ATE19627T1 - Substituierte pyrimidin-2-one, ihre salze, verfahren zu deren herstellung und diese enthaltende zusammensetzungen. - Google Patents

Substituierte pyrimidin-2-one, ihre salze, verfahren zu deren herstellung und diese enthaltende zusammensetzungen.

Info

Publication number
ATE19627T1
ATE19627T1 AT81303254T AT81303254T ATE19627T1 AT E19627 T1 ATE19627 T1 AT E19627T1 AT 81303254 T AT81303254 T AT 81303254T AT 81303254 T AT81303254 T AT 81303254T AT E19627 T1 ATE19627 T1 AT E19627T1
Authority
AT
Austria
Prior art keywords
group
compounds
salts
compositions containing
susceptible
Prior art date
Application number
AT81303254T
Other languages
English (en)
Inventor
Gordon Hanley Phillips
Christopher Williamson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE19627T1 publication Critical patent/ATE19627T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT81303254T 1980-07-15 1981-07-15 Substituierte pyrimidin-2-one, ihre salze, verfahren zu deren herstellung und diese enthaltende zusammensetzungen. ATE19627T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8023063 1980-07-15
EP81303254A EP0044704B1 (de) 1980-07-15 1981-07-15 Substituierte Pyrimidin-2-one, ihre Salze, Verfahren zu deren Herstellung und diese enthaltende Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE19627T1 true ATE19627T1 (de) 1986-05-15

Family

ID=10514771

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81303254T ATE19627T1 (de) 1980-07-15 1981-07-15 Substituierte pyrimidin-2-one, ihre salze, verfahren zu deren herstellung und diese enthaltende zusammensetzungen.

Country Status (12)

Country Link
US (1) US4636509A (de)
EP (1) EP0044704B1 (de)
JP (1) JPS5740471A (de)
AT (1) ATE19627T1 (de)
AU (1) AU7300381A (de)
CA (1) CA1160226A (de)
DE (1) DE3174554D1 (de)
DK (1) DK315281A (de)
ES (2) ES8301473A1 (de)
NO (1) NO812431L (de)
NZ (1) NZ197714A (de)
ZA (1) ZA814845B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58159479A (ja) * 1982-02-24 1983-09-21 ニユエガ−ド・アンド・コンパニ−・アクシエ／セルカペト 置換されたピリミジン−２−オン化合物
GB2135992B (en) * 1983-01-11 1986-09-24 Nyegaard & Co As Substituted pyrimidines and processes for their preparation
GB8420610D0 (en) * 1984-08-14 1984-09-19 Glaxo Group Ltd Chemical compounds
US4849426A (en) * 1987-05-15 1989-07-18 Pearlman Dale L Method for treating actinic keratosis with cytotoxic agents
US4853388A (en) * 1987-05-15 1989-08-01 Pearlman Dale L Method for treating psoriasis with cytotoxic agents
US4820711A (en) * 1987-05-15 1989-04-11 Pearlman Dale L Method for treating actinic keratosis with cytotoxic agents
US4855466A (en) * 1987-12-28 1989-08-08 E. R. Squibb & Sons, Inc. Purinyl cyclobutanes
US6334997B1 (en) 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
CN1087725C (zh) * 1994-03-25 2002-07-17 同位素技术有限公司 用氘代方法增强药物效果
EP1752452A4 (de) * 2004-06-04 2010-07-14 Astellas Pharma Inc Propan-1,3-dionderivat und dessen salz
RU2404973C2 (ru) * 2005-03-31 2010-11-27 Астеллас Фарма Инк. Производное соединение пропан-1,3-диона или его соль

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561290A (en) * 1975-10-16 1980-02-20 Nyegaard & Co As Pyrimid - 2 - ones
ES498337A0 (es) * 1980-01-07 1982-06-01 Nyegaard & Co As Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas
GB2080301B (en) * 1980-07-15 1984-04-18 Glaxo Group Ltd Substituted pyrimidin-2-ones the salts thereof processes for their preparation and pharmaceutical compositions containing them
GB2080300B (en) * 1980-07-15 1984-04-26 Glaxo Group Ltd Substituted pyrimidin-2-ones the salts thereof processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
CA1160226A (en) 1984-01-10
AU7300381A (en) 1982-01-21
US4636509A (en) 1987-01-13
DE3174554D1 (en) 1986-06-12
ZA814845B (en) 1983-02-23
NO812431L (no) 1982-01-18
JPS5740471A (en) 1982-03-06
ES8307758A1 (es) 1983-07-01
NZ197714A (en) 1984-11-09
EP0044704B1 (de) 1986-05-07
ES513177A0 (es) 1983-07-01
ES503984A0 (es) 1982-12-01
DK315281A (da) 1982-01-16
ES8301473A1 (es) 1982-12-01
EP0044704A1 (de) 1982-01-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee