NO974890L - Radicicolderivater - Google Patents

Radicicolderivater

Info

Publication number: NO974890L
Authority: NO; Norway
Prior art keywords: hydrogen; alkenoyl; alkanoyl; same; derivatives
Prior art date: 1995-04-26

Application number

NO974890A

Other languages

English (en)

Norwegian (no)

Other versions

NO974890D0 (no

Inventor

Tsutomu Agatsuma

Yutaka Saitoh

Yoshinori Yamashita

Tamio Mizukami

Shiro Akinaga

Kasushige Gomi

Kazuhito Akasaka

Isami Takahashi

Original Assignee

Kyowa Hakko Kogyo Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-26

Filing date

1997-10-23

Publication date

1997-12-29

1997-10-23 Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk

1997-10-23 Publication of NO974890D0 publication Critical patent/NO974890D0/no

1997-12-29 Publication of NO974890L publication Critical patent/NO974890L/no

Links

229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000001589 carboacyl group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000001506 immunosuppresive effect Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
AECPBJMOGBFQDN-YMYQVXQQSA-N radicicol Chemical class C1CCCC(=O)C[C@H]2[C@H](Cl)C(=O)CC(=O)[C@H]2C(=O)O[C@H](C)C[C@H]2O[C@@H]21 AECPBJMOGBFQDN-YMYQVXQQSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001981 tert-butyldimethylsilyl group Chemical group [H]C([H])([H])[Si]([H])(C([H])([H])[H])[*]C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Oncology (AREA)
Transplantation (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Flanged Joints, Insulating Joints, And Other Joints (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO974890A 1995-04-26 1997-10-23 Radicicolderivater NO974890L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP10262695		1995-04-26
PCT/JP1996/001158 WO1996033989A1 (en)	1995-04-26	1996-04-26	Radicicol derivatives

Publications (2)

Publication Number	Publication Date
NO974890D0 NO974890D0 (no)	1997-10-23
NO974890L true NO974890L (no)	1997-12-29

Family

ID=14332458

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO974890A NO974890L (no)	1995-04-26	1997-10-23	Radicicolderivater

Country Status (13)

Country	Link
US (1)	US5977165A (de)
EP (1)	EP0823429B1 (de)
JP (1)	JP3938936B2 (de)
KR (1)	KR19990008051A (de)
AT (1)	ATE194610T1 (de)
AU (1)	AU700840B2 (de)
CA (1)	CA2218981C (de)
DE (1)	DE69609325T2 (de)
ES (1)	ES2149468T3 (de)
HU (1)	HUP9901344A3 (de)
NO (1)	NO974890L (de)
NZ (1)	NZ311790A (de)
WO (1)	WO1996033989A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ331062A (en)	1996-10-25	2000-05-26	Kyowa Hakko Kogyo Company Ltd	Radicicol derivatives or pharmacologically acceptable salts which show tyrosine kinase inhibition activity and have antitumor effects
JP2001510838A (ja) *	1997-07-25	2001-08-07	アメリカ合衆国	マクロサイクリックラクトン、組成物、および使用方法
WO1999055689A1 (en) *	1998-04-24	1999-11-04	Kyowa Hakko Kogyo Co., Ltd.	Radicicol derivatives
GB9822450D0 (en) *	1998-10-14	1998-12-09	Smithkline Beecham Plc	Medicaments
AU779438B2 (en)	1998-12-24	2005-01-27	Novation Pharmaceuticals Inc.	Compounds which affect mRNA stability and uses therefor
GB9914486D0 (en)	1999-06-21	1999-08-18	Smithkline Beecham Plc	Medicaments
GB9917408D0 (en)	1999-07-23	1999-09-22	Smithkline Beecham Plc	Compounds
GB9917406D0 (en)	1999-07-23	1999-09-22	Smithkline Beecham Plc	Compounds
CN1452619A (zh)	2000-07-26	2003-10-29	史密斯克莱·比奇曼公司	具有抗细菌活性的氨基哌啶喹啉和它们的氮杂等排的类似物
ATE328888T1 (de) *	2000-08-25	2006-06-15	Sloan Kettering Inst Cancer	Radicicol und monocillin und ihre analogen und ihre anwendungen
GB0101577D0 (en)	2001-01-22	2001-03-07	Smithkline Beecham Plc	Compounds
US7825094B2 (en) *	2001-05-23	2010-11-02	Sloan-Kettering Institute For Cancer Research	Method of treatment for cancers associated with elevated HER 2 levels
GB0112836D0 (en)	2001-05-25	2001-07-18	Smithkline Beecham Plc	Medicaments
GB0112834D0 (en)	2001-05-25	2001-07-18	Smithkline Beecham Plc	Medicaments
US20040192638A1 (en) *	2001-07-02	2004-09-30	Oaks John A.	Method and composition for prolonging the residence time of drugs in the gut
JP4445753B2 (ja)	2002-01-29	2010-04-07	グラクソグループリミテッド	アミノピペリジン誘導体
US7109213B2 (en)	2002-01-29	2006-09-19	Glaxo Group Limited	Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
AU2004251949B2 (en)	2003-06-27	2009-05-07	Kyowa Hakko Kirin Co., Ltd.	Hsp90 family protein inhibitors
JPWO2005018674A1 (ja) *	2003-08-22	2006-10-19	協和醗酵工業株式会社	イムノグロブリン遺伝子の転座を伴う疾患の治療薬
US20080108694A1 (en) *	2003-12-19	2008-05-08	Samuel J Danishefsky	Novel Macrocycles and Uses Thereof
JP5465006B2 (ja) *	2006-08-11	2014-04-09	ユニベルシテ・ドウ・ストラスブール	キナーゼおよびｈｓｐ９０の阻害剤として有用な大環状化合物
US20110190237A1 (en) *	2008-01-15	2011-08-04	Nexgenix Pharmaceuticals	Macrocyclic Prodrug Compounds Useful as Therapeutics
JP2011510017A (ja) *	2008-01-15	2011-03-31	ユニベルシテ・ドウ・ストラスブール	治療薬として有用なレゾルシン酸ラクトンの合成
JP5935055B2 (ja) *	2008-02-21	2016-06-15	オンコシナジー・インコーポレイテッド	治療薬として有用な大環状プロドラッグ化合物
WO2016196256A2 (en)	2015-06-04	2016-12-08	University Of North Carolina At Greensboro	Non-aromatic difluoro analogues of resorcylic acid lactones

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4228079A (en) *	1978-10-30	1980-10-14	W. R. Grace & Co.	Dialkoxy monorden derivatives
KR920000763A (ko) *	1990-06-06	1992-01-29	가와무라 요시부미	라디시콜 유도체, 그 제조방법 및 그의 항종양 활성
GB9225396D0 (en) *	1992-12-04	1993-01-27	Sandoz Ltd	Improvements in or relating to organic compounds

1996
- 1996-04-26 ES ES96912263T patent/ES2149468T3/es not_active Expired - Lifetime
- 1996-04-26 WO PCT/JP1996/001158 patent/WO1996033989A1/ja not_active Ceased
- 1996-04-26 AU AU62927/96A patent/AU700840B2/en not_active Ceased
- 1996-04-26 NZ NZ311790A patent/NZ311790A/en unknown
- 1996-04-26 KR KR1019970707575A patent/KR19990008051A/ko not_active Withdrawn
- 1996-04-26 JP JP53237396A patent/JP3938936B2/ja not_active Expired - Fee Related
- 1996-04-26 DE DE69609325T patent/DE69609325T2/de not_active Expired - Fee Related
- 1996-04-26 EP EP96912263A patent/EP0823429B1/de not_active Expired - Lifetime
- 1996-04-26 CA CA002218981A patent/CA2218981C/en not_active Expired - Fee Related
- 1996-04-26 HU HU9901344A patent/HUP9901344A3/hu unknown
- 1996-04-26 AT AT96912263T patent/ATE194610T1/de not_active IP Right Cessation
1997
- 1997-10-23 NO NO974890A patent/NO974890L/no not_active Application Discontinuation
- 1997-10-27 US US08/958,285 patent/US5977165A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO1996033989A1 (en)	1996-10-31
JP3938936B2 (ja)	2007-06-27
EP0823429B1 (de)	2000-07-12
NZ311790A (en)	1999-04-29
HUP9901344A2 (hu)	2001-04-28
DE69609325D1 (de)	2000-08-17
EP0823429A1 (de)	1998-02-11
ATE194610T1 (de)	2000-07-15
KR19990008051A (ko)	1999-01-25
CA2218981C (en)	2007-01-16
EP0823429A4 (de)	1998-07-08
AU6292796A (en)	1996-11-18
DE69609325T2 (de)	2000-11-23
AU700840B2 (en)	1999-01-14
NO974890D0 (no)	1997-10-23
HUP9901344A3 (en)	2001-05-28
US5977165A (en)	1999-11-02
ES2149468T3 (es)	2000-11-01
CA2218981A1 (en)	1996-10-31

Legal Events

Date	Code	Title	Description
2001-01-29	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
CA2218981A1 (en)	1996-10-31	Radicicol derivatives
AU4723997A (en)	1998-05-22	Radicicol derivatives
CA2112331A1 (en)	1994-06-29	Novel naphthalene derivatives
AU2685192A (en)	1993-05-03	Nitrogenous heterocyclic compound
NO981946L (no)	1998-06-29	Imidazoquinasolin derivater
CA2094300A1 (en)	1993-10-21	Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses
AU2267495A (en)	1995-11-16	Benzamide derivatives as vasopressin antagonists
CA2327679A1 (en)	1999-10-14	Triphendioxazine dyestuffs for dyeing organic substrates
MY117092A (en)	2004-05-31	Chemotherapeutic pyrrolocarbazole derivatives
CA2065799A1 (en)	1992-10-12	Thiazolidinedione derivatives, their production and their use
NO981393L (no)	1998-05-25	Guanidinoproteasehemmere
EP0711773A4 (de)	1996-06-19
DK1044203T3 (da)	2003-07-14	3'-epimere K-252a-derivater
EP0702014A4 (de)	1996-08-07	Dc-89 derivate
HUP0001792A2 (hu)	2000-12-28	Dibenzo-oxazepin- és -dioxepin-származékok, és felhasználásuk tumorellenes szerként
TW332143B (en)	1998-05-21	Carboxamide
YU78100A (sh)	2003-04-30	4,5,6 i 7-indol i indolin derivati, njihova izrada i upotreba
NO932418L (no)	1994-01-04	Pyrimidinderivater, fremgangsmaate for deres fremstilling og terapeutiske anvendelse derav
ATE215082T1 (de)	2002-04-15	Herboxidien-derivate und ihre herstellung aus einer streptomyces gex1 kultur
RU95112573A (ru)	1997-02-20	Способ получения 9-аминокамптотецина, промежуточные продукты, способ их получения и фармкомпозиция
CA2056793A1 (en)	1992-06-04	5-amino-5,6,7,8-tetrahydroquinolines and related compounds a process for their preparation and their use as medicaments
AU1219392A (en)	1992-09-17	Quinone derivatives
ZA99440B (en)	1999-07-21	Condensed aromatic heterocyclic cyclopentenopyridine derivative.
FI964278A0 (fi)	1996-10-24	Menetelmä 5,6-dihydroksi-2-amino-1,2,3,4-tetrahydronaftaleenin johdannaisten valmistamiseksi
AU4650099A (en)	2000-02-01	Lk6-a derivatives