ATE198548T1 - Verfahren zur umhüllung von nanopartikeln oder - tröpfchen - Google Patents

Verfahren zur umhüllung von nanopartikeln oder - tröpfchen

Info

Publication number
ATE198548T1
ATE198548T1 AT94925490T AT94925490T ATE198548T1 AT E198548 T1 ATE198548 T1 AT E198548T1 AT 94925490 T AT94925490 T AT 94925490T AT 94925490 T AT94925490 T AT 94925490T AT E198548 T1 ATE198548 T1 AT E198548T1
Authority
AT
Austria
Prior art keywords
solvent
polymer
droplets
preparing
particles
Prior art date
Application number
AT94925490T
Other languages
English (en)
Inventor
Mas Jose Alberto Vallet
Valdivia Francisco Javie Galan
Perdiguer Nuria Carreras
Original Assignee
Alcon Cusi S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Cusi S A filed Critical Alcon Cusi S A
Application granted granted Critical
Publication of ATE198548T1 publication Critical patent/ATE198548T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/22—Coating
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/795—Composed of biological material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/89—Deposition of materials, e.g. coating, cvd, or ald
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/89—Deposition of materials, e.g. coating, cvd, or ald
    • Y10S977/891—Vapor phase deposition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Luminescent Compositions (AREA)
  • Paints Or Removers (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Glanulating (AREA)
AT94925490T 1994-05-20 1994-09-30 Verfahren zur umhüllung von nanopartikeln oder - tröpfchen ATE198548T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09401121A ES2078190B1 (es) 1994-05-20 1994-05-20 Procedimiento para el recubrimiento de goticulas o particulas de tamaño nanometrico.
PCT/ES1994/000085 WO1995031975A1 (es) 1994-05-20 1994-09-30 Procedimiento para el recubrimiento de goticulas o particulas de tamaño nanometrico

Publications (1)

Publication Number Publication Date
ATE198548T1 true ATE198548T1 (de) 2001-01-15

Family

ID=8286348

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94925490T ATE198548T1 (de) 1994-05-20 1994-09-30 Verfahren zur umhüllung von nanopartikeln oder - tröpfchen

Country Status (21)

Country Link
US (1) US5851452A (de)
EP (1) EP0717989B1 (de)
JP (1) JPH09501101A (de)
KR (1) KR960703577A (de)
CN (1) CN1130868A (de)
AT (1) ATE198548T1 (de)
AU (1) AU696400B2 (de)
BG (1) BG100372A (de)
BR (1) BR9407333A (de)
CA (1) CA2167681A1 (de)
DE (1) DE69426568T2 (de)
DK (1) DK0717989T3 (de)
ES (1) ES2078190B1 (de)
FI (1) FI961348A7 (de)
GR (1) GR3035655T3 (de)
HU (1) HU9600386D0 (de)
NO (1) NO960232L (de)
OA (1) OA10257A (de)
PL (1) PL312666A1 (de)
PT (1) PT717989E (de)
WO (1) WO1995031975A1 (de)

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* Cited by examiner, † Cited by third party
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US5922403A (en) 1996-03-12 1999-07-13 Tecle; Berhan Method for isolating ultrafine and fine particles
US5945126A (en) * 1997-02-13 1999-08-31 Oakwood Laboratories L.L.C. Continuous microsphere process
ES2435944T3 (es) * 1997-06-27 2013-12-26 Abraxis Bioscience, Llc Nuevas formulaciones de agentes farmacológicos, métodos para su preparación y métodos para su uso
EP2000803A1 (de) * 1998-11-30 2008-12-10 Nanosphere, Inc. Nanoteilchen mit Polymerschalen
DE19856432A1 (de) * 1998-12-08 2000-06-15 Basf Ag Nanopartikuläre Kern-Schale Systeme sowie deren Verwendung in pharmazeutischen und kosmetischen Zubereitungen
FR2805761B1 (fr) * 2000-03-02 2002-08-30 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
WO2003037359A1 (en) * 2001-10-29 2003-05-08 Chengdu Somo Namotechnology Co., Ltd. Nanoparticle of insoluble medicinal components and method to produce thereof
US7053034B2 (en) * 2002-04-10 2006-05-30 Salvona, Llc Targeted controlled delivery compositions activated by changes in pH or salt concentration
EP2316567B1 (de) * 2003-09-26 2018-01-24 3M Innovative Properties Co. Nanoskalige Goldkatalysatoren, Aktivierungsmittel, Trägermedien und entsprechende Verfahren zur Herstellung von Katalysatorsystemen, im Besonderen beim Auftragen des Katalysators auf das Trägermedium mittels physikalischer Gasphasenabscheidung
DE602004006523T2 (de) * 2003-10-01 2008-01-31 Debio Recherche Pharmaceutique S.A. Vorrichtung und verfahren zur herstellung von partikeln
US8058202B2 (en) 2005-01-04 2011-11-15 3M Innovative Properties Company Heterogeneous, composite, carbonaceous catalyst system and methods that use catalytically active gold
KR20130079645A (ko) 2005-07-18 2013-07-10 유니버시티 오브 메사츄세츠 로웰 나노에멀젼 조성물 및 이의 제조 및 사용 방법
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
CN101374498A (zh) 2005-12-01 2009-02-25 麻萨诸塞州洛厄尔大学 肉毒杆菌纳米乳液
SG10201607909WA (en) 2006-12-01 2016-11-29 Anterios Inc Peptide nanoparticles and uses therefor
WO2008070538A2 (en) 2006-12-01 2008-06-12 Anterios, Inc. Micellar nanoparticles comprising botulinum toxin
CN101765423B (zh) 2007-05-31 2014-08-06 安特里奥公司 核酸纳米粒子和其用途
US8359820B2 (en) 2010-01-13 2013-01-29 Dohrmann Daniel R Ultra-low flow agricultural pump with unobstructed flow path and electronic flow control, tank refill indication, and detection of loss of flow
BR102015032910B1 (pt) 2015-12-29 2021-03-09 Companhia Nitro Química Brasileira processo de obtenção de uma dispersão coloidal, dispersão coloidal e seu uso
EP3510161A4 (de) 2016-08-23 2020-04-22 Akouos, Inc. Zusammensetzungen und verfahren zur behandlung von nicht altersbedingten hörschäden bei einer person
EP3541358A1 (de) 2016-11-21 2019-09-25 Eirion Therapeutics, Inc. Transdermale verabreichung von grossen wirkstoffen
JPWO2018180966A1 (ja) * 2017-03-28 2019-06-27 富士フイルム株式会社 マイクロカプセル及びその製造方法
US20200001263A1 (en) * 2018-06-28 2020-01-02 Cornell University Encapsulation System and Method
CN116096905A (zh) 2020-02-21 2023-05-09 阿库斯股份有限公司 用于治疗人受试者的非年龄相关性听力损伤的组合物和方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2909906A1 (de) * 1979-03-14 1980-10-02 Bayer Ag Verfahren zur kontinuierlichen herstellung von mikrokapseln
CH656884A5 (de) * 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
FR2608942B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules
FR2608988B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
US5021248A (en) * 1988-09-19 1991-06-04 Enzytech, Inc. Hydrophobic protein microparticles and preparation thereof
FR2663222A1 (fr) * 1990-06-13 1991-12-20 Medgenix Group Sa Microcapsule de liquide huileux.
KR930006431B1 (ko) * 1990-10-11 1993-07-16 재단법인 한국화학연구소 약물의 미세캡슐화 방법
ES2034891B1 (es) * 1991-08-08 1993-12-16 Cusi Lab Procedimiento de elaboracion en continuo de sistemas coloidales dispersos, en forma de nanocapsulas o nanoparticulas.
AU651268B2 (en) * 1992-02-18 1994-07-14 Idemitsu Kosan Co. Ltd Mannich reaction product and process for producing the same and use of the product
CA2136630A1 (en) * 1992-06-08 1993-12-23 John E. Waylet, Jr. Liquid dispensing system
FR2692167B1 (fr) * 1992-06-16 1994-09-16 Centre Nat Rech Scient Préparation et application de nouveaux systèmes colloïdaux nanovésiculaires dispersibles à base de cyclodextrine, sous forme de nanocapsules.

Also Published As

Publication number Publication date
HU9600386D0 (en) 1996-04-29
AU696400B2 (en) 1998-09-10
EP0717989A1 (de) 1996-06-26
FI961348A0 (fi) 1996-03-25
PL312666A1 (en) 1996-04-29
US5851452A (en) 1998-12-22
CA2167681A1 (en) 1995-11-30
GR3035655T3 (en) 2001-06-29
FI961348L (fi) 1996-03-25
NO960232D0 (no) 1996-01-19
DE69426568D1 (de) 2001-02-15
DE69426568T2 (de) 2001-08-23
EP0717989B1 (de) 2001-01-10
PT717989E (pt) 2001-06-29
HK1017807A1 (en) 1999-11-26
BG100372A (en) 1996-12-31
OA10257A (en) 1997-10-07
ES2078190B1 (es) 1996-08-01
ES2078190A1 (es) 1995-12-01
NO960232L (no) 1996-03-19
WO1995031975A1 (es) 1995-11-30
AU7537994A (en) 1995-12-18
DK0717989T3 (da) 2001-05-21
JPH09501101A (ja) 1997-02-04
BR9407333A (pt) 1996-06-18
CN1130868A (zh) 1996-09-11
FI961348A7 (fi) 1996-03-25
KR960703577A (ko) 1996-08-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee