ATE194610T1 - Derivate des radicicols - Google Patents

Derivate des radicicols

Info

Publication number
ATE194610T1
ATE194610T1 AT96912263T AT96912263T ATE194610T1 AT E194610 T1 ATE194610 T1 AT E194610T1 AT 96912263 T AT96912263 T AT 96912263T AT 96912263 T AT96912263 T AT 96912263T AT E194610 T1 ATE194610 T1 AT E194610T1
Authority
AT
Austria
Prior art keywords
represents hydrogen
alkenoyl
alkanoyl
radicicol
present
Prior art date
Application number
AT96912263T
Other languages
English (en)
Inventor
Tsutomu Agatsuma
Yutaka Saitoh
Yoshinori Yamashita
Tamio Mizukami
Shiro Akinaga
Katsushige Gomi
Kazuhito Akasaka
Isami Takahashi
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE194610T1 publication Critical patent/ATE194610T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Flanged Joints, Insulating Joints, And Other Joints (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT96912263T 1995-04-26 1996-04-26 Derivate des radicicols ATE194610T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10262695 1995-04-26
PCT/JP1996/001158 WO1996033989A1 (en) 1995-04-26 1996-04-26 Radicicol derivatives

Publications (1)

Publication Number Publication Date
ATE194610T1 true ATE194610T1 (de) 2000-07-15

Family

ID=14332458

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96912263T ATE194610T1 (de) 1995-04-26 1996-04-26 Derivate des radicicols

Country Status (13)

Country Link
US (1) US5977165A (de)
EP (1) EP0823429B1 (de)
JP (1) JP3938936B2 (de)
KR (1) KR19990008051A (de)
AT (1) ATE194610T1 (de)
AU (1) AU700840B2 (de)
CA (1) CA2218981C (de)
DE (1) DE69609325T2 (de)
ES (1) ES2149468T3 (de)
HU (1) HUP9901344A3 (de)
NO (1) NO974890L (de)
NZ (1) NZ311790A (de)
WO (1) WO1996033989A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ331062A (en) 1996-10-25 2000-05-26 Kyowa Hakko Kogyo Company Ltd Radicicol derivatives or pharmacologically acceptable salts which show tyrosine kinase inhibition activity and have antitumor effects
JP2001510838A (ja) * 1997-07-25 2001-08-07 アメリカ合衆国 マクロサイクリックラクトン、組成物、および使用方法
WO1999055689A1 (en) * 1998-04-24 1999-11-04 Kyowa Hakko Kogyo Co., Ltd. Radicicol derivatives
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
AU779438B2 (en) 1998-12-24 2005-01-27 Novation Pharmaceuticals Inc. Compounds which affect mRNA stability and uses therefor
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
CN1452619A (zh) 2000-07-26 2003-10-29 史密斯克莱·比奇曼公司 具有抗细菌活性的氨基哌啶喹啉和它们的氮杂等排的类似物
ATE328888T1 (de) * 2000-08-25 2006-06-15 Sloan Kettering Inst Cancer Radicicol und monocillin und ihre analogen und ihre anwendungen
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
US7825094B2 (en) * 2001-05-23 2010-11-02 Sloan-Kettering Institute For Cancer Research Method of treatment for cancers associated with elevated HER 2 levels
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
US20040192638A1 (en) * 2001-07-02 2004-09-30 Oaks John A. Method and composition for prolonging the residence time of drugs in the gut
JP4445753B2 (ja) 2002-01-29 2010-04-07 グラクソ グループ リミテッド アミノピペリジン誘導体
US7109213B2 (en) 2002-01-29 2006-09-19 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
AU2004251949B2 (en) 2003-06-27 2009-05-07 Kyowa Hakko Kirin Co., Ltd. Hsp90 family protein inhibitors
JPWO2005018674A1 (ja) * 2003-08-22 2006-10-19 協和醗酵工業株式会社 イムノグロブリン遺伝子の転座を伴う疾患の治療薬
US20080108694A1 (en) * 2003-12-19 2008-05-08 Samuel J Danishefsky Novel Macrocycles and Uses Thereof
JP5465006B2 (ja) * 2006-08-11 2014-04-09 ユニベルシテ・ドウ・ストラスブール キナーゼおよびｈｓｐ９０の阻害剤として有用な大環状化合物
US20110190237A1 (en) * 2008-01-15 2011-08-04 Nexgenix Pharmaceuticals Macrocyclic Prodrug Compounds Useful as Therapeutics
JP2011510017A (ja) * 2008-01-15 2011-03-31 ユニベルシテ・ドウ・ストラスブール 治療薬として有用なレゾルシン酸ラクトンの合成
JP5935055B2 (ja) * 2008-02-21 2016-06-15 オンコシナジー・インコーポレイテッド 治療薬として有用な大環状プロドラッグ化合物
WO2016196256A2 (en) 2015-06-04 2016-12-08 University Of North Carolina At Greensboro Non-aromatic difluoro analogues of resorcylic acid lactones

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4228079A (en) * 1978-10-30 1980-10-14 W. R. Grace & Co. Dialkoxy monorden derivatives
KR920000763A (ko) * 1990-06-06 1992-01-29 가와무라 요시부미 라디시콜 유도체, 그 제조방법 및 그의 항종양 활성
GB9225396D0 (en) * 1992-12-04 1993-01-27 Sandoz Ltd Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
WO1996033989A1 (en) 1996-10-31
JP3938936B2 (ja) 2007-06-27
EP0823429B1 (de) 2000-07-12
NO974890L (no) 1997-12-29
NZ311790A (en) 1999-04-29
HUP9901344A2 (hu) 2001-04-28
DE69609325D1 (de) 2000-08-17
EP0823429A1 (de) 1998-02-11
KR19990008051A (ko) 1999-01-25
CA2218981C (en) 2007-01-16
EP0823429A4 (de) 1998-07-08
AU6292796A (en) 1996-11-18
DE69609325T2 (de) 2000-11-23
AU700840B2 (en) 1999-01-14
NO974890D0 (no) 1997-10-23
HUP9901344A3 (en) 2001-05-28
US5977165A (en) 1999-11-02
ES2149468T3 (es) 2000-11-01
CA2218981A1 (en) 1996-10-31

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties