ATE194918T1 - Behandlung von diabetes - Google Patents

Behandlung von diabetes

Info

Publication number: ATE194918T1
Authority: AT; Austria
Prior art keywords: peptide; diabetes; treatment; glucagon; insulin
Prior art date: 1994-05-12

Application number

AT95917874T

Other languages

English (en)

Inventor

John Dupre

Original Assignee

Amylin Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-12

Filing date

1995-05-12

Publication date

2000-08-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10755008&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE194918(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-05-12 Application filed by Amylin Pharmaceuticals Inc filed Critical Amylin Pharmaceuticals Inc

2000-08-15 Application granted granted Critical

2000-08-15 Publication of ATE194918T1 publication Critical patent/ATE194918T1/de

Links

206010012601 diabetes mellitus Diseases 0.000 title abstract 2
241000124008 Mammalia Species 0.000 abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 abstract 1
101800004266 Glucagon-like peptide 1(7-37) Proteins 0.000 abstract 1
102400000324 Glucagon-like peptide 1(7-37) Human genes 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
239000012634 fragment Substances 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
GCYXWQUSHADNBF-AAEALURTSA-N preproglucagon 78-108 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 GCYXWQUSHADNBF-AAEALURTSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Diabetes (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Emergency Medicine (AREA)
Child & Adolescent Psychology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Compounds Of Unknown Constitution (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT95917874T 1994-05-12 1995-05-12 Behandlung von diabetes ATE194918T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB9409496A GB9409496D0 (en)	1994-05-12	1994-05-12	Method for improving glycaemic control in diabetes
PCT/CA1995/000287 WO1995031214A1 (en)	1994-05-12	1995-05-12	Treatment of diabetes

Publications (1)

Publication Number	Publication Date
ATE194918T1 true ATE194918T1 (de)	2000-08-15

Family

ID=10755008

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95917874T ATE194918T1 (de)	1994-05-12	1995-05-12	Behandlung von diabetes

Country Status (13)

Country	Link
US (3)	US6899883B2 (de)
EP (1)	EP0762890B1 (de)
JP (2)	JPH10500114A (de)
AT (1)	ATE194918T1 (de)
AU (1)	AU711611B2 (de)
CA (1)	CA2190112A1 (de)
DE (1)	DE69518154T2 (de)
DK (1)	DK0762890T3 (de)
ES (1)	ES2150566T3 (de)
GB (1)	GB9409496D0 (de)
GR (1)	GR3034631T3 (de)
PT (1)	PT762890E (de)
WO (1)	WO1995031214A1 (de)

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1994
- 1994-05-12 GB GB9409496A patent/GB9409496D0/en active Pending
1995
- 1995-05-12 DK DK95917874T patent/DK0762890T3/da active
- 1995-05-12 JP JP7529262A patent/JPH10500114A/ja not_active Withdrawn
- 1995-05-12 WO PCT/CA1995/000287 patent/WO1995031214A1/en not_active Ceased
- 1995-05-12 AT AT95917874T patent/ATE194918T1/de not_active IP Right Cessation
- 1995-05-12 EP EP95917874A patent/EP0762890B1/de not_active Revoked
- 1995-05-12 CA CA002190112A patent/CA2190112A1/en not_active Withdrawn
- 1995-05-12 ES ES95917874T patent/ES2150566T3/es not_active Expired - Lifetime
- 1995-05-12 DE DE69518154T patent/DE69518154T2/de not_active Expired - Fee Related
- 1995-05-12 US US08/737,446 patent/US6899883B2/en not_active Expired - Fee Related
- 1995-05-12 PT PT95917874T patent/PT762890E/pt unknown
- 1995-05-12 AU AU24044/95A patent/AU711611B2/en not_active Withdrawn - After Issue
1999
- 1999-03-29 US US09/280,020 patent/US6989148B2/en not_active Expired - Fee Related
2000
- 2000-10-16 GR GR20000402317T patent/GR3034631T3/el not_active IP Right Cessation
2007
- 2007-02-08 JP JP2007029369A patent/JP2007131640A/ja active Pending
- 2007-12-04 US US11/987,771 patent/US20080286301A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20080286301A1 (en)	2008-11-20
PT762890E (pt)	2000-11-30
ES2150566T3 (es)	2000-12-01
WO1995031214A1 (en)	1995-11-23
US6899883B2 (en)	2005-05-31
GR3034631T3 (en)	2001-01-31
DE69518154T2 (de)	2000-12-14
EP0762890B1 (de)	2000-07-26
AU711611B2 (en)	1999-10-14
US20020119146A1 (en)	2002-08-29
DE69518154D1 (de)	2000-08-31
US6989148B2 (en)	2006-01-24
GB9409496D0 (en)	1994-06-29
EP0762890A1 (de)	1997-03-19
AU2404495A (en)	1995-12-05
JPH10500114A (ja)	1998-01-06
US20020160008A1 (en)	2002-10-31
CA2190112A1 (en)	1995-05-12
DK0762890T3 (da)	2000-11-13
JP2007131640A (ja)	2007-05-31

Legal Events

Date	Code	Title
2000-12-15	UEP	Publication of translation of european patent specification
2005-02-15	REN	Ceased due to non-payment of the annual fee
2007-07-15	RZN	Patent revoked
2007-08-15	RZN	Patent revoked

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DE69518154D1 (de)	2000-08-31	Behandlung von diabetes
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DE69224750D1 (de)	1998-04-16	Peptide und Antikörper zur Behandlung von rheumatoider Arthritis.
ATE128871T1 (de)	1995-10-15	Verfahren zur behandlung von thrombocytopenie und dafür geeignete pharmazeutische zusammensetzungen.
DE3162674D1 (en)	1984-04-19	A purified polypeptide, a process for its preparation, its use and pharmaceutical compositions containing it
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