ATE207742T1 - Heterodisperse hydrogelsysteme zur verzögerten freisetzung unlöslicher arzneistoffe - Google Patents
Heterodisperse hydrogelsysteme zur verzögerten freisetzung unlöslicher arzneistoffeInfo
- Publication number
- ATE207742T1 ATE207742T1 AT94401925T AT94401925T ATE207742T1 AT E207742 T1 ATE207742 T1 AT E207742T1 AT 94401925 T AT94401925 T AT 94401925T AT 94401925 T AT94401925 T AT 94401925T AT E207742 T1 ATE207742 T1 AT E207742T1
- Authority
- AT
- Austria
- Prior art keywords
- delayed release
- sustained release
- medicinal substances
- hydrogel systems
- insoluble medicinal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/118,924 US5455046A (en) | 1993-09-09 | 1993-09-09 | Sustained release heterodisperse hydrogel systems for insoluble drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE207742T1 true ATE207742T1 (de) | 2001-11-15 |
Family
ID=22381584
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94401925T ATE207742T1 (de) | 1993-09-09 | 1994-08-30 | Heterodisperse hydrogelsysteme zur verzögerten freisetzung unlöslicher arzneistoffe |
| AT01104276T ATE318586T1 (de) | 1993-09-09 | 1994-08-30 | Heterodisperse hydrogelsysteme zur verzögerten freisetzung unlöslicher arzneistoffe |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01104276T ATE318586T1 (de) | 1993-09-09 | 1994-08-30 | Heterodisperse hydrogelsysteme zur verzögerten freisetzung unlöslicher arzneistoffe |
Country Status (11)
| Country | Link |
|---|---|
| US (6) | US5455046A (de) |
| EP (2) | EP0642785B1 (de) |
| JP (1) | JP4077886B2 (de) |
| AT (2) | ATE207742T1 (de) |
| CA (1) | CA2131647C (de) |
| DE (3) | DE69434640T2 (de) |
| DK (1) | DK0642785T3 (de) |
| ES (2) | ES2070810T3 (de) |
| GR (1) | GR950300035T1 (de) |
| IL (1) | IL110744A (de) |
| PT (2) | PT1101489E (de) |
Families Citing this family (103)
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| US5662933A (en) * | 1993-09-09 | 1997-09-02 | Edward Mendell Co., Inc. | Controlled release formulation (albuterol) |
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| US6726930B1 (en) * | 1993-09-09 | 2004-04-27 | Penwest Pharmaceuticals Co. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
| US5773025A (en) * | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
| US6183778B1 (en) | 1993-09-21 | 2001-02-06 | Jagotec Ag | Pharmaceutical tablet capable of liberating one or more drugs at different release rates |
| US5399358A (en) * | 1993-11-12 | 1995-03-21 | Edward Mendell Co., Inc. | Sustained release formulations for 24 hour release of metroprolol |
| US5399359A (en) * | 1994-03-04 | 1995-03-21 | Edward Mendell Co., Inc. | Controlled release oxybutynin formulations |
| US5399362A (en) * | 1994-04-25 | 1995-03-21 | Edward Mendell Co., Inc. | Once-a-day metoprolol oral dosage form |
| WO1995028916A1 (en) * | 1994-04-25 | 1995-11-02 | Edward Mendell Co., Inc. | Sustained release excipient |
| NZ270439A (en) * | 1995-02-02 | 1996-04-26 | Bernard Charles Sherman | Solid slow release pharmaceutical composition: carrier is polyethylene glycol and hydrophilic gel-forming polymer |
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| AU695734B2 (en) | 1996-07-08 | 1998-08-20 | Penwest Pharmaceuticals Co. | Sustained release matrix for high-dose insoluble drugs |
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| US6056977A (en) | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
| US6337091B1 (en) | 1997-10-27 | 2002-01-08 | Temple University - Of The Commonwealth System Of Higher Education | Matrix for controlled delivery of highly soluble pharmaceutical agents |
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| US9308196B2 (en) | 2012-05-18 | 2016-04-12 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam |
| US9320725B2 (en) | 2012-05-18 | 2016-04-26 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid |
| US20130310385A1 (en) | 2012-05-18 | 2013-11-21 | Gruenenthal Gmbh | Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants |
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-
1993
- 1993-09-09 US US08/118,924 patent/US5455046A/en not_active Expired - Lifetime
-
1994
- 1994-08-22 IL IL11074494A patent/IL110744A/en not_active IP Right Cessation
- 1994-08-30 EP EP94401925A patent/EP0642785B1/de not_active Expired - Lifetime
- 1994-08-30 DE DE69434640T patent/DE69434640T2/de not_active Expired - Fee Related
- 1994-08-30 DE DE69428853T patent/DE69428853T2/de not_active Expired - Lifetime
- 1994-08-30 DE DE0642785T patent/DE642785T1/de active Pending
- 1994-08-30 ES ES94401925T patent/ES2070810T3/es not_active Expired - Lifetime
- 1994-08-30 AT AT94401925T patent/ATE207742T1/de not_active IP Right Cessation
- 1994-08-30 AT AT01104276T patent/ATE318586T1/de not_active IP Right Cessation
- 1994-08-30 PT PT01104276T patent/PT1101489E/pt unknown
- 1994-08-30 EP EP01104276A patent/EP1101489B1/de not_active Expired - Lifetime
- 1994-08-30 ES ES01104276T patent/ES2254274T3/es not_active Expired - Lifetime
- 1994-08-30 PT PT94401925T patent/PT642785E/pt unknown
- 1994-08-30 DK DK94401925T patent/DK0642785T3/da active
- 1994-09-08 CA CA002131647A patent/CA2131647C/en not_active Expired - Lifetime
- 1994-09-09 JP JP24076694A patent/JP4077886B2/ja not_active Expired - Fee Related
-
1995
- 1995-05-22 US US08/447,236 patent/US5554387A/en not_active Expired - Lifetime
- 1995-05-22 US US08/447,235 patent/US5512297A/en not_active Expired - Lifetime
- 1995-07-31 GR GR950300035T patent/GR950300035T1/el unknown
-
1996
- 1996-05-21 US US08/651,901 patent/US5667801A/en not_active Expired - Lifetime
-
1997
- 1997-04-18 US US08/843,573 patent/US5846563A/en not_active Expired - Lifetime
-
1998
- 1998-12-08 US US09/207,298 patent/US6136343A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2070810T3 (es) | 2001-12-16 |
| US5846563A (en) | 1998-12-08 |
| PT642785E (pt) | 2002-02-28 |
| DE69428853D1 (de) | 2001-12-06 |
| ES2070810T1 (es) | 1995-06-16 |
| US5554387A (en) | 1996-09-10 |
| ATE318586T1 (de) | 2006-03-15 |
| DE642785T1 (de) | 1995-09-28 |
| ES2254274T3 (es) | 2006-06-16 |
| DK0642785T3 (da) | 2001-12-31 |
| US6136343A (en) | 2000-10-24 |
| GR950300035T1 (en) | 1995-07-31 |
| DE69434640T2 (de) | 2006-08-10 |
| IL110744A (en) | 1998-12-27 |
| PT1101489E (pt) | 2006-05-31 |
| CA2131647C (en) | 1999-08-10 |
| CA2131647A1 (en) | 1995-03-10 |
| US5455046A (en) | 1995-10-03 |
| EP0642785A3 (de) | 1996-11-06 |
| JP4077886B2 (ja) | 2008-04-23 |
| US5667801A (en) | 1997-09-16 |
| DE69434640D1 (de) | 2006-04-27 |
| DE69428853T2 (de) | 2002-04-11 |
| EP1101489B1 (de) | 2006-03-01 |
| EP1101489A3 (de) | 2001-09-19 |
| EP0642785B1 (de) | 2001-10-31 |
| EP0642785A2 (de) | 1995-03-15 |
| IL110744A0 (en) | 1994-08-22 |
| US5512297A (en) | 1996-04-30 |
| JPH07165615A (ja) | 1995-06-27 |
| EP1101489A2 (de) | 2001-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEFA | Change of the company name | ||
| REN | Ceased due to non-payment of the annual fee |