ATE211483T1 - Verbindungen, die die serotoninerge übertragung beeinflussen; ihre diagnostischen und therapeutischen anwendungen - Google Patents

Verbindungen, die die serotoninerge übertragung beeinflussen; ihre diagnostischen und therapeutischen anwendungen

Info

Publication number: ATE211483T1
Authority: AT; Austria
Prior art keywords: compounds; peptide; leu; diagnostic; affect
Prior art date: 1993-10-04

Application number

AT94929577T

Other languages

English (en)

Inventor

Gilles Fillion

Jean-Claude Rousselle

Olivier Massot

Original Assignee

Pasteur Institut

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-04

Filing date

1994-10-04

Publication date

2002-01-15

1993-10-04 Priority claimed from FR9311804A external-priority patent/FR2710916B1/fr

1994-06-09 Priority claimed from FR9407079A external-priority patent/FR2721030B1/fr

1994-06-09 Priority claimed from FR9407078A external-priority patent/FR2721029B1/fr

1994-10-04 Application filed by Pasteur Institut filed Critical Pasteur Institut

2002-01-15 Application granted granted Critical

2002-01-15 Publication of ATE211483T1 publication Critical patent/ATE211483T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 4
230000005540 biological transmission Effects 0.000 title 1
230000002295 serotoninergic effect Effects 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 6
230000007515 enzymatic degradation Effects 0.000 abstract 2
DCVYRWFAMZFSDA-ZLUOBGJFSA-N Ala-Ser-Ala Chemical compound [H]N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(O)=O DCVYRWFAMZFSDA-ZLUOBGJFSA-N 0.000 abstract 1
IRMLZWSRWSGTOP-CIUDSAMLSA-N Leu-Ser-Ala Chemical compound CC(C)C[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(O)=O IRMLZWSRWSGTOP-CIUDSAMLSA-N 0.000 abstract 1
108091005804 Peptidases Proteins 0.000 abstract 1
239000004365 Protease Substances 0.000 abstract 1
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Motor Or Generator Cooling System (AREA)

AT94929577T 1993-10-04 1994-10-04 Verbindungen, die die serotoninerge übertragung beeinflussen; ihre diagnostischen und therapeutischen anwendungen ATE211483T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR9311804A FR2710916B1 (fr)	1993-10-04	1993-10-04	Composés de nature peptidique ayant une activité modulatrice de la réponse sérotoninergique; applications diagnostiques et thérapeutiques.
FR9407079A FR2721030B1 (fr)	1994-06-09	1994-06-09	Composés modifiant la transmission sérotoninergique; applications diagnostiques et thérapeutiques.
FR9407078A FR2721029B1 (fr)	1994-06-09	1994-06-09	Composés modifiant la transmission sérotoninergique; applications diagnostiques et thérapeutiques.
PCT/FR1994/001158 WO1995009868A1 (fr)	1993-10-04	1994-10-04	Composes modifiant la transmission serotoninergique; applications diagnostiques et therapeutiques

Publications (1)

Publication Number	Publication Date
ATE211483T1 true ATE211483T1 (de)	2002-01-15

Family

ID=27252801

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94929577T ATE211483T1 (de)	1993-10-04	1994-10-04	Verbindungen, die die serotoninerge übertragung beeinflussen; ihre diagnostischen und therapeutischen anwendungen

Country Status (12)

Country	Link
US (1)	US6713443B1 (de)
EP (1)	EP0722457B1 (de)
JP (1)	JPH09503220A (de)
KR (1)	KR960704921A (de)
AT (1)	ATE211483T1 (de)
AU (1)	AU678298B2 (de)
CA (1)	CA2173460A1 (de)
DE (1)	DE69429582T2 (de)
DK (1)	DK0722457T3 (de)
ES (1)	ES2170105T3 (de)
PT (1)	PT722457E (de)
WO (1)	WO1995009868A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6759510B1 (en)	2000-06-30	2004-07-06	Becton, Dickinson And Company	Peptides for use in culture media
TWI411441B (zh) *	2003-03-18	2013-10-11	Suntory Holdings Ltd	血管收縮素轉化酶抑制性肽類

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5647895B2 (de) *	1973-06-08	1981-11-12
WO1980002157A1 (en)	1979-04-06	1980-10-16	Forenede Bryggerier As	A process for enzymatic production of peptides
US4793986A (en) *	1987-02-25	1988-12-27	Johnson Matthey, Inc.	Macromolecular platinum antitumor compounds
SE8803847A0 (sv)	1988-10-27	1990-04-28	Kabigen Ab	Neuromodulerande peptid
US5104854A (en) *	1989-02-01	1992-04-14	Washington University	Antiviral peptides
FR2657784A1 (fr)	1990-02-05	1991-08-09	Pasteur Institut	Facteur endogene cerebral, procede d'obtention et applications therapeutiques et diagnostiques.
JPH0421635A (ja) *	1990-05-16	1992-01-24	Suntory Ltd	アセトアルデヒドの毒性抑制剤およびアセトアルデヒドの毒性抑制に有効な飲食物

1994
- 1994-10-04 ES ES94929577T patent/ES2170105T3/es not_active Expired - Lifetime
- 1994-10-04 AT AT94929577T patent/ATE211483T1/de not_active IP Right Cessation
- 1994-10-04 EP EP94929577A patent/EP0722457B1/de not_active Expired - Lifetime
- 1994-10-04 KR KR1019960701742A patent/KR960704921A/ko not_active Withdrawn
- 1994-10-04 DE DE69429582T patent/DE69429582T2/de not_active Expired - Fee Related
- 1994-10-04 WO PCT/FR1994/001158 patent/WO1995009868A1/fr not_active Ceased
- 1994-10-04 PT PT94929577T patent/PT722457E/pt unknown
- 1994-10-04 CA CA002173460A patent/CA2173460A1/fr not_active Abandoned
- 1994-10-04 AU AU78579/94A patent/AU678298B2/en not_active Ceased
- 1994-10-04 DK DK94929577T patent/DK0722457T3/da active
- 1994-10-04 JP JP7510646A patent/JPH09503220A/ja active Pending
- 1994-10-04 US US08/624,618 patent/US6713443B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0722457A1 (de)	1996-07-24
AU7857994A (en)	1995-05-01
ES2170105T3 (es)	2002-08-01
WO1995009868A1 (fr)	1995-04-13
DE69429582T2 (de)	2002-08-22
JPH09503220A (ja)	1997-03-31
AU678298B2 (en)	1997-05-22
CA2173460A1 (fr)	1995-04-13
PT722457E (pt)	2002-06-28
US6713443B1 (en)	2004-03-30
EP0722457B1 (de)	2002-01-02
KR960704921A (ko)	1996-10-09
DK0722457T3 (da)	2002-04-22
DE69429582D1 (de)	2002-02-07

Legal Events

Date	Code	Title	Description
2005-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
EP1571199A3 (de)	2006-01-11	Reinigungsmittel enthaltend mehrfach substituierte protease Varianten
CA2173973A1 (en)	1995-04-20	Subtilisin variants
CA2173106A1 (en)	1995-04-20	Bleaching Compositions Comprising Protease Enzymes
CA2214348A1 (en)	1996-09-19	Subtilisin carlsberg variants having decreased adsorption and increased hydrolysis
TW223018B (en)	1994-05-01	Salts of peptides with carboxy-terminated polyesters
CA2193061A1 (en)	1996-01-25	Fractionated polydisperse compositions
CA2111645A1 (en)	1994-06-18	Fibrinogen fragment e peptides and antibodies thereto
AU2003231471A1 (en)	2003-11-10	Antimicrobial polypeptide and utizliation thereof
CA2021379A1 (en)	1991-01-19	Pentapeptide antibiotics derived from dalbaheptides
EP1681350A3 (de)	2007-07-18	Polypeptiden und Nukleinsäuren von Phorphorymonas gingivalis
EP1006126A3 (de)	2000-10-25	Peptide mit osteogener Aktivität
ES8705893A1 (es)	1987-05-16	Un procedimiento para preparar derivados monoamidicos basicos de actagardina
DE69429582D1 (de)	2002-02-07	Verbindungen, die die serotoninerge übertragung beeinflussen; ihre diagnostischen und therapeutischen anwendungen
AU3850997A (en)	1998-03-06	Immunologically active proteins of borrelia burgdorferi, coded nuclein acids of such and their use in test kits and vaccines
DE69722618D1 (en)	2003-07-10	Peptide
CA2001265A1 (en)	1990-04-28	Analogs of peptidase substrates
MX9706846A (es)	1997-11-29	Variantes de termitasa que tienen adsorcion reducida e hidrolisis incrementada.
HUP9701290A2 (hu)	1999-06-28	Javított tulajdonságú aprotininváltozatok
CA2133834A1 (en)	1993-10-14	Process for preparing modified proteins
CA2077606A1 (en)	1993-04-10	Inhibited 141b
MX9602836A (es)	1997-01-31	MEZCLA QUE CONTIENE UNO O VARIOS ALFA-AMINOACIDOS Y SUS DERIVADOS, O AMBOS, Y UNO O VARIOS CICLOPENTANO- beta-AMINOACIDOS Y SUS DERIVADOS, O AMBOS.
WO2002085934A3 (fr)	2003-11-06	Peptides antibacteriens, les compositions les contenant et leurs utilisations
AU3674889A (en)	1990-01-04	Peptide molecules with activity against gram positive microorganisms
AU7209594A (en)	1995-01-17	Anti-inflammatory peptides
WO2025255366A3 (en)	2026-02-05	Lyophilized and sprayable silk fibroin and modified silk fibroin forms