ATE197668T1 - Verwendung von beta-naphthochinonderivaten zur beschleunigung der proliferation der endothelzellen und inhibierung der no-synthasen - Google Patents

Verwendung von beta-naphthochinonderivaten zur beschleunigung der proliferation der endothelzellen und inhibierung der no-synthasen

Info

Publication number
ATE197668T1
ATE197668T1 AT94401460T AT94401460T ATE197668T1 AT E197668 T1 ATE197668 T1 AT E197668T1 AT 94401460 T AT94401460 T AT 94401460T AT 94401460 T AT94401460 T AT 94401460T AT E197668 T1 ATE197668 T1 AT E197668T1
Authority
AT
Austria
Prior art keywords
synthases
beta
endothelial cells
derivatives
naphthochinone
Prior art date
Application number
AT94401460T
Other languages
English (en)
Inventor
Christian Bloy
Jean-Pierre Cazenave
Bernard Hercelin
Bernard Teisseire
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of ATE197668T1 publication Critical patent/ATE197668T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94401460T 1993-07-02 1994-06-28 Verwendung von beta-naphthochinonderivaten zur beschleunigung der proliferation der endothelzellen und inhibierung der no-synthasen ATE197668T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9308111A FR2707494B1 (fr) 1993-07-02 1993-07-02 Nouvelle utilisation de dérivés de la béta-naphtoquinone ainsi que de leurs sels.

Publications (1)

Publication Number Publication Date
ATE197668T1 true ATE197668T1 (de) 2000-12-15

Family

ID=9448827

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94401460T ATE197668T1 (de) 1993-07-02 1994-06-28 Verwendung von beta-naphthochinonderivaten zur beschleunigung der proliferation der endothelzellen und inhibierung der no-synthasen

Country Status (13)

Country Link
US (1) US5478821A (de)
EP (1) EP0631776B1 (de)
JP (1) JP3993647B2 (de)
AT (1) ATE197668T1 (de)
CA (1) CA2127214C (de)
DE (1) DE69426316T2 (de)
DK (1) DK0631776T3 (de)
ES (1) ES2154285T3 (de)
FR (1) FR2707494B1 (de)
GR (1) GR3035059T3 (de)
HU (1) HU214716B (de)
PT (1) PT631776E (de)
RU (1) RU2131246C1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT758890E (pt) * 1994-05-11 2005-06-30 Jes Olesen Utilizacao de agentes de captura, inibidores ou antagonistas de no no tratamento da enxaqueca
FR2722507B1 (fr) * 1994-07-12 1996-08-14 Rhone Poulenc Rorer Sa Adenovirus comportant un gene codant pour une no synthase
EP0843550A1 (de) * 1995-08-09 1998-05-27 Ontogen Corporation Stickstoffmonoxid-synthase hemmer
WO1998036730A2 (de) * 1997-02-21 1998-08-27 Beiersdorf Ag Zubereitungen für die behandlung von rosacea
IT1312537B1 (it) * 1999-04-16 2002-04-22 Euphar Group Srl Derivati del (-)- verbenone.
JP4989830B2 (ja) * 1999-07-21 2012-08-01 サーントゥル ナシオナル ドゥ ラ ルシェルシュ シャーンティフィク 脳によるグルタミン酸塩の放出に対して抑制効果を示す薬剤を製造するためのベータ−ナフトキノン誘導体の使用
WO2018156917A1 (en) * 2017-02-23 2018-08-30 The Cleveland Clinic Foundation Anti-aging compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2395638A (en) * 1941-03-07 1946-02-26 Research Corp Hydroxylation of aromatic hydrocarbons
FR924M (de) * 1959-09-26 1961-11-13
US3758520A (en) * 1971-07-23 1973-09-11 C Beaudet Process for the preparation of beta-naphthoquinone semicarbazone
JPH037806A (ja) * 1989-06-05 1991-01-16 Masamoto Kaneko 廃棄物の処理方法及び装置

Also Published As

Publication number Publication date
EP0631776B1 (de) 2000-11-22
HU9401977D0 (en) 1994-09-28
FR2707494A1 (fr) 1995-01-20
EP0631776A1 (de) 1995-01-04
DE69426316T2 (de) 2001-05-03
RU2131246C1 (ru) 1999-06-10
RU94022756A (ru) 1996-09-10
HUT70507A (en) 1995-10-30
GR3035059T3 (en) 2001-03-30
DK0631776T3 (da) 2001-03-05
FR2707494B1 (fr) 1995-08-25
HU214716B (hu) 1998-05-28
DE69426316D1 (de) 2000-12-28
JPH07145129A (ja) 1995-06-06
CA2127214C (fr) 2004-10-26
JP3993647B2 (ja) 2007-10-17
PT631776E (pt) 2001-05-31
US5478821A (en) 1995-12-26
ES2154285T3 (es) 2001-04-01
CA2127214A1 (fr) 1995-01-03

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