MX9400254A - Composicion farmaceutica para el tratamiento de la aterosclerosis. - Google Patents

Composicion farmaceutica para el tratamiento de la aterosclerosis.

Info

Publication number: MX9400254A
Authority: MX; Mexico
Prior art keywords: treatment; atherosclerosis; pharmaceutical composition; ester; dihydroequilin
Prior art date: 1993-01-05

Application number

MX9400254A

Other languages

English (en)

Spanish (es)

Inventor

Steven Jay Adelman

Kurt Edric Steiner

Original Assignee

American Home Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-05

Filing date

1994-01-04

Publication date

1994-08-31

1993-12-01 Priority claimed from US08/157,661 external-priority patent/US5482935A/en

1994-01-04 Application filed by American Home Prod filed Critical American Home Prod

1994-08-31 Publication of MX9400254A publication Critical patent/MX9400254A/es

Links

201000001320 Atherosclerosis Diseases 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
-1 alkanoyloxy ester Chemical class 0.000 abstract 4
229910019142 PO4 Inorganic materials 0.000 abstract 2
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 2
NLLMJANWPUQQTA-SPUZQDLCSA-N estra-1,3,5(10),7-tetraene-3,17alpha-diol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@@H](CC4)O)[C@@H]4C3=CCC2=C1 NLLMJANWPUQQTA-SPUZQDLCSA-N 0.000 abstract 2
230000001076 estrogenic effect Effects 0.000 abstract 2
239000010452 phosphate Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
150000003431 steroids Chemical class 0.000 abstract 2
230000000879 anti-atherosclerotic effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Steroid Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)
Medicinal Preparation (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

MX9400254A 1993-01-05 1994-01-04 Composicion farmaceutica para el tratamiento de la aterosclerosis. MX9400254A (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US77793A	1993-01-05	1993-01-05
US08/157,661 US5482935A (en)	1993-01-05	1993-12-01	Anti-atherosclerotic use of 17 alpha-dihydroequilin

Publications (1)

Publication Number	Publication Date
MX9400254A true MX9400254A (es)	1994-08-31

Family

ID=26668138

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX9400254A MX9400254A (es)	1993-01-05	1994-01-04	Composicion farmaceutica para el tratamiento de la aterosclerosis.

Country Status (16)

Country	Link
EP (1)	EP0678027B1 (de)
JP (1)	JP3344585B2 (de)
CN (1)	CN1071573C (de)
AT (1)	ATE209495T1 (de)
AU (1)	AU6015794A (de)
CA (1)	CA2152187A1 (de)
CY (1)	CY2361B1 (de)
DE (1)	DE69331237T2 (de)
DK (1)	DK0678027T3 (de)
ES (1)	ES2165382T3 (de)
IL (1)	IL108155A (de)
MX (1)	MX9400254A (de)
PH (1)	PH30474A (de)
PT (1)	PT678027E (de)
SG (1)	SG52359A1 (de)
WO (1)	WO1994015612A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6855703B1 (en) *	2000-03-10	2005-02-15	Endeavor Pharmaceuticals	Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3436411A (en)	1967-12-28	1969-04-01	American Home Prod	Process for cleaving an a-ring ether group in 13-alkylgona (and 8-isogona)-1,3,5(10)-trienes and delta-7-,delta-8(9)-,and delta-8(9),14(15)-dehydro derivatives thereof
US3507889A (en) *	1968-06-11	1970-04-21	American Home Prod	Process for the preparation of 17alpha-dihydroequilenin and related compounds
US3608075A (en) *	1969-07-28	1971-09-21	American Home Prod	Compositions and methods of treating the menopausal syndrome
US3646076A (en)	1970-06-02	1972-02-29	American Home Prod	Process for ethynylating 17-keto steroidal phenols
US4154820A (en) *	1976-02-23	1979-05-15	Akzona Incorporated	Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers
US4379780A (en) *	1980-09-29	1983-04-12	American Home Products Corporation	17 α-Dihydroequilin hapten and assay method

1993
- 1993-12-22 DK DK94906461T patent/DK0678027T3/da active
- 1993-12-22 ES ES94906461T patent/ES2165382T3/es not_active Expired - Lifetime
- 1993-12-22 AT AT94906461T patent/ATE209495T1/de not_active IP Right Cessation
- 1993-12-22 EP EP94906461A patent/EP0678027B1/de not_active Expired - Lifetime
- 1993-12-22 AU AU60157/94A patent/AU6015794A/en not_active Abandoned
- 1993-12-22 SG SG1996003424A patent/SG52359A1/en unknown
- 1993-12-22 DE DE69331237T patent/DE69331237T2/de not_active Expired - Fee Related
- 1993-12-22 PT PT94906461T patent/PT678027E/pt unknown
- 1993-12-22 CA CA002152187A patent/CA2152187A1/en not_active Abandoned
- 1993-12-22 JP JP51605594A patent/JP3344585B2/ja not_active Expired - Fee Related
- 1993-12-22 WO PCT/US1993/012559 patent/WO1994015612A1/en not_active Ceased
- 1993-12-23 IL IL10815593A patent/IL108155A/en not_active IP Right Cessation
- 1993-12-28 PH PH47563A patent/PH30474A/en unknown
1994
- 1994-01-04 MX MX9400254A patent/MX9400254A/es not_active IP Right Cessation
- 1994-01-04 CN CN94100239A patent/CN1071573C/zh not_active Expired - Fee Related
2003
- 2003-05-15 CY CY0300043A patent/CY2361B1/xx unknown

Also Published As

Publication number	Publication date
EP0678027B1 (de)	2001-11-28
DK0678027T3 (da)	2002-03-18
ES2165382T3 (es)	2002-03-16
CA2152187A1 (en)	1994-07-21
JPH08505392A (ja)	1996-06-11
HK1011282A1 (en)	1999-07-09
SG52359A1 (en)	1998-09-28
PH30474A (en)	1997-05-28
DE69331237T2 (de)	2002-06-13
CY2361B1 (en)	2004-06-04
WO1994015612A1 (en)	1994-07-21
IL108155A (en)	1999-08-17
DE69331237D1 (de)	2002-01-10
JP3344585B2 (ja)	2002-11-11
EP0678027A1 (de)	1995-10-25
IL108155A0 (en)	1994-04-12
PT678027E (pt)	2002-04-29
ATE209495T1 (de)	2001-12-15
AU6015794A (en)	1994-08-15
CN1096443A (zh)	1994-12-21
CN1071573C (zh)	2001-09-26

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Legal Events

Date	Code	Title	Description
1999-06-24	FG	Grant or registration
2004-12-31	HC	Change of company name or juridical status	Owner name: BASF AGRO B.V., ARNHEM (NL), WAEDENSWIL-BRANCH
2015-04-30	MM	Annulment or lapse due to non-payment of fees