ATE210996T1 - Antikrebs-mitoxantrone-polymer zusammensetzung - Google Patents

Antikrebs-mitoxantrone-polymer zusammensetzung

Info

Publication number
ATE210996T1
ATE210996T1 AT94102401T AT94102401T ATE210996T1 AT E210996 T1 ATE210996 T1 AT E210996T1 AT 94102401 T AT94102401 T AT 94102401T AT 94102401 T AT94102401 T AT 94102401T AT E210996 T1 ATE210996 T1 AT E210996T1
Authority
AT
Austria
Prior art keywords
mitoxantrone
cancer
polymer composition
antitumor
mve
Prior art date
Application number
AT94102401T
Other languages
English (en)
Inventor
Hwei-Ru Tsou
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ATE210996T1 publication Critical patent/ATE210996T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT94102401T 1993-03-25 1994-02-17 Antikrebs-mitoxantrone-polymer zusammensetzung ATE210996T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/037,149 US5378456A (en) 1993-03-25 1993-03-25 Antitumor mitoxantrone polymeric compositions

Publications (1)

Publication Number Publication Date
ATE210996T1 true ATE210996T1 (de) 2002-01-15

Family

ID=21892713

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94102401T ATE210996T1 (de) 1993-03-25 1994-02-17 Antikrebs-mitoxantrone-polymer zusammensetzung

Country Status (11)

Country Link
US (1) US5378456A (de)
EP (1) EP0616813B1 (de)
JP (1) JPH06321927A (de)
KR (1) KR100348380B1 (de)
AT (1) ATE210996T1 (de)
CA (1) CA2119675A1 (de)
DE (1) DE69429468T2 (de)
DK (1) DK0616813T3 (de)
ES (1) ES2169049T3 (de)
PT (1) PT616813E (de)
SG (1) SG52340A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030203976A1 (en) 1993-07-19 2003-10-30 William L. Hunter Anti-angiogenic compositions and methods of use
DE69435002T2 (de) * 1993-07-19 2008-03-20 Angiotech Pharmaceuticals, Inc., Vancouver Anti-angiogene Mittel enthaltend Taxol und einen nicht biodegradierbaren Träger und deren Verwendung
US5609867A (en) * 1994-11-01 1997-03-11 American Cyanamid Company Polymeric antitumor agents
US6624317B1 (en) 2000-09-25 2003-09-23 The University Of North Carolina At Chapel Hill Taxoid conjugates as antimitotic and antitumor agents
BR0114713A (pt) * 2000-10-16 2004-01-13 Neopharm Inc Formulação lipossÈmica de mitoxantrona
GB0123232D0 (en) * 2001-09-26 2001-11-21 Smith & Nephew Polymers
JP2010520852A (ja) * 2006-10-27 2010-06-17 ジュセッペ・トリジャンテ 除毛(脱毛)のための化合物と方法
CA2938626A1 (en) 2013-07-26 2015-01-29 John Rothman Compositions to improve the therapeutic benefit of bisantrene
US20240269092A1 (en) * 2021-05-28 2024-08-15 Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd Use of mitoxantrone hydrochloride liposome in preparation of drugs for treating advanced solid tumors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182800A (en) * 1977-07-16 1980-01-08 Hercules Incorporated Methotrexate-divinyl ether--maleic anhydride copolymer reaction product
US4520162A (en) * 1983-09-24 1985-05-28 Director-General Of The Agency Of Industrial Science & Technology Polymeric compounds with sustained anti-tumor activity and a method for the preparation thereof
JPS6067490A (ja) * 1983-09-24 1985-04-17 Agency Of Ind Science & Technol アントラサイクリン系抗生物質誘導体及びその製造方法
JPS6067426A (ja) * 1983-09-24 1985-04-17 Agency Of Ind Science & Technol 低毒性制ガン剤
GB8413464D0 (en) * 1984-05-25 1984-07-04 Erba Farmitalia Anthracycline-anionic polymer conjugates
DE3768419D1 (de) * 1986-10-07 1991-04-11 Boehringer Biochemia Srl Pharmazeutische zusammensetzungen mit antineoplastischer wirkung.
PT93772A (pt) * 1989-04-17 1991-01-08 Searle & Co Processo para a preparacao de composicoes para o tratamento de neoplasias, contendo um agente anti-neoplastico, por exemplo doxorubicina e um agente protector para reduzir os efeitos secundarios, por exemplo carbetimer
JPH0762049B2 (ja) * 1991-03-18 1995-07-05 工業技術院長 高分子マイトマイシンc誘導体及びその製造方法
JP3069646B2 (ja) * 1991-05-28 2000-07-24 三共株式会社 5−フルオロウリジン−高分子複合体

Also Published As

Publication number Publication date
EP0616813A2 (de) 1994-09-28
PT616813E (pt) 2002-06-28
ES2169049T3 (es) 2002-07-01
DE69429468T2 (de) 2002-08-14
KR940021068A (ko) 1994-10-17
US5378456A (en) 1995-01-03
EP0616813B1 (de) 2001-12-19
DK0616813T3 (da) 2002-04-15
EP0616813A3 (de) 1995-03-29
CA2119675A1 (en) 1994-09-26
SG52340A1 (en) 1998-09-28
JPH06321927A (ja) 1994-11-22
KR100348380B1 (ko) 2004-03-25
DE69429468D1 (de) 2002-01-31

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee