ATE177208T1 - Nichttrennender chemilumineszenzassay durch spezifische bindung - Google Patents

Nichttrennender chemilumineszenzassay durch spezifische bindung

Info

Publication number
ATE177208T1
ATE177208T1 AT96917616T AT96917616T ATE177208T1 AT E177208 T1 ATE177208 T1 AT E177208T1 AT 96917616 T AT96917616 T AT 96917616T AT 96917616 T AT96917616 T AT 96917616T AT E177208 T1 ATE177208 T1 AT E177208T1
Authority
AT
Austria
Prior art keywords
solid phase
tracer
specific binding
analyte
bound
Prior art date
Application number
AT96917616T
Other languages
English (en)
Inventor
Eve H Barlow
Eddie Carroll Iii
Joseph E Connolly
Michael J Lee
Richard A Martinelli
John T Unger
Original Assignee
Chiron Diagnostics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Diagnostics Corp filed Critical Chiron Diagnostics Corp
Application granted granted Critical
Publication of ATE177208T1 publication Critical patent/ATE177208T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Luminescent Compositions (AREA)
AT96917616T 1995-06-29 1996-06-27 Nichttrennender chemilumineszenzassay durch spezifische bindung ATE177208T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/496,549 US5783453A (en) 1995-06-29 1995-06-29 Non-separation specific binding chemiluminescent assay

Publications (1)

Publication Number Publication Date
ATE177208T1 true ATE177208T1 (de) 1999-03-15

Family

ID=23973125

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96917616T ATE177208T1 (de) 1995-06-29 1996-06-27 Nichttrennender chemilumineszenzassay durch spezifische bindung

Country Status (11)

Country Link
US (1) US5783453A (de)
EP (1) EP0835451B1 (de)
JP (1) JPH11508682A (de)
KR (1) KR19990028561A (de)
AT (1) ATE177208T1 (de)
AU (1) AU700057B2 (de)
BR (1) BR9609390A (de)
CA (1) CA2224825A1 (de)
DE (1) DE69601637T2 (de)
PL (1) PL324312A1 (de)
WO (1) WO1997001763A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087088A (en) * 1997-01-31 2000-07-11 Bayer Corporation Binding assays using more than one label for determining analyte in the presence of interfering factors
US6146836A (en) * 1997-05-19 2000-11-14 Bayer Corporation Immunoassays using anti-allotypic monoclonal antibodies
US6056923A (en) * 1997-06-25 2000-05-02 Clmp, Inc. Dual injector for chemiluminescence immunoanalyzing system
AU5473999A (en) * 1998-08-11 2000-03-06 Bayer Corporation Near infrared chemiluminescent acridinium compounds and uses thereof
GB2359625B (en) * 1999-12-10 2004-10-20 Molecular Light Tech Res Ltd Monitoring oligonucleotide binding process using chemiluminescence quenching
AU2001293232A1 (en) * 2000-08-29 2002-03-13 The Rockefeller University Methods employing fluorescence quenching by metal surfaces
US6723851B2 (en) 2001-10-31 2004-04-20 Quest Diagnostics Investment Incorporated Chemiluminescent compounds and use thereof
US20090196852A1 (en) * 2008-02-04 2009-08-06 Watkinson D Tobin Compositions and methods for diagnosing and treating immune disorders
EP2274613B1 (de) * 2008-04-02 2014-06-04 Abbott Point Of Care, Inc. Verfahren für serologische agglutinierungsverfahren welche in einer dünnfilm-flüssigkeitsprobe durchgeführt werden
CN107478824A (zh) * 2017-08-11 2017-12-15 太原瑞盛生物科技有限公司 一种莱克多巴胺的磁微粒化学发光检测试剂盒及制备方法
CN107478827A (zh) * 2017-08-23 2017-12-15 太原瑞盛生物科技有限公司 一种伏马毒素的化学发光检测试剂盒及其制备方法
CN107356746A (zh) * 2017-08-23 2017-11-17 太原瑞盛生物科技有限公司 一种特布他林的磁微粒化学发光检测试剂盒及制备方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3352791A (en) * 1965-01-22 1967-11-14 American Cyanamid Co Generation of light by the reaction of peroxide with heterocyclic derivatives
US3689391A (en) * 1970-05-13 1972-09-05 Synvar Ass Method for chemically initiating photochemical reactions
US4277437A (en) * 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4576912A (en) * 1978-11-30 1986-03-18 Technicon Instruments Corporation Fluoroimmunoassaying
IL64574A (en) * 1981-04-27 1986-01-31 Syva Co Method for determining the presence of an analyte by determination of the amount of fluorescence in competitive protein binding assays
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
EP0103469B1 (de) * 1982-09-10 1989-02-08 The Welsh National School of Medicine Immunologisches Verfahren zur Bestimmung von Stoffen
DE3310337A1 (de) * 1983-03-22 1984-09-27 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur durchfuehrung von hybridisierungsreaktionen
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4672040A (en) * 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
US4695392A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4698302A (en) * 1983-05-12 1987-10-06 Advanced Magnetics, Inc. Enzymatic reactions using magnetic particles
US4695393A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4628037A (en) * 1983-05-12 1986-12-09 Advanced Magnetics, Inc. Binding assays employing magnetic particles
JPS61217766A (ja) * 1985-03-23 1986-09-27 Tadashi Hara 蛋白質の定量方法および定量装置
US5017473A (en) * 1987-05-26 1991-05-21 Becton, Dickinson And Company Homogeneous chemiluminescence immunoassay using a light absorbing material
US4927769A (en) * 1987-07-08 1990-05-22 Ciba Corning Diagnostics Corp. Method for enhancement of chemiluminescence
JP3787352B2 (ja) * 1987-09-21 2006-06-21 ジェン−プローブ・インコーポレイテッド ハイブリダイゼーション保護検定
PT88665B (pt) * 1987-10-05 1992-12-31 Ml Tecnology Ventures Lp Metodo para a marcacao com ester de acridinio e purificacao de sondas nucleotidicas
US5321136A (en) * 1987-12-31 1994-06-14 London Diagnostics, Inc. Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom
US5241070A (en) * 1988-09-26 1993-08-31 Ciba Corning Diagnostics Corp. Nucleophilic polysubstituted aryl acridinium esters and uses thereof
US5093270A (en) * 1989-05-24 1992-03-03 Ciba Corning Diagnostics Corp. Method for enhancing signal release from liposomes using water-miscible alcohols
CA2028012A1 (en) * 1989-10-23 1991-04-24 Randall Dimond Hybridization assay for campylobacter rrna
DE69125992T2 (de) * 1990-09-14 1997-08-21 Tosoh Corp Verfahren und Kit für Immunoassay
CA2046713A1 (en) * 1990-10-16 1992-04-17 Richard M. Martinelli Amplification of midivariant dna templates
CA2069145C (en) * 1991-05-22 2007-07-31 Edwin F. Ullman Assay method utilizing induced luminescence
EP0854194A3 (de) * 1991-07-10 1998-08-05 Igen, Inc. Verfahren und vorrichtung für verbesserte lumineszenztests unter verwendung von partikel- und chemilumineszenzdetektion
US5395752A (en) * 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays

Also Published As

Publication number Publication date
DE69601637T2 (de) 1999-09-16
DE69601637D1 (de) 1999-04-08
US5783453A (en) 1998-07-21
MX9710410A (es) 1998-07-31
CA2224825A1 (en) 1997-01-16
EP0835451A1 (de) 1998-04-15
JPH11508682A (ja) 1999-07-27
PL324312A1 (en) 1998-05-25
AU6013396A (en) 1997-01-30
BR9609390A (pt) 1999-05-18
KR19990028561A (ko) 1999-04-15
AU700057B2 (en) 1998-12-17
WO1997001763A1 (en) 1997-01-16
EP0835451B1 (de) 1999-03-03

Similar Documents

Publication Publication Date Title
ES2171676T3 (es) Inmunoensayos por quimioluminiscencia para la deteccion de anticuerpos.
ATE177208T1 (de) Nichttrennender chemilumineszenzassay durch spezifische bindung
EP2186910A3 (de) Verfahren und Zusammensetzungen für verbesserte Lumineszenztests unter Verwendung von Mikropartikeln
ATE22730T1 (de) Chromatographisches enzym-immunoverfahren.
ATE241017T1 (de) Nukleinsäure - sandwichassay in lösungsphase mit reduzierten hintergrundsignalen
DE3485920D1 (de) Kolorimetrisches immunoessay auf fester oberflaeche, sowie dazu zu verwendender teststab und seine herstellung.
ATE86670T1 (de) Verwendung von oxidase-enzymsystemen in chemilumineszierenden tests.
ES2022166B3 (es) Ensayo de enlace especifico heterogeneo que emplea un reactivo enlazante agregable.
KR920004839A (ko) 1종 이상의 분석물을 검출하기 위한 동시 검정법
ATE405832T1 (de) Verfahren zur erhöhung des dynamischen messbereichs von auf spezifischen bindereaktionen basierenden, insbesondere immunologischen testelementen
KR890702039A (ko) 1,25-디하이드록시 비타민 d의 분석 방법
PT1040353E (pt) Metodo de despistagem de um analito e estojo
ATE240522T1 (de) Chemilumineszenz-immunoassay zum nachweis eines mit der chagas-erkränkung verbundenen analyts in einer probe
ES2023868B3 (es) Procedimiento de determinacion inmunometrico
DE60222091D1 (de) Dendritische chemilumineszierende Substrate
KR930702680A (ko) 증폭된 불균질 화학발광 면역 검정법
DK1021719T3 (da) Fremgangsmåde til påvisning af antistoffer i en pröve
ES2054686T3 (es) Equipo de inmunoensayo.
DE59610859D1 (de) Immunologische Bestimmungsmethode
DK0967485T3 (da) Specifikke bindingsassays under anvendelse af methylorange
ATE218542T1 (de) Immuntestsystem zur bestimmung von vitamin d
ES2169211T3 (es) Ensayos de proteccion de micelas.
ES2190051T3 (es) Procedimiento de calibrado de un sistema de dosificacion de ligando-antiligando.
ES2078264T3 (es) Reactivos standard para la cuantificacion de vih p24.
SE9303272D0 (sv) Improvement in immunoassays

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties