ATE196802T1 - Zielspezifische screens und ihre verwendung zur ermittelung von kleinen organischen molekularen pharmakophoren - Google Patents

Zielspezifische screens und ihre verwendung zur ermittelung von kleinen organischen molekularen pharmakophoren

Info

Publication number
ATE196802T1
ATE196802T1 AT95930144T AT95930144T ATE196802T1 AT E196802 T1 ATE196802 T1 AT E196802T1 AT 95930144 T AT95930144 T AT 95930144T AT 95930144 T AT95930144 T AT 95930144T AT E196802 T1 ATE196802 T1 AT E196802T1
Authority
AT
Austria
Prior art keywords
small organic
antibodies
target
parts
domains
Prior art date
Application number
AT95930144T
Other languages
English (en)
Inventor
Arthur J Blume
Original Assignee
Dgi Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dgi Technologies Inc filed Critical Dgi Technologies Inc
Application granted granted Critical
Publication of ATE196802T1 publication Critical patent/ATE196802T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT95930144T 1994-08-03 1995-08-02 Zielspezifische screens und ihre verwendung zur ermittelung von kleinen organischen molekularen pharmakophoren ATE196802T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28608494A 1994-08-03 1994-08-03
US08/473,105 US6010861A (en) 1994-08-03 1995-06-07 Target specific screens and their use for discovering small organic molecular pharmacophores
PCT/US1995/010182 WO1996004557A2 (en) 1994-08-03 1995-08-02 Target specific screens and their use for discovering small organic molecular pharmacophores

Publications (1)

Publication Number Publication Date
ATE196802T1 true ATE196802T1 (de) 2000-10-15

Family

ID=26963579

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95930144T ATE196802T1 (de) 1994-08-03 1995-08-02 Zielspezifische screens und ihre verwendung zur ermittelung von kleinen organischen molekularen pharmakophoren

Country Status (8)

Country Link
US (3) US6010861A (de)
EP (2) EP1028315A3 (de)
JP (1) JPH10507517A (de)
AT (1) ATE196802T1 (de)
AU (1) AU3363195A (de)
CA (1) CA2196679A1 (de)
DE (1) DE69519033T2 (de)
WO (1) WO1996004557A2 (de)

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Also Published As

Publication number Publication date
US20040072271A1 (en) 2004-04-15
EP0774118B1 (de) 2000-10-04
US6010861A (en) 2000-01-04
WO1996004557A2 (en) 1996-02-15
EP1028315A2 (de) 2000-08-16
DE69519033T2 (de) 2001-05-17
US20030092057A1 (en) 2003-05-15
AU3363195A (en) 1996-03-04
WO1996004557A3 (en) 1996-04-25
DE69519033D1 (de) 2000-11-09
CA2196679A1 (en) 1996-02-15
JPH10507517A (ja) 1998-07-21
EP1028315A3 (de) 2004-01-02
EP0774118A2 (de) 1997-05-21

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