ATE192930T1 - Synthetische oberflächenaktive agentien auf der lunge - Google Patents

Synthetische oberflächenaktive agentien auf der lunge

Info

Publication number: ATE192930T1
Authority: AT; Austria
Prior art keywords: lung surfactant; temperature; composition; phosphatidylcholine; lamellar form
Prior art date: 1990-10-17

Application number

AT91920210T

Other languages

English (en)

Inventor

Andrew S Janoff

Original Assignee

Liposome Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-17

Filing date

1991-10-17

Publication date

2000-06-15

1991-10-17 Application filed by Liposome Co Inc filed Critical Liposome Co Inc

2000-06-15 Application granted granted Critical

2000-06-15 Publication of ATE192930T1 publication Critical patent/ATE192930T1/de

Links

210000004072 lung Anatomy 0.000 title 1
239000004094 surface-active agent Substances 0.000 title 1
239000003580 lung surfactant Substances 0.000 abstract 5
229940066294 lung surfactant Drugs 0.000 abstract 5
WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 3
KILNVBDSWZSGLL-KXQOOQHDSA-N 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC KILNVBDSWZSGLL-KXQOOQHDSA-N 0.000 abstract 2
JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 abstract 2
241000124008 Mammalia Species 0.000 abstract 2
239000000596 artificial lung surfactant Substances 0.000 abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
MWRBNPKJOOWZPW-CLFAGFIQSA-N dioleoyl phosphatidylethanolamine Chemical group CCCCCCCC\C=C/CCCCCCCC(=O)OCC(COP(O)(=O)OCCN)OC(=O)CCCCCCC\C=C/CCCCCCCC MWRBNPKJOOWZPW-CLFAGFIQSA-N 0.000 abstract 2
150000008104 phosphatidylethanolamines Chemical class 0.000 abstract 2
206010001052 Acute respiratory distress syndrome Diseases 0.000 abstract 1
208000013616 Respiratory Distress Syndrome Diseases 0.000 abstract 1
230000036760 body temperature Effects 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
239000000470 constituent Substances 0.000 abstract 1
238000000151 deposition Methods 0.000 abstract 1
150000002632 lipids Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008177 pharmaceutical agent Substances 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
239000002356 single layer Substances 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Plant Substances (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT91920210T 1990-10-17 1991-10-17 Synthetische oberflächenaktive agentien auf der lunge ATE192930T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US59949390A	1990-10-17	1990-10-17
PCT/US1991/007746 WO1992006703A1 (en)	1990-10-17	1991-10-17	Synthetic lung surfactant

Publications (1)

Publication Number	Publication Date
ATE192930T1 true ATE192930T1 (de)	2000-06-15

Family

ID=24399851

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91920210T ATE192930T1 (de)	1990-10-17	1991-10-17	Synthetische oberflächenaktive agentien auf der lunge

Country Status (11)

Country	Link
EP (1)	EP0553272B1 (de)
JP (1)	JP3171445B2 (de)
KR (1)	KR0181309B1 (de)
AT (1)	ATE192930T1 (de)
AU (1)	AU650303B2 (de)
CA (1)	CA2093133C (de)
DE (1)	DE69132211T2 (de)
DK (1)	DK0553272T3 (de)
ES (1)	ES2146580T3 (de)
GR (1)	GR3034211T3 (de)
WO (1)	WO1992006703A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9120005D0 (en) *	1991-09-19	1991-11-06	Wellcome Found	Method of administering phospholipid dispersions
PT877602E (pt)	1996-01-24	2002-07-31	Byk Gulden Lomberg Chem Fab	Processo para o fabrico de composicoes de surfactantes pulmonares em po
US6120795A (en) *	1996-03-27	2000-09-19	Ortho Pharmaceutical Corp.	Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation
AU2003213402A1 (en) *	2002-03-18	2003-09-29	Yamanouchi Pharmaceutical Co., Ltd.	Powdery medicinal compositions for inhalation and process for producing the same
EA201300255A1 (ru)	2010-08-23	2013-06-28	Такеда Гмбх	Увлажненные частицы, содержащие терапевтически активное вещество
AU2015226287B2 (en)	2014-03-05	2019-01-31	Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.	Humidifier for humidifying an aerosol
AU2015226289B8 (en)	2014-03-05	2019-10-31	Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.	Device for providing a constant amount of aerosol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5795920A (en) *	1980-12-04	1982-06-15	Teijin Ltd	Remedy for respiratory disease
US4915951A (en) *	1987-12-03	1990-04-10	California Institute Of Technology	Cryoprotective reagent

1991
- 1991-10-17 DE DE69132211T patent/DE69132211T2/de not_active Expired - Fee Related
- 1991-10-17 WO PCT/US1991/007746 patent/WO1992006703A1/en not_active Ceased
- 1991-10-17 DK DK91920210T patent/DK0553272T3/da active
- 1991-10-17 EP EP91920210A patent/EP0553272B1/de not_active Expired - Lifetime
- 1991-10-17 AU AU89291/91A patent/AU650303B2/en not_active Ceased
- 1991-10-17 AT AT91920210T patent/ATE192930T1/de not_active IP Right Cessation
- 1991-10-17 CA CA002093133A patent/CA2093133C/en not_active Expired - Fee Related
- 1991-10-17 ES ES91920210T patent/ES2146580T3/es not_active Expired - Lifetime
- 1991-10-17 KR KR1019930701000A patent/KR0181309B1/ko not_active Expired - Fee Related
- 1991-10-17 JP JP50075992A patent/JP3171445B2/ja not_active Expired - Fee Related
2000
- 2000-08-17 GR GR20000401896T patent/GR3034211T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU650303B2 (en)	1994-06-16
DK0553272T3 (da)	2000-09-04
EP0553272B1 (de)	2000-05-17
CA2093133A1 (en)	1992-04-18
JPH06502427A (ja)	1994-03-17
EP0553272A1 (de)	1993-08-04
JP3171445B2 (ja)	2001-05-28
DE69132211T2 (de)	2000-11-23
CA2093133C (en)	1999-03-30
GR3034211T3 (en)	2000-12-29
EP0553272A4 (en)	1994-09-07
KR0181309B1 (ko)	1999-03-20
ES2146580T3 (es)	2000-08-16
AU8929191A (en)	1992-05-20
WO1992006703A1 (en)	1992-04-30
DE69132211D1 (de)	2000-06-21

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Legal Events

Date	Code	Title	Description
2000-10-15	UEP	Publication of translation of european patent specification
2006-07-15	REN	Ceased due to non-payment of the annual fee