ATE200286T1 - Chinolincarbonsäure-derivate - Google Patents

Chinolincarbonsäure-derivate

Info

Publication number
ATE200286T1
ATE200286T1 AT95918742T AT95918742T ATE200286T1 AT E200286 T1 ATE200286 T1 AT E200286T1 AT 95918742 T AT95918742 T AT 95918742T AT 95918742 T AT95918742 T AT 95918742T AT E200286 T1 ATE200286 T1 AT E200286T1
Authority
AT
Austria
Prior art keywords
acid derivatives
carbonic acid
quinoline
quinoline carbonic
group
Prior art date
Application number
AT95918742T
Other languages
English (en)
Inventor
Yutaka Ohuchi
Masaji Suzuki
Hajime Asanuma
Sadakazu Yokomori
Katsuo Hatayama
Original Assignee
Syngenta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Ltd filed Critical Syngenta Ltd
Application granted granted Critical
Publication of ATE200286T1 publication Critical patent/ATE200286T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
AT95918742T 1994-05-18 1995-05-18 Chinolincarbonsäure-derivate ATE200286T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10317794 1994-05-18
PCT/JP1995/000954 WO1995031455A1 (en) 1994-05-18 1995-05-18 Quinolinecarboxylic acid derivative

Publications (1)

Publication Number Publication Date
ATE200286T1 true ATE200286T1 (de) 2001-04-15

Family

ID=14347238

Family Applications (2)

Application Number Title Priority Date Filing Date
AT95918742T ATE200286T1 (de) 1994-05-18 1995-05-18 Chinolincarbonsäure-derivate
AT99123695T ATE316970T1 (de) 1994-05-18 1995-05-18 8-(2,2,2-trifluoroethyl)-8-azabicyclo(3.2.1)oct n-3-on verwendbar als zwischenprodukt für serotonin-4-rezeptor stimulierende chinolincarbonsäure- derivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT99123695T ATE316970T1 (de) 1994-05-18 1995-05-18 8-(2,2,2-trifluoroethyl)-8-azabicyclo(3.2.1)oct n-3-on verwendbar als zwischenprodukt für serotonin-4-rezeptor stimulierende chinolincarbonsäure- derivate

Country Status (11)

Country Link
US (1) US5753673A (de)
EP (2) EP0710662B1 (de)
JP (1) JP3829879B2 (de)
KR (1) KR960703907A (de)
AT (2) ATE200286T1 (de)
AU (1) AU685632B2 (de)
CA (1) CA2167055A1 (de)
DE (2) DE69520545T2 (de)
DK (1) DK1018513T3 (de)
ES (1) ES2252907T3 (de)
WO (1) WO1995031455A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2184366A1 (en) * 1994-02-28 1995-08-31 Yutaka Ohuchi Heterocyclic compound
WO1997018210A1 (en) * 1995-11-13 1997-05-22 Smithkline Beecham Corporation Hemoregulatory compounds
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US20050222175A1 (en) * 2004-03-31 2005-10-06 Dhanoa Dale S New piperidinylamino-thieno[2,3-D] pyrimidine compounds
US7612078B2 (en) * 2003-03-31 2009-11-03 Epix Delaware, Inc. Piperidinylamino-thieno[2,3-D] pyrimidine compounds
CA2545092C (en) * 2003-11-24 2010-08-17 Pfizer Inc. Quinolonecarboxylic acid compounds having 5-ht4 receptor agonistic activity
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) * 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US7488736B2 (en) * 2004-05-17 2009-02-10 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7576211B2 (en) 2004-09-30 2009-08-18 Epix Delaware, Inc. Synthesis of thienopyridinone compounds and related intermediates
US7598265B2 (en) * 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
US7407966B2 (en) * 2004-10-07 2008-08-05 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
EP1807423B1 (de) * 2004-11-05 2009-05-20 Theravance, Inc. Chinolinon-carboxamid-verbindungen
ES2332808T3 (es) * 2004-11-05 2010-02-12 Theravance, Inc. Compuestos agonistas del receptor 5-ht4.
MX2007007818A (es) * 2004-12-22 2007-09-11 Theravance Inc Compuestos de indazol-carboxamida.
WO2006088988A1 (en) * 2005-02-17 2006-08-24 Theravance, Inc. Crystalline form of an indazole-carboxamide compound
ES2523851T3 (es) * 2005-03-02 2014-12-02 Theravance Biopharma R&D Ip, Llc Compuestos de quinolinona como agonistas de los receptores 5-HT4
TWI377206B (en) 2005-04-06 2012-11-21 Theravance Inc Crystalline form of a quinolinone-carboxamide compound
US7317022B2 (en) * 2005-06-07 2008-01-08 Theravance, Inc. Benzoimidazolone-carboxamide compounds as 5-HT4 receptors agonists
MY143574A (en) * 2005-11-22 2011-05-31 Theravance Inc Carbamate compounds as 5-ht4 receptor agonists
US7487406B2 (en) * 2005-11-29 2009-02-03 International Business Machines Corporation Systems, methods, and media for managing software defects
JP5237121B2 (ja) * 2006-02-16 2013-07-17 セラヴァンス， インコーポレーテッド ５−ｈｔ４受容体アゴニスト化合物に対する中間体を調製するためのプロセス
TWI415850B (zh) 2007-07-20 2013-11-21 Theravance Inc 製備ｍｕ類鴉片受體拮抗劑之中間物的方法
EP2445877B1 (de) * 2008-12-03 2014-07-23 Nanotherapeutics, Inc. Bicyclische verbindungen und verfahren zu deren herstellung und deren verwendung
TWI471095B (zh) 2009-12-21 2015-02-01 Nippon Soda Co 環胺化合物及殺蟎劑
AR081721A1 (es) 2010-02-25 2012-10-17 Nippon Soda Co Compuesto de amina ciclica y acaricida
WO2011116491A1 (zh) * 2010-03-22 2011-09-29 北京世纪迈劲生物科技有限公司 制备二苯乙醇酸去甲托品酯和其盐的方法及其中所用的中间体
JP5767099B2 (ja) * 2011-06-16 2015-08-19 日本曹達株式会社 環状アミン化合物および有害生物防除剤
JP2022515610A (ja) * 2018-12-27 2022-02-21 エフ．ホフマン－ラ ロシュ アーゲー ｅｘｏ－ｔｅｒｔ－ブチルＮ－（３－アザビシクロ［３．２．１］オクタン－８－イル）カルバミン酸塩の調製のためのプロセス

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1228293B (it) * 1989-02-06 1991-06-07 Angeli Inst Spa Benzoderivati di composti eterociclici contenenti azoto.
JP3122671B2 (ja) * 1990-05-23 2001-01-09 協和醗酵工業株式会社 複素環式化合物
CA2097815C (en) * 1990-12-28 2001-04-17 Fumio Suzuki Quinoline derivative
EP0670319A4 (de) * 1992-11-20 1996-01-17 Thaisho Pharmaceutical Co Ltd Heterocyclische verbindungen.

Also Published As

Publication number Publication date
US5753673A (en) 1998-05-19
JP3829879B2 (ja) 2006-10-04
EP0710662A4 (de) 1996-09-18
AU685632B2 (en) 1998-01-22
DK1018513T3 (da) 2006-04-03
DE69534768D1 (de) 2006-04-13
ATE316970T1 (de) 2006-02-15
WO1995031455A1 (en) 1995-11-23
DE69520545D1 (de) 2001-05-10
CA2167055A1 (en) 1995-11-23
ES2252907T3 (es) 2006-05-16
AU2454895A (en) 1995-12-05
EP1018513B1 (de) 2006-02-01
EP1018513A2 (de) 2000-07-12
EP0710662A1 (de) 1996-05-08
EP1018513A3 (de) 2004-07-21
DE69520545T2 (de) 2001-08-09
EP0710662B1 (de) 2001-04-04
JPH0834784A (ja) 1996-02-06
KR960703907A (ko) 1996-08-31
DE69534768T2 (de) 2007-02-01

Similar Documents

Publication Publication Date Title
ATE200286T1 (de) Chinolincarbonsäure-derivate
ID22447A (id) Senyawa gula, bahan pengegel, komposisi bahan pengegel, proses penyediaannya serta komposisi gel
ES2101960T3 (es) Lactamas benzo-condensadas.
AU4523797A (en) Atherosclerosis treatment
EP0632031A4 (de)
PT918776E (pt) Sintese total de acilfulvenos antitumorais
BR8202861A (pt) Composto composicao farmaceutica processo para baixar a pressao sanguinea de seres humanos processo para preparar um composto e process para preparar uma composicao farmaceutica
PL309874A1 (en) Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
EP0640601A4 (de) Benzamid-derivate.
DK0615549T3 (da) Fremgangsmåde til fremstilling af farmaceutisk aktive thiazolidin- eller oxazolidinforbindelser med en gærreduktase
EP0712398A1 (de) Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen
NO904031L (no) Fremgangsmaate ved fremstilling av beta-karbonyl-karboksyamider av 1,3-tiazolidiner.
AU4271389A (en) Phenylalkyl or phenylalkoxyethyl substituted piperazine derivatives
ATE245147T1 (de) Substituierte aminochinazolinon (thion) derivate
HRP20000027B1 (en) Process for the preparation of alkoxyfuranoneamine derivatives, compounds obtained by this process, and the use of these compounds
DE69123757D1 (de) Epoxysuccinamidsäurederivat
GB8606105D0 (en) Chemical compounds
AU664093B2 (en) Arylpiperidine and arylpiperazine alkylbenzyl alcohol derivatives as antipsychotics
PH31474A (en) N-aminoboalkyl-substituted nitrogen-containing five membered heterocyclic compounds.
PT99331B (pt) Processo para a preparacao de 3-difenilmetoxi-8-azabiciclo{3.2.1}octilalquil-tiazolidinomas e de composicoes farmaceuticas que as contem
ES2110974T3 (es) Procedimiento para la preparacion de (s)-vinil y de (s)-alenil-gaba.
NO853968L (no) Mellomprodukter for fremstilling av 16-fenoksy- og 16-subs tituerte fenoksyprostatriensyrederivater.
DE3778088D1 (de) Substituierte pyrimidochinoxaline.
ES2077697T3 (es) Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.
DE69707793D1 (de) Alkynylaminosäure Derivate und ihre Verwendung als pharmazeutische Verbindungen