ATE178065T1 - Kondensierte imidazol- und triazolderivate als 5- hta rezeptoragonisten - Google Patents

Kondensierte imidazol- und triazolderivate als 5- hta rezeptoragonisten

Info

Publication number
ATE178065T1
ATE178065T1 AT93911925T AT93911925T ATE178065T1 AT E178065 T1 ATE178065 T1 AT E178065T1 AT 93911925 T AT93911925 T AT 93911925T AT 93911925 T AT93911925 T AT 93911925T AT E178065 T1 ATE178065 T1 AT E178065T1
Authority
AT
Austria
Prior art keywords
pct
receptor agonists
triazole derivatives
condensed imidazole
date nov
Prior art date
Application number
AT93911925T
Other languages
English (en)
Inventor
Leslie Joseph Spruce Street
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE178065T1 publication Critical patent/ATE178065T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
AT93911925T 1992-05-15 1993-05-06 Kondensierte imidazol- und triazolderivate als 5- hta rezeptoragonisten ATE178065T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929210400A GB9210400D0 (en) 1992-05-15 1992-05-15 Therapeutic agents

Publications (1)

Publication Number Publication Date
ATE178065T1 true ATE178065T1 (de) 1999-04-15

Family

ID=10715527

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93911925T ATE178065T1 (de) 1992-05-15 1993-05-06 Kondensierte imidazol- und triazolderivate als 5- hta rezeptoragonisten

Country Status (10)

Country Link
US (1) US5514682A (de)
EP (1) EP0640085B1 (de)
JP (1) JP3283260B2 (de)
AT (1) ATE178065T1 (de)
AU (1) AU671836B2 (de)
CA (1) CA2134986A1 (de)
DE (1) DE69324140T2 (de)
ES (1) ES2128427T3 (de)
GB (1) GB9210400D0 (de)
WO (1) WO1993023396A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
TW251284B (de) * 1992-11-02 1995-07-11 Pfizer
CN1129933A (zh) * 1993-08-31 1996-08-28 辉瑞大药厂 5-芳基吲哚衍生物
JP2829788B2 (ja) * 1994-02-10 1998-12-02 ファイザー インク． ベンゾジアゼピン受容体部位アゴニスト及びアンタゴニストとしての５−ヘテロアリールインドール誘導体
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
US5484763A (en) * 1995-02-10 1996-01-16 American Cyanamid Company Substituted benzisoxazole and benzisothiazole herbicidal agents
CN1268137A (zh) * 1997-07-03 2000-09-27 杜邦药品公司 治疗神经失调的咪唑并嘧啶和咪唑并吡啶
US6465484B1 (en) * 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
US6162804A (en) * 1997-09-26 2000-12-19 Merck & Co., Inc. Tyrosine kinase inhibitors
US6124463A (en) * 1998-07-02 2000-09-26 Dupont Pharmaceuticals Benzimidazoles as corticotropin release factor antagonists
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
CA2341409A1 (en) * 1998-08-31 2000-03-09 Merck And Co., Inc. Novel angiogenesis inhibitors
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
BR0312176A (pt) 2002-06-21 2005-04-05 Suven Life Sciences Ltd Composto, composição farmaceutica, uso de um composto, método para o tratamento, método para reduzir a morbidez e a mortalidade associadas com o excesso de peso, processo para a preparação de um composto, novo intermediario e processo para a preparação de um novo intermediario
MXPA04012834A (es) 2002-06-21 2005-04-25 Suven Life Sciences Ltd Arilalquil indoles novedosos que tienen afinidad por el receptor de la serotonina, utiles como agentes terapeuticos, proceso para su preparacion y composiciones farmaceuticas que los contienen.
KR100776118B1 (ko) 2002-11-28 2007-11-15 수벤 라이프 사이언시스 리미티드 엔-아릴술포닐-3-아미노알콕시인돌
EP1581492B1 (de) 2002-11-28 2008-07-16 Suven Life Sciences Limited N-arylsulfonyl-2-substituierte indole mit affinität zum serotonin rezeptor, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
AU2003292510B2 (en) 2002-12-18 2009-04-23 Suven Life Sciences Limited Tetracyclic 3-substituted indoles having serotonin receptor affinity
JP4866723B2 (ja) * 2004-02-26 2012-02-01 協和発酵キリン株式会社 好中球性炎症疾患の予防及び／または治療剤
EP3170813B1 (de) 2010-10-06 2018-12-12 GlaxoSmithKline LLC Benzimidazol-derivate als pi3-kinase-hemmer
KR20170140382A (ko) * 2015-04-29 2017-12-20 얀센 파마슈티카 엔.브이. 아자벤즈이미다졸 및 ampa 수용체 조절제로서의 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
PL168919B1 (pl) * 1990-10-15 1996-05-31 Pfizer Sposób wytwarzania nowych pochodnych indolu PL PL PL PL
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
TW251284B (de) * 1992-11-02 1995-07-11 Pfizer

Also Published As

Publication number Publication date
EP0640085B1 (de) 1999-03-24
GB9210400D0 (en) 1992-07-01
AU671836B2 (en) 1996-09-12
DE69324140D1 (de) 1999-04-29
AU4269793A (en) 1993-12-13
ES2128427T3 (es) 1999-05-16
WO1993023396A1 (en) 1993-11-25
EP0640085A1 (de) 1995-03-01
CA2134986A1 (en) 1993-11-25
JPH07506825A (ja) 1995-07-27
US5514682A (en) 1996-05-07
JP3283260B2 (ja) 2002-05-20
DE69324140T2 (de) 1999-10-28

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Legal Events

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