ATE210676T1 - Verfahren zur herstellung von 2'-deoxy-2'- halocoformycin oder stereoisomere davon - Google Patents

Verfahren zur herstellung von 2'-deoxy-2'- halocoformycin oder stereoisomere davon

Info

Publication number
ATE210676T1
ATE210676T1 AT97400511T AT97400511T ATE210676T1 AT E210676 T1 ATE210676 T1 AT E210676T1 AT 97400511 T AT97400511 T AT 97400511T AT 97400511 T AT97400511 T AT 97400511T AT E210676 T1 ATE210676 T1 AT E210676T1
Authority
AT
Austria
Prior art keywords
deoxy
halocoformycin
chem
formula
epi
Prior art date
Application number
AT97400511T
Other languages
English (en)
Inventor
Tomio Takeuchi
Sumio Umezawa
Tsutomu Tsuchiya
Yoshiaki Takahashi
Original Assignee
Zaidan Hojin Biseibutsu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zaidan Hojin Biseibutsu filed Critical Zaidan Hojin Biseibutsu
Application granted granted Critical
Publication of ATE210676T1 publication Critical patent/ATE210676T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT97400511T 1996-03-07 1997-03-06 Verfahren zur herstellung von 2'-deoxy-2'- halocoformycin oder stereoisomere davon ATE210676T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8078084A JPH09241294A (ja) 1996-03-07 1996-03-07 ２′−デオキシ−２′−ハロコホルマイシン又はその立体異性体の製造法

Publications (1)

Publication Number Publication Date
ATE210676T1 true ATE210676T1 (de) 2001-12-15

Family

ID=13651989

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97400511T ATE210676T1 (de) 1996-03-07 1997-03-06 Verfahren zur herstellung von 2'-deoxy-2'- halocoformycin oder stereoisomere davon

Country Status (6)

Country Link
US (1) US5831072A (de)
EP (1) EP0794194B1 (de)
JP (1) JPH09241294A (de)
AT (1) ATE210676T1 (de)
DE (1) DE69708950T2 (de)
ES (1) ES2168586T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1670809B1 (de) * 2003-09-15 2016-01-13 Mayne Pharma plc Synthese und herstellung von pentostatin und vorstufen, analoga und derivaten davon
FR2881798B1 (fr) 2005-02-10 2010-08-20 Valeo Equip Electr Moteur Dispositif de demarrage d'un moteur thermique
US20100261666A1 (en) * 2009-04-14 2010-10-14 The Board Of Trustees Of The University Of Illinois Compositions and methods for the treatment of myocardial dysfunction associated with sirs or sepsis
CN113980860B (zh) * 2021-11-23 2023-09-08 天津商业大学 一种高产喷司他丁和2’-氨基-2’-脱氧腺苷的野野村菌及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923785A (en) * 1974-04-22 1975-12-02 Parke Davis & Co (R)-3-(2-deoxy-{62 -D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo{8 4,5-d{9 {8 1,3{9 diazepin-8-ol
US4117229A (en) * 1977-10-11 1978-09-26 Warner-Lambert Company 2-amino-1-(5-amino-1h-imidazol-4-yl)ethanone and method of preparation
US4713372A (en) * 1984-03-16 1987-12-15 Warner-Lambert Company 2-chloropentostatin compound having adenosine diaminase inhibitory activity
ATE34176T1 (de) * 1984-03-16 1988-05-15 Warner Lambert Co 2'-chloropentostatin, eine diese verbindung enthaltende pharmazeutische zusammensetzung und ein mikroorganismus zur herstellung dieser verbindung.
JPS61199797A (ja) * 1985-02-28 1986-09-04 Kitasato Inst:The 新規化合物アデクロリンおよびその製造法
JPH0798832B2 (ja) * 1987-05-01 1995-10-25 財団法人微生物化学研究会 イミダゾジアゼピン誘導体
NO169858C (no) * 1989-03-02 1992-08-12 Roger Sten Snarli Innretning ved rulle- eller foldesjalusi
EP0643069B1 (de) * 1991-11-14 1997-03-05 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 2'-deoxy-2'-fluorcoformycin und stereoisomere davon

Also Published As

Publication number Publication date
US5831072A (en) 1998-11-03
EP0794194A1 (de) 1997-09-10
DE69708950D1 (de) 2002-01-24
EP0794194B1 (de) 2001-12-12
DE69708950T2 (de) 2002-08-08
ES2168586T3 (es) 2002-06-16
JPH09241294A (ja) 1997-09-16

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Legal Events

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