ATE180766T1 - Diester von carbonsäure mit antiviraler und anti- entzündungsaktivität - Google Patents
Diester von carbonsäure mit antiviraler und anti- entzündungsaktivitätInfo
- Publication number
- ATE180766T1 ATE180766T1 AT95910509T AT95910509T ATE180766T1 AT E180766 T1 ATE180766 T1 AT E180766T1 AT 95910509 T AT95910509 T AT 95910509T AT 95910509 T AT95910509 T AT 95910509T AT E180766 T1 ATE180766 T1 AT E180766T1
- Authority
- AT
- Austria
- Prior art keywords
- antiviral
- diester
- carboxylic acid
- inflammatory activity
- inti
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 title 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000005690 diesters Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/16—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by an inorganic acid or a derivative thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C219/22—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/24—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/32—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and esterified hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI940349A IT1274021B (it) | 1994-02-28 | 1994-02-28 | Diesteri dell'acido carbonico ad attivita' antivirale ed antinfiammatoria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE180766T1 true ATE180766T1 (de) | 1999-06-15 |
Family
ID=11367992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95910509T ATE180766T1 (de) | 1994-02-28 | 1995-02-22 | Diester von carbonsäure mit antiviraler und anti- entzündungsaktivität |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5827881A (de) |
| EP (1) | EP0748310B1 (de) |
| JP (1) | JPH09511497A (de) |
| CN (1) | CN1142222A (de) |
| AT (1) | ATE180766T1 (de) |
| AU (1) | AU1758895A (de) |
| CA (1) | CA2184155A1 (de) |
| DE (1) | DE69510043T2 (de) |
| ES (1) | ES2131815T3 (de) |
| FI (1) | FI963316A7 (de) |
| HU (1) | HUT75334A (de) |
| IL (1) | IL112813A0 (de) |
| IT (1) | IT1274021B (de) |
| NO (1) | NO963554L (de) |
| WO (1) | WO1995023128A1 (de) |
| ZA (1) | ZA951612B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4044740B2 (ja) * | 2001-05-31 | 2008-02-06 | 信越化学工業株式会社 | レジスト材料及びパターン形成方法 |
| ES2625547T3 (es) | 2012-09-27 | 2017-07-19 | Bayer Cropscience Ag | Procedimiento de preparación de fenil y piridil pirrolidinas opcionalmente sustituidas |
| CN112876408B (zh) * | 2019-11-29 | 2022-05-17 | 四川大学华西医院 | 一类短效双季铵化合物及其制备方法和用途 |
| CN113087686B (zh) * | 2020-01-08 | 2023-06-09 | 四川大学华西医院 | 一类含氰基的双季铵类化合物及其制备方法和用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE887650C (de) * | 1951-05-03 | 1953-08-24 | Hoechst Ag | Verfahren zur Herstellung basischer Carbonate |
| US2691017A (en) * | 1952-10-25 | 1954-10-05 | Searle & Co | Bis-aminoalkyl carbonate derivatives |
| US3268574A (en) * | 1960-12-28 | 1966-08-23 | Union Carbide Corp | Bis (aminohydrocarbyl) carbonates |
| US3162673A (en) * | 1960-12-28 | 1964-12-22 | Union Carbide Corp | Bis (aminoaliphatic) carbonates and process for preparation |
| US3318942A (en) * | 1963-11-14 | 1967-05-09 | Union Carbide Corp | Stabilized polymerizable carbonate diisocyanate compounds and process for effecting stabilization |
| US3864335A (en) * | 1968-10-18 | 1975-02-04 | Rohm & Haas | Polyfunctional Ester Oxazolidines |
| US3622613A (en) * | 1969-04-25 | 1971-11-23 | Gen Mills Inc | Carbonate esters of hydroxy substituted fatty nitriles |
| DE3347072A1 (de) * | 1983-12-24 | 1985-07-04 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von n-vinylierten ungesaettigten fuenfgliedrigen n-heterocyclen |
| HU208029B (en) * | 1988-06-03 | 1993-07-28 | Italfarmaco Spa | Process for producing glycose-amino-glycane salts and pharmaceutical compositions containing them |
| US5153348A (en) * | 1990-09-14 | 1992-10-06 | Lever Brothers Company, Division Of Conopco, Inc. | Transesterification route to quaternary ammonium substituted carbonate esters |
| US5164497A (en) * | 1990-09-20 | 1992-11-17 | Union Carbide Chemicals & Plastics Technology Corporation | Decarboxylation processes using mixed metal oxide catalysts |
| DE4203908A1 (de) * | 1992-02-11 | 1993-08-12 | Rwe Dea Ag | Diaminocarbonat-verbindungen und deren anwendung als katalysatoren |
-
1994
- 1994-02-28 IT ITMI940349A patent/IT1274021B/it active IP Right Grant
-
1995
- 1995-02-22 AU AU17588/95A patent/AU1758895A/en not_active Abandoned
- 1995-02-22 CN CN95191817A patent/CN1142222A/zh active Pending
- 1995-02-22 CA CA002184155A patent/CA2184155A1/en not_active Abandoned
- 1995-02-22 EP EP95910509A patent/EP0748310B1/de not_active Expired - Lifetime
- 1995-02-22 DE DE69510043T patent/DE69510043T2/de not_active Expired - Fee Related
- 1995-02-22 JP JP7522122A patent/JPH09511497A/ja not_active Ceased
- 1995-02-22 WO PCT/EP1995/000637 patent/WO1995023128A1/en not_active Ceased
- 1995-02-22 FI FI963316A patent/FI963316A7/fi not_active Application Discontinuation
- 1995-02-22 AT AT95910509T patent/ATE180766T1/de not_active IP Right Cessation
- 1995-02-22 ES ES95910509T patent/ES2131815T3/es not_active Expired - Lifetime
- 1995-02-22 HU HU9602345A patent/HUT75334A/hu unknown
- 1995-02-27 ZA ZA951612A patent/ZA951612B/xx unknown
- 1995-02-27 IL IL11281395A patent/IL112813A0/xx unknown
-
1996
- 1996-08-26 NO NO963554A patent/NO963554L/no unknown
-
1997
- 1997-06-04 US US08/869,043 patent/US5827881A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI940349A1 (it) | 1995-09-01 |
| EP0748310B1 (de) | 1999-06-02 |
| HU9602345D0 (en) | 1996-10-28 |
| ITMI940349A0 (it) | 1994-02-28 |
| JPH09511497A (ja) | 1997-11-18 |
| IT1274021B (it) | 1997-07-14 |
| ES2131815T3 (es) | 1999-08-01 |
| AU1758895A (en) | 1995-09-11 |
| FI963316L (fi) | 1996-10-17 |
| EP0748310A1 (de) | 1996-12-18 |
| CA2184155A1 (en) | 1995-08-31 |
| IL112813A0 (en) | 1995-05-26 |
| NO963554L (no) | 1996-08-26 |
| FI963316A0 (fi) | 1996-08-26 |
| HUT75334A (en) | 1997-05-28 |
| CN1142222A (zh) | 1997-02-05 |
| US5827881A (en) | 1998-10-27 |
| FI963316A7 (fi) | 1996-10-17 |
| ZA951612B (en) | 1995-12-07 |
| DE69510043T2 (de) | 1999-09-23 |
| WO1995023128A1 (en) | 1995-08-31 |
| DE69510043D1 (de) | 1999-07-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |