ATE188744T1 - Verfahren zur erhöhung der nachweisempfindlichkeit von nukleinsäure-hybriden (target/probe) - Google Patents

Verfahren zur erhöhung der nachweisempfindlichkeit von nukleinsäure-hybriden (target/probe)

Info

Publication number
ATE188744T1
ATE188744T1 AT95922381T AT95922381T ATE188744T1 AT E188744 T1 ATE188744 T1 AT E188744T1 AT 95922381 T AT95922381 T AT 95922381T AT 95922381 T AT95922381 T AT 95922381T AT E188744 T1 ATE188744 T1 AT E188744T1
Authority
AT
Austria
Prior art keywords
nucleic acid
target
probe
acid sequence
hybridized
Prior art date
Application number
AT95922381T
Other languages
English (en)
Inventor
Sithian Pandian
Eng Jom Aw
David I Smith
Original Assignee
Kalyx Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kalyx Biosciences Inc filed Critical Kalyx Biosciences Inc
Application granted granted Critical
Publication of ATE188744T1 publication Critical patent/ATE188744T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT95922381T 1994-06-28 1995-06-27 Verfahren zur erhöhung der nachweisempfindlichkeit von nukleinsäure-hybriden (target/probe) ATE188744T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2126952A CA2126952C (en) 1994-06-28 1994-06-28 Probe, kit, and method of amplification for increasing the sensitivity of nucleic acid hybridization assays
PCT/CA1995/000369 WO1996000795A2 (en) 1994-06-28 1995-06-27 Method of amplification for increasing the sensitivity of detecting nucleic acid-probe target hybrids

Publications (1)

Publication Number Publication Date
ATE188744T1 true ATE188744T1 (de) 2000-01-15

Family

ID=4153909

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95922381T ATE188744T1 (de) 1994-06-28 1995-06-27 Verfahren zur erhöhung der nachweisempfindlichkeit von nukleinsäure-hybriden (target/probe)

Country Status (8)

Country Link
US (1) US5627030A (de)
EP (1) EP0770142B1 (de)
JP (1) JPH10508741A (de)
AT (1) ATE188744T1 (de)
AU (1) AU2709995A (de)
CA (1) CA2126952C (de)
DE (1) DE69514521D1 (de)
WO (1) WO1996000795A2 (de)

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GB2324370B (en) * 1997-04-14 1999-03-03 Stuart Harbron Detection of hybrid double-stranded DNA with antibody after enzyme degradation of excess single-standed DNA
US6255051B1 (en) 1997-11-06 2001-07-03 Mosaic Technologies Inc. Multiple sequential polynucleotide displacement reactions for signal amplification and processing
BR9814271A (pt) * 1997-12-12 2001-03-20 Digene Corp Determinação de doenças relacionadas com o vìrus do papiloma humano
US6287772B1 (en) * 1998-04-29 2001-09-11 Boston Probes, Inc. Methods, kits and compositions for detecting and quantitating target sequences
US6503747B2 (en) 1998-07-14 2003-01-07 University Of Hawaii Serotype-specific probes for Listeria monocytogenes
WO2000015849A1 (en) * 1998-09-15 2000-03-23 Yale University Artificial long terminal repeat vectors
US6238927B1 (en) 1998-10-05 2001-05-29 Mosaic Technologies, Incorporated Reverse displacement assay for detection of nucleic acid sequences
US6365351B1 (en) * 1999-01-29 2002-04-02 Avi Biopharma, Inc. Non-invasive method for detecting target RNA
WO2004061126A2 (en) * 2002-03-25 2004-07-22 Datascope Investment Corp. Nucleic acid hybridization assay using bridging sequence
US7439016B1 (en) 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
US7601497B2 (en) * 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
US20040029142A1 (en) * 2002-02-11 2004-02-12 Schon Eric A. Concatenation-based nucleic acid detection compositions and methods
US20030198966A1 (en) * 2002-04-19 2003-10-23 Stojanovic Milan N. Displacement assay for detection of small molecules
US7015317B2 (en) * 2002-05-02 2006-03-21 Abbott Laboratories Polynucleotides for the detection and quantification of hepatitis B virus nucleic acids
US7807802B2 (en) 2002-11-12 2010-10-05 Abbott Lab Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US20050019916A1 (en) * 2003-04-14 2005-01-27 Stojanovic Milan N. Cross reactive arrays of three-way junction sensors for steriod determination
US7470516B2 (en) * 2003-04-14 2008-12-30 The Trustees Of Columbia University In The City Of New York Cross reactive arrays of three-way junction sensors for steroid determination
US20040203007A1 (en) * 2003-04-14 2004-10-14 Stojanovic Milan N. Cross reactive arrays of three-way junction sensors for steroid determination
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
CA2653988C (en) 2007-04-13 2017-05-30 Abbott Laboratories Primer and probe sequences for detecting chlamydia trachomatis
TWI417389B (zh) 2008-10-27 2013-12-01 Qiagen Gaithersburg Inc 於自動平台上之快速結果雜交捕捉法
EP2370820B1 (de) * 2008-12-31 2016-02-24 Abbott Point Of Care, Inc. Verfahren und vorrichtung für einen immuntest unter verwendung von nukleotidkonjugaten
EP2385979B1 (de) * 2009-01-28 2017-08-16 QIAGEN Gaithersburg, Inc. Sequenzspezifisches verfahren zur vorbereitung grossvolumiger proben und assay
AU2010242867B2 (en) 2009-05-01 2016-05-12 Qiagen Gaithersburg, Inc. A non-target amplification method for detection of RNA splice-forms in a sample
JP5826752B2 (ja) 2009-09-14 2015-12-02 キアジェン ゲイサーズバーグ インコーポレイテッド 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法
CA2787781A1 (en) 2010-01-29 2011-08-04 Qiagen Gaithersburg, Inc. Method of determining and confirming the presence of an hpv in a sample
ES2615728T3 (es) * 2010-01-29 2017-06-08 Qiagen Gaithersburg, Inc. Métodos y composiciones para una purificación y un análisis múltiple específico de secuencia de ácidos nucleicos
ES2606012T3 (es) * 2010-02-26 2017-03-17 Ventana Medical Systems, Inc. Hibridación in situ con sondas PolyTag
US9422593B2 (en) 2010-05-19 2016-08-23 Qiagen Gaithresburg, Inc Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
ES2657064T3 (es) 2011-01-12 2018-03-01 Abbott Molecular Inc. Materiales y procedimiento para detectar citomegalovirus (CMV)
AU2012220575B2 (en) 2011-02-24 2017-01-12 Qiagen Gaithersburg, Inc. Materials and methods for detection of HPV nucleic acid
US10077474B2 (en) 2012-05-29 2018-09-18 Abbott Molecular, Inc. Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits
CN105229175A (zh) 2013-03-15 2016-01-06 雅培分子公司 用于扩增和测定rna融合基因变体的方法、区分它们的方法以及有关的引物、探针和试剂盒
RU2697502C2 (ru) 2014-07-24 2019-08-14 Эбботт Молекьюлар Инк. Композиции и способы обнаружения и анализа микобактерии туберкулеза (mycobacterium tuberculosis)
EP3322483A4 (de) 2015-07-14 2019-01-02 Abbott Molecular Inc. Zusammensetzungen und verfahren zum nachweis von wirkstoffresistenter tuberkulose
CN114480585B (zh) * 2020-10-28 2024-02-23 清华大学 核酸探针组合物、预处理液、核酸检测试剂盒及检测方法
CN113025690B (zh) * 2021-05-27 2021-08-10 广东品博易视生物科技有限公司 一种核酸探针组及其应用

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US5200313A (en) * 1983-08-05 1993-04-06 Miles Inc. Nucleic acid hybridization assay employing detectable anti-hybrid antibodies
EP0144913A3 (de) * 1983-12-12 1986-08-20 Miles Inc. Hybridisierungstest mittels einer markierten Probe und Anti-Hybrid
EP0146039A3 (de) * 1983-12-12 1986-08-27 Miles Inc. Hybridisierungstest mit Immobilisierung von Hybriden mittels Antihybridbindung
GB8405437D0 (en) * 1984-03-01 1984-04-04 Amersham Int Plc Detecting polynucleotide sequences
DE3420925A1 (de) * 1984-06-05 1985-12-05 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und reagenz zum nachweis einer nukleinsaeure-sequenz
ATE65092T1 (de) * 1985-05-31 1991-07-15 Amoco Corp Verstaerkung von hybridisierungssignalen durch verwendung von komplementarischen dns-straengen.
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
US5175270A (en) * 1986-09-10 1992-12-29 Polyprobe, Inc. Reagents for detecting and assaying nucleic acid sequences
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
CA2039517C (en) * 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
WO1993013226A1 (en) * 1991-12-23 1993-07-08 Chiron Corporation Hav probes for use in solution phase sandwich hybridization assays

Also Published As

Publication number Publication date
WO1996000795A2 (en) 1996-01-11
CA2126952C (en) 2010-12-14
CA2126952A1 (en) 1995-12-29
AU2709995A (en) 1996-01-25
EP0770142A2 (de) 1997-05-02
US5627030A (en) 1997-05-06
JPH10508741A (ja) 1998-09-02
DE69514521D1 (de) 2000-02-17
EP0770142B1 (de) 2000-01-12
WO1996000795A3 (en) 1996-02-22

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