ATE183198T1 - Immunogens gegen gonadotropin releasing hormone - Google Patents
Immunogens gegen gonadotropin releasing hormoneInfo
- Publication number
- ATE183198T1 ATE183198T1 AT95909395T AT95909395T ATE183198T1 AT E183198 T1 ATE183198 T1 AT E183198T1 AT 95909395 T AT95909395 T AT 95909395T AT 95909395 T AT95909395 T AT 95909395T AT E183198 T1 ATE183198 T1 AT E183198T1
- Authority
- AT
- Austria
- Prior art keywords
- gonadotropin releasing
- releasing hormones
- immunogen against
- against gonadotropin
- immunogenic compositions
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title abstract 3
- 229940035638 gonadotropin-releasing hormone Drugs 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- NMJREATYWWNIKX-UHFFFAOYSA-N GnRH Chemical compound C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CC(C)C)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 NMJREATYWWNIKX-UHFFFAOYSA-N 0.000 abstract 1
- 102000006771 Gonadotropins Human genes 0.000 abstract 1
- 108010086677 Gonadotropins Proteins 0.000 abstract 1
- 101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003163 gonadal steroid hormone Substances 0.000 abstract 1
- 239000002622 gonadotropin Substances 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
- Y10S530/852—Sperm
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
- Y10S530/852—Sperm
- Y10S530/853—Ovary; eggs; embryos
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/854—Glands
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/11—Gonadotropin; related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Gynecology & Obstetrics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/188,223 US5688506A (en) | 1994-01-27 | 1994-01-27 | Immunogens against gonadotropin releasing hormone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE183198T1 true ATE183198T1 (de) | 1999-08-15 |
Family
ID=22692254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95909395T ATE183198T1 (de) | 1994-01-27 | 1995-01-26 | Immunogens gegen gonadotropin releasing hormone |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US5688506A (de) |
| EP (1) | EP0741744B1 (de) |
| JP (1) | JP3477713B2 (de) |
| AT (1) | ATE183198T1 (de) |
| AU (1) | AU698738B2 (de) |
| DE (1) | DE69511379T2 (de) |
| DK (1) | DK0741744T3 (de) |
| ES (1) | ES2137498T3 (de) |
| GR (1) | GR3031716T3 (de) |
| WO (1) | WO1995020600A1 (de) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6030617A (en) * | 1993-01-12 | 2000-02-29 | The Johns Hopkins University School Of Medicine | Use of growth differentiation factor-9 (GDF-9) to inhibit oocyte maturation |
| US5688506A (en) * | 1994-01-27 | 1997-11-18 | Aphton Corp. | Immunogens against gonadotropin releasing hormone |
| GB9514816D0 (en) | 1995-07-19 | 1995-09-20 | Ucli Ltd | Substances and their medical use |
| DE69740173D1 (de) * | 1996-02-08 | 2011-05-26 | Cancer Advances Inc | Immunologische methoden zur behandlung von gastrointestinalem krebs |
| DE69827621T9 (de) * | 1997-05-12 | 2007-06-06 | Aphton Corp., Woodland | Immunogene zusammensetzungen gegen den cck-b-gastrin-rezeptor und verfahren zur behandlung von tumoren |
| US20040001842A1 (en) * | 1997-05-12 | 2004-01-01 | Dov Michaeli | Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors |
| AUPO776897A0 (en) * | 1997-07-09 | 1997-07-31 | Csl Limited | A method of achieving production gains in livestock and agents useful for same |
| PT1077721E (pt) * | 1998-05-15 | 2007-06-21 | Receptor Biologix Inc | Prevenção e tratamento da hipergastrinemia. |
| US20030068326A1 (en) * | 1998-05-15 | 2003-04-10 | Aphton Corporation | Method for the treatment of gastroesophageal reflux disease |
| AUPP807399A0 (en) | 1999-01-08 | 1999-02-04 | Csl Limited | Improved immunogenic lhrh composition and methods relating thereto |
| GB9924351D0 (en) * | 1999-10-14 | 1999-12-15 | Brennan Frank | Immunomodulation methods and compositions |
| EP1246645A2 (de) * | 1999-12-23 | 2002-10-09 | Aphton Corporation | Stabile immunogenische zusammensetzung zur gefrorene lagerung |
| US6783761B2 (en) | 2000-05-05 | 2004-08-31 | Aphton Corporation | Chimeric peptide immunogens |
| DK2266603T3 (da) | 2000-10-18 | 2012-11-05 | Glaxosmithkline Biolog Sa | Tumorvacciner |
| US20040086903A1 (en) | 2000-12-29 | 2004-05-06 | Jean-Jacques Lareyre | Epididymal lipocalin gene and uses thereof |
| CA2441228A1 (en) | 2001-03-23 | 2002-10-03 | Aphton Corporation | Combination treatment of pancreatic cancer |
| US20090191232A1 (en) | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
| US6810583B2 (en) * | 2001-08-07 | 2004-11-02 | International Business Machines Corporation | Coupling of conductive vias to complex power-signal substructures |
| IL147138A0 (en) * | 2001-12-17 | 2002-08-14 | Yeda Res & Dev | Methods of and pharmaceutical compositions for modulating cell adhesion, migration and extravasation |
| US20040247661A1 (en) * | 2002-07-03 | 2004-12-09 | Dov Michaeli | Liposomal vaccine |
| EP1528915A2 (de) * | 2002-07-03 | 2005-05-11 | Aphton Corporation | Liposomaler impfstoff |
| US20050169979A1 (en) * | 2002-07-03 | 2005-08-04 | Dov Michaeli | Liposomal vaccine |
| CN1781023A (zh) | 2003-03-28 | 2006-05-31 | 埃弗顿有限公司 | 胃泌素激素免疫测定 |
| EP1684782B1 (de) | 2003-10-03 | 2015-09-30 | Thorn BioScience, LLC | Verfahren zur synchronisierung der ovulation für zeitlich angepasstes brüten ohne hitzenachweis |
| WO2005102385A1 (en) | 2004-04-26 | 2005-11-03 | Innate Pharma | Adjuvant composition and methods for its use |
| WO2005120552A1 (en) * | 2004-06-11 | 2005-12-22 | Ym Biosciences Inc. | METHODS AND FORMULATIONS OF GnRH/LEUKOTOXIN CHIMERAS FOR TESTOSTERONE SUPPRESSION |
| JP2008513536A (ja) | 2004-09-22 | 2008-05-01 | レセプター バイオロジックス インコーポレイテッド | プロガストリンに対するモノクローナル抗体 |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| US8278421B2 (en) | 2006-03-20 | 2012-10-02 | Xoma Techolology Ltd. | Human antibodies specific for gastrin materials and methods |
| EP2049524A2 (de) * | 2006-07-24 | 2009-04-22 | Tetralogic Pharmaceuticals Corporation | Iap-hemmer |
| HUE036180T2 (hu) | 2006-09-26 | 2018-06-28 | Infectious Disease Res Inst | Szintetikus adjuvánst tartalmazó vakcina készítmény |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| PT2086582E (pt) | 2006-10-12 | 2013-01-25 | Glaxosmithkline Biolog Sa | Vacina compreendendo uma emulsão adjuvante óleo em água |
| EP2433648A3 (de) | 2006-10-12 | 2012-04-04 | GlaxoSmithKline Biologicals S.A. | Impfstoff mit einem Öl-in-wasser-emulsionshilfsstoff |
| CA2687632C (en) | 2007-05-24 | 2013-01-15 | Glaxosmithkline Biologicals S.A. | Lyophilised antigen composition |
| EP2072060A1 (de) | 2007-12-18 | 2009-06-24 | Institut Curie | Verfahren und Zusammensetzungen zur Herstellung und Verwendung von Toxinkonjugaten |
| JP5559789B2 (ja) * | 2008-08-07 | 2014-07-23 | マーシア・ファーマ・インコーポレイテッド | アルツハイマー病の処置のための免疫治療組成物 |
| CU23739A1 (es) | 2008-09-30 | 2011-12-28 | Ct Ingenieria Genetica Biotech | Composición farmacéutica utilizando combinaciones de variantes de la hormona liberadora de las gonadotropinas (gnrh) como inmunógeno |
| BR122013009981B1 (pt) | 2009-04-23 | 2020-02-11 | United-Ah Ii, Llc | Composição para sincronizar o tempo de inseminação |
| HUE031051T2 (en) | 2009-06-05 | 2017-06-28 | Infectious Disease Res Inst | Synthetic glycopyranosyl lipid adjuvant and vaccine compositions containing it |
| US8283372B2 (en) | 2009-07-02 | 2012-10-09 | Tetralogic Pharmaceuticals Corp. | 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic |
| EP2675473A1 (de) | 2011-02-15 | 2013-12-25 | Immune Design Corp. | Verfahren zur verbesserung von immunogenspezifischen immunreaktionen durch vektorisierte impfstoffe |
| EP3632463A1 (de) | 2011-04-08 | 2020-04-08 | Immune Design Corp. | Immunogene zusammensetzungen und verfahren zur verwendung der zusammensetzungen zur induzierung humoraler und zellulärer immunreaktionen |
| GB201121571D0 (en) | 2011-12-15 | 2012-01-25 | Astrimmune Ltd | Compounds and uses thereof |
| WO2013119856A1 (en) | 2012-02-07 | 2013-08-15 | Infectious Disease Research Institute | Improved adjuvant formulations comprising tlr4 agonists and methods of using the same |
| SI2850431T1 (en) | 2012-05-16 | 2018-08-31 | Immune Design Corp. | Vaccines for hsv-2 |
| EP2900275A4 (de) | 2012-09-29 | 2016-05-25 | Univ Pennsylvania | Tierärztliche zusammensetzung und verfahren für nichtoperative kastration |
| BR112015012453A8 (pt) | 2012-11-28 | 2021-06-29 | Jbs United Animal Health Ii Llc | métodos e usos para sincronizar o tempo de ovulação e de inseminação em uma leitoa |
| EP2986303B1 (de) | 2013-04-18 | 2020-02-26 | Immune Design Corp. | Gla-monotherapie zur verwendung in der krebsbehandlung |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| IL246456B2 (en) | 2013-12-31 | 2024-06-01 | Access To Advanced Health Inst | Formulations will be assembled into a single vial |
| US20170196954A1 (en) | 2014-07-15 | 2017-07-13 | Immune Design Corp. | Prime-boost regimens with a tlr4 agonist adjuvant and a lentiviral vector |
| WO2017180420A1 (en) | 2016-04-11 | 2017-10-19 | Board Of Regents, The University Of Texas System | Methods and compositions for detecting single t cell receptor affinity and sequence |
| MX2018014086A (es) | 2016-05-16 | 2019-09-18 | Infectious Disease Res Inst | Formulacion que contiene agonista tlr y metodos de uso. |
| BR112018073676B1 (pt) | 2016-05-16 | 2023-10-03 | University Of Virginia Patent Foundation | Lipossomas peguilados e métodos de uso |
| CA3023271A1 (en) | 2016-06-01 | 2017-12-07 | Infectious Disease Research Institute | Nanoalum particles containing a sizing agent |
| JP7469225B2 (ja) | 2017-06-15 | 2024-04-16 | キャンサー アドヴァンシーズ インク. | 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法 |
| US11141377B2 (en) | 2017-06-15 | 2021-10-12 | Infectious Disease Research Institute | Nanostructured lipid carriers and stable emulsions and uses thereof |
| US12150978B2 (en) | 2017-06-15 | 2024-11-26 | Cancer Advances Inc. | Compositions and methods for preventing tumors and cancer |
| CA3078223A1 (en) | 2017-09-08 | 2019-03-14 | Infectious Disease Research Institute | Liposomal formulations comprising saponin and methods of use |
| WO2020243115A1 (en) | 2019-05-25 | 2020-12-03 | Infectious Disease Research Institute | Composition and method for spray drying an adjuvant vaccine emulsion |
| WO2022051022A1 (en) | 2020-09-04 | 2022-03-10 | Infectious Disease Research Institute | Co-lyophilized rna and nanostructured lipid carrier |
| WO2022051024A1 (en) | 2020-09-04 | 2022-03-10 | Infectious Disease Research Institute | Genetically-adjuvanted rna vaccines |
| CN117120087A (zh) | 2020-12-23 | 2023-11-24 | 高级健康研究所 | 茄尼醇疫苗助剂及其制备方法 |
| EP4583841A1 (de) | 2022-09-09 | 2025-07-16 | Access to Advanced Health Institute | Immunogene impfstoffzusammensetzung mit einem saponin |
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| US4384995A (en) * | 1980-01-16 | 1983-05-24 | The Ohio State University | Antigenic modification of polypeptides |
| US4302386A (en) * | 1978-08-25 | 1981-11-24 | The Ohio State University | Antigenic modification of polypeptides |
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| US4526716A (en) * | 1981-11-20 | 1985-07-02 | The Ohio State University | Antigenic modification of polypeptides |
| US4201770A (en) * | 1973-05-07 | 1980-05-06 | The Ohio State University | Antigenic modification of polypeptides |
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| US4676981A (en) * | 1984-02-07 | 1987-06-30 | University Of Saskatchewan | Monoclonal antibodies against GnRH |
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| AU5359186A (en) * | 1985-01-25 | 1986-08-13 | Population Council, Inc., The | Method & product for enhancing circulating antibody response |
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| CA1239346A (en) * | 1985-06-04 | 1988-07-19 | National Institute Of Immunology | Birth control vaccine |
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-
1994
- 1994-01-27 US US08/188,223 patent/US5688506A/en not_active Expired - Fee Related
-
1995
- 1995-01-26 AU AU17371/95A patent/AU698738B2/en not_active Ceased
- 1995-01-26 AT AT95909395T patent/ATE183198T1/de not_active IP Right Cessation
- 1995-01-26 DK DK95909395T patent/DK0741744T3/da active
- 1995-01-26 JP JP52023395A patent/JP3477713B2/ja not_active Expired - Fee Related
- 1995-01-26 WO PCT/US1995/001225 patent/WO1995020600A1/en not_active Ceased
- 1995-01-26 EP EP95909395A patent/EP0741744B1/de not_active Expired - Lifetime
- 1995-01-26 ES ES95909395T patent/ES2137498T3/es not_active Expired - Lifetime
- 1995-01-26 DE DE69511379T patent/DE69511379T2/de not_active Expired - Fee Related
- 1995-06-07 US US08/478,546 patent/US6303123B1/en not_active Expired - Fee Related
-
1997
- 1997-11-17 US US08/968,466 patent/US6132720A/en not_active Expired - Fee Related
-
1999
- 1999-11-03 GR GR990402808T patent/GR3031716T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5688506A (en) | 1997-11-18 |
| DE69511379D1 (en) | 1999-09-16 |
| DE69511379T2 (de) | 1999-11-25 |
| WO1995020600A1 (en) | 1995-08-03 |
| US6132720A (en) | 2000-10-17 |
| AU698738B2 (en) | 1998-11-05 |
| GR3031716T3 (en) | 2000-02-29 |
| EP0741744A1 (de) | 1996-11-13 |
| US6303123B1 (en) | 2001-10-16 |
| EP0741744B1 (de) | 1999-08-11 |
| JP3477713B2 (ja) | 2003-12-10 |
| DK0741744T3 (da) | 1999-12-06 |
| ES2137498T3 (es) | 1999-12-16 |
| AU1737195A (en) | 1995-08-15 |
| JPH09508391A (ja) | 1997-08-26 |
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Legal Events
| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |