ATE177641T1 - Zubereitungen von hyaluronsaeure mit niedrigem molekulargewicht zur foerderung der knochenbildung - Google Patents

Zubereitungen von hyaluronsaeure mit niedrigem molekulargewicht zur foerderung der knochenbildung

Info

Publication number: ATE177641T1
Authority: AT; Austria
Prior art keywords: hyaluronic acid; pct; molecular weight; low molecular; bone formation
Prior art date: 1992-04-17

Application number

AT93911478T

Other languages

English (en)

Inventor

Lanfranco Callegaro

Aurelio Romeo

Original Assignee

Fidia Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-17

Filing date

1993-04-16

Publication date

1999-04-15

1993-04-16 Application filed by Fidia Spa filed Critical Fidia Spa

1999-04-15 Application granted granted Critical

1999-04-15 Publication of ATE177641T1 publication Critical patent/ATE177641T1/de

Links

KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 4
229920002674 hyaluronan Polymers 0.000 title abstract 4
229960003160 hyaluronic acid Drugs 0.000 title abstract 4
230000011164 ossification Effects 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
230000001737 promoting effect Effects 0.000 title 1
239000000061 acid fraction Substances 0.000 abstract 3
239000008194 pharmaceutical composition Substances 0.000 abstract 2
208000020084 Bone disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000002138 osteoinductive effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Polymers & Plastics (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Physical Education & Sports Medicine (AREA)
Materials Engineering (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Materials For Medical Uses (AREA)

AT93911478T 1992-04-17 1993-04-16 Zubereitungen von hyaluronsaeure mit niedrigem molekulargewicht zur foerderung der knochenbildung ATE177641T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITPD920071A IT1260148B (it)	1992-04-17	1992-04-17	Impiego di preparazioni di acido ialuronico per la formazione di tessuto osseo

Publications (1)

Publication Number	Publication Date
ATE177641T1 true ATE177641T1 (de)	1999-04-15

Family

ID=11389901

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93911478T ATE177641T1 (de)	1992-04-17	1993-04-16	Zubereitungen von hyaluronsaeure mit niedrigem molekulargewicht zur foerderung der knochenbildung

Country Status (11)

Country	Link
US (1)	US5646129A (de)
EP (1)	EP0637245B1 (de)
JP (1)	JP3333205B2 (de)
KR (1)	KR100310277B1 (de)
AT (1)	ATE177641T1 (de)
AU (1)	AU677189B2 (de)
CA (1)	CA2118219C (de)
DE (1)	DE69324006T2 (de)
ES (1)	ES2130268T3 (de)
IT (1)	IT1260148B (de)
WO (1)	WO1993020827A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995001181A1 (en) *	1993-07-01	1995-01-12	Allelix Biopharmaceuticals Inc.	Hyaluronic acid fragments and their therapeutic use
IT1282219B1 (it) *	1995-12-20	1998-03-16	Fidia Advanced Biopolymers Srl	Processo chimico fisico combinato per la preparazione di frazioni di acido ialuronico a basso peso molecolare caratterizzate da bassa
US6875753B1 (en)	1996-03-14	2005-04-05	The Governors Of The University Of Alberta	Methods for cell mobilization using in vivo treatment with hyaluronan (HA)
US20050101564A1 (en) *	1996-04-02	2005-05-12	Pilarski Linda M.	Methods for cell mobilization using in vivo treatment with hyaluronan (HA)
US5939047A (en) *	1996-04-16	1999-08-17	Jernberg; Gary R.	Local delivery of chemotherapeutic agents for treatment of periodontal disease
US6872819B1 (en)	1998-05-27	2005-03-29	Fidia Advanced Biopolymers S.R.L.	Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells
JP3032824B1 (ja) *	1999-01-28	2000-04-17	東京医科歯科大学長	骨誘導促進剤
AU770196B2 (en) *	1999-02-04	2004-02-12	Warsaw Orthopedic, Inc.	Osteogenic paste compositions and uses thereof
IT1306644B1 (it)	1999-04-08	2001-10-02	Fidia Advanced Biopolymers Srl	Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico.
US6576226B1 (en)	2000-11-17	2003-06-10	Gary R. Jernberg	Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6726898B2 (en)	2000-11-17	2004-04-27	Gary R. Jernberg	Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
JP2004250592A (ja) *	2003-02-20	2004-09-09	Seikagaku Kogyo Co Ltd	紫外線照射による低分子化グリコサミノグリカンの製造方法
US20040180025A1 (en) *	2003-03-12	2004-09-16	New Life Resources, Llc	Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US6946551B2 (en) *	2003-03-12	2005-09-20	New Life Resources, Llc	Preparation of hyaluronic acid from eggshell membrane
US20080063677A1 (en) *	2004-03-10	2008-03-13	New Life Resources, Llc	Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US8580315B2 (en) *	2004-03-10	2013-11-12	Esm Technologies, Llc	Anti-inflammatory activity of eggshell membrane and processed eggshell membrane preparations
US20050226936A1 (en)	2004-04-08	2005-10-13	Q-Med Ab	Method of soft tissue augmentation
US20060183709A1 (en) *	2005-02-15	2006-08-17	Ahmad Alkayali	Preparation of low molecular weight hyaluronic acid as a food supplement
US20100075921A1 (en) *	2005-02-15	2010-03-25	Ahmad Alkayali	Prêparation of hyaluronic acid with desired low molecular weight as a food supplement
US20070099867A1 (en) *	2005-05-24	2007-05-03	Glycoscience Laboratories, Inc.	Pharmaceutical agent containing hyaluronan as an active ingredient
JP2009091248A (ja) *	2006-01-17	2009-04-30	Toshitsu Kagaku Kenkyusho:Kk	外傷性神経障害および／または運動機能障害の治療薬
EP1994934A4 (de)	2006-12-05	2010-03-10	Glycoscience Lab Inc	Therapeutisches mittel gegen degenerative arthritis
US8529951B1 (en)	2007-02-21	2013-09-10	Anand Ramamurthi	Elastogenic cues and methods for using same
FR2919185B1 (fr) *	2007-07-23	2010-09-10	Ard Sa	Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de l'etat des muqueuses
EP2818543B8 (de)	2012-02-21	2018-03-07	Bloomage Freda Biopharm Co., Ltd.	Bacillus, hyaluronsäureenzym und verwendungen davon
IL262180B2 (en) *	2016-04-12	2025-12-01	Illustris Pharmaceuticals Inc	Compositions for topical application of compounds
JP2018168263A (ja) *	2017-03-29	2018-11-01	日油株式会社	植物性プロテオグリカン及びその用途
MY210233A (en) *	2017-10-11	2025-09-04	Illustris Pharmaceuticals Inc	Methods and compositions for topical delivery
US20210000910A1 (en)	2019-07-03	2021-01-07	Jysk Skin Solutions Pte Ltd	Topical compositions
US12083204B2 (en)	2022-06-02	2024-09-10	L'oreal	Topical composition for homeostatic delivery of nitric oxide and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2553099B1 (fr) *	1983-10-11	1989-09-08	Fidia Spa	Fractions d'acide hyaluronique ayant une activite pharmaceutique, procedes pour leur preparation et compositions pharmaceutiques les contenant
JP2604135B2 (ja) *	1986-02-28	1997-04-30	ライオン株式会社	口腔骨疾患治療剤
US5041138A (en) *	1986-11-20	1991-08-20	Massachusetts Institute Of Technology	Neomorphogenesis of cartilage in vivo from cell culture
US5079236A (en) *	1987-05-27	1992-01-07	Hyal Pharmaceutical Corporation	Pure, sterile, pyrogen-free hyaluronic acid formulations their methods of preparation and methods of use
GB2215209B (en) *	1988-03-14	1992-08-26	Osmed Inc	Method and apparatus for biodegradable, osteogenic, bone graft substitute device
JPH01265970A (ja) *	1988-04-19	1989-10-24	Shiseido Co Ltd	ヒアルロン酸を含有させたコラーゲン水溶液又は水分散液
US5059123A (en) *	1990-05-14	1991-10-22	Jernberg Gary R	Periodontal barrier and method for aiding periodontal tissue regeneration
SE501217C2 (sv) *	1990-12-06	1994-12-12	Skandigen Ab	Cellproliferationsmatris och användning därav

1992
- 1992-04-17 IT ITPD920071A patent/IT1260148B/it active IP Right Grant
1993
- 1993-04-16 AT AT93911478T patent/ATE177641T1/de active
- 1993-04-16 DE DE69324006T patent/DE69324006T2/de not_active Expired - Lifetime
- 1993-04-16 EP EP93911478A patent/EP0637245B1/de not_active Expired - Lifetime
- 1993-04-16 WO PCT/EP1993/000932 patent/WO1993020827A1/en not_active Ceased
- 1993-04-16 AU AU40404/93A patent/AU677189B2/en not_active Ceased
- 1993-04-16 ES ES93911478T patent/ES2130268T3/es not_active Expired - Lifetime
- 1993-04-16 JP JP51799393A patent/JP3333205B2/ja not_active Expired - Fee Related
- 1993-04-16 US US08/318,804 patent/US5646129A/en not_active Expired - Lifetime
- 1993-04-16 CA CA002118219A patent/CA2118219C/en not_active Expired - Lifetime
1994
- 1994-10-14 KR KR1019940703659A patent/KR100310277B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2118219A1 (en)	1993-10-28
DE69324006D1 (de)	1999-04-22
ITPD920071A0 (it)	1992-04-17
AU4040493A (en)	1993-11-18
WO1993020827A1 (en)	1993-10-28
EP0637245A1 (de)	1995-02-08
ES2130268T3 (es)	1999-07-01
CA2118219C (en)	2004-06-01
KR100310277B1 (ko)	2001-12-28
JP3333205B2 (ja)	2002-10-15
JPH08508973A (ja)	1996-09-24
IT1260148B (it)	1996-03-28
DE69324006T2 (de)	1999-11-11
EP0637245B1 (de)	1999-03-17
AU677189B2 (en)	1997-04-17
US5646129A (en)	1997-07-08
ITPD920071A1 (it)	1993-10-17

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Legal Events

Date	Code	Title	Description
1999-12-15	UEP	Publication of translation of european patent specification
2004-07-15	EEFA	Change of the company name