Link
US (1) US5965738A (de)
EP (1) EP0782996B1 (de)
AT (1) ATE176784T1 (de)
DE (1) DE69507887T2 (de)
DK (1) DK0782996T3 (de)
ES (1) ES2129850T3 (de)
GR (1) GR3029836T3 (de)
WO (1) WO1996009301A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1140450A (zh) * 1994-02-10 1997-01-15 湧永制药株式会社 联苯甲烷衍生物的钾盐和含它们的药物
KR19990022836A (ko) * 1995-06-27 1999-03-25 기스케 와구나가, 구사이 요시히로 테트라졸릴화 비페닐메탄 유도체의 제조방법
GB0222056D0 (en) * 2002-09-23 2002-10-30 Novartis Ag Process for the manufacture of organic compounds
PT1509517E (pt) * 2003-01-16 2008-08-05 Teva Pharma Nova síntese de irbesartan
WO2004091438A2 (en) * 2003-04-15 2004-10-28 Fxs Ventures, Llc Improved ophthalmic and contact lens solutions containing peptides as representative enhancers
EP1660463B1 (de) * 2003-08-08 2007-12-05 Dipharma Francis S.r.l. Verfahren zur herstellung von phenyltetrazolderivaten
ES2251292B1 (es) 2004-04-20 2007-07-01 Inke, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de sus intermedios de sintesis.
ITMI20051989A1 (it) * 2005-10-20 2007-04-21 Dipharma Spa Procedimerntyo per la preparazione di composti antagonisti di angiotensina ii
WO2008027385A2 (en) * 2006-08-29 2008-03-06 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of 5-phenyl -1 trityl-1h-tetrazole

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
US5039814A (en) * 1990-05-02 1991-08-13 Merck & Co., Inc. Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes
US5290780A (en) * 1991-01-30 1994-03-01 American Cyanamid Co. Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
US5206235A (en) * 1991-03-20 1993-04-27 Merck & Co., Inc. Benzo-fused lactams that promote the release of growth hormone
TW226375B (de) * 1991-10-24 1994-07-11 American Home Prod
ATE395341T1 (de) * 1991-11-18 2008-05-15 Du Pont 2-(2'-triphenylmethyl-2'h-tetrazol-5'- yl)phenylborsäure als zwischenprodukt zur synthese von a ii receptorenantagonisten
FR2688781B1 (fr) * 1992-03-23 1994-07-01 Sanofi Elf Imidazolines n-substituees par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant.
DE4218157A1 (de) * 1992-06-02 1993-12-09 Bayer Ag Thiadiazoline
US5310929A (en) * 1992-08-06 1994-05-10 E. I. Du Pont De Nemours And Company Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
WO1994004516A1 (fr) * 1992-08-11 1994-03-03 Wakunaga Seiyaku Kabushiki Kaisha Derive de biphenylmethane et medicament le contenant
US5654322A (en) * 1992-08-11 1997-08-05 Wakunaga Seiyaku Kabushiki Kaisha Biphenylmethane derivatives and pharmaceuticals containing the same
US5317017A (en) * 1992-09-30 1994-05-31 Merck & Co., Inc. N-biphenyl-3-amido substituted benzolactams stimulate growth hormone release
CA2179067A1 (en) * 1993-12-23 1995-06-29 Gordon Creston Campbell, Jr. Polymorphs of losartan and the process for the preparation of form ii of losartan
CN1140450A (zh) * 1994-02-10 1997-01-15 湧永制药株式会社 联苯甲烷衍生物的钾盐和含它们的药物

Also Published As

Publication number Publication date
DK0782996T3 (da) 1999-09-20
WO1996009301A1 (en) 1996-03-28
EP0782996A4 (de) 1997-11-05
EP0782996A1 (de) 1997-07-09
EP0782996B1 (de) 1999-02-17
DE69507887T2 (de) 1999-06-17
DE69507887D1 (de) 1999-03-25
ES2129850T3 (es) 1999-06-16
US5965738A (en) 1999-10-12
GR3029836T3 (en) 1999-06-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee