ATE182080T1 - Dosierungsform die ein antigen und eine salzform eines organischen säurederivats eines sterols enthält - Google Patents

Dosierungsform die ein antigen und eine salzform eines organischen säurederivats eines sterols enthält

Info

Publication number
ATE182080T1
ATE182080T1 AT94201844T AT94201844T ATE182080T1 AT E182080 T1 ATE182080 T1 AT E182080T1 AT 94201844 T AT94201844 T AT 94201844T AT 94201844 T AT94201844 T AT 94201844T AT E182080 T1 ATE182080 T1 AT E182080T1
Authority
AT
Austria
Prior art keywords
antigen
sterol
organic acid
acid derivative
dosage form
Prior art date
Application number
AT94201844T
Other languages
English (en)
Inventor
Mircea C Popescu
Marie S Recine
Carl L Alving
Leonard F Estis
Lynn D Keyes
Andrew S Janoff
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of ATE182080T1 publication Critical patent/ATE182080T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT94201844T 1988-08-25 1989-08-25 Dosierungsform die ein antigen und eine salzform eines organischen säurederivats eines sterols enthält ATE182080T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23670188A 1988-08-25 1988-08-25
US23670288A 1988-08-25 1988-08-25
US39777789A 1989-08-23 1989-08-23

Publications (1)

Publication Number Publication Date
ATE182080T1 true ATE182080T1 (de) 1999-07-15

Family

ID=27398905

Family Applications (2)

Application Number Title Priority Date Filing Date
AT94201844T ATE182080T1 (de) 1988-08-25 1989-08-25 Dosierungsform die ein antigen und eine salzform eines organischen säurederivats eines sterols enthält
AT89402343T ATE119037T1 (de) 1988-08-25 1989-08-25 Influenzaimpfstoff und adjuvanten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT89402343T ATE119037T1 (de) 1988-08-25 1989-08-25 Influenzaimpfstoff und adjuvanten.

Country Status (9)

Country Link
EP (2) EP0356339B1 (de)
JP (1) JPH04500203A (de)
AT (2) ATE182080T1 (de)
AU (2) AU631377B2 (de)
CA (1) CA1337332C (de)
DE (2) DE68921389T2 (de)
ES (2) ES2133477T3 (de)
GR (1) GR3031244T3 (de)
NZ (2) NZ241926A (de)

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Publication number Publication date
EP0626169B1 (de) 1999-07-14
GR3031244T3 (en) 1999-12-31
DE68921389D1 (de) 1995-04-06
ES2133477T3 (es) 1999-09-16
JPH04500203A (ja) 1992-01-16
EP0356339A1 (de) 1990-02-28
EP0626169A2 (de) 1994-11-30
ATE119037T1 (de) 1995-03-15
AU631377B2 (en) 1992-11-26
DE68921389T2 (de) 1995-06-29
DE68929033T2 (de) 1999-12-30
AU4186189A (en) 1990-03-23
CA1337332C (en) 1995-10-17
EP0626169A3 (de) 1995-12-13
AU4221489A (en) 1990-03-23
EP0356339B1 (de) 1995-03-01
AU627226B2 (en) 1992-08-20
NZ230423A (en) 1993-08-26
DE68929033D1 (de) 1999-08-19
NZ241926A (en) 1993-08-26
ES2069600T3 (es) 1995-05-16

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