ATE180511T1 - Humanisierter b-b10, ein anti-il-2-rezeptor- antikörper - Google Patents

Humanisierter b-b10, ein anti-il-2-rezeptor- antikörper

Info

Publication number
ATE180511T1
ATE180511T1 AT92924875T AT92924875T ATE180511T1 AT E180511 T1 ATE180511 T1 AT E180511T1 AT 92924875 T AT92924875 T AT 92924875T AT 92924875 T AT92924875 T AT 92924875T AT E180511 T1 ATE180511 T1 AT E180511T1
Authority
AT
Austria
Prior art keywords
pct
antibody
date
humanized
receptor
Prior art date
Application number
AT92924875T
Other languages
English (en)
Inventor
Tomoyuki Nakatani
Hideyuki Gomi
John Wijdenes
Hiroshi Noguchi
Original Assignee
Sumitomo Pharma
Biotest Pharma Gmbh
Diaclone
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharma, Biotest Pharma Gmbh, Diaclone filed Critical Sumitomo Pharma
Application granted granted Critical
Publication of ATE180511T1 publication Critical patent/ATE180511T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/461Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464Igs containing CDR-residues from one specie grafted between FR-residues from another
    • C07K16/465Igs containing CDR-residues from one specie grafted between FR-residues from another with additional modified FR-residues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT92924875T 1991-12-06 1992-12-03 Humanisierter b-b10, ein anti-il-2-rezeptor- antikörper ATE180511T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3323319A JPH05244982A (ja) 1991-12-06 1991-12-06 擬人化b−b10

Publications (1)

Publication Number Publication Date
ATE180511T1 true ATE180511T1 (de) 1999-06-15

Family

ID=18153467

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92924875T ATE180511T1 (de) 1991-12-06 1992-12-03 Humanisierter b-b10, ein anti-il-2-rezeptor- antikörper

Country Status (6)

Country Link
US (1) US5886152A (de)
EP (1) EP0616641B1 (de)
JP (1) JPH05244982A (de)
AT (1) ATE180511T1 (de)
DE (1) DE69229278T2 (de)
WO (1) WO1993011238A1 (de)

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WO1993011238A1 (en) 1993-06-10
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