ATE220908T1 - Intracoronarer stent der quinazolinone derivate enthält - Google Patents

Intracoronarer stent der quinazolinone derivate enthält

Info

Publication number: ATE220908T1
Authority: AT; Austria
Prior art keywords: group; intracoronary stent; quinazolinone derivatives; stent containing; containing quinazolinone
Prior art date: 1996-08-30

Application number

AT97954887T

Other languages

English (en)

Inventor

Arnon Nagler

Shimon Slavin

Eli Hazum

Israel Vlodavsky

Ehud Geller

Mark Pines

Original Assignee

Agricultural Res Org

Hadasit Med Res Service

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-30

Filing date

1997-08-14

Publication date

2002-08-15

1996-08-30 Priority claimed from IL11916296A external-priority patent/IL119162A/xx

1997-08-14 Application filed by Agricultural Res Org, Hadasit Med Res Service filed Critical Agricultural Res Org

2002-08-15 Application granted granted Critical

2002-08-15 Publication of ATE220908T1 publication Critical patent/ATE220908T1/de

Links

AVRPFRMDMNDIDH-UHFFFAOYSA-N 1h-quinazolin-2-one Chemical class C1=CC=CC2=NC(O)=NC=C21 AVRPFRMDMNDIDH-UHFFFAOYSA-N 0.000 title abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
238000002399 angioplasty Methods 0.000 abstract 1
125000005605 benzo group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
-1 hydroxy, acetoxy Chemical group 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
208000037803 restenosis Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Vascular Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Surgery (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Materials For Medical Uses (AREA)
Plural Heterocyclic Compounds (AREA)

AT97954887T 1996-08-30 1997-08-14 Intracoronarer stent der quinazolinone derivate enthält ATE220908T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IL11916296A IL119162A (en)	1994-08-31	1996-08-30	Intracoronary stents containing quinazolinone derivatives
PCT/US1997/015254 WO1998023244A2 (en)	1996-08-30	1997-08-14	Intracoronary stents containing quinazolinone derivatives

Publications (1)

Publication Number	Publication Date
ATE220908T1 true ATE220908T1 (de)	2002-08-15

Family

ID=11069244

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97954887T ATE220908T1 (de)	1996-08-30	1997-08-14	Intracoronarer stent der quinazolinone derivate enthält

Country Status (8)

Country	Link
EP (1)	EP0936910B1 (de)
JP (1)	JP2001500040A (de)
CN (1)	CN1126534C (de)
AT (1)	ATE220908T1 (de)
AU (1)	AU712520B2 (de)
CA (1)	CA2253362C (de)
DE (1)	DE69714281T2 (de)
WO (1)	WO1998023244A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU4808997A (en)	1996-09-30	1998-04-24	Brigham And Women's Hospital	Methods and compounds for treatment of abnormal uterine bleeding
US7208010B2 (en)	2000-10-16	2007-04-24	Conor Medsystems, Inc.	Expandable medical device for delivery of beneficial agent
US7208011B2 (en)	2001-08-20	2007-04-24	Conor Medsystems, Inc.	Implantable medical device with drug filled holes
US6241762B1 (en)	1998-03-30	2001-06-05	Conor Medsystems, Inc.	Expandable medical device with ductile hinges
US8029561B1 (en)	2000-05-12	2011-10-04	Cordis Corporation	Drug combination useful for prevention of restenosis
CA2326828C (en) *	1998-05-05	2008-07-22	Boston Scientific Limited	Stent with smooth ends
US6290673B1 (en)	1999-05-20	2001-09-18	Conor Medsystems, Inc.	Expandable medical device delivery system and method
PT1328213E (pt)	2000-10-16	2005-10-31	Conor Medsystems Inc	Dispositivo medico expansivel para a administracao de um agente benefico
US20040073294A1 (en)	2002-09-20	2004-04-15	Conor Medsystems, Inc.	Method and apparatus for loading a beneficial agent into an expandable medical device
US6964680B2 (en)	2001-02-05	2005-11-15	Conor Medsystems, Inc.	Expandable medical device with tapered hinge
US7056338B2 (en)	2003-03-28	2006-06-06	Conor Medsystems, Inc.	Therapeutic agent delivery device with controlled therapeutic agent release rates
US7169179B2 (en)	2003-06-05	2007-01-30	Conor Medsystems, Inc.	Drug delivery device and method for bi-directional drug delivery
US7785653B2 (en)	2003-09-22	2010-08-31	Innovational Holdings Llc	Method and apparatus for loading a beneficial agent into an expandable medical device
CA2557524A1 (en) *	2004-02-25	2005-09-01	Collgard Biopharmaceuticals Ltd.	Biocompatible polymeric delivery systems for sustained release of quinazolinones
USD516723S1 (en)	2004-07-06	2006-03-07	Conor Medsystems, Inc.	Stent wall structure
US20070160640A1 (en) *	2006-01-12	2007-07-12	Eun-Hyun Jang	Halofuginone delivering vascular medical devices
US8883190B2 (en)	2006-12-01	2014-11-11	Wake Forest University Health Sciences	Urologic devices incorporating collagen inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3320124A (en) *	1964-07-20	1967-05-16	American Cyanamid Co	Method for treating coccidiosis with quinazolinones
DE2934069A1 (de) *	1979-08-23	1981-03-12	Hoechst Ag, 6000 Frankfurt	Mittel gegen theileriosen und seine verwendung.
US5133732A (en) *	1987-10-19	1992-07-28	Medtronic, Inc.	Intravascular stent
US5599352A (en) *	1992-03-19	1997-02-04	Medtronic, Inc.	Method of making a drug eluting stent
CA2113229C (en) *	1994-01-11	1999-04-20	Mark Pines	Anti-fibrotic quinazolinone-containing compositions and methods for the use thereof
IL110831A (en) *	1994-08-31	1998-12-27	Hadasit Med Res Service	Pharmaceutical compositions containing quinazolinone derivatives for preventing restenosis
US5593417A (en) *	1995-11-27	1997-01-14	Rhodes; Valentine J.	Intravascular stent with secure mounting means

1997
- 1997-08-14 AU AU67559/98A patent/AU712520B2/en not_active Ceased
- 1997-08-14 CA CA002253362A patent/CA2253362C/en not_active Expired - Fee Related
- 1997-08-14 CN CN97194218A patent/CN1126534C/zh not_active Expired - Fee Related
- 1997-08-14 WO PCT/US1997/015254 patent/WO1998023244A2/en not_active Ceased
- 1997-08-14 JP JP10520852A patent/JP2001500040A/ja active Pending
- 1997-08-14 EP EP97954887A patent/EP0936910B1/de not_active Expired - Lifetime
- 1997-08-14 AT AT97954887T patent/ATE220908T1/de not_active IP Right Cessation
- 1997-08-14 DE DE69714281T patent/DE69714281T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69714281D1 (de)	2002-08-29
CN1219125A (zh)	1999-06-09
AU712520B2 (en)	1999-11-11
AU6755998A (en)	1998-06-22
CA2253362C (en)	2003-05-06
JP2001500040A (ja)	2001-01-09
CA2253362A1 (en)	1998-06-04
EP0936910A2 (de)	1999-08-25
EP0936910B1 (de)	2002-07-24
WO1998023244A2 (en)	1998-06-04
CN1126534C (zh)	2003-11-05
WO1998023244A3 (en)	1998-09-17
DE69714281T2 (de)	2003-02-27
EP0936910A4 (de)	1999-08-25

Legal Events

Date	Code	Title	Description
2003-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69714281D1 (de)	2002-08-29	Intracoronarer stent der quinazolinone derivate enthält
ATE197401T1 (de)	2000-11-11	Chinazolinon-arzneimittel sowie deren verwendung
ATE180468T1 (de)	1999-06-15	Anthranilsäure derivate
FI931061A0 (fi)	1993-03-10	Metylen-oxindolderivat och foerfarande foer deras framstaellning
DE69831937D1 (de)	2006-03-02	Bicyclische protein-farnesyl-transferase inhibitoren
ES2176204T3 (es)	2002-12-01	Antidepresivos que contienen un derivado de xantina.
DE69220037D1 (de)	1997-07-03	Acridinderivate
ATE194335T1 (de)	2000-07-15	4,5-diaryloxazol-derivate
CA2305612A1 (en)	1999-04-22	Halogen substituted tetracyclic tetrahydrofuran derivatives
MY128323A (en)	2007-01-31	Thiazole derivatives for inhibition of cytokine production and of cell adhesion
ES2123756T3 (es)	1999-01-16	Derivados de piperazina.
ATE219481T1 (de)	2002-07-15	1,7,7-trimethyl-bicyclo(2.2.1)heptane derivative
DK0850062T3 (da)	2005-02-07	Anvendelse af halofuginon til fremstilling af et medikament til svækkelse af neovaskularisering og til behandling af maligne tumorer hos mennesker
MX9709465A (es)	1998-02-28	Derivados de bencimidazol 2-sustituidos como inhibidores de la proliferacion de celulas del musculo liso.
ES2065992T3 (es)	1995-03-01	Uso de derivados de imidazopirazol como analgesicos y agentes anti-inflamatorios.
DK0795326T3 (da)	2001-11-26	Okulærtensionssænkende middel
PT1023287E (pt)	2002-11-29	Derivados da 3-oxo-2(h)-1,2,4-triazina como ligandos dos receptores 5ht1a
AR019894A1 (es)	2002-03-20	Empleo de un derivado de tetrahidroxipiridina (0 4-hidroxipiridina) butilazol
ATE240329T1 (de)	2003-05-15	Zytotoxische pyrido(2,3,4-kl)acridinderivate, ihre herstellung und therapeutische verwendung
ATE257826T1 (de)	2004-01-15	Benzimidazolderivate und sie enthaltende medikamente
PL357193A1 (en)	2004-07-26	Oxy-and amino-substituted tetrahydrofuryl derivatives with antitumour activity
DE60009301D1 (en)	2004-04-29	Benzimidazolverbindungen
ECSP982641A (es)	1999-03-02	Ciertos acidos 5 - alquil-2-arilaminofenilaceticos y sus derivados